Article
Surgery
Stijn W. de Jonge, Quirine J. J. Boldingh, Anna H. Koch, Lidewine Daniels, Eefje N. de Vries, Ingrid J. B. Spijkerman, Wim M. Ankum, Gino M. M. J. Kerkhoffs, Marcel G. Dijkgraaf, Markus W. Hollmann, Marja A. Boermeester
Summary: This study aimed to test the hypothesis that the timing of surgical antibiotic prophylaxis affects the risk of surgical site infection, but no significant difference was found within the 60-minute interval before incision. In contrast to earlier studies, this research was unable to replicate differences in SSI risk.
Article
Medicine, General & Internal
Sung-Woo Choi, Jae Chul Lee, Won Seok Lee, Jin Yeong Hwang, Min Jung Baek, Yoon Seo Choi, Hae-Dong Jang, Byung-Joon Shin
Summary: This study compared the clinical features, treatment course, and prognosis of delayed postoperative spinal infection (PSI) with acute PSI. The results showed that delayed-onset PSI requires more extensive and longer treatment than acute-onset PSI, including revision surgery and additional instrumentation. The causative organisms and clinical manifestations did not differ between the two groups.
Article
Orthopedics
Vera Spatenkova, Ondrej Bradac, Zdenek Jindrisek, Jan Hradil, Daniela Fackova, Milada Halacova
Summary: This study aimed to analyze SSI and its risk factors in patients after thoracic or lumbar spine surgery, finding that only wound complications and warm seasons were significantly associated with SSI development according to multivariate regression analysis. Contrary to the prevailing literature, corticosteroids, diabetes mellitus, or transfusions were not identified as risk factors for SSI development.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Dermatology
Justin Gabriel Schlager, Kathrin Patzer, Jens Wallmichrath, Lars E. French, Elena Kunrad, Sophia Schlingmann, Daniel Stiefel, Benjamin Kendziora, Daniela Hartmann
Summary: This study aimed to identify risk factors for surgical site infection (SSI) in dermatologic surgery. The study found that risk factors for wound infection included defect size over 10cm(2), surgery of cutaneous malignancy, postoperative bleeding, delayed flap closure, and surgery localized to the ear and lower extremities.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Infectious Diseases
Jerome Ory, Quang Le Minh, Hung Phan Tien, Vinh Vu Hai, Elodie Careno, Tatiana Price, Alexandre Andrieux, Julien Crouzet, Catherine Dunyach-Remy, Didier Laureillard, Jean-Philippe Lavigne, Albert Sotto
Summary: This study examined the changes in surgical site infection rates before and after the implementation of antibiotic stewardship programs and infection control measures in a Vietnamese tertiary care hospital. The results showed a decrease in surgical site infection rates after the implementation of these programs, although the difference was not statistically significant. Comprehensive infection control education and policies are needed in Vietnamese hospitals to prevent surgical site infections.
Article
Oncology
Abida K. Sattar, Taleaa Masroor, Russell Seth Martins, Nida Zahid, Hania Shahzad, Rufina Soomro, Omema Saleem, Lubna M. Vohra, Sana Zeeshan, Muhammad Areeb Ashfaq, Irum Khan, Rida Nadeem, Nikhat Fatima, Ayisha Afzal Qureshi, Farin F. Amersi, Syed Faisal Mahmood
Summary: This study investigated the utility of continued antibiotic prophylaxis after mastectomy without immediate reconstruction and with indwelling drains. The results showed that continued antibiotic prophylaxis did not provide additional benefits in reducing surgical site infection rates.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jan Gaessler, Dominic Morocutti, Markus Merkl, Bernhard Remschmidt, Wolfgang Zemann, Michael Schwaiger
Summary: This study compared the rate and severity of surgical site infections (SSIs) in facial fracture patients undergoing open reduction with internal fixation (ORIF) using two different antibiotic regimens (single-dose and prolonged antibiotic prophylaxis). The results showed no significant difference in the incidence or severity of SSIs between the two groups.
