4.3 Article

Rating and issues of mechanical anastomotic staplers in surgical practice: a survey of 241 Japanese gastroenterological surgeons

Journal

SURGERY TODAY
Volume 42, Issue 10, Pages 962-972

Publisher

SPRINGER
DOI: 10.1007/s00595-012-0303-9

Keywords

-

Categories

Funding

  1. Grants-in-Aid for Scientific Research [24590636, 23510353] Funding Source: KAKEN

Ask authors/readers for more resources

Commercially available mechanical devices for gastrointestinal anastomosis are mostly made in overseas. Japanese female surgeons have described these devices as being too large and difficult to handle. This study investigated the degree of satisfaction and problems experienced by Japanese surgeons in using various staplers for mechanical anastomosis. A questionnaire was prepared and sent via email to 5,537 members of the Japanese Society of Gastroenterological Surgery. The questionnaire included sex, age, surgical glove size, degree of satisfaction with various mechanical staplers, stress felt when using the staplers in anastomosis, and problems regarding the devices. Valid responses were received from 241 respondents (167 males, 74 females, response rate 4.9 %). The satisfaction rate ranged from 0 to 100 %. The average glove size in males was significantly larger than that in females (median: 7.0 versus 6.0; P < 0.0001). Surgeons with glove size 6.0 or smaller felt stress more frequently than those with size 6.5 or larger (median: 40 vs. 20 %; P < 0.0001). Surgeons with glove size 6.0 and smaller experienced more difficulties during firing and releasing. The satisfaction rates with currently available mechanical staplers were low. Japanese surgeons with small hands felt more stress when using the staplers. Ergonometric consideration is necessary in stapler design.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.3
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Gastroenterology & Hepatology

Lymphatic invasion is a prognostic factor of pathological N0 esophageal squamous cell carcinoma

Tetsuro Toriumi, Koichi Yagi, Motonari Ri, Shoh Yajima, Yasuhiro Okumura, Susumu Aikou, Hiroharu Yamashita, Sachiyo Nomura, Yasuyuki Seto

Summary: This study aimed to identify prognostic factors for long-term outcomes of patients with node-negative ESCC, finding that lymphatic invasion (Ly+) was the only independent prognostic factor associated with worse overall survival and recurrence-free survival. Patients with node-negative ESCC and lymphatic invasion may benefit from adjuvant treatment.

DISEASES OF THE ESOPHAGUS (2022)

Article Oncology

Crosstalk between cancer-associated fibroblasts and immune cells in peritoneal metastasis: inhibition in the migration of M2 macrophages and mast cells by Tranilast

Yusuke Nakamura, Jun Kinoshita, Takahisa Yamaguchi, Tatsuya Aoki, Hiroto Saito, Toshihide Hamabe-Horiike, Shinichi Harada, Sachiyo Nomura, Noriyuki Inaki, Sachio Fushida

Summary: By suppressing cancer-associated fibroblasts (CAFs), Tranilast improved the immunosuppressive microenvironment in a mouse PM model and showed potential as a candidate drug for PM treatment.

GASTRIC CANCER (2022)

Article Biochemistry & Molecular Biology

Diagnostic efficacy of circular RNAs as noninvasive, liquid biopsy biomarkers for early detection of gastric cancer

Souvick Roy, Mitsuro Kanda, Sachiyo Nomura, Zhongxu Zhu, Yuji Toiyama, Akinobu Taketomi, James Goldenring, Hideo Baba, Yasuhiro Kodera, Ajay Goel

Summary: This study developed a non-invasive liquid biopsy method for early detection of gastric cancer by using circular RNAs (circRNAs) as biomarkers. The researchers identified a panel of 8 circRNAs that could reliably distinguish gastric cancer patients from non-disease controls, even in early-stage patients. The decreased expression of circRNAs in serum samples suggested their tumor specificity.

MOLECULAR CANCER (2022)

Article Surgery

No association between hospital volume and short-term outcomes of some common surgeries: a retrospective cohort study based on a Japanese nationwide database

Kota Itamoto, Hiraku Kumamaru, Susumu Aikou, Koichi Yagi, Hiroharu Yamashita, Sachiyo Nomura, Hiroaki Miyata, Shinji Kuroda, Toshiyoshi Fujiwara, Shunsuke Endo, Yuko Kitagawa, Yoshihiro Kakeji, Yasuyuki Seto

Summary: This study analyzed data from a Japanese nationwide database to explore the association between hospital volume and short-term outcomes of appendectomy, cholecystectomy, and pneumothorax surgery. The results showed that hospital volume had no impact on the short-term outcomes of these common surgeries.

SURGERY TODAY (2022)

Article Surgery

Optimal criteria for predicting lymph node metastasis in esophageal squamous cell carcinoma by anatomical location using preoperative computed tomography: a retrospective cohort study

Shinichiro Shiomi, Shoh Yajima, Shuntaro Yoshimura, Masayuki Urabe, Motonari Ri, Yasuhiro Okumura, Koichi Yagi, Susumu Aikou, Sachiyo Nomura, Yasuyuki Seto

Summary: This study aimed to explore the diagnostic accuracy and optimal criteria for predicting lymph node metastasis in esophageal squamous cell carcinoma, and found variations in diagnostic ability and cutoff values among different locations.

