Article
Nursing
Yilong Yang, Meng Cui, Xinxin Zhao, Simeng Wang, Yumei Wang, Xiaohe Wang
Summary: This study found that pain management is crucial for the psycho-spiritual well-being of terminal cancer patients. Effective pain management can reduce depression and improve spiritual well-being. Additionally, positive expectations, especially optimism, are associated with the spiritual well-being of terminal cancer patients. Therefore, we suggest implementing pain management and psychological interventions for terminal cancer patients, while promoting optimism.
Article
Medicine, General & Internal
Helen M. Poole, Bernhard Frank, Emma Begley, Aimee Woods, Andreia Ramos-Silva, Mike Merriman, Roisin McCulough, Catharine Montgomery
Summary: This study aims to investigate the effectiveness and feasibility of reducing high doses of opioids through a tapering protocol, education, and support for patients with chronic pain. The study will randomly allocate patients to either a tapering group or a tapering with support group to assess the impact of these interventions on pain and quality of life.
Article
Clinical Neurology
Madelyne A. Bisby, Shianika S. Chandra, Amelia J. Scott, Joanne Dudeney, Nickolai Titov, Blake F. Dear
Summary: Pain management programs are effective for people with chronic pain. This study found that depression, anxiety, and disability improved rapidly during the first half of an 8-week internet-delivered pain management program, while reductions in pain intensity occurred mainly during the second half of treatment.
Review
Medicine, General & Internal
Sevilay Tumkaya Yilmaz, Anneleen Malfliet, Omer Elma, Tom Deliens, Jo Nijs, Peter Clarys, An De Groef, Iris Coppieters
Summary: Evidence suggests a link between chronic pain and nutrition, and chronic pain in cancer survivors is gaining attention in healthcare. This review emphasizes the importance of incorporating nutrition into chronic pain management for cancer survivors. Dietary interventions may alter pain pathways and mechanisms, providing a potential modality for chronic pain management in this population.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Health Care Sciences & Services
Mohammad Raad, William Omar Contreras Lopez, Alireza Sharafshah, Marjan Assefi, Kai-Uwe Lewandrowski
Summary: This study systematically reviewed the latest research progress in cancer pain management, highlighting personalized medicine as one of the most promising strategies. By utilizing genomic and pharmacokinetic approaches, genes and variants associated with cancer pain can be identified, providing guidance for clinical personalized treatment.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Oncology
Anna Zielinska, Marcin Wlodarczyk, Adam Makaro, Maciej Salaga, Jakub Fichna
Summary: This review focuses on the pathophysiology of CRC-related pain and discusses current pain management strategies. Pain is a common symptom reported by CRC patients, but current methods do not always provide sufficient relief and may cause complications if used improperly. Future treatments should prioritize pain relief and reducing side effects. Recent pharmacological and non-pharmacological developments in CRC treatment are also covered in this article.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2021)
Article
Psychiatry
Alejandro G. Szmulewicz, Brian T. Bateman, Raisa Levin, Krista F. Huybrechts
Summary: The study found that among patients receiving prescription opioids, sedating antipsychotic agents were associated with an increased risk of overdose compared to nonsedating agents. Therefore, caution is necessary when co-prescribing these medications, and choosing a nonsedating agent whenever possible is recommended.
SCHIZOPHRENIA BULLETIN
(2022)
Review
Medicine, General & Internal
Nell Norman-Nott, Negin Hesam-Shariati, Aidan G. Cashin, Michael A. Wewege, Rodrigo R. N. Rizzo, Chelsey R. Wilks, Yann Quide, James McAuley, Sylvia Maria Gustin
Summary: This systematic review aims to quantify the efficacy of emotion-centric interventions for the physical and emotional characteristics of chronic pain. Various forms of psychological treatments will be systematically evaluated and synthesized. The results of this study may inform the development of new emotion-centric interventions for chronic pain.
Article
Oncology
Andrew L. Coveler, Jonathan Mizrahi, Boryana M. Eastman, Smith Jim Apisarnthanarax, Shalini Dalal, Terry McNearney, Shubham Pant
Summary: Pain is prevalent in patients with pancreatic cancer, and its management is crucial to improve quality of life. The multifactorial nature of pain in pancreatic cancer requires a multifaceted approach to alleviate pain and improve patient outcomes. Tumor response to treatment does not eliminate the risk of ongoing cancer-related pain, making pain management in pancreatic cancer challenging.
