Article
Forestry
Claudia Lizbeth Ramirez-Orozco, Jose Ciro Hernandez-Diaz, Artemio Carrillo-Parra, Christian Wehenkel, Carmen Zulema Quinones-Perez, Carlos A. Lopez-Sanchez, Claudia Edith Bailon-Soto
Summary: This study evaluated the genetic diversity and differentiation of six major pine species in the Sierra Madre Occidental, northern Mexico. The elevation and center-periphery model were found to be important factors influencing genetic diversity.
Article
Geosciences, Multidisciplinary
Gerardo J. Aguirre-Diaz, Margarito Tristan-Gonzalez, Isaac Gutierrez-Palomares, Joan Marti, Margarita Lopez-Martinez, Guillermo Labarthe-Hernandez, Jorge Nieto-Obregon
Summary: Graben calderas are volcano-tectonic structures that use graben faults as main vents for magma eruption. These eruptions are usually silicic and explosive, forming large ignimbrite sheets. The Bolanos graben caldera in western Mexico is an example of this type and is the second largest caldera in the world.
JOURNAL OF VOLCANOLOGY AND GEOTHERMAL RESEARCH
(2021)
Article
Plant Sciences
Alejandro Leal-Saenz, Kristen M. Waring, Rebeca Alvarez-Zagoya, Jose Ciro Hernandez-Diaz, Carlos A. Lopez-Sanchez, Jose Hugo Martinez-Guerrero, Christian Wehenkel
Summary: The study analyzed insect damage to cones and seeds of P. strobiformis in Mexico, finding that a majority of seeds and all tree populations studied were affected by insects, mainly including Leptoglossus occidentalis, Tetyra bipunctata, Megastigmus albifrons, and various Lepidoptera species. The damage may have significant impacts on seed production and reforestation potential of P. strobiformis.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biodiversity Conservation
A. Abadia-Cardoso, R. Hernandez-Guzman, A. Varela-Romero, J. C. Garza, F. J. Garcia-De Leon
Summary: Recent climatic conditions are influencing biodiversity, particularly in isolated species like trout inhabiting the Northern Sierra Madre Occidental in Mexico. Genetic analysis revealed two distinct subgroups within the trout population, with limited connectivity possibly explaining the current diversity arrangement. Environmental factors were found to play a significant role in shaping the genetic structure.
CONSERVATION GENETICS
(2021)
Article
Plant Sciences
Heriberto Avila-Gonzalez, Jesus Guadalupe Gonzalez-Gallegos, Guadalupe Munguia-Lino, Arturo Castro-Castro
Summary: Several taxonomic novelties of the genus Sisyrinchium have been presented recently. A new species, Sisyrinchium jacquelineanum, was discovered in northwestern Mexico during a floristic inventory in a Natural Protected Area. It differs morphologically from the most similar species, S. polycladum, in terms of growth habit, position of root thickenings, absence of fibrous remnants of old leaves at the base of the stem, flower size, and capsule shape and pubescence. An identification key for the 16 species of Sisyrinchium in the Sierra Madre Occidental and their richness patterns are also provided.
Article
Plant Sciences
Ivon Ramirez-Morillo, Pablo Carrillo-Reyes, Jose Luis Tapia-Munoz, Claudia J. Ramirez-Diaz
Summary: Epitypes are proposed for two species of Hechtia endemic to Western Mexico: H. subalata and H. jaliscana. A new species, Hechtia marthae, previously misidentified as Hechtia subalata, is identified from Durango, Mexico. Images portraying plant parts of all species, as well as habitat photographs, are provided along with assessments of the conservation status of the three species based on IUCN criteria.
Article
Energy & Fuels
Juan Carlos Castillo Reynoso, Luca Ferrari, Andrea Billarent-Cedillo, Gilles Levresse, Claudio Inguaggiato
Summary: This study focuses on the thermal activity in the central part of the Sierra Madre Occidental in western Mexico. The anomalous water temperature of the thermal springs in this region is likely caused by heat production from radioactive decay, convection through deeply rooted faults, and the intersection of regional structures. The findings provide valuable insights into the geothermal system in this area.
Article
Biodiversity Conservation
Carlos Enrique Aguirre-Calderon, Armando Sanchez-Escalera, Irene Ruvalcaba-Ortega, Cristobal Gerardo Aguirre-Calderon, Benedicto Vargas-Larreta, Francisco J. Hernandez, Ricardo Canales-del-Castillo, Jose Ignacio Gonzalez Rojas
Summary: The Sierra Madre Sparrow is an endangered Mexican endemic bird that inhabits bunchgrassland areas. The survey conducted in the Sierra Madre Occidental region of Mexico revealed a total of 193 individuals, with seven previously unknown localities. The total area of bunchgrass in meadows was found to be a significant predictor of the bird's presence.
