Article
Surgery
Shinwa Tanaka, Tetsuya Yoshizaki, Yoshinobu Yamamoto, Takayuki Ose, Tsukasa Ishida, Yasuaki Kitamura, Daisuke Obata, Mineo Iwatate, Mikio Fujita, Atsushi Ikeda, Ryusuke Ariyoshi, Fumiaki Kawara, Hirofumi Abe, Toshitatsu Takao, Yoshinori Morita, Yasushi Sano, Eiji Umegaki, Hogara Nishisaki, Takashi Toyonaga, Yuzo Kodama
Summary: A risk-scoring model was developed and validated for predicting the technical difficulty of ESD for RGC after DG, which can contribute to a safer and more reliable performance of the procedure.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Medicine, General & Internal
Shan-Shan Xu, Ning-Li Chai, Xiao-Wei Tang, En-Qiang Linghu, Sha-Sha Wang, Bao Li
Summary: This study analyzed the characteristics, risk factors, treatment, and follow-up outcomes of patients with metachronous gastric neoplasms (MGN) following curative endoscopic submucosal dissection (ESD). It found that initial multiplicity was the sole independent risk factor of MGN, and patients with MGN had significantly lower disease-specific survival rate compared to those without MGN. Regular and long-term surveillance endoscopy may be beneficial for patients with initial multiple neoplasms.
CHINESE MEDICAL JOURNAL
(2021)
Article
Gastroenterology & Hepatology
Andreia Rei, Raquel Ortigao, Mariana Pais, Luis P. Afonso, Pedro Pimentel-Nunes, Mario Dinis-Ribeiro, Diogo Libanio
Summary: Surveillance after gastric endoscopic submucosal dissection (ESD) is recommended for all patients to monitor the risk of metachronous gastric lesions (MGLs). A prediction score, derived from clinical predictors, has been developed and validated to estimate MGL risk after ESD for early neoplastic gastric lesions, providing an individualized and cost-saving approach.
Article
Medicine, General & Internal
Mai Murakami, Takuto Hikichi, Jun Nakamura, Minami Hashimoto, Tsunetaka Kato, Ryoichiro Kobashi, Takumi Yanagita, Rei Suzuki, Mitsuru Sugimoto, Yuki Sato, Hiroki Irie, Mika Takasumi, Tadayuki Takagi, Yuko Hashimoto, Masao Kobayakawa, Hiromasa Ohira
Summary: ESD is an effective and safe treatment for patients with early gastric cancers in the remnant stomach, even when suture line involvement is present.
Article
Medicine, General & Internal
Choong-Kyun Noh, Eunyoung Lee, Bumhee Park, Sun Gyo Lim, Sung Jae Shin, Kee Myung Lee, Gil Ho Lee
Summary: This study investigated the long-term effect of Helicobacter pylori eradication on the prevention of metachronous gastric neoplasm after endoscopic submucosal dissection (ESD) of gastric adenoma. The results showed that eradication of H. pylori did not increase the risk of metachronous gastric neoplasm after ESD.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Yi Liu, Zhihao Chen, Hong Zhou, Yingtai Chen, Lizhou Dou, Yueming Zhang, Yong Liu, Shun He, Dongbing Zhao, Guiqi Wang
Summary: This study compared the effectiveness of endoscopic submucosal dissection (ESD) and radical surgery for early gastric cancer in the remnant stomach or gastric tube. The results showed that ESD had shorter operation time, shorter post-operative hospital stay, lower incidence of post-operative complications, and better quality of life compared to surgery. There was no significant difference in overall survival or disease-free survival between the two groups.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Gastroenterology & Hepatology
Zhao Wu Meng, Kirles Bishay, Marcus Vaska, Yibing Ruan, Mohammad A. Al-Haddad, Sherif E. Elhanafi, Bashar J. Qumseya, Paul J. Belletrutti, Richdeep Gill, Estifanos Debru, Steven J. Heitman, Darren R. Brenner, Nauzer Forbes
Summary: For metachronous EGC, ESD or surgery is preferred over EMR depending on local expertise and patient preferences, largely due to a higher risk of incomplete resection with EMR.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Surgery
Jinju Choi, Sara Kim, Hyunsoo Chung, Seong-Ho Kong, Soo-Jeong Cho, Do-Joong Park, Hyuk-Joon Lee, Sang Gyun Kim, Han-Kwang Yang
Summary: This study evaluated the occurrence of metachronous gastric neoplasms (mGNs) in the residual stomach after pylorus-preserving gastrectomy (PPG). The incidence of mGNs was low in the PPG group and risk factors for mGNs in the ESD group included synchronous neoplasms and moderate-to-severe intestinal metaplasia. Longer follow-up studies on longer antral cuffs are recommended.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Pinghu Sun, Tuo Zheng, Chunjiu Hu, Tengjiao Gao, Xiaoyun Ding
Summary: Compared with ESD, ESD-ME achieved a higher histological complete resection rate, had a similar rate of complications, and required a similar procedure time for rectal NETs < 16 mm in diameter without metastasis.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Oncology
Haruhisa Suzuki, Satoru Nonaka, Iruru Maetani, Takahisa Matsuda, Seiichiro Abe, Shigetaka Yoshinaga, Ichiro Oda, Yukinori Yamagata, Takaki Yoshikawa, Yutaka Saito
Summary: This study explores the features of patients with metachronous gastric cancer (MGC) with possible lymph node metastasis (LNM) after endoscopic submucosal dissection (ESD) and Helicobacter pylori (H. pylori) eradication. It is found that MGCs are more common in the posterior wall of the stomach and lower body mass index (BMI) may be associated with the development of MGCs with possible LNM.
Article
Oncology
Ji Eun Na, Hyuk Lee, Yang Won Min, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Kyoung-Mee Kim, Jae J. Kim
Summary: Primary endoscopic submucosal dissection is clinically feasible and oncologically safe for cT1bN0M0 gastric cancer, with a high curative resection rate. It can potentially eliminate unnecessary surgery and further management can be based on post-procedure pathology results.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2021)
Article
Gastroenterology & Hepatology
Mitsuaki Ishioka, Toshiyuki Yoshio, Yuji Miyamoto, Ken Namikawa, Yoshitaka Tokai, Shoichi Yoshimizu, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiaki Hirasawa, Tomohiro Tsuchida, Junko Fujisaki
Summary: This study investigated the incidence and characteristics of metachronous cancer after endoscopic submucosal dissection for undifferentiated-type gastric cancer, finding a correlation between Helicobacter pylori infection and metachronous cancer development. The curative resection rate after ESD for undifferentiated-type cancer was significantly lower. Surveillance should be conducted more carefully after ESD for undifferentiated-type cancer, especially in H. pylori-infected patients.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Surgery
Jeong Ho Song, Sejin Lee, Sung Hyun Park, Anastasios Kottikias, Aleisa Abdulmohsen, Nasser Alrashidi, Minah Cho, Yoo Min Kim, Hyoung-Il Kim, Woo Jin Hyung
Summary: This study suggests that patients with early gastric cancer who meet the surgical indications can be treated with endoscopic submucosal dissection. The location of the tumor, as well as its size and histological features, are key factors in determining whether curative resection can be achieved with ESD.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Shinichiro Makimoto, Yutaka Mushiake, Tomoya Takami, Hiroshi Shintani, Naoki Kataoka, Tomoyuki Yamaguchi, Shoji Oura
Summary: The aim of this study was to clarify the risk factors for lymph node metastasis and local residual cancer after noncurative endoscopic submucosal dissection (ESD) for early gastric cancer, and to provide recommendations for additional treatment. The results showed that additional gastrectomy with lymph node dissection should be considered for patients with lymphovascular invasion and/or undifferentiated type, while careful follow-ups without additional surgery might be acceptable for patients with advanced age, severe comorbidity, or no lymphovascular invasion.
Article
Gastroenterology & Hepatology
Seitaro Shimada, Yohei Yabuuchi, Noboru Kawata, Yuki Maeda, Masao Yoshida, Yoichi Yamamoto, Tatsunori Minamide, Kohei Shigeta, Kazunori Takada, Yoshihiro Kishida, Sayo Ito, Kenichiro Imai, Kinichi Hotta, Hirotoshi Ishiwatari, Hiroyuki Matsubayashi, Hiroyuki Ono
Summary: This study aimed to elucidate the endoscopic causes and characteristics of missed gastric cancers (MGCs) after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC). The results showed that the endoscopic causes of MGCs included perceptual errors, exposure errors, sampling errors, and inadequate preparation. Logistic regression analysis revealed the risk factors for perceptual errors and the sites of exposure errors.
GASTROINTESTINAL ENDOSCOPY
(2023)
Editorial Material
Gastroenterology & Hepatology
Soo-Jeong Cho
CLINICAL ENDOSCOPY
(2022)
Letter
Allergy
Hanjae Lee, Soo Ick Cho, Min-Suk Yang, Soo-Jeong Cho, Dong Hun Lee
Editorial Material
Gastroenterology & Hepatology
Kwang Hyun Chung, Soo-Jeong Cho
CLINICAL ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Hyun Deok Lee, Eunwoo Lee, Sang Gyun Kim, Cheol Min Shin, Jun Chul Park, Kee Don Choi, Seokyung Hahn, Soo-Jeong Cho
Summary: This study evaluated the efficacy of fibrin glue in preventing postendoscopic submucosal dissection (ESD) bleeding in high-risk patients. The results showed that fibrin glue did not have a preventive effect on overall post-ESD bleeding, but it had a potential sealing effect during the acute period.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Oncology
Yun Suk Na, Sang Gyun Kim, Soo-Jeong Cho
Summary: High OLGA and OLGIM stages are independent risk factors for metachronous gastric cancer, with the OLGIM staging system being a better predictor. Patients with OLGIM stages 0 similar to II may benefit more from Helicobacter pylori eradication.
Article
Gastroenterology & Hepatology
Jue Lie Kim, Sang Gyun Kim, Enerelt Natsagdorj, Hyunsoo Chung, Soo-Jeong Cho
Summary: This study evaluated the epigenetic and genetic expression changes of multiple Rho GTPases in Helicobacter pylori-related gastric carcinogenesis. It found that DOCK180 and ELMO1 had higher DNA methylation and expression levels in gastric cancer, while RhoA and Rac1 had lower levels. CDC42 had the same expression pattern as DOCK180 and ELMO1 without DNA methylation. The study also showed that H. pylori eradication could improve the epigenetic field of gastric carcinogenesis.
Article
Oncology
Young Soo Park, Myeong-Cherl Kook, Baek-hui Kim, Hye Seung Lee, Dong-Wook Kang, Mi-Jin Gu, Ok Ran Shin, Younghee Choi, Wonae Lee, Hyunki Kim, In Hye Song, Kyoung-Mee Kim, Hee Sung Kim, Guhyun Kang, Do Youn Park, So -Young Jin, Joon Mee Kim, Yoon Jung Choi, Hee Kyung Chang, Soomin Ahn, Mee Soo Chang, Song-Hee Han, Yoonjin Kwak, An Na Seo, Sung Hak Lee, Mee-Yon Cho
Summary: This edition is composed of standard data elements and conditional data elements. Standard data elements contain basic pathological findings and necessary items to predict the prognosis of GC patients, while conditional data elements include additional diagnostic and prognostic factors relevant to adjuvant therapy, such as molecular biomarkers. They are designed to allow pathologists to selectively choose appropriate items based on their institution's environment. The standardized pathology report aims to improve GC diagnosis and facilitate large-scale research.
JOURNAL OF GASTRIC CANCER
(2023)
Review
Pathology
Young Soo Park, Myeong-Cherl Kook, Baek-hui Kim, Hye Seung Lee, Dong-Wook Kang, Mi-Jin Gu, Ok Ran Shin, Younghee Choi, Wonae Lee, Hyunki Kim, In Hye Song, Kyoung-Mee Kim, Hee Sung Kim, Guhyun Kang, Do Youn Park, So -Young Jin, Joon Mee Kim, Yoon Jung Choi, Hee Kyung Chang, Soomin Ahn, Mee Soo Chang, Song-Hee Han, Yoonjin Kwak, An Na Seo, Sung Hak Lee, Mee-Yon Cho
Summary: The first edition of 'A Standardized Pathology Report for Gastric Cancer' was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago. This second edition consists of standard data elements and conditional data elements, including basic pathologic findings and items necessary for predicting the prognosis of GC patients. Other factors relevant to adjuvant therapy are classified as conditional data elements. The standardized pathology report will be helpful for GC diagnosis and facilitate collaborative studies.
JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE
(2023)
Article
Oncology
Drolaiz H. W. Liu, Young-Woo Kim, Nina Sefcovicova, Jon P. Laye, Lindsay C. Hewitt, Andrew F. Irvine, Vincent Vromen, Yannick Janssen, Naser Davarzani, Gregorio E. Fazzi, Shahab Jolani, Veerle Melotte, Derek R. Magee, Myeong-Cherl Kook, Hyunki Kim, Rupert Langer, Jae-Ho Cheong, Heike I. Grabsch
Summary: This study suggests that the quantification of TIL density in routine HE stained tissue sections can be a novel and clinically useful biomarker for identifying stage II-III gastric cancer patients who would benefit from adjuvant chemotherapy. Further validation through prospective studies is needed.
BRITISH JOURNAL OF CANCER
(2023)
Article
Oncology
Bokyung Kim, Kyungdo Han, Hyunsoo Chung, Sang Gyun Kim, Soo-Jeong Cho
Summary: This study found that smoking cessation and alcohol abstinence are associated with reduced risk of developing depression in patients with gastric cancer who undergo surgery, while starting regular physical activity is not associated with risk of depression.
Article
Surgery
Soo Yeong Lim, Hong Man Yoon, Myeong-Cherl Kook, Jin Il Jang, Peter T. C. So, Jeon Woong Kang, Hyung Min Kim
Summary: A machine-learning-based spectro-histological model was developed to accurately differentiate different layers of gastric tissue using autofluorescence spectra. The model achieved high prediction accuracy for mucosa, submucosa, and muscularis propria, with scores of 92.0%, 90.1%, and 91.4% respectively. The model was tested on both sliced and block tissue samples using a fast fluorescence imaging scanner.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Medicine, General & Internal
Jae Chang Jun, Sang Hyub Lee, Han Myung Lee, Sang Gyun Kim, Hyunsoo Chung, Joo Seong Kim, Namyoung Park, Jin Ho Choi, Yoonjin Kwak, Soo-Jeong Cho
Summary: This study compared the diagnostic performance of SurePath (TM) liquid-based cytology (LBC) and conventional smear (CS) cytology in endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) samples of upper gastrointestinal lesions. The results showed that LBC was not inferior to CS in diagnostic accuracy and had a shorter sample preparation time and better field of view.
Article
Surgery
Seunghan Lee, Sang Gyun Kim, Soo-Jeong Cho
Summary: This study investigated the suitability of the eCura system for determining the need for radical surgery after non-curative endoscopic submucosal dissection (ESD) for early gastric cancer (EGC). The results showed that follow-up without additional surgery after non-curative ESD can be a reasonable option for low-risk and even intermediate-risk patients according to the eCura system, but surgery is warranted for high-risk patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Medicine, General & Internal
Seung Joo Kang, Jae Gyu Kim, Hee Seok Moon, Myeong-Cherl Kook, Jong Yeul Lee, Chang Seok Bang, Chung Hyun Tae, Eun Jeong Gong, Su Youn Nam, Hyun Jung Kim
Summary: Gastritis is a common disease characterized by inflammation of the gastric mucosa, with various classification systems available. Recent emphasis has been placed on H. pylori gastritis due to its association with gastric cancer development and the potential for prevention through eradication. Although Korea has the highest incidence rate of gastric cancer globally, there are currently no clinical guidelines for atrophic gastritis and intestinal metaplasia. To address this, the Korean College of Helicobacter and Upper Gastrointestinal Research developed evidence-based guidelines through systematic review and made recommendations for key questions. This guideline will need periodic revision as new evidence emerges.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Medicine, General & Internal
Bokyung Kim, Jin-Hyung Jung, Kyungdo Han, Seungkyung Kang, Eunwoo Lee, Hyunsoo Chung, Sang Gyun Kim, Soo-Jeong Cho
Summary: This study aimed to investigate the effect of histamine-2 receptor antagonist (H2RA) and proton pump inhibitor (PPI) use on the positivity rate and clinical outcomes of COVID-19. The results showed that H2RA and PPI use was associated with a decreased risk for SARS-CoV-2 infection, but did not affect clinical outcomes. The protective effect of H2RA and PPI was not significant in patients with comorbidities such as diabetes, hypertension, and dyslipidemia.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)