SURGERY TODAY (2022)

Article Biochemistry & Molecular Biology

Mouse Gastric Epithelial Cells Resist CagA Delivery by the Helicobacter pylori Type IV Secretion System

Rejina Shrestha, Naoko Murata-Kamiya, Satoshi Imai, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Masanori Hatakeyama

Summary: The initial step in bacterial infection is the adherence of the bacterium to the target cell surface. This study found that the mouse stomach has a much lower expression level of Ceacam1 compared to the human stomach, which leads to the inability of the bacteria to deliver the CagA protein due to the lack of interaction between HopQ and Ceacam1 in mouse gastric epithelial cells.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Multidisciplinary Sciences

Non-Helicobacter pylori Helicobacter (NHPH) positive gastric cancer

Tomohiko Yasuda, Hyun Seok Lee, Su Youn Nam, Hiroto Katoh, Yuko Ishibashi, Somay Yamagata Murayama, Hidenori Matsui, Hiroki Masuda, Emiko Rimbara, Nobuyuki Sakurazawa, Hideyuki Suzuki, Hiroshi Yoshida, Yasuyuki Seto, Shumpei Ishikawa, Seong Woo Jeon, Masahiko Nakamura, Sachiyo Nomura

Summary: Genetic analysis and culturing techniques for gastric non-Helicobacter pylori Helicobacter (NHPH) are advancing, with NHPH reported to accompany certain gastric conditions. A study on Korean gastric cancer patients found a low percentage positive for NHPH, suggesting it may play a role in gastric cancer development, albeit with lower pathogenicity compared to H. pylori.

SCIENTIFIC REPORTS (2022)

Article Surgery

Surgical Experience Disparity Between Male and Female Surgeons in Japan

Emiko Kono, Urara Isozumi, Sachiyo Nomura, Kae Okoshi, Hiroyuki Yamamoto, Hiroaki Miyata, Itaru Yasufuku, Hiromichi Maeda, Junichi Sakamoto, Kazuhisa Uchiyama, Yoshihiro Kakeji, Kazuhiro Yoshida, Yuko Kitagawa

Summary: This study found that female surgeons in Japan have less surgical experience than male surgeons, and this gap tends to widen with an increase in years of experience, especially for medium- and high-difficulty operations. The gender disparity in surgical experience needs to be eliminated, so that female surgeons can advance to leadership positions.

JAMA SURGERY (2022)

Article Medicine, General & Internal

Comparison of short term surgical outcomes of male and female gastrointestinal surgeons in Japan: retrospective cohort study

Kae Okoshi, Hideki Endo, Sachiyo Nomura, Emiko Kono, Yusuke Fujita, Itaru Yasufuku, Koya Hida, Hiroyuki Yamamoto, Hiroaki Miyata, Kazuhiro Yoshida, Yoshihiro Kakeji, Yuko Kitagawa

Summary: This study compared the short-term surgical outcomes between male and female gastrointestinal surgeons in Japan. The results showed no significant difference in surgical mortality and surgical complications between the two genders. It was also observed that female surgeons took on patients at higher risk.

BMJ-BRITISH MEDICAL JOURNAL (2022)

Article Pathology

Aberrant Cadherin11 expression predicts distant metastasis of gastric cancer

Hideaki Mita, Hiroto Katoh, Daisuke Komura, Miwako Kakiuchi, Hiroyuki Abe, Hirofumi Rokutan, Koichi Yagi, Sachiyo Nomura, Tetsuo Ushiku, Yasuyuki Seto, Shumpei Ishikawa

Summary: In this study, immunohistochemical analysis of 342 gastric cancer cases revealed that approximately half of the samples showed aberrant expression of CDH11 in gastric cancer cells. The aberrant expression of CDH11 was statistically associated with bone metastasis, as well as liver and distant lymph node metastasis. Therefore, aberrant CDH11 expression in gastric cancer cells can serve as a predictive biomarker for distant metastasis.

PATHOLOGY RESEARCH AND PRACTICE (2023)

Article Genetics & Heredity

Multiancestry genomic and transcriptomic analysis of gastric cancer

Yasushi Totoki, Mihoko Saito-Adachi, Yuichi Shiraishi, Daisuke Komura, Hiromi Nakamura, Akihiro Suzuki, Kenji Tatsuno, Hirofumi Rokutan, Natsuko Hama, Shogo Yamamoto, Hanako Ono, Yasuhito Arai, Fumie Hosoda, Hiroto Katoh, Kenichi Chiba, Naoko Iida, Genta Nagae, Hiroki Ueda, Chen Shihang, Shigeki Sekine, Hiroyuki Abe, Sachiyo Nomura, Tetsuya Matsuura, Eiji Sakai, Takashi Ohshima, Yasushi Rino, Khay Guan Yeoh, Jimmy So, Kaushal Sanghvi, Richie Soong, Akihiko Fukagawa, Shinichi Yachida, Mamoru Kato, Yasuyuki Seto, Tetsuo Ushiku, Atsushi Nakajima, Hitoshi Katai, Patrick Tan, Shumpei Ishikawa, Hiroyuki Aburatani, Tatsuhiro Shibata

