Journal
SYNLETT
Volume -, Issue 13, Pages 2191-2197Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1217549
Keywords
cinchona alkaloid; formal [3+2] cycloaddition; alpha-aryl isocyanoester; aldehydes; chiral oxazolines
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Funding
- NSFC [20732006]
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A cinchona alkaloid derivative catalyzed the asymmetric formal [3+2] cycloaddition of alpha-aryl isocyanoesters with aldehydes, affording highly substituted 2-oxazolines with good stereoselectivities of up to 18:1 dr and 90% ee.
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