4.4 Article

Enantioselective Mannich-Type Reaction Catalyzed by a Chiral Phosphoric Acid Bearing an (S)-Biphenol Backbone

Journal

SYNLETT
Volume -, Issue 10, Pages 1664-1666

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1217330

Keywords

asymmetric synthesis; chiral Bronsted acid; Mannich-type reaction; biphenol; phosphoric acid

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A novel chiral phosphoric acid bearing a biphenol backbone was synthesized and its catalytic activity was investigated in the enantioselective Mannich-type reaction of ketene silyl acetals with aldimines.

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