4.4 Article

One-Pot, Three-Component Synthesis of 4-Aryl-5,6-dihydropyran via Prins-Friedel-Crafts Reaction

Journal

SYNLETT
Volume -, Issue 7, Pages 1027-1032

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1219779

Keywords

Lewis acid; multicomponent; Prins cyclization; Friedel-Crafts reaction; dihydropyran

Funding

  1. Department of Science and Technology (DST), New Delhi [SR/S1/OC-33/2007]
  2. Council of Scientific & Industrial Research (CSIR)

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An efficient method for the synthesis of 4-aryldihydropyrans has been developed from the reaction of aldehydes or epoxides with homopropargylic alcohols in the presence of arenes promoted by boron trifluoride etherate

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