Article
Multidisciplinary Sciences
Tatsunori Minamide, Hiroaki Ikematsu, Tatsuro Murano, Tomohiro Kadota, Kensuke Shinmura, Yusuke Yoda, Keisuke Hori, Masaaki Ito, Tomonori Yano
Summary: This study aimed to assess the occurrence of metachronous AN following SM-CRC resection and found that synchronous AN was the primary risk factor for metachronous AN. Depending on the presence of synchronous AN, surveillance protocols following SM-CRC resection can be adjusted for better detection of metachronous AN.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Aritoshi Hattori, Takeshi Matsunaga, Yukio Watanabe, Mariko Fukui, Kazuya Takamochi, Shiaki Oh, Kenji Suzuki
Summary: The study investigated the surgical outcomes of repeated pulmonary resection for metachronous ipsilateral second non-small cell lung cancer (NSCLC). Repeated anatomical resection was defined as a surgery for secondary NSCLC after primary major lung resection. The 3-year overall survival rate after metachronous surgery for ipsilateral second NSCLC was 80.1%, with reanatomical resection being a significant predictor of postoperative severe morbidity.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Gastroenterology & Hepatology
Sandra Baile-Maxia, Carolina Mangas-Sanjuan, Uri Ladabaum, Cesare Hassan, Matthew D. Rutter, Michael Bretthauer, Licia Medina-Prado, Noelia Sala-Miquel, Oscar Murcia Pomares, Pedro Zapater, Rodrigo Jover
Summary: This study aimed to assess the association between HRA characteristics and the outcomes of CRC or AAs surveillance. The study found that adenomas larger than 20mm, high-grade dysplasia (HGD), and adenomas with villous component were associated with higher risk of metachronous CRC. However, multiplicity of adenomas did not seem to be significantly associated with higher CRC risk in the near term.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Oncology
Aina Kunitomo, Akira Ouchi, Koji Komori, Takashi Kinoshita, Yusuke Sato, Tetsuya Abe, Seiji Ito, Tsuyoshi Sano, Yasuhiro Shimizu
Summary: This study aimed to evaluate the clinical significance of surgical intervention for isolated peritoneal metastases (PM) from colorectal cancer (CRC), with a particular focus on the timing of PM. The results showed that patients who underwent radical resection of PM had better survival compared with those who received palliative chemotherapy, especially for metachronous PM. Therefore, surgical intervention should be considered for isolated metachronous PM when radical resection is feasible.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Surgery
Andreas Andreou, Sebastian Knitter, Moritz Schmelzle, Daniel Kradolfer, Martin H. Maurer, Timo Alexander Auer, Uli Fehrenbach, Anja Lachenmayer, Vanessa Banz, Wenzel Schoning, Daniel Candinas, Johann Pratschke, Guido Beldi
Summary: This study showed that positive resection margins did not affect the occurrence of hepatic local recurrence after hepatectomy for colorectal liver metastases. Additionally, hepatic local recurrence at the resection margin did not have a significant impact on overall survival compared to recurrence at other sites. Therefore, R1 status at hepatectomy may be more indicative of disease progression rather than worse prognosis.
Review
Oncology
Jie Du, Zhixian Bao, Tianhu Liang, Hongmei Zhao, Junxian Zhao, Ruipu Xu, Xiaohui Wang
Summary: Smoking, age, history of multiple other cancers, and Lugol-voiding lesions (LVLs) were identified as risk factors for MESCC. The overall pooled incidence of MESCC was 20.3%, with a 0.20% increase for each additional year of follow-up time. The head and neck were the most common locations for SPC, followed by the esophagus.
FRONTIERS IN ONCOLOGY
(2023)
Review
Gastroenterology & Hepatology
Raquel Ortigao, Goncalo Figueiroa, Leonardo Frazzoni, Pedro Pimentel-Nunes, Cesare Hassan, Mario Dinis-Ribeiro, Lorenzo Fuccio, Diogo Libanio
Summary: This study conducted a systematic review of 52 studies to identify risk factors for metachronous gastric lesions (MGL) and compare the incidence after endoscopic resection (ER) and subtotal gastrectomy. The results showed that the incidence of MGL after ER was significantly higher than after subtotal gastrectomy. Factors such as age, sex, family history, synchronous lesions, gastric mucosal atrophy, intestinal metaplasia, H. pylori infection, and pepsinogen I/II ratio were significantly associated with MGL after ER. The study highlights the importance of individualized follow-up schedules based on different surgical procedures and risk factors.