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
(2023)
Article
Infectious Diseases
Christian de Tymowski, Tarek Sahnoun, Sophie Provenchere, Marylou Para, Nicolas Derre, Pierre Mutuon, Xavier Duval, Nathalie Grall, Bernard Iung, Solen Kerneis, Jean-Christophe Lucet, Philippe Montravers
Summary: The use of vancomycin/gentamicin (VGA) as a second-line prophylaxis for surgical site infection (SSI) seems to be as effective as cephalosporins (CA), although the microbiological etiology differs.
Article
Medicine, General & Internal
Giovanni Papa, Andrea Frasca, Nadia Renzi, Chiara Stocco, Giuseppe Pizzolato, Vittorio Ramella, Zoran Marij Arnez
Summary: This study primarily analyzed the surgical site infection in implant-based breast reconstruction, and found no infections occurred after the introduction of the prevention protocol in June 2020, with a decreasing trend in infection rates.
MEDICINA-LITHUANIA
(2021)
Article
Surgery
Ryan J. Ellis, Brian C. Brajcich, Kimberly A. Bertens, Carlos H. F. Chan, Carlos Fernandez-del Castillo, Paul J. Karanicolas, Shishir K. Maithel, Bradley N. Reames, Sharon M. Weber, Roberto J. Vidri, Henry A. Pitt, Vanessa M. Thompson, Mithat Gonen, Susan K. Seo, Adam C. Yopp, Clifford Y. Y. Ko, Michael I. D'Angelica
Summary: The association between bactibilia and postoperative complications in patients undergoing pancreatoduodenectomy is influenced by perioperative antibiotic prophylaxis. The presence of cefoxitin-resistant organisms in bile cultures is associated with increased risk of surgical site infection and clinically relevant postoperative pancreatic fistula.
Article
Oncology
Samuel Bensaid, Adrien Contejean, Philippe Morand, Maya Enser, Luc Eyrolle, Caroline Charlier, Solen Kerneis, Philippe Anract, David Biau, Etienne Canoui
Summary: This study aimed to assess the impact of extended antibiotic prophylaxis (ABP) on the rate of surgical site infection (SSI) and describe the microbiology of SSI in pelvic bone and/or soft tissue sarcoma removal surgery. The study found that extending ABP did not reduce the incidence of infection, and SSI were mainly polymicrobial. Risk factors for infection included surgery duration, postoperative ICU stay, and skin flap type.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Surgery
Josep Badia, Nares Arroyo-Garcia, Ana Vazquez, Alexander Almendral, Aina Gomila-Grange, Domenico Fraccalvieri, David Pares, Ana Abad-Torrent, Marta Pascual, Alejandro Solis-Pena, Mireia Puig-Asensio, Miguel Pera, Francesc Gudiol, Enric Limon, Miquel Pujol
Summary: This study investigated the implementation and outcomes of a nationwide care bundle for colorectal surgery. The results showed that the implementation of the care bundle significantly reduced the rate of surgical site infection.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Review
Chemistry, Multidisciplinary
Saturnino Marco Lupi, Giorgia Olivieri, Jessica Landini, Andrea Ferrigno, Plinio Richelmi, Claudia Todaro, Ruggero Baena
Summary: Short pre-surgical antibiotic prophylaxis is effective in preventing surgical wound infection following extraction of a mandibular third molar. Most studies suggest that pre-surgical administration and osteotomy are the most effective methods for preventing SWI, while post-surgical prophylaxis, although effective, is not fully supported by the literature.
APPLIED SCIENCES-BASEL
(2021)
Article
Medicine, General & Internal
Josep M. Badia, Miriam Flores-Yelamos, Ana Vazquez, Nares Arroyo-Garcia, Mireia Puig-Asensio, David Pares, Miguel Pera, Joaquin Lopez-Contreras, Enric Limon, Miquel Pujol
Summary: Oral antibiotic prophylaxis reduced the rates of surgical site infections in elective colorectal surgery and demonstrated a protective effect in multivariate analysis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Infectious Diseases
Carlo Vallicelli, Federico Coccolini, Massimo Sartelli, Luca Ansaloni, Simona Bui, Fausto Catena
Summary: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a combined treatment for peritoneal carcinomatosis, but patients are at high risk of infections and complications. Many authors have proposed aggressive screening protocols and vigilant monitoring to minimize and promptly identify infectious complications.