Article
Medicine, General & Internal
Cecilie Buskbjerg, Mia Skytte O'Toole, Robert Zachariae, Anders Bonde Jensen, Yoon Frederiksen, Christoffer Johansen, Annika von Heymann, Anne Speckens, Maja Johannsen
Summary: This study aims to optimize psychological treatment for breast cancer-related pain by identifying active treatment components. The study uses a 2x3 factorial design and randomizes 192 women with BC-related pain to eight experimental conditions. The primary outcomes are pain intensity and pain interference.
Article
Anesthesiology
John J. Han, Jove H. Graham, Dawn I. Snyder, Thomas Alfieri
Summary: The study suggests that patients using wearable health technology as part of their pain management program may experience positive effects on depression and prescribed medication, although further research is needed to explore the potential impact of WHT on the negative consequences of chronic pain.
CLINICAL JOURNAL OF PAIN
(2022)
Article
Otorhinolaryngology
Shannon M. Nugent, Benjamin J. Morasco, Robert Handley, Daniel Clayburgh, Elizabeth R. Hooker, Linda Ganzini, Sara J. Knight, Jason Chen, Donald R. Sullivan, Christopher G. Slatore
Summary: This study explores the association between precancer mental health and pain, postcancer health services, and the risk of suicidal self-directed violence (SSDV) among head and neck cancer (HNC) survivors. It found that precancer chronic pain or mood disorders, as well as postcancer mental health and substance use disorder treatment, were associated with increased risk of SSDV, while postcancer palliative care was associated with decreased risk. The study highlights the importance of suicide prevention efforts targeting HNC survivors with specific risk factors and the role of palliative care in supportive cancer care.
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2021)
Article
Psychology, Multidisciplinary
Catarina Tome-Pires, Enric Aragones, Concepcion Rambla, German Lopez-Cortacans, Elisabet Sanchez-Rodriguez, Antonia Caballero, Jordi Miro
Summary: This study aimed to explore patients' perceptions of a group-based psychoeducational intervention for the management of chronic musculoskeletal pain and depression. The perceived barriers included lack of motivation, time constraints, pain, depression, ineffectiveness of pain-relief strategies, and activity avoidance. The facilitators were having a supportive family/friends, the positive effects of self-management, high motivation, and being a proactive patient, as well as peer support and identification, the positive effect of sessions, and free expression.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Medicine, General & Internal
Danghan Xu, Zhanbo Yu, Ximin Cai, Jietao Lin, Tengjiao Lin, Jian Sun, Zhaoxi Liu, Yang Cao, Yihan He
Summary: This pragmatic randomised controlled trial aims to evaluate the effectiveness and safety of Fu's subcutaneous needling (FSN) for cancer pain management. 120 eligible patients will be recruited and randomly assigned into two groups, and the primary outcome will be analgesic consumption.
Review
Medicine, General & Internal
Xiaoqin Wang, Grace Martin, Behnam Sadeghirad, Andrea J. Darzi, Rachel J. Couban, Ivan D. Florez, Holly N. Crandon, Elena Kum, Yaping Chang, Meisam Abdar Esfahani, Laxsanaa Sivananthan, Fatemeh Mehrabi, Neil K. Sengupta, Preksha Rathod, Rami Z. Morsi, D. Norman Buckley, Gordon H. Guyatt, Y. Raja Rampersaud, Christopher J. Standaert, Thomas Agoritsas, Jason W. Busse
Summary: This systematic review aims to assess the effectiveness and harms of interventional procedures for chronic, non-cancer spine pain through randomized controlled trials. The study will use network meta-analysis to compare different interventional procedures, evaluate bias risk, and provide evidence-based support for clinical guidance.
Article
Oncology
Jung Hye Kwon, Sun Kyung Baek, Do Yeun Kim, Yu Jung Kim, Myung Ah Lee, Hye Jin Choi, Ja Min Byun, Jin Young Jeong, Sam H. Ahmedzai, Geun-Doo Jang
Summary: This pilot study suggests that the K-SPARC could be a reliable tool for screening palliative care needs among Korean cancer patients, with further validation studies ongoing.