BIRD CONSERVATION INTERNATIONAL
(2022)
Article
Plant Sciences
Arturo Castro-castro, Marco Antonio Gonzalez-bernal, Edmi Itzel Rojas-Aguilar
Summary: Botanical explorations in Sierra Madre Occidental, Mexico led to the discovery of new populations of Polianthes montana in the southern part of Durango state. Due to its limited knowledge and conflicting identification and distribution range, this study provides discussions and a detailed morphological description. Additionally, specimens collected near the border of Durango and Sinaloa states were found to be a new species that resembles P. alboaustralis and P. montana but differs in various morphological characteristics. The article includes photographs, phenology notes, geographic distribution, conservation status, habitat information, as well as a map and an identification key.
Article
Geography, Physical
Arturo Godinez-Tamay, Miguel Castillo, Luca Ferrari, Fernando Ortega-Gutierrez
Summary: This study analyzed the perched landscape surfaces in the southern sector of Sierra Madre Occidental to confirm their relict status. The findings indicate that the knickpoints near the main fault escarpments do not show significant differences in elevation, retreat distance, and time of migration, suggesting the presence of a relict landscape coexisting with ongoing tectonic activity.
Article
Geosciences, Multidisciplinary
M. C. Jaimes-Viera, G. J. Aguirre-Diaz, M. Tristan-Gonzalez, A. Aguillon-Robles, J. H. Serna-Bafun, B. A. Ramirez-Cruz
Summary: This study focuses on two widespread Oligocene ignimbrite sheets and numerous lava domes in the southeastern portion of the Sierra Madre Occidental, providing data on their distribution, stratigraphy, geochronology, textures, and geochemistry. The ignimbrites are named Victoria I and Victoria II, with distinct characteristics in mineral composition and texture. Zircon U-Pb ages indicate the formation ages of the ignimbrites and associated lava domes, contributing to a better understanding of the volcanic history in the region.
JOURNAL OF SOUTH AMERICAN EARTH SCIENCES
(2022)
Article
Plant Sciences
A. Fabian J-Perez, Miguel Angel Perez-Farrera, Pedro Diaz Jimenez, Mauricio Geronimo Martinez-Martinez
Summary: During fieldwork conducted between 2020 and 2022 in the Sierra Madre of Chiapas, a previously undescribed species of Spathiphyllum, named S. frailescanense, was discovered. It is similar to S. matudae in morphology but differs in several characteristics such as shorter petioles, lanceolate or elliptic-lanceolate blades, fewer pairs of primary veins, stipitate spadix, and constriction between the ovary and the style.
Article
Ecology
Celia Lopez Gonzalez, Sarahi Sandoval, Jonathan G. Escobar Flores
Summary: This study generated niche models for 33 species of small, non-flying mammals in the Sierra Madre Occidental using Maxent and high-resolution physiographic layers. The resulting ecoregionalization proposed two major regions, tropical and xerophilous, with a transitional region between them. The complexity of the Sierra Madre Occidental goes beyond traditional subdivision based on the Nearctic-Neotropical division.
Article
Plant Sciences
Juan F. Pio-Leon, Arturo Castro-Castro, Leonardo O. Alvarado-Cardenas
Summary: This paper describes a new species of Gonolobus, named Gonolobus gonzaleriarum, found in two forests in the states of Sinaloa and Durango, Mexico. It differs from other species in the subgenus Pseudolachnostoma by having a reduced stipe, lobes of the corolla and sepals of shorter length than the tube, citrus aroma, and a dense inflorescence. It is considered a threatened species due to its limited distribution and impacted habitat.
ACTA BOTANICA MEXICANA
(2023)
Article
Plant Sciences
Miguel A. Perez-Perez, Tina J. Ayers, Jonathan D. Amith
Summary: This article describes a new species, Lobelia alanae, found in Puebla and Veracruz, Mexico. Through comparison, it is found that Lobelia alanae can be distinguished from Lobelia porphyrea by its height, hypanthium, calyx lobes, and fruit. By examining the reticulate-foveolate seed coats, it is hypothesized that Lobelia alanae belongs to the Lobelia section, which previously consisted of 22 species almost endemic to the eastern U.S.