Article
Surgery
Saad Y. Salim, Pang Y. Young, Thomas A. Churchill, Rachel G. Khadaroo
JOURNAL OF SURGICAL RESEARCH
(2017)
Meeting Abstract
Surgery
Rachel G. Khadaroo, Pang Y. Young, Qaasim N. Mian, Jeremy C. Young, Catherine A. Compston, Thomas F. Mueller
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2014)
Article
Microbiology
S. Y. Salim, P. Y. Young, C. M. Lukowski, K. L. Madsen, B. Sis, T. A. Churchill, R. G. Khadaroo
BENEFICIAL MICROBES
(2013)
Meeting Abstract
Medicine, General & Internal
Barbara Pedrycz, Pang Young, Catherine Compston, Valerie Luyckx, Julie Ho, Valeria Mas, Lin-Fu Zhu, Donald Grynoch, Rachel Khadaroo, Thomas Mueller
SWISS MEDICAL WEEKLY
(2014)
Article
Surgery
Selina K. Wong, Pang Y. Young, Sandy Widder, Rachel G. Khadaroo
OSTOMY WOUND MANAGEMENT
(2013)
Article
Surgery
Angela Hill, Franklin Olumba, William Chapman
Summary: Transplantation for HCC is a complex topic, requiring considerations of multiple factors. Balancing tumor size with post-transplant outcome is still an ongoing challenge. Tumor downstaging and the use of new technologies have increased the number of HCC transplants, and these advances can also be applied to other liver tumors.
SURGICAL CLINICS OF NORTH AMERICA
(2024)
Article
Surgery
Olanrewaju A. Eletta, Guergana G. Panayotova, Keri E. Lunsford
SURGICAL CLINICS OF NORTH AMERICA
(2024)
Article
Surgery
Brianna Ruch, Kayla Kumm, Sandra Arias, Nitin N. Katariya, Amit K. Mathur
Summary: DCD liver transplantation is an underutilized method that can increase access to liver transplantation. With proper donor and recipient selection, matching, surgical technique, and perioperative management, these transplants can achieve similar patient and graft survival rates as DBD liver transplantation. The main limitations in the further growth of DCD liver transplantation are driven by risk aversion, and the current experience is mainly concentrated in large centers. With the advancement of regional and machine perfusion techniques, the definition of a viable DCD liver allograft may be redefined, encouraging wider usage and acceptance.
SURGICAL CLINICS OF NORTH AMERICA
(2024)
Article
Surgery
Lauren Matevish, Madhukar S. Patel, Parsia A. Vagefi
Summary: Downstaging has been shown to be feasible within UNOS-DS criteria, with successful long-term outcomes. Interventional liver-directed therapies have been the standard, but systemic therapies are becoming more effective. Immunotherapy holds promise in downstaging, but further trials are needed to assess feasibility and safety. Individual expertise will continue to guide treatment until more data is available.
SURGICAL CLINICS OF NORTH AMERICA
(2024)
Article
Surgery
Hassan Aziz, Paramita Nayak, David C. Mulligan
SURGICAL CLINICS OF NORTH AMERICA
(2024)
Article
Surgery
Catherine G. Pratt, Jenna N. Whitrock, Shimul A. Shah, Zhi Ven Fong
Summary: hCCA is a biologically aggressive disease and surgical resection is the only curative treatment. Factors such as patient's physical condition, tumor involvement, residual liver volume, and assessment of metastatic disease heavily influence the feasibility of surgical resection. A multidisciplinary, holistic, and individualized approach is critical for accurately determining resectability and optimizing clinical outcomes for patients with hCCA.
SURGICAL CLINICS OF NORTH AMERICA
(2024)
Article
Surgery
Sara-Catherine Whitney Zingg, Kristina Lemon
SURGICAL CLINICS OF NORTH AMERICA
(2024)
Article
Surgery
Christopher J. Sonnenday
SURGICAL CLINICS OF NORTH AMERICA
(2024)
Article
Surgery
Alban Longchamp, Tsukasa Nakamura, Korkut Uygun, James F. Markmann
SURGICAL CLINICS OF NORTH AMERICA
(2024)