Summary: A study on a cross-ancestry genomic and transcriptomic cohort of gastric cancer reveals significantly mutated genes and mutational signatures, some of which are specific to certain ancestries. The research involves the analysis of 1,335 cases and identifies 77 significantly mutated genes, including ARHGAP5 and TRIM49C. Subtype-specific drivers, such as PIGR and SOX9, are also identified, particularly enriched in the diffuse subtype of the disease. The findings also highlight the association of non-protein-truncating CDH1 mutations with sporadic diffuse-type cases and the link between alcohol consumption or metabolism and RHOA mutations in patients with East Asian ancestry. The study provides comprehensive insights into the molecular landscape of gastric cancer across various subtypes and ancestries.

NATURE GENETICS (2023)

Article Oncology

Diagnostic utility of trefoil factor families for the early detection of lung cancer and their correlation with tissue expression

Kentaro Minegishi, Yoh Dobashi, Teruhide Koyama, Yuko Ishibashi, Miki Furuya, Hiroyoshi Tsubochi, Yasukazu Ohmoto, Tomohiko Yasuda, Sachiyo Nomura

Summary: Trefoil factors (TFFs) have been found to be upregulated in various types of cancer, indicating their potential as biomarkers for screening. This study evaluated the clinical relevance of serum and urinary TFFs as biomarkers for lung cancer and their correlation with TFF expression levels in lung cancer tissue. The results showed that serum TFF levels were significantly higher in lung cancer patients, while urinary TFF levels were lower. Serum TFF1, TFF2, TFF3, and urinary TFF1, TFF3 showed the highest potential to discriminate between cancer and non-cancer samples. The findings suggest that serum and urinary TFF levels could serve as predictive biomarkers for lung cancer.

ONCOLOGY LETTERS (2023)

Article Gastroenterology & Hepatology

Multivalent tyrosine kinase inhibition promotes T cell recruitment to immune-desert gastric cancers by restricting epithelial-mesenchymal transition via tumour-intrinsic IFN-γ signalling

Long Long Cao, Heng Lu, Mohammed Soutto, Nadeem Bhat, Zheng Chen, Dunfa Peng, Ahmed Gomaa, Jia Bin Wang, Jian Wei Xie, Ping Li, Chao Hui Zheng, Sachiyo Nomura, Jashodeep Datta, Nipun Merchant, Zhi Bin Chen, Alejandro Villarino, Alexander Zaika, Chang Ming Huang, Wael El-Rifai

Summary: This study developed a classification method based on immune cell infiltration to classify GC and found that immune desert-type and excluded-type tumors are resistant to ICB therapy compared to immune-inflamed tumors. The study also identified the enrichment of epithelial-mesenchymal transition (EMT) signaling in immune desert-type GC, and showed that mesenchymal-like tumors in syngeneic mice exhibited T cell-exclusion and resistance to CTLA4 blockade.
Article Surgery

Lymphatic flow mapping using near-infrared fluorescence imaging with indocyanine green helps to predict lymph node metastasis intraoperatively in patients with esophageal or esophagogastric junction cancer not treated with neoadjuvant chemotherapy

Shinichiro Shiomi, Koichi Yagi, Ryohei Iwata, Shoh Yajima, Yasuhiro Okumura, Susumu Aikou, Hiroharu Yamashita, Sachiyo Nomura, Yasuyuki Seto

Summary: The study investigated the diagnostic utility of a newly established lymphatic flow mapping protocol for predicting lymph node metastasis in patients with esophageal or esophagogastric junction cancer. The results showed that this protocol potentially helps to predict lymph node metastasis intraoperatively in patients who did not undergo neoadjuvant chemotherapy.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2023)

Article Biochemistry & Molecular Biology

Alterations in Intratumoral Immune Response before and during Early-On Nivolumab Treatment for Unresectable Advanced or Recurrent Gastric Cancer

Yasuyoshi Sato, Hiroharu Yamashita, Yukari Kobayashi, Koji Nagaoka, Tetsuro Hisayoshi, Takuya Kawahara, Akihiro Kuroda, Noriyuki Saito, Ryohei Iwata, Yasuhiro Okumura, Koichi Yagi, Susumu Aiko, Sachiyo Nomura, Kazuhiro Kakimi, Yasuyuki Seto

Summary: We investigated the tumor immune response in gastric cancer patients receiving third-line nivolumab monotherapy to identify immune-related biomarkers for better patient selection. High T cell/Treg ratios and specific gene expression signatures show promise as potential biomarkers for treatment response, while the tumor-infiltrating immune response is compromised by prior treatments.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

No Data Available