Organotypic vibrosections from whole brain adult Alzheimer mice (overexpressing amyloid-precursor-protein with the Swedish-Dutch-Iowa mutations) as a model to study clearance of beta-amyloid plaques

Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β

(2013) Simon J. Henderson et al.   BRAIN

Recombinant soluble neprilysin reduces amyloid-beta accumulation and improves memory impairment in Alzheimer's disease mice

(2013) Min Hee Park et al.   BRAIN RESEARCH

Enhanced Proteolytic Clearance of Plasma A  by Peripherally Administered Neprilysin Does Not Result in Reduced Levels of Brain A  in Mice

(2013) J. R. Walker et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial Alterations near Amyloid Plaques in an Alzheimer's Disease Mouse Model

(2013) Hong Xie et al.   JOURNAL OF NEUROSCIENCE

Intravenous infusion of nerve growth factor-secreting monocytes supports the survival of cholinergic neurons in the nucleus basalis of meynert in hypercholesterolemia brown-norway rats

(2013) Lindsay A. Hohsfield et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Nardilysin prevents amyloid plaque formation by enhancing α-secretase activity in an Alzheimer's disease mouse model

(2013) Mikiko Ohno et al.   NEUROBIOLOGY OF AGING

Ketamine reduces amyloid β-protein degradation by suppressing neprilysin expression in primary cultured astrocytes

(2013) Naoki Yamamoto et al.   NEUROSCIENCE LETTERS

Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer’s Disease

(2013) Marcus O. W. Grimm et al.   Frontiers in Aging Neuroscience

Estrogen activates matrix metalloproteinases-2 and -9 to increase beta amyloid degradation

(2012) Sara Merlo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Identification of BACE2 as an avid ß-amyloid-degrading protease

(2012) Samer O Abdul-Hay et al.   Molecular Neurodegeneration

Organotypic Brain Slice Cultures of Adult Transgenic P301S Mice—A Model for Tauopathy Studies

(2012) Agneta Mewes et al.   PLoS One

Organotypic hippocampal slice culture from the adult mouse brain: A versatile tool for translational neuropsychopharmacology

(2012) Hyunjeong Kim et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Neprilysin-2 Is an Important β-Amyloid Degrading Enzyme

(2011) Daniel Hafez et al.   AMERICAN JOURNAL OF PATHOLOGY

Neprilysin Protects against Cerebral Amyloid Angiopathy and Aβ-Induced Degeneration of Cerebrovascular Smooth Muscle Cells

(2011) James Scott Miners et al.   BRAIN PATHOLOGY

Evaluation of cell damage in organotypic hippocampal slice culture from adult mouse: A potential model system to study neuroprotection

(2011) Tao Su et al.   BRAIN RESEARCH

BRI2 Protein Regulates β-Amyloid Degradation by Increasing Levels of Secreted Insulin-degrading Enzyme (IDE)

(2011) Ellen Kilger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Organotypic vibrosections: Novel whole sagittal brain cultures

(2011) Celine Ullrich et al.   JOURNAL OF NEUROSCIENCE METHODS

The role of microglia in amyloid clearance from the AD brain

(2010) C. Y. Daniel Lee et al.   JOURNAL OF NEURAL TRANSMISSION

Trafficking CD11b-Positive Blood Cells Deliver Therapeutic Genes to the Brain of Amyloid-Depositing Transgenic Mice

(2010) L. Lebson et al.   JOURNAL OF NEUROSCIENCE

An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies

(2010) Deborah A. Ryan et al.   JOURNAL OF NEUROSCIENCE METHODS

Circulating neprilysin clears brain amyloid

(2010) Yinxing Liu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Degradation of Amyloid β Protein by Purified Myelin Basic Protein

(2009) Mei-Chen Liao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-Degrading Enzymes as Therapeutic Targets in Alzheimers Disease

(2008) Natalia Nalivaeva et al.   Current Alzheimer Research

Amyloid-Degrading Ability of Nattokinase fromBacillus subtilisNatto

(2008) Ruei-Lin Hsu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Peripherally expressed neprilysin reduces brain amyloid burden: A novel approach for treating Alzheimer's disease

(2008) Hanjun Guan et al.   JOURNAL OF NEUROSCIENCE RESEARCH