Article
Gastroenterology & Hepatology
Yoon Suk Jung, Nam Hee Kim, Youngwoo Kim, Dong Il Park
Summary: This study compared the risk of metachronous colorectal neoplasia (CRN) according to adenoma location and found that proximal adenoma was associated with an increased risk of metachronous CRN, but not with an increased risk of metachronous advanced CRN (ACRN).
DIGESTIVE AND LIVER DISEASE
(2022)
Article
Medicine, Research & Experimental
Daniela Jicman (Stan), Elena Niculet, Mihaela Lungu, Cristian Onisor, Laura Rebegea, Carmen Bobeica, Alina Mihaela Elisei, Lucretia Anghel, Alin Laurentiu Tatu
Summary: This study presents a rare case of a patient with a history of rectal malignant tumor who was later diagnosed with advanced nasopharyngeal carcinoma, suggesting potential interactions between the two cancers due to genetic instabilities. Further research is needed on multidisciplinary therapeutic management and early detection of nasopharyngeal cancer.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2021)
Article
Surgery
Wei Liu, Jia-Ming Liu, Kun Wang, Hong-Wei Wang, Bao-Cai Xing
Summary: This study investigated predictive factors for survival outcomes in recurrent colorectal liver metastasis patients. Factors such as primary lymph node positivity, tumor size > 3 cm, early recurrence, RAS gene mutation, and lack of local treatment were identified as independent risk factors for survival outcomes. A nomogram based on these factors showed good predictive ability.
Article
Oncology
Matthias Kelm, Julia Schollbach, Friedrich Anger, Armin Wiegering, Ingo Klein, Christoph-Thomas Germer, Nicolas Schlegel, Volker Kunzmann, Stefan Loeb
Summary: This study found that additive chemotherapy significantly prolonged overall survival and improved 10-year survival rates in patients after curative resection of metachronous colorectal liver metastases. Additive chemotherapy, more than five CRLM, and disease recurrence were identified as independent risk factors for overall survival. Randomized clinical trials are needed to determine optimal chemotherapy regimens for these patients in the future.
Article
Surgery
Hidetoshi Gon, Masahiro Kido, Motofumi Tanaka, Kaori Kuramitsu, Shohei Komatsu, Masahide Awazu, Shinichi So, Hirochika Toyama, Takumi Fukumoto
Summary: Comparing surgical outcomes, it was found that laparoscopic repeat hepatectomy (LRH) was more favorable than open repeat hepatectomy (ORH) in treating patients with contralateral recurrent HCC, showing shorter operation time, less blood loss, similar postoperative complications, and shorter hospital stay.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Jacob Mathias Bech, Thilde Terkelsen, Annette Snejbjerg Bartels, Fabian Coscia, Sophia Doll, Siqi Zhao, Zhaojun Zhang, Nils Brunner, Jan Lindebjerg, Gunvor Iben Madsen, Xiangdong Fang, Matthias Mann, Jose Manuel Afonso Moreira
Summary: By analyzing the proteomic data of resected adenoma samples, researchers found that the proteome can predict the future occurrence of advanced lesions and progression to colorectal cancer several years in advance.
Article
Medicine, General & Internal
Hou-Ying Cheng, Kai-Wen Huang, Jin-Tung Liang, Been-Ren Lin, John Huang, Ji-Shiang Hung, Chi-Ling Chen
Summary: Multi-RFA and hepatectomy provide similar survival benefits for resectable colorectal cancer liver metastases patients, while systemic treatment has inferior outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Oncology
Carlos Delgado-Miguel, Karla Estefania, Maria San Basilio, Francisco Hernandez Oliveros
Summary: This study presents a new method for the treatment of pulmonary metastases in patients with hepatoblastoma. The use of intraoperative indocyanine green (ICG) fluorescence allowed for accurate identification and limited resection of lung parenchyma, leading to improved safety and postoperative respiratory function.