Targeting Glia with N-Acetylcysteine Modulates Brain Glutamate and Behaviors Relevant to Neurodevelopmental Disorders in C57BL/6J Mice

Behaviour and prefrontal protein differences in C57BL/6N and 129 X1/SvJ mice

(2015) Xiaofan Zhang et al.   BRAIN RESEARCH BULLETIN

“Brain MR spectroscopy in autism spectrum disorder—the GABA excitatory/inhibitory imbalance theory revisited”

(2015) Maiken K. Brix et al.   Frontiers in Human Neuroscience

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

(2015) J L Silverman et al.   NEUROPSYCHOPHARMACOLOGY

Fronto-striatal glutamatergic compounds in compulsive and impulsive syndromes: A review of magnetic resonance spectroscopy studies

(2015) Jilly Naaijen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Activation of the prelimbic medial prefrontal cortex induces anxiety-like behaviors via N-Methyl-D-aspartate receptor-mediated glutamatergic neurotransmission in mice

(2014) Akiyoshi Saitoh et al.   JOURNAL OF NEUROSCIENCE RESEARCH

N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action

(2014) Olivia Dean et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

SYSTEMATIC REVIEW OF THE PREVALENCE AND RISK FACTORS FOR INTERPERSONAL VIOLENCE IN ACUTE PSYCHIATRIC UNITS

(2014) Giovanni de Girolamo et al.   SCHIZOPHRENIA RESEARCH

A randomized double blind placebo controlled clinical trial of N-Acetylcysteine added to risperidone for treating autistic disorders

(2013) Ahmad Ghanizadeh et al.   BMC Psychiatry

Targeting Glia Cells: Novel Perspectives for the Treatment of Neuropsychiatric Diseases

(2013) B. Benedetto et al.   Current Neuropharmacology

The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety

(2013) Vasilios Grivas et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glutamate-based anxiolytic ligands in clinical trials

(2013) Joanna M Wierońska et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

A Matter of Balance: Role of Neurexin and Neuroligin at the Synapse

(2013) Marie Louise Bang et al.   NEUROCHEMICAL RESEARCH

Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits

(2013) Gordon F. Rushworth et al.   PHARMACOLOGY & THERAPEUTICS

Altered Social Behaviours in Neurexin 1α Knockout Mice Resemble Core Symptoms in Neurodevelopmental Disorders

(2013) Hannah Mary Grayton et al.   PLoS One

Anxiety comorbidity in schizophrenia

(2013) Raphael J. Braga et al.   PSYCHIATRY RESEARCH

Chronic high fat diet consumption impairs sensorimotor gating in mice

(2013) Marie A. Labouesse et al.   PSYCHONEUROENDOCRINOLOGY

Erratum: Neurotransmitter signaling in the pathophysiology of microglia

(2013) María Domercq et al.   Frontiers in Cellular Neuroscience

Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [1H]MRS study

(2013) J Horder et al.   Translational Psychiatry

The role of the striatum in social behavior

(2013) Raymundo Báez-Mendoza et al.   Frontiers in Neuroscience

A Randomized Controlled Pilot Trial of Oral N-Acetylcysteine in Children with Autism

(2012) Antonio Y. Hardan et al.   BIOLOGICAL PSYCHIATRY

Genetic architecture in autism spectrum disorder

(2012) Bernie Devlin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Absolute quantitation of brain metabolites with respect to heterogeneous tissue compositions in 1H-MR spectroscopic volumes

(2012) Alexander Gussew et al.   MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

GABA system dysfunction in autism and related disorders: From synapse to symptoms

(2012) Suzanne Coghlan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Magnetic resonance spectroscopy reveals N-acetylaspartate reduction in hippocampus and cingulate cortex after fear conditioning

(2012) Iris Y. Zhou et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

N-ACETYLCYSTEINE NORMALIZES NEUROCHEMICAL CHANGES IN THE GLUTATHIONE-DEFICIENT SCHIZOPHRENIA MOUSE MODEL DURING DEVELOPMENT

(2012) Anita Kulak   SCHIZOPHRENIA RESEARCH

Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism

(2012) J. L. Silverman et al.   Science Translational Medicine

Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders

(2012) Will Spooren et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Social and monetary reward processing in autism spectrum disorders

(2012) Sonja Delmonte et al.   Molecular Autism

Glutamatergic Modulation of Auditory Information Processing in the Human Brain

(2011) Handan Gunduz-Bruce et al.   BIOLOGICAL PSYCHIATRY

The Effect of N-Acetylcysteine in the Nucleus Accumbens on Neurotransmission and Relapse to Cocaine

(2011) Yonatan M. Kupchik et al.   BIOLOGICAL PSYCHIATRY

Nurr1 is not essential for the development of prepulse inhibition deficits induced by prenatal immune activation

(2011) Stéphanie Vuillermot et al.   BRAIN BEHAVIOR AND IMMUNITY

The role of immune dysfunction in the pathophysiology of autism

(2011) Charity Onore et al.   BRAIN BEHAVIOR AND IMMUNITY

Higher Levels of Glutamate in the Associative-Striatum of Subjects with Prodromal Symptoms of Schizophrenia and Patients with First-Episode Psychosis

(2011) Camilo de la Fuente-Sandoval et al.   NEUROPSYCHOPHARMACOLOGY

From Revolution to Evolution: The Glutamate Hypothesis of Schizophrenia and its Implication for Treatment

(2011) Bita Moghaddam et al.   NEUROPSYCHOPHARMACOLOGY

Pharmacological effects of metabotropic glutamate receptor ligands on prepulse inhibition in DBA/2J mice

(2010) Hirohiko Hikichi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A Possible Role for the Striatum in the Pathogenesis of the Cognitive Symptoms of Schizophrenia

(2010) Eleanor H. Simpson et al.   NEURON

Altered neuroligin expression is involved in social deficits in a mouse model of the fragile X syndrome

(2009) Regina Dahlhaus et al.   BEHAVIOURAL BRAIN RESEARCH

Prevalence of autism-spectrum conditions: UK school-based population study

(2009) Simon Baron-Cohen et al.   BRITISH JOURNAL OF PSYCHIATRY

A Role for Glutathione in the Pathophysiology of Bipolar Disorder and Schizophrenia? Animal Models and Relevance to Clinical Practice

(2009) O. Dean et al.   CURRENT MEDICINAL CHEMISTRY

Glial cells in schizophrenia: pathophysiological significance and possible consequences for therapy

(2009) Hans-Gert Bernstein et al.   Expert Review of Neurotherapeutics

Gender differences in prepulse inhibition (PPI) in bipolar disorder: men have reduced PPI, women have increased PPI

(2009) Andrea Gogos et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The pathophysiology of restricted repetitive behavior

(2009) Mark Lewis et al.   Journal of Neurodevelopmental Disorders

Pharmacological Effects of the Metabotropic Glutamate Receptor 1 Antagonist Compared with Those of the Metabotropic Glutamate Receptor 5 Antagonist and Metabotropic Glutamate Receptor 2/3 Agonist in Rodents: Detailed Investigations with a Selective Allosteric Metabotropic Glutamate Receptor 1 Antagonist, FTIDC [4-[1-(2-Fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide]

(2008) A. Satow et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Expression of astrocytic markers aquaporin 4 and connexin 43 is altered in brains of subjects with autism

(2008) S. Hossein Fatemi et al.   SYNAPSE