4.4 Article

Enantioselective synthesis of 3,3-disubstituted indolines via asymmetric intramolecular carbolithiation in the presence of (-)-sparteine

Journal

SYNLETT
Volume -, Issue 9, Pages 1301-1304

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2008-1072630

Keywords

asymmetric synthesis; indolines; lithiations; natural products; sparteine

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The functionalized N-benzyl-protected bromoanilines underwent an asymmetric intramolecular carbolithiation in the presence of t-BuLi and (-)-sparteine yielding 3,3-disubstituted indolines.

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