Article
Oncology
Peter H. J. Slootbeek, Marleen L. Duizer, Maarten J. van Der Doelen, Iris S. H. Kloots, Malou C. P. Kuppen, Hans M. Westgeest, Carin A. Uyl-de Groot, Samhita Pamidimarri Naga, Marjolijn J. L. Ligtenberg, Inge M. van Oort, Winald R. Gerritsen, Jack A. Schalken, Leonie I. Kroeze, Haiko J. Bloemendal, Niven Mehra
Summary: Platinum-based chemotherapy is not the standard treatment for metastatic castration-resistant prostate cancer patients. This study found that patients with BRCA2 mutations had meaningful responses to carboplatin, suggesting a potential role for both PARPi and platinum-based chemotherapy in preselected mCRPC patients. Despite the poor prognosis for AVPC patients, they showed comparable responses to non-AVPC patients in terms of overall survival and treatment response.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Letter
Medical Laboratory Technology
Maartje J. Geerlings, Lisa S. M. Hofste, Eveline J. Kamping, Zumaya Abdi, Sofie H. Tolmeijer, Linda M. Garms, Bastiaan R. Klarenbeek, Marjolijn J. L. Ligtenberg
CLINICAL CHEMISTRY
(2021)
Editorial Material
Gastroenterology & Hepatology
Femke Simmer, Ragna L. A. van der Linden, Marjolijn J. L. Ligtenberg, Bauke Ylstra, Rachel S. van der Post, Iris D. Nagtegaal
Article
Oncology
Bastiaan M. Prive, Peter H. J. Slootbeek, Babette Laarhuis, Samhita Pamidimarri Naga, Maarten J. van Der Doelen, Ludwike W. M. van Kalmthout, Bart de Keizer, Samer Ezziddin, Clemens Kratochwil, Alfred Morgenstern, Frank Bruchertseifer, Marjolijn J. L. Ligtenberg, J. Alfred Witjes, Inge M. van Oort, Martin Gotthardt, Sandra Heskamp, Marcel J. R. Janssen, Winald R. Gerritsen, James Nagarajah, Niven Mehra
Summary: This study found that in mCRPC patients undergoing DDR gene testing and receiving PSMA-RLT treatment, tumors with DDR abnormalities do not necessarily show better treatment responses.
PROSTATE CANCER AND PROSTATIC DISEASES
(2022)
Article
Oncology
Peter H. J. Slootbeek, Iris S. H. Kloots, Minke Smits, Inge M. van Oort, Winald R. Gerritsen, Jack A. Schalken, Marjolijn J. L. Ligtenberg, Katrien Grunberg, Leonie Kroeze, Haiko J. Bloemendal, Niven Mehra
Summary: The study found that almost half of advanced prostate cancer patients receive recommendations for genetically matched therapies, with over 40% of them showing durable responses to the treatment. These findings support the routine referral of selected prostate cancer patients to molecular tumour boards.
BRITISH JOURNAL OF CANCER
(2022)
Article
Pathology
Elisabeth M. P. Steeghs, Geraldine R. Vink, Marloes A. G. Elferink, Quirinus J. M. Voorham, Hans Gelderblom, Iris D. Nagtegaal, Katrien Grunberg, Marjolijn J. L. Ligtenberg
Summary: The study in the Netherlands showed an increase in mutation testing rates for CRC patients over time, with anti-EGFR therapy mainly used in KRAS/NRAS wild-type patients after the third treatment line. The national average mutation rate was 63.9%, and NGS-based approaches detected more potential biomarkers.
JOURNAL OF CLINICAL PATHOLOGY
(2022)
Article
Pathology
Valentyna Kryklyva, Lodewijk A. A. Brosens, Monica A. J. Marijnissen-van Zanten, Marjolijn J. L. Ligtenberg, Iris D. Nagtegaal
Summary: The prevalence of dMMR in early-onset duodenal, ampullary, and pancreatic carcinomas was explored, with duodenal carcinomas showing the highest prevalence and most being associated with hereditary cancer syndromes. Universal dMMR testing is recommended in all early-onset duodenal, ampullary, and pancreatic carcinomas to determine the underlying hereditary condition.