CANCER RESEARCH AND TREATMENT
(2021)
Article
Oncology
In Gyu Hwang, Minsuk Kwon, Jin Won Kim, Se Hyun Kim, Yun-Gyoo Lee, Jin Young Kim, Su-Jin Koh, Yoon Ho Ko, Seong Hoon Shin, Soojung Hong, Tae-Yong Kim, Sun Young Kim, Hyun Jung Kim, Hyo Jung Kim, Myung Ah Lee, Jung Hye Kwon, Yong Sang Hong, Kyung Hee Lee, Sung Hwa Bae, Dong-Hoe Koo, Jee Hyun Kim, In Sook Woo
Summary: Upfront dose reduction (UDR) of palliative chemotherapy is often performed for older adults with metastatic solid cancer, with approximately 60% of patients receiving UDR. Poor performance status (PS) and living without a spouse were identified as predictive factors of UDR. Patients with UDR showed better tolerance to chemotherapy compared to those with standard doses.
Article
Health Care Sciences & Services
Youngmin Park, Sang-Yeon Suh, Sun-Hyun Kim, Jeanno Park, Seok Joon Yoon, Yu Jung Kim, Beodeul Kang, Jung Hye Kwon, Kwonoh Park, David Hui, Hyeon Jeong Kim, Sanghee Lee, Hong-Yup Ahn
Summary: The study developed a one-item screening question to assess the spiritual well-being of advanced cancer inpatients. Results showed that self-rated spirituality and religiosity had better convergence validity than feeling at peace, recommending their use in screening spiritual well-being in patients.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2021)
Article
Health Care Sciences & Services
Jeehee Pyo, Minsu Ock, Mina Lee, Juhee Kim, Jaekyung Cheon, Juhee Cho, Jung Hye Kwon, Hyeyeoung Kim, Hyeon-Su Im, Young Joo Min, Su-Jin Koh
Summary: This study explored additional domains and items of unmet needs among Korean cancer patients, finding that besides the physical symptoms, participants struggled with numbness in their hands and feet and hair loss. Participants emphasized the importance of providing easily understood treatment information and desired to be helpful members of their families and society, showing a holistic approach to evaluating cancer patients' needs.
BMC PALLIATIVE CARE
(2021)
Article
Oncology
Eun Joo Kang, Myung-Ju Ahn, Chan-Young Ock, Keun-Wook Lee, Jung Hye Kwon, Yaewon Yang, Yoon Hee Choi, Min Kyoung Kim, Jun Ho Ji, Tak Yun, Byung-Ho Nam, Sung-Bae Kim, Bhumsuk Keam
Summary: This study conducted the first randomized trial in patients with ACC, showing that axitinib significantly increased the 6-month PFS rate compared with observation. Axitinib arm had longer PFS and a disease control rate of 100%.
CLINICAL CANCER RESEARCH
(2021)
Article
Hematology
Yong-Pyo Lee, Sang Eun Yoon, Yuqin Song, Seok Jin Kim, Dok Hyun Yoon, Tsai-Yun Chen, Young Il Koh, Ka Won Kang, Ho Sup Lee, Kevin Tay Kuang Wei, Soon Thye Lim, Michelle Poon, Cosphiadi Irawan, Weili Zhao, Young Rok Do, Mark Hong Lee, Soo Chin Ng, Won-Sik Lee, Ye Guo, Huilai Zhang, Hye-Jin Kang, Hwan Jung Yun, Hyo Jung Kim, Daryl Tan Chen Lung, Jae-Yong Kwak, Jae Joon Han, Yeung-Chul Mun, Sung Yong Oh, Hyeok Shim, Jung Hye Kwon, Byeong Seok Sohn, Seong Kyu Park, Jae Cheol Jo, Young Hyeh Ko, Zhu Jun, Won Seog Kim
Summary: This study estimated the relative incidence of CTCLs in Asia and presented therapeutic outcomes based on current treatments for advanced CTCLs. Results showed that primary cutaneous ALK-negative anaplastic large cell lymphoma was the most common subtype of CTCLs, and further studies are needed for standard care treatment of advanced or refractory CTCLs.
INTERNATIONAL JOURNAL OF HEMATOLