Journal
SYNLETT
Volume -, Issue 20, Pages 3115-3120Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0028-1087417
Keywords
three component; benzyne; aryne; pyrido[2,1-a]isoindole
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Funding
- Zhejiang Provincial Natural Science Foundation of China [R407106]
- Natural Science Foundation of China [20571063]
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A novel three-component assembly involving benzynes has been developed for the synthesis of pyrido[2,1-a]isoindoles in moderate yields. Reaction conditions have been optimized and the scope of the reaction has been studied. A plausible mechanism has been proposed to account for the three-component reaction.
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