JOURNAL OF PATHOLOGY CLINICAL RESEARCH
(2022)
Correction
Oncology
Peter H. J. Slootbeek, Iris S. H. Kloots, Minke Smits, Inge M. van Oort, Winald R. Gerritsen, Jack A. Schalken, Marjolijn J. L. Ligtenberg, Katrien Grunberg, Leonie I. Kroeze, Haiko J. Bloemendal, Niven Mehra
BRITISH JOURNAL OF CANCER
(2022)
Article
Oncology
Vera M. Witjes, Joze C. C. Braspenning, Nicoline Hoogerbrugge, Yvonne H. C. M. Smolders, Dorien M. A. Hermkens, Marian J. E. Mourits, Marjolijn J. L. Ligtenberg, Margreet G. E. M. Ausems, Joanne A. de Hullu
Summary: Universal tumor DNA testing in epithelial ovarian cancer patients can serve as an efficient pre-screening tool for hereditary cancer testing and guide treatment choices. However, implementing the Tumor-First workflow requires optimal multidisciplinary collaboration and detailed standardization.
Article
Plant Sciences
Obed G. Gutierrez-Gutierrez, Otilia Rivero-Hernandez, Jose Humberto Vega-Mares, Alicia Melgoza-Castillo
Summary: This study investigated the germination characteristics of 24 grass species and found that several species have the potential for rapid establishment in arid zones, including Eragrostis curvula, Bouteloua curtipendula, Leptochloa dubia, and Digitaria californica. However, invasive species E. lehmanniana and Melinis repens may have other strategies to facilitate their establishment.
BOTANICAL SCIENCES
(2022)
Article
Oncology
Gerben Lassche, Sjoerd van Helvert, Astrid Eijkelenboom, Martijn J. H. Tjan, Erik A. M. Jansen, Patricia H. J. van Cleef, Gerald W. Verhaegh, Eveline J. Kamping, Katrien Grunberg, Adriana C. H. van Engen-van Grunsven, Marjolijn J. L. Ligtenberg, Carla M. L. van Herpen
Summary: This research aimed to assess the prevalence of actionable aberrations in salivary gland cancer (SGC) and identified several new gene fusions. Targets for genetically matched therapies were found in different SGC subtypes. This highlights the potential importance of molecular diagnostics in selecting systemic treatment for SGC.
Article
Oncology
Lisa S. M. Hofste, Maartje J. Geerlings, Daniel von Rhein, Sofie H. Tolmeijer, Marjan M. Weiss, Christian Gilissen, Tom Hofste, Linda M. Garms, Marcel J. R. Janssen, Heidi Rutten, Camiel Rosman, Rachel S. van der Post, Bastiaan R. Klarenbeek, Marjolijn J. L. Ligtenberg
Summary: Ultradeep sequencing-based detection of circulating tumor DNA in preoperative plasma of patients with locally advanced esophageal cancer can predict which patients have a high risk of recurrence after neoadjuvant chemoradiotherapy and surgery.
Article
Oncology
Lisa Elze, Rachel S. van der Post, Janet R. Vos, Arjen R. Mensenkamp, Mirjam S. C. de Hullu, Iris D. Nagtegaal, Nicoline Hoogerbrugge, Richarda M. de Voer, Marjolijn J. L. Ligtenberg
Summary: This study aims to assess whether other tumor types in individuals with Lynch syndrome share characteristics similar to colorectal and endometrial carcinomas. Analysis of the tumor history of 1745 individuals with Lynch syndrome revealed that more than half of the malignant tumors, apart from colorectal and endometrial carcinomas, exhibit microsatellite instability (MSI-H) and mismatch repair-deficiency (dMMR). Therefore, MSI-H/dMMR testing should be conducted for all malignancies in patients with Lynch syndrome when considering therapy with immune checkpoint inhibitors.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Oncology
Peter H. J. Slootbeek, Joanneke K. Overbeek, Marjolijn J. L. Ligtenberg, Nielka P. van Erp, Niven Mehra
Summary: PARP inhibitors have shown great potential in the treatment of metastatic castration-resistant prostate cancer, with superior responses observed in patients with BRCA1 or BRCA2 gene mutations. Combination therapy with androgen receptor signaling inhibitors can prolong progression-free survival in HRRm patients, but has limited efficacy in the non-HRRm subgroup.
Article
Oncology
Henri B. Wolff, Elisabeth M. P. Steeghs, Zakile A. Mfumbilwa, Harry J. M. Groen, Eddy M. Adang, Stefan M. Willems, Katrien Grunberg, Ed Schuuring, Marjolijn J. L. Ligtenberg, Bastiaan B. J. Tops, Veerle M. H. Coupe
Summary: This study evaluates the efficacy of parallel next generation sequencing (NGS)-based testing compared to sequential single-gene-based testing in patients with stage IV nonsquamous non-small-cell lung cancer. The results show that parallel testing is cheaper and more effective than sequential testing, with the ability to detect additional relevant genetic aberrations.
JCO PRECISION ONCOLOGY
(2022)