Article
Oncology
Zackory T. Burns, Danielle S. Bitterman, Subha Perni, Patrick J. Boyle, Carly E. Guss, Daphne A. Haas-Kogan, Kevin X. Liu
Summary: This study explored the clinical characteristics, experiences, and outcomes of transgender patients with cancer. It found that many transgender patients developed various cancers and underwent gender-affirming therapy post cancer diagnosis, highlighting the need for improved cancer care for this population. Mot importantly, documentation by oncologic practitioners regarding pronouns and discussions on the interaction between cancer treatment and gender-affirming care were lacking, indicating a potential gap in holistic care for transgender cancer patients.
Review
Oncology
Paolo Palmisciano, Gianluca Ferini, Christian Ogasawara, Waseem Wahood, Othman Bin Alamer, Aditya D. Gupta, Gianluca Scalia, Alexandra M. G. Larsen, Kenny Yu, Giuseppe E. Umana, Aaron A. Cohen-Gadol, Tarek Y. El Ahmadieh, Ali S. Haider
Summary: Orbital metastases significantly impair patient quality of life. Surgical resection provides better symptom relief and survival benefits compared to biopsy, while orbital radiotherapy significantly improves symptoms. However, overall survival rates are generally poor, indicating the need for further research on the microenvironment of orbital metastases for devising optimal systemic treatment strategies.
Article
Critical Care Medicine
Jason E. Bloom, Ziad Nehme, Emily Andrew, Luke P. Dawson, Himawan Fernando, Samer Noaman, Michael Stephenson, David Anderson, Vincent Pellegrino, Shelley Cox, Jeffrey Lefkovits, William Chan, David M. Kaye, Karen Smith, Dion Stub
Summary: This study assessed the impact of receiving hospital characteristics on outcomes in patients with cardiogenic shock (CS). The availability of 24-hour coronary angiography, on-site cardiac surgery, and annual CS volume were found to be associated with reduced 30-day mortality.
Article
Medicine, General & Internal
Yi-Chih Lee, Jhih-Jin Li, Chien-Han Hsiao, Chieh-Ching Yen
Summary: The purpose of this study was to identify the risk factors associated with unfavorable outcomes in iliopsoas abscess (IPA) patients. The study found that factors such as age, congestive heart failure, thrombocytopenia, and septic shock were significantly associated with in-hospital mortality. Recognizing these factors may help in risk stratification and determining the optimal treatment plan for IPA patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Jordina Rincon-Torroella, Maureen Rakovec, Adham M. Khalafallah, Ann Liu, Anya Bettegowda, Carmen Kut, Fausto J. Rodriguez, Jon Weingart, Mark Luciano, Alessandro Olivi, George Jallo, Henry Brem, Debraj Mukherjee, Michael Lim, Chetan Bettegowda
Summary: Subependymomas are rare low-grade brain tumors, and their clinical characteristics and prognosis are not completely understood due to their rarity. This study reviewed cases treated with surgical resection at a hospital from 1992 to 2020 and found that patients with subependymoma have a favorable prognosis after surgical resection.
JOURNAL OF NEUROSURGERY
(2022)
Article
Oncology
Jose A. Carreno Duenas, P. Natalia Sanchez, Carlos E. Bonilla
Summary: This study aimed to compare overall survival, progression-free survival, and treatment response between patients who participated in cancer clinical trials and those who refused to participate. The results showed that participants had higher rates of stable disease and complete response, and longer progression-free survival. Therefore, participation in clinical trials could improve treatment outcomes and reduce disease progression.
Article
Oncology
Lei Huang, Yan Shi, Lei Wang, Lan Rong, Yan Ren, Chenying Xu, Junwei Wu, Mingmin Zhang, Lifeng Zhu, Junjie Zhang, Xiaofeng Xu, Weiguo Hu, Jun Zhang
Summary: This study aimed to describe the characteristics and in-hospital outcomes of older patients with cancer admitted to a top-ranked hospital in China, and explore factors associated with duration, cost, and mortality during first hospitalization. Certain baseline patient and tumor characteristics, medical and medication histories, changes of weight and food intake, diet, and self-care ability were found to be independently associated with in-hospital outcomes.
Article
Otorhinolaryngology
Min-Seok Rha, Yeonsu Jeong, Chang-Hoon Kim, Joo-Heon Yoon, Hyung-Ju Cho
Summary: This study found that the presence of mixed apnea (MA) events in patients with obstructive sleep apnea (OSA) leads to different clinical characteristics and surgical outcomes. The mixed group had a lower surgical success rate and smaller postoperative improvements in sleep apnea indices compared to the pure group. Logistic regression analysis confirmed that the presence of MA is an independent predictor of poor surgical outcomes in OSA patients.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Medicine, General & Internal
Hong-Qiu Gu, Xin Yang, Chun-Juan Wang, Xing-Quan Zhao, Yi-Long Wang, Li-Ping Liu, Xia Meng, Yong Jiang, Hao Li, Chelsea Liu, Runqi Wangqin, Gregg C. Fonarow, Lee H. Schwamm, Ying Xian, Zi-Xiao Li, Yong-Jun Wang
Summary: The study evaluated the clinical characteristics, management, and outcomes of stroke or TIA patients in China. Results showed that management measures and clinical outcomes varied by cerebrovascular event type, with substantial improvements observed over time. The study suggests support for the use of evidence-based practices is still needed to enhance care quality for stroke and TIA patients in China.
Article
Medicine, General & Internal
Berthe Amelie Iroungou, Laurette Guignali Mangouka, Berthold Bivigou-Mboumba, Pamela Moussavou-Boundzanga, Judicael Obame-Nkoghe, Farrel Nzigou Boucka, Augustin Mouinga-Ondeme, Avelin Fobang Aghokeng, Romain Tchoua, Pascal Pineau, Jean Raymond Nzenze
Summary: A study conducted at the Armed Forces Hospital in Libreville, Gabon found that COVID-19 patients were predominantly male, younger in age, had a low mortality rate, and diabetes was the main risk factor for severe symptoms.
Article
Medicine, General & Internal
Tomoyuki Morisawa, Masakazu Saitoh, Shota Otsuka, Go Takamura, Masayuki Tahara, Yusuke Ochi, Yo Takahashi, Kentaro Iwata, Keisuke Oura, Koji Sakurada, Tetsuya Takahashi
Summary: This study aimed to determine the impact of hospital-acquired functional decline (HAFD) on the prognosis of older patients after cardiac surgery. The results showed that HAFD and slower preoperative gait speed were independent predictors of poor prognosis. Patients with HAFD had worse functional and mental health outcomes one year after hospital discharge.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Infectious Diseases
Polianna Delfino-Pereira, Magda Carvalho Pires, Virginia Mara Reis Gomes, Matheus Carvalho Alves Nogueira, Maria Clara Pontello Barbosa Lima, Alexandre Vargas Schwarzbold, Amanda de Oliveira Maurilio, Ana Luiza Bahia Alves Scotton, Andre Soares de Moura Costa, Barbara Lopes Farace, Bruno Mateus de Castro, Christiane Correa Rodrigues Cimini, Daniel Vitorio Silveira, Daniela Ponce, Elayne Crestani Pereira, Eliane Wuerdig Roesch, Euler Roberto Fernandes Manenti, Evelin Paola de Almeida Cenci, Fernanda Costa dos Santos, Fernando Anschau, Fernando Graca Aranha, Frederico Bartolazzi, Guilherme Fagundes Nascimento, Heloisa Reniers Vianna, Joanna d'Arc Lyra Batista, Joice Coutinho de Alvarenga, Juliana da Silva Nogueira Carvalho, Juliana Machado-Rugolo, Karen Brasil Ruschel, Luanna Silva Monteiro Menezes, Luis Cesar de Castro, Luiz Antonio Nasi, Maiara Anschau Floriani, Maira Dias Souza, Maira Viana Rego Souza-Silva, Marcelo Carneiro, Maria Aparecida Camargos Bicalho, Mariana Frizzo de Godoy, Milton Henriques Guimaraes-Junior, Patricia Klarmann Ziegelmann, Pedro Ledic Assaf, Petronio Jose de Lima Martelli, Renan Goulart Finger, Saionara Cristina Francisco, Silvia Ferreira Araujo, Talita Fischer Oliveira, Thainara Conceicao de Oliveira, Thalita Martins Lage, Vanessa Muller, Yuri Carlotto Ramires, Teresa Cristina de Abreu Ferrari, Milena Soriano Marcolino
Summary: This retrospective cohort study compared the clinical characteristics and outcomes of patients with hospital-manifested COVID-19 and community-manifested COVID-19. Patients with hospital-manifested COVID-19 had a higher prevalence of cancer and alcoholism, and higher rates of intensive care unit requirement, sepsis, and death. Increasing age, male sex, number of comorbidities, and cancer were independent predictors of mortality in hospital-manifested COVID-19.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Kyeong A. So, Seung-Hyuk Shim, Sun Joo Lee, Tae Jin Kim
Summary: This study evaluated the characteristics and outcomes of surgical treatment in older patients with gynecologic cancers. The study included 131 patients aged 65 years and above who underwent surgery for gynecologic cancers. The results showed that older patients had good surgical outcomes and tolerable postoperative complications, indicating that surgical treatment can be safely offered to older patients with gynecologic cancers.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Wezile Chitha, Zukiswa Jafta, Onke R. Mnyaka, Danleen Hongoro, Lizo Godlimpi, Buyiswa Swartbooi, Natasha Williams, Christopher Zungu, Lazola Buthi, Sibulelo Kuseni, John Nasila, Siyabonga Sibulawa, Olona Giwu, Awam Mavimbela, Vivien Essel, Sikhumbuzo A. Mabunda
Summary: This study aims to describe the demographic, epidemiological, and clinical profile of various cancers at Nelson Mandela Academic Hospital and Rob Ferreira Hospital in South Africa, which have decentralized cancer care delivery since 2018 and 2019 respectively.
Article
Clinical Neurology
Chengjun Wang, Cang Liu
Summary: This study compared the clinical characteristics and surgical outcomes of super-elderly patients with chronic subdural hematoma (CSDH) to relatively younger patients. The results showed that the surgical method and outcomes were similar between the two groups, but the prognosis of super-elderly patients was worse.
WORLD NEUROSURGERY
(2023)
Article
Surgery
Jennifer N. Ervin, C. Ann Vitous, Emily E. Wells, Sarah L. Krein, Christopher R. Friese, Amir A. Ghaferi
Summary: The effectiveness of the Rescue Improvement Conference in addressing postoperative complications was evaluated. The conference proved to be effective in promoting interdisciplinary collaboration, enabling the representation of diverse voices, and facilitating multilevel problem solving. It has the potential to support surgical departments in developing strategies to recognize and manage postoperative complications.
Article
Immunology
Gowri Satyanarayana, Kyle T. Enriquez, Tianyi Sun, Elizabeth J. Klein, Maheen Abidi, Shailesh M. Advani, Joy Awosika, Ziad Bakouny, Babar Bashir, Stephanie Berg, Marilia Bernardes, Pamela C. Egan, Arielle Elkrief, Lawrence E. Feldman, Christopher R. Friese, Shipra Goel, Cyndi Gonzalez Gomez, Keith L. Grant, Elizabeth A. Griffiths, Shuchi Gulati, Shilpa Gupta, Clara Hwang, Jayanshu Jain, Chinmay Jani, Anna Kaltsas, Anup Kasi, Hina Khan, Natalie Knox, Vadim S. Koshkin, Daniel H. Kwon, Chris Labaki, Gary H. Lyman, Rana R. McKay, Christopher McNair, Gayathri Nagaraj, Elizabeth S. Nakasone, Ryan Nguyen, Taylor K. Nonato, Adam J. Olszewski, Orestis A. Panagiotou, Matthew Puc, Pedram Razavi, Elizabeth Robilotti, Miriam Santos-Dutra, Andrew L. Schmidt, Dimpy P. Shah, Sumit A. Shah, Kendra Vieira, Lisa B. Weissmann, Trisha M. Wise-Draper, Ulysses Wu, Julie Tsu-Yu Wu, Toni K. Choueiri, Sanjay Mishra, Jeremy L. Warner, Benjamin French, Dimitrios Farmakiotis
Summary: This study aimed to investigate the frequency of coinfections and their association with outcomes among patients with cancer and COVID-19. The results showed that the risk of coinfections in this population was associated with factors such as age, sex, comorbidities, and disease status. Bacterial and fungal coinfections were found to be associated with higher mortality rates, while viral coinfections were less common.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Jessica E. Hawley, Tianyi Sun, David D. Chism, Narjust Duma, Julie C. Fu, Na Tosha N. Gatson, Sanjay Mishra, Ryan H. Nguyen, Sonya A. Reid, Oscar K. Serrano, Sunny R. K. Singh, Neeta K. Venepalli, Ziad Bakouny, Babar Bashir, Mehmet A. Bilen, Paolo F. Caimi, Toni K. Choueiri, Scott J. Dawsey, Leslie A. Fecher, Daniel B. Flora, Christopher R. Friese, Michael J. Glover, Cyndi J. Gonzalez, Sharad Goyal, Thorvardur R. Halfdanarson, Dawn L. Hershman, Hina Khan, Chris Labaki, Mark A. Lewis, Rana R. McKay, Ian Messing, Nathan A. Pennell, Matthew Puc, Deepak Ravindranathan, Terence D. Rhodes, Andrea Rivera, John Roller, Gary K. Schwartz, Sumit A. Shah, Justin A. Shaya, Mitrianna Streckfuss, Michael A. Thompson, Elizabeth M. Wulff-Burchfield, Zhuoer Xie, Peter Paul Yu, Jeremy L. Warner, Dimpy P. Shah, Benjamin French, Clara Hwang
Summary: The study aimed to quantify spatiotemporal variation in COVID-19 outcomes among cancer patients in the US. Results showed no significant differences in outcomes across US census divisions, but substantial heterogeneity was found across cancer care delivery centers.
Article
Oncology
A. L. Schmidt, C. Labaki, C-Y Hsu, Z. Bakouny, N. Balanchivadze, S. A. Berg, S. Blau, A. Daher, T. El Zarif, C. R. Friese, E. A. Griffiths, J. E. Hawley, B. Hayes-Lattin, V Karivedu, T. Latif, B. H. Mavromatis, R. R. McKay, G. Nagaraj, R. H. Nguyen, O. A. Panagiotou, A. J. Portuguese, M. Puc, M. Santos Dutra, B. A. Schroeder, A. Thakkar, E. M. Wulff-Burchfield, S. Mishra, D. Farmakiotis, Yu Shyr, J. L. Warner, T. K. Choueiri
Summary: This study analyzes the clinical features of cancer patients who develop symptomatic COVID-19 after vaccination. It finds that these patients often have comorbidities and can experience severe and even lethal infections. Hematologic malignancy patients are over-represented among the vaccinated cancer patients who develop symptomatic COVID-19. Therefore, while vaccination remains crucial in protecting vulnerable populations, including cancer patients, those who develop breakthrough infections despite full vaccination still face the risk of severe outcomes.
ANNALS OF ONCOLOGY
(2022)
Article
Oncology
Elizabeth S. Ver Hoeve, Melissa A. Simon, Sankirtana M. Danner, Antonio J. Washington, Susan D. Coples, Sanja Percac-Lima, Emma C. Whited, Electra D. Paskett, Michelle J. Naughton, Darrell M. Gray, Jennifer A. Wenzel, James R. Zabora, Ahmed Hassoon, Elliott E. Tolbert, Elizabeth Calhoun, Debra L. Barton, Christopher R. Friese, Marita G. Titler, Heidi A. Hamann
Summary: This article introduces the Alliance to Advance Patient-Centered Cancer Care, funded by the Merck Foundation, and shares insights from six cancer centers on patient navigation. The importance of understanding patient populations, utilizing existing infrastructure and institutional commitment, and mobilizing community support is highlighted.
Editorial Material
Medicine, General & Internal
Deena Kelly Costa, Christopher R. Friese
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Medicine, General & Internal
Julie Fu, Sonya A. Reid, Benjamin French, Cassandra Hennessy, Clara Hwang, Na Tosha Gatson, Narjust Duma, Sanjay Mishra, Ryan Nguyen, Jessica E. Hawley, Sunny R. K. Singh, David D. Chism, Neeta K. Venepalli, Jeremy L. Warner, Toni K. Choueiri, Andrew L. Schmidt, Leslie A. Fecher, Jennifer E. Girard, Mehmet A. Bilen, Deepak Ravindranathan, Sharad Goyal, Trisha M. Wise-Draper, Cathleen Park, Corrie A. Painter, Sheila M. McGlown, Gilberto de Lima Lopes Jr, Oscar K. Serrano, Dimpy P. Shah
Summary: This study aimed to investigate racial disparities in severity, clinical complications, and outcomes of COVID-19 between Black patients and non-Hispanic White patients with cancer. The study found that Black patients with cancer had worse COVID-19 outcomes, indicating a greater burden of COVID-19 in this population.
Article
Oncology
Nicole M. Grogan Fleege, Donna Pierce-Gjeldum, Leigh K. Swartz, Kait Verbal, Sofia Merajver, Christopher R. Friese, Ayano Kiyota, Jason Heth, Denise Leung, Sean R. Smith, Nicolette Gabel, Michelle M. Kim, Aki Morikawa
Summary: The study aims to improve the survival and quality of life for patients with metastatic breast cancer through team-based care. The results show that a dedicated program coordinator and a personalized referral system can shorten patients' waiting time, improve the utilization of specialized medical resources, and facilitate patient participation in clinical trials.
JCO ONCOLOGY PRACTICE
(2023)
Article
Oncology
Maxwell Salvatore, Miriam M. Hu, Lauren J. Beesley, Alison M. Mondul, Celeste Leigh Pearce, Christopher R. Friese, Lars G. Fritsche, Bhramar Mukherjee
Summary: This study explores the association between cancer status, site, treatment, vaccination, and COVID-19 outcomes. Cancer diagnosis is associated with higher rates of severe COVID-19, hospitalization, and mortality, especially for recent cancer diagnoses. Certain cancer types and chemotherapy treatment increase the risk of worse COVID-19 outcomes, while vaccinations are associated with lower rates of severe COVID-19 outcomes.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Editorial Material
Oncology
Cinzia Caparso, Christopher R. Friese
JCO ONCOLOGY PRACTICE
(2023)
Article
Oncology
Fay J. Hlubocky, Daniel C. McFarland, Anthony L. Back, Christopher R. Friese, Laurel Lyckholm, Colleen M. Gallagher, Molly McGinnis, Rebecca Spence, Laura Lynch, Julia Tomkins, Tait Shanafelt, Piyush Srivastava
Summary: This study developed a virtual group peer support program for oncologists and found that it was feasible, acceptable, and beneficial for enhancing their well-being.
JCO ONCOLOGY PRACTICE
(2023)
Article
Oncology
Milisa Manojlovich, Amanda Blok, Nathan Wright, Emily Azhari, Karen B. Farris, Christopher R. Friese, Emily Mackler, Marita Titler, Mary Byrnes
Summary: This study explored the impact of side effects from oral anti-cancer agents (OAAs) on patients' lives and the strategies they used to manage these effects. Participants devised their own distinct strategies, including changing nutritional habits, using medication or non-medication approaches to alleviate side effects, and employing various coping methods.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Megan A. Mullins, Lisa Reber, Ariel Washington, Marina Stasenko, Aaron Rankin, Christopher R. Friese, Mary E. Cooley, Matthew F. Hudson, Lauren P. Wallner
Summary: Collecting sexual orientation and gender identity (SOGI) data in community oncology practices is crucial for addressing cancer inequities, but there are barriers such as low understanding, lack of infrastructure, and perceived low priority. Training, education, and support can help overcome these barriers and improve SOGI data collection.
Article
Oncology
Samuel M. Rubinstein, Divaya Bhutani, Ryan C. Lynch, Chih-Yuan Hsu, Yu Shyr, Shailesh Advani, Ruben A. Mesa, Sanjay Mishra, Daniel P. Mundt, Dimpy P. Shah, R. Alejandro Sica, Keith E. Stockerl-Goldstein, Catherine Stratton, Matthias Weiss, Alicia Beeghly-Fadiel, Melissa Accordino, Sarit E. Assouline, Joy Awosika, Ziad Bakouny, Babar Bashir, Stephanie Berg, Mehmet Asim Bilen, Cecilia A. Castellano, Jacob C. Cogan, K. C. Devendra, Christopher R. Friese, Shilpa Gupta, Daniel Hausrath, Clara Hwang, Nathalie A. Johnson, Monika Joshi, Anup Kasi, Elizabeth J. Klein, Vadim S. Koshkin, Nicole M. Kuderer, Daniel H. Kwon, Chris Labaki, Tahir Latif, Eric Lau, Xuanyi Li, Gary H. Lyman, Rana R. McKay, Gayathri Nagaraj, Amanda Nizam, Taylor K. Nonato, Adam J. Olszewski, Hyma Polimera, Andrew J. Portuguese, Matthew M. Puc, Pedram Razavi, Rachel Rosovski, Andrew Schmidt, Sumit A. Shah, Aditi Shastri, Christopher Su, Pallawi Torka, Trisha M. Wise-Draper, Leyre Zubiri, Jeremy L. Warner, Michael A. Thompson
Summary: Patients with B-lymphoid malignancies, especially those who have received recent anticancer therapy, are at a uniquely high risk of severe COVID-19.
BLOOD CANCER DISCOVERY
(2022)
Article
Geriatrics & Gerontology
Arielle Elkrief, Cassandra Hennessy, Nicole M. Kuderer, Samuel M. Rubinstein, Elizabeth Wulff-Burchfield, Rachel P. Rosovsky, Karen Vega-Luna, Michael A. Thompson, Orestis A. Panagiotou, Aakash Desai, Donna R. Rivera, Ali Raza Khaki, Lisa Tachiki, Ryan C. Lynch, Catherine Stratton, Rawad Elias, Gerald Batist, Anup Kasi, Dimpy P. Shah, Ziad Bakouny, Angelo Cabal, Jessica Clement, Jennifer Crowell, Becky Dixon, Christopher R. Friese, Stacy L. Fry, Punita Grover, Shuchi Gulati, Shilpa Gupta, Clara Hwang, Hina Khan, Soo Jung Kim, Elizabeth J. Klein, Chris Labaki, Rana R. McKay, Amanda Nizam, Nathan A. Pennell, Matthew Puc, Andrew L. Schmidt, Armin Shahrokni, Justin A. Shaya, Christopher T. Su, Sarah Wall, Nicole Williams, Trisha M. Wise-Draper, Sanjay Mishra, Petros Grivas, Benjamin French, Jeremy L. Warner, Tanya M. Wildes
Summary: This study aims to quantify the association of a novel geriatric risk index with COVID-19 severity and 30-day mortality among older adults with cancer. The results show a strong association between the geriatric risk index and COVID-19 severity and mortality, providing clinicians with a risk stratification method to identify high-risk older adults.
LANCET HEALTHY LONGEVITY
(2022)