4.4 Article

Synthesis of Benzotriazole Analogues of the Helicobactericidal Agents CJ-13,015, CJ-13,102, CJ-13,108, and CJ-13,104 Using a Regioselective 1,3-Dipolar Cycloaddition

Journal

SYNLETT
Volume -, Issue 1, Pages 99-103

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1259081

Keywords

benzotriazole; helicobacter pylori; benzyne; dipolar cycloaddition

Funding

  1. University of Auckland
  2. Maurice Wilkins Centre for Molecular Biodiscovery

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A regioselective 1,3-dipolar cycloaddition of a disubstituted aryne and various alkyl azides facilitates access to benzotriazole analogues of several anti-Helicobacter pylori antibiotics.

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