Article
Biochemistry & Molecular Biology
Katarina Vizarova, Izabela Vajova, Nad'a Krivonakova, Radko Tino, Zdenko Takac, Stefan Vodny, Svetozar Katuscak
Summary: The surface pH is crucial for the quality and longevity of materials and products. Traditional colorimetric pH detection tests lack quantitative values, while this paper presents a method combining impregnation of a tested material with a pH indicator, exposure to a technological process, colorimetric pH measurement, and approximation of pH value.
Article
Surgery
D. M. Felsenreich, M. L. Zach, N. Vock, J. Jedamzik, J. Eichelter, M. Mairinger, L. Gensthaler, L. Nixdorf, P. Richwien, C. Bichler, I. Kristo, F. B. Langer, G. Prager
Summary: This study aims to objectively evaluate reflux and esophagus motility in primary OAGB patients by comparing preoperative and postoperative mid-term outcomes. The results showed a decrease in acid reflux and an increase in non-acid reflux. Gastroscopy also revealed signs of chronic irritation. Follow-up gastroscopies after 5 years may be considered for OAGB patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Aline Schaefer, Philipp Gehwolf, Katrin Kienzl-Wagner, Fergul Cakar-Beck, Heinz Wykypiel
Summary: Linear-stapled gastrojejunostomy is preferred over circular-stapled gastrojejunostomy in reducing the risk of anastomotic ulcers development, while smoking cessation can minimize the risk for anastomotic ulcers and is essential in treatment.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Ophelie Bacoeur-Ouzillou, Julie Perinel, Elise Pelascini, Mourad Abdallah, Gilles Poncet, Arnaud Pasquer, Maud Robert
Summary: This study retrospectively analyzed the management strategies and outcomes of marginal ulcers in a bariatric surgery center. One Anastomosis Gastric Bypass (OAGB) was identified as the only risk factor for recurrence, and conversion to Roux-en-Y Gastric Bypass (RYGB) seemed to be effective for healing.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Brigitte Anderson, Tingting Zhan, Luke Swaszek, Caroline Sanicola, Neil King, Aurora Pryor, Konstantinos Spaniolas, Renee Tholey, Francesco Palazzo, Alec Beekley, Talar Tatarian
Summary: This study evaluated the incidence of marginal ulcers (MUs) after primary and secondary Roux-en-Y Gastric Bypass (RYGB). The results showed that patients who underwent conversion of Sleeve Gastrectomy to RYGB had a higher incidence of MUs compared to those who had primary RYGB or Gastric Banding to RYGB. Furthermore, the time to MU development was significantly shorter in patients who underwent conversion surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Gastroenterology & Hepatology
Azizullah Beran, Mohammad Shaear, Saif Al-Mudares, Ishna Sharma, Reem Matar, Mohammad Al-Haddad, Marita Salame, Ray Portela, Benjamin Clapp, Barham K. Abu Dayyeh, Omar M. Ghanem
Summary: This meta-analysis identified predictors of marginal ulcer (MU) after Roux-en-Y gastric bypass (RYGB) and found that Helicobacter pylori (HP) infection, smoking, and diabetes mellitus were significant predictors. Smoking cessation, optimizing glycemic control, and eradication of HP infection can reduce the risk of MU among high-risk patients.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Review
Medicine, General & Internal
Marita Salame, Noura Jawhar, Amanda Belluzzi, Mohammad Al-Kordi, Andrew C. Storm, Barham K. Abu Dayyeh, Omar M. Ghanem
Summary: Marginal ulcers (MU) are a potential complication following Roux-en-Y gastric bypass (RYGB) surgery, with an average prevalence of 4.6%. Early identification and prompt intervention are crucial to prevent further complications. MU is a complex condition influenced by factors such as smoking, Helicobacter pylori infection, NSAID use, and pouch size. Diagnosis is typically made through endoscopy, and treatment involves modifying risk factors and medical therapy with proton pump inhibitors. Surgical intervention may be necessary for complicated ulcers, while endoscopic procedures and vagotomy may be considered for recurrent or challenging cases.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Patricio Bernardo Lynn, Sarah Elizabeth Pivo, Mohamed El Zaeedi, Manish Parikh, John Kenneth Saunders
Summary: Stricture of the gastrojejunostomy is a potential complication following laparoscopic Roux-en-Y gastric bypass, requiring surgical intervention for repair.
Article
Gastroenterology & Hepatology
Christopher B. Crawford, Leslie M. Schuh, Margaret M. Inman
Summary: This study compares two surgical methods for repairing ulcer perforations after Roux-en-Y gastric bypass (RYGB) surgery. The results show that revision gastrojejunostomy is a more effective treatment option for patients with ulcer recurrence, with comparable short-term morbidity compared to suturing with or without an omental patch.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Medicine, General & Internal
Lukas Horvath, Patricia Hagmann, Emanuel Burri, Marcel Kraft
Summary: This study confirmed the common occurrence of Laryngopharyngeal reflux and demonstrated the reliability of oropharyngeal pH-monitoring in assessing LPR, although the pH graphs need to be precisely interpreted in conjunction with other validated diagnostic tests.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Seyed Nooredin Daryabari, Seyed Adel Maleknia, Faridadin Ebrahimi Meimand, Abdolreza Pazouki, Mohammad Kermansaravi
Summary: One anastomosis gastric bypass is a widely accepted bariatric procedure, but a rare but serious complication is the perforation of marginal ulcer, with a 0.5-1% incidence rate, which may require conversion to RYGB for definitive therapy in complex or refractory ulcer cases.
Article
Endocrinology & Metabolism
Xiang Gao, Song Dai, Guohui Wang, Weizheng Li, Zhi Song, Zhihong Su, Shaihong Zhu, Liyong Zhu, Pengzhou Li
Summary: This study assessed the 6-year outcomes of Chinese patients with T2D and a BMI < 35 kg/m2 who underwent RYGB with gastric pouches of different sizes. The results showed that a small gastric pouch resulted in better weight loss and glycemic control, and high preoperative BMI and a small gastric pouch were associated with better T2D remission rates.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Betul Danisman, Betul Cicek, Serkan Yildirim, Ismail Bolat, Deniz Kantar, Kirill S. Golokhvast, Dragana Nikitovic, Aristidis Tsatsakis, Ali Taghizadehghalehjoughi
Summary: This study aimed to investigate the impact of carnosic acid (CA) on indomethacin (IND)-induced gastric ulceration. The results showed that CA pretreatment attenuated both gross morphological lesions and histopathological alterations induced by IND, and it achieved gastroprotective effects by reducing oxidative stress and suppressing inflammation.
Article
Surgery
Adam Di Palma, Benjamin Liu, Azusa Maeda, Mehran Anvari, Timothy Jackson, Allan Okrainec
Summary: Smoking history, use of immunosuppressive medication, and preoperative NSAID use were significantly associated with an increased risk of developing recalcitrant marginal ulcers. Patients undergoing revisional surgery reported symptom resolution in only 36% of cases, with 57% developing recurrent ulcers. Additional evidence is needed to guide perioperative management of bariatric patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Surgery
Briana Sowers, Benjamin L. Reed, Nova Szoka, Lawrence E. Tabone, Salim Abunnaja
Summary: This article presents cases of marginal ulcers (MUs) in patients who have undergone Roux-en-Y gastric bypass (RYGB) surgery and discusses the different treatment strategies. MUs have a wide range of complex clinical presentations, and managing them requires familiarity with their anatomic variances and operative skill to effect resolution.
Article
Microbiology
Jorik M. van Rijn, Jens Eriksson, Jana Gruttner, Magnus Sundbom, Dominic-Luc Webb, Per M. Hellstrom, Staffan G. Svard, Mikael E. Sellin
Summary: Understanding the dynamic interactions between individual microbes and host cells is crucial for infectious disease research. A new method for live-cell imaging of microbial infection dynamics on human intestinal epithelial cell layers has been developed, providing insights into the behavior of Salmonella and Giardia pathogens.
Article
Surgery
Martin L. Skogar, Erik Stenberg, Magnus Sundbom
Summary: The aim of this study was to explore whether the weekday of surgery affects the 30-day complication risks after primary Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG). The study found that there was no significant increased risk of overall complications, severe complications, or readmission rates by weekday of surgery, except for a lower readmission rate in patients operated on Tuesdays.
Article
Surgery
Martin L. Skogar, Magnus Sundbom
Summary: This study investigated the association between NSAID exposure and peptic ulcers after laparoscopic RYGB and SG surgeries. The results showed that long-term NSAID use (>=30 days) after RYGB was a significant risk factor for the development of peptic ulcers, while no association was found between NSAID exposure and peptic ulcers after SG.
SURGERY FOR OBESITY AND RELATED DISEASES
(2022)
Article
Surgery
Erik Stenberg, Henrik Larsson, Richard Marsk, Yang Cao, Magnus Sundbom, Erik Naslund
Summary: This study aimed to assess the short-term and long-term outcomes of metabolic and bariatric surgery in patients with attention deficit hyperactivity disorder (ADHD). The results showed that patients with ADHD treated pharmacologically for ADHD experienced similar weight loss and remission of obesity-related diseases compared to patients without ADHD. However, they reported a lower health-related quality of life and had an increased risk of substance abuse and self-harm.
SURGERY FOR OBESITY AND RELATED DISEASES
(2023)
Article
Surgery
Anna Laurenius, Magnus Sundbom, Johan Ottosson, Erik Näslund, Erik Stenberg
Summary: Obesity is associated with an increased risk of kidney stones, especially after metabolic and bariatric surgery. However, there is a lack of reports on baseline risk factors and larger population-based cohorts. This study aimed to evaluate the incidence and risk factors for postoperative kidney stones after bariatric surgery by comparing them to a matched control group from the normal population.
Article
Surgery
Magnus Sundbom, Eladio Cabrera, Rickard Nyman, Charlotte Ebeling Barbier, Ulf Johnson, Mikael Ljungdahl
Summary: This study compared percutaneous endoscopic gastrostomy (PEG) with radiologically inserted gastrostomy (RIG) in adults and found that PEG had shorter operative time, lower rate of adverse events, and lower 30-day mortality, making it the recommended primary procedure. However, RIG is also a valid alternative method.
SCANDINAVIAN JOURNAL OF SURGERY
(2023)
Article
Microbiology
Jana Gruttner, Jorik M. van Rijn, Petra Geiser, Alexandra Florbrant, Dominic-Luc Webb, Per M. Hellstrom, Magnus Sundbom, Mikael E. Sellin, Staffan G. Svard
Summary: Giardia intestinalis is a parasite that infects the upper small intestine of mammals. It can cause diarrhoeal disease in humans, but many infections do not cause symptoms. The molecular mechanisms behind these different outcomes are still unclear.
Article
Surgery
Filip Moller, Jakob Hedberg, Martin Skogar, Magnus Sundbom
Summary: In super obesity, biliopancreatic diversion with duodenal switch (BPD/DS) is advocated by some surgeons as a more effective procedure compared to Roux-en-Y gastric bypass (RYGB). However, there is limited evidence on long-term outcomes beyond 10 years. This study compared the long-term outcome of BPD/DS and RYGB in patients with super obesity and found that BPD/DS resulted in superior weight loss, metabolic control, and BAROS score, but with more adverse events.
Editorial Material
Respiratory System
Magnus Sundbom
JOURNAL OF THORACIC DISEASE
(2023)
Article
Endocrinology & Metabolism
Eva Randell, Petros Katsogiannos, Janeth Leksell, Jan W. W. Eriksson, Magnus Sundbom, Maria Svedbo Engstrom
Summary: This qualitative study examined how adults with previous type 2 diabetes perceived different sources of support two years after bariatric surgery. The findings revealed that support needs changed over time and that long-term professional and day-to-day support from family and other networks were essential and complementary.
Article
Endocrinology & Metabolism
Giovanni Fanni, Christakis Kagios, Erika Roman, Magnus Sundbom, Johan Wikstrom, Sven Haller, Jan W. Eriksson
Summary: This study aimed to investigate the effect of Roux-en-Y gastric bypass (RYGB) on brain connectivity, and found that RYGB can alter the connectivity of neural pathways related to reward, inhibitory control, and energy homeostasis. These changes are associated with alterations in hypoglycemic responses and may contribute to the glucose metabolic outcomes of RYGB.
Review
Endocrinology & Metabolism
Magnus Sundbom, Ingmar Naslund, Johan Ottosson, Erik Stenberg, Erik Naslund
Summary: The Scandinavian Obesity Surgery Registry (SOReg) is a high-quality database used to monitor the results of bariatric surgery and conduct research. Swedish bariatric surgery has low mortality rates compared to other countries, and gastric bypass surgery significantly improves obesity-related diseases and quality of life while reducing the risk of cardiac failure and major adverse cardiovascular events. Additionally, the database reveals a correlation between low socioeconomic status and reduced opportunities for surgery and inferior outcomes.
Meeting Abstract
Gastroenterology & Hepatology
Lars Johansson, Magnus Sundbom, Edvin Johansson, Joel Kullberg
JOURNAL OF HEPATOLOGY
(2023)
Meeting Abstract
Gastroenterology & Hepatology
Khalid Elias, Dominic-Luc Webb, Hetzel O. Diaz Tartera, Per M. Hellstrom, Magnus Sundbom
Article
Surgery
Johanna Fall, Magnus Sundbom, Erik Stenberg
Summary: This study examines the impact of summer closure on the incidence of serious postoperative complications in bariatric surgery using a large cohort. The results indicate that summer closure increases the risk of serious complications in gastric bypass surgery, while no statistically significant association was found in sleeve gastrectomy surgery or overall complication rate.
LANGENBECKS ARCHIVES OF SURGERY
(2022)