Article
Surgery
Hyo-Joon Yang, Moon Kyung Joo, Jae Myung Park, Ji Yong Ahn, Jae-Young Jang, Joo Hyun Lim, Su Youn Nam, Jie-Hyun Kim, Byung-Hoon Min, Wan-Sik Lee, Bong Eun Lee, Woon Geon Shin, Hang Lak Lee, Tae-Geun Gweon, Moo In Park, Jeongmin Choi, Chung Hyun Tae, Young-Il Kim, Keun Won Ryu, Il Ju Choi
Summary: The study developed a six-score prediction model to help predict the likelihood of curative ESD for undifferentiated-type EGC, based on factors such as tumor size and location. This model showed good performance in both the development and validation cohorts, providing valuable information for treatment decision-making.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Jiyoung Yoon, Seung-Yeon Yoo, Young Soo Park, Kee Don Choi, Beom Su Kim, Moon-Won Yoo, In Seob Lee, Jeong Hwan Yook, Ga Hee Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
Summary: This study investigated the prevalence and risk factors of lymph node metastasis (LNM) in undifferentiated early gastric cancer (UD-EGC) cases meeting the expanded indication for endoscopic submucosal dissection (ESD). The results showed that the risk of LNM is higher than expected when using the current expanded indication for UD-EGC. Histological evaluation could provide useful clues for reducing the risk of LNM.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Gastroenterology & Hepatology
Mitsuaki Ishioka, Toshiyuki Yoshio, Yuji Miyamoto, Ken Namikawa, Yoshitaka Tokai, Shoichi Yoshimizu, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiaki Hirasawa, Tomohiro Tsuchida, Junko Fujisaki
Summary: This study investigated the incidence and characteristics of metachronous cancer after endoscopic submucosal dissection for undifferentiated-type gastric cancer, finding a correlation between Helicobacter pylori infection and metachronous cancer development. The curative resection rate after ESD for undifferentiated-type cancer was significantly lower. Surveillance should be conducted more carefully after ESD for undifferentiated-type cancer, especially in H. pylori-infected patients.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Medicine, General & Internal
Dae-Gon Ryu, Su-Jin Kim, Cheol-Woong Choi, Su-Bum Park, Hyeong-Seok Nam, Si-Hak Lee, Sun-Hwi Hwang
Summary: Endoscopic submucosal dissection (ESD) is the preferred treatment for early gastric cancer (EGC) with low risk of lymph node metastasis. Predicting the risk of local recurrence after ESD is crucial for management and prevention. Factors associated with a higher risk of local recurrence include lesion size >= 15 mm, incomplete histologic resection, undifferentiated adenocarcinoma, scar, and the absence of erythema of the surface. Regular endoscopic surveillance is important to predict local recurrence, especially in patients with larger lesions, incomplete histologic resection, surface changes of scars, and no surface erythema.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Surgery
Hyo-Joon Yang, Jie-Hyun Kim, Na Won Kim, Il Ju Choi
Summary: Studies comparing the long-term outcomes of endoscopic submucosal dissection (ESD) and surgery for undifferentiated-type early gastric cancer (UD EGC) found that ESD had inferior disease-free survival (DFS) and higher recurrence rates compared to surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Jeong Ho Song, Sejin Lee, Sung Hyun Park, Anastasios Kottikias, Aleisa Abdulmohsen, Nasser Alrashidi, Minah Cho, Yoo Min Kim, Hyoung-Il Kim, Woo Jin Hyung
Summary: This study suggests that patients with early gastric cancer who meet the surgical indications can be treated with endoscopic submucosal dissection. The location of the tumor, as well as its size and histological features, are key factors in determining whether curative resection can be achieved with ESD.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Medicine, General & Internal
Yu-Lan Gao, Yue-han Zhang, Meng Cao
Summary: This study retrospectively analyzed the preoperative endoscopic evaluation in endoscopic submucosal dissection (ESD) for early gastric cancer and precancerous lesions. Accurate preoperative assessment of lesion type, extent, and depth of invasion is helpful in improving the complete resection rate and reducing the risk of additional surgery in ESD.
Article
Gastroenterology & Hepatology
Waku Hatta, Yosuke Tsuji, Toshiyuki Yoshio, Naomi Kakushima, Shu Hoteya, Hisashi Doyama, Yasuaki Nagami, Takuto Hikichi, Masakuni Kobayashi, Yoshinori Morita, Tetsuya Sumiyoshi, Mikitaka Iguchi, Hideomi Tomida, Takuya Inoue, Tomoyuki Koike, Tatsuya Mikami, Kenkei Hasatani, Jun Nishikawa, Tomoaki Matsumura, Hiroko Nebiki, Dai Nakamatsu, Ken Ohnita, Haruhisa Suzuki, Hiroya Ueyama, Yoshito Hayashi, Mitsushige Sugimoto, Shinjiro Yamaguchi, Tomoki Michida, Tomoyuki Yada, Yoshiro Asahina, Toshiaki Narasaka, Shiko Kuribasyashi, Shu Kiyotoki, Katsuhiro Mabe, Tomohiro Nakamura, Naoki Nakaya, Mitsuhiro Fujishiro, Atsushi Masamune
Summary: A prediction model for bleeding after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) was developed and externally validated, showing moderately good discrimination and good calibration.
Article
Oncology
Meng Qian, Yuan Sheng, Min Wu, Song Wang, Kaiguang Zhang
Summary: This retrospective case-control study compared the clinical outcomes of endoscopic submucosal dissection (ESD) and surgical resection for early gastric cancer (EGC). After propensity score-matching, the ESD group showed comparable overall survival, disease-specific survival, and recurrence-free survival with the surgery group. The ESD group also had less blood loss, fewer adverse events, lower hospital cost, and a shorter operative time and hospital duration. Therefore, ESD can be considered as a first-line treatment for EGC.
Article
Oncology
Ji Yong Ahn, Young- Kim, Woon Geon Shin, Hyo-Joon Yang, Su Youn Nam, Byung-Hoon Min, Jae-Young Jang, Joo Hyun Lim, Jie-Hyun Kim, Wan Sik Lee, Bong Eun Lee, Moon Kyung Joo, Jae Myung Park, Hang Lak Lee, Tae- Geun Gweon, Moo In Park, Jeongmin Choi, Chung Hyun Tae, Young-Woo Kim, Boram Park, I. I. Ju Choi
Summary: Comparing outcomes of ESD and surgery for UD EGC within expanded indication, the study found that ESD shows comparable results to surgery, but appropriate patient selection is necessary due to the risk of lymph node metastasis.
Article
Medicine, General & Internal
Yinuo Zhao, Huogen Wang, Yanyan Fan, Chaohui Jin, Qinwei Xu, Jiyong Jing, Tianqiao Zhang, Xuedong Zhang, Wanyuan Chen
Summary: In this study, we developed a software pipeline named "Pathology Helper" to assist in the construction of high-quality mucosal recovery maps, reducing the workload of endoscopists and pathologists, while accelerating their ability to diagnose EGC.
FRONTIERS IN MEDICINE
(2022)
Review
Oncology
Zhi Zheng, Jie Yin, Xiao-Ye Liu, Xiao-Sheng Yan, Rui Xu, Meng-Yi Li, Jun Cai, Guang-Yong Chen, Jun Zhang, Zhong-Tao Zhang
Summary: The advancement of endoscopic treatment technology has facilitated minimally invasive treatment for EGC, but challenges remain in managing non-curative resection patients, improving clinical staging accuracy, and selecting appropriate treatment methods.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY
(2021)
Article
Gastroenterology & Hepatology
Gil Ho Lee, Eunyoung Lee, Bumhee Park, Jin Roh, Sun Gyo Lim, Sung Jae Shin, Kee Myung Lee, Choong-Kyun Noh
Summary: By comparing the clinical outcomes of ESD and surgery in patients with UD intramucosal EGC, it was found that the ESD group had a shorter hospital stay, but inferior RFS and local recurrence were observed.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Medicine, General & Internal
Mai Murakami, Takuto Hikichi, Jun Nakamura, Minami Hashimoto, Tsunetaka Kato, Ryoichiro Kobashi, Takumi Yanagita, Rei Suzuki, Mitsuru Sugimoto, Yuki Sato, Hiroki Irie, Mika Takasumi, Tadayuki Takagi, Yuko Hashimoto, Masao Kobayakawa, Hiromasa Ohira
Summary: ESD is an effective and safe treatment for patients with early gastric cancers in the remnant stomach, even when suture line involvement is present.
Article
Oncology
Ji Eun Na, Hyuk Lee, Yang Won Min, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Kyoung-Mee Kim, Jae J. Kim
Summary: Primary endoscopic submucosal dissection is clinically feasible and oncologically safe for cT1bN0M0 gastric cancer, with a high curative resection rate. It can potentially eliminate unnecessary surgery and further management can be based on post-procedure pathology results.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2021)
Article
Gastroenterology & Hepatology
Sun Min Lee, Nayoung Kim, Yong Hwan Kwon, Ryoung Hee Nam, Jung Mogg Kim, Jong Youn Park, Yeon Suk Lee, Dong Ho Lee
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2018)
Review
Multidisciplinary Sciences
Hyunsuk Frank Roh, Seung Hyuk Nam, Jung Mogg Kim
Article
Gastroenterology & Hepatology
Jung W. Lee, Nayoung Kim, Ryoung H. Nam, Sun M. Lee, Yong H. Kwon, So D. Sohn, Jung M. Kim, Dong H. Lee, Hyun C. Jung
Article
Gastroenterology & Hepatology
Jung Won Lee, Nayoung Kim, Ryoung Hee Nam, Sun Min Lee, Choi Soo In, Jung Mogg Kim, Dong Ho Lee
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2019)
Article
Immunology
Jong Ik Jeon, Su Hyuk Ko, Jung Mogg Kim
INFECTION AND IMMUNITY
(2019)
Article
Gastroenterology & Hepatology
Su Hyuk Ko, Jong Ik Jeon, Hyun Ae Woo, Jung Mogg Kim
WORLD JOURNAL OF GASTROENTEROLOGY
(2020)
Article
Gastroenterology & Hepatology
Eun Jeong Gong, Ji Yong Ahn, Da Kyung Jung, Sun Mi Lee, Gyu Young Pih, Ga Hee Kim, Hee Kyong Na, Jeong Hoon Lee, Hwoon-Yong Jung, Jung Mogg Kim
Article
Medicine, General & Internal
Eun Jeong Gong, Ji Yong Ahn, Jung Mogg Kim, Sun Mi Lee, Hee Kyong Na, Jeong Hoon Lee, Kee Wook Jung, Kee Don Choi, Do Hoon Kim, Ho June Song, Gin Hyug Lee, So Won Kim, Hwoon-Yong Jung
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Immunology
Jeong Rae Yoo, Jae-Yong Kim, Sang Taek Heo, Jihye Kim, Hyeong-Jun Park, Joo-Yeon Lee, Hee-Young Lim, Woo-Jung Park, Nam-Hyuk Cho, Jung Mogg Kim, Jae-Hwan Nam, Keun Hwa Lee
Summary: The titers of neutralizing antibodies to SFTSV were found to be higher in survivors and healthy residents in endemic areas, providing important protective immunity against the virus. In contrast, non-surviving patients had lower titers of neutralizing antibodies, suggesting a potential link to higher mortality rates.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Immunology
Jeong Rae Yoo, Tae-Jin Kim, Sang Taek Heo, Kyung-Ah Hwang, Hyunjoo Oh, TaeHong Ha, Hye Kyung Ko, Seungjae Baek, Ju Eun Kim, Jun Hyeong Kim, Jiin Lee, Min Ji Kang, Mi Soo Yoo, Jung Mogg Kim, Kyung-Mi Lee, Keun Hwa Lee
Summary: In this study, it was found that various biomarkers and inflammatory factors were higher in patients with fatal SFTS than in those with nonfatal disease during the initial clinical course. Additionally, IL-6 and IL-10 levels were strongly correlated with outcomes in SFTSV-infected patients.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Gastroenterology & Hepatology
Yoon Jin Choi, Yong Chan Lee, Jung Mogg Kim, Jin Il Kim, Jeong Seop Moon, Yun Jeong Lim, Gwang Ho Baik, Byoung Kwan Son, Hang Lak Lee, Kyoung Oh Kim, Nayoung Kim, Kwang Hyun Ko, Hye-Kyung Jung, Ki -Nam Shim, Hoon Jai Chun, Byung-Wook Kim, Hyuk Lee, Jie-Hyun Kim, Hyunsoo Chung, Sang Gyun Kim, Jae Young Jiang
Summary: This study evaluated the efficacy and safety of tegoprazan compared to lansoprazole as a first-line triple therapy for Helicobacter pylori eradication. The results showed that tegoprazan was as effective as lansoprazole in eradicating H. pylori and both treatment regimens were well-tolerated. However, tegoprazan did not overcome clarithromycin resistance in H. pylori.
Article
Gastroenterology & Hepatology
Jin Hee Noh, Ji Yong Ahn, Jene Choi, Young Soo Park, Hee Kyong Na, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Jung Mogg Kim
Summary: This study confirmed the effectiveness and advantages of the RT-PCR detection method in detecting H. pylori infection and verifying CLR resistance. Compared to RUT, RT-PCR more accurately detected H. pylori infection and could verify the presence of CLR resistance through fluorescence melting curve analysis. Due to the high sensitivity and accessibility of the RT-PCR method, it can help clinicians select suitable treatment regimens and improve the eradication rate.
Article
Virology
Xuan Chuong Tran, Sung Hye Kim, Jeong-Eun Lee, So-Hee Kim, Su Yeon Kang, Nguyen D. Binh, Pham Duc, Phan T. K. Phuong, Nguyen T. P. Thao, Wonwoo Lee, Joon-Yong Bae, Man-Seong Park, Misun Kim, Jeong Rae Yoo, Sang Taek Heo, Kyeong Ho An, Jung Mogg Kim, Nam-Hyuk Cho, Sun-Ho Kee, Keun Hwa Lee
Summary: The seroprevalence rate of severe fever with thrombocytopenia syndrome virus (SFTSV) in Vietnam is reported for the first time, revealing a similar rate to Pakistan and suggesting a potential increase in SFTS patients in Vietnam.
Article
Medicine, General & Internal
Gyu Young Pih, Jin Hee Noh, Ji Yong Ahn, Gill Sang Han, Hyun Suk Jung, Hwoon-Yong Jung, Jung Mogg Kim
Summary: This study established an objective method for measuring the color changes in the RUT kit and found that a transmittance of 60 at a 559-nm wavelength can be used as a cutoff value for interpreting RUT results. This research contributes to improving the accuracy of the RUT test and developing an automatic RUT kit reader.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2022)
Meeting Abstract
Gastroenterology & Hepatology
Jeong Hoon Lee, Hwoon-Yong Jung, Ji Yong Ahn, Kee Don Choi, Jung Mogg Kim, Gwang Ho Baik, Byung-Wook Kim, Jun Chul Park, Hye-Kyung Jung, Soo-Jeong Cho, Cheol Min Shin, Si Hyung Lee, Ji Hyun Kim, Wan-Sik Lee, Jae Kyu Sung, Jun-Won Chung, Dae Young Cheung, Hyuk Lee, Seung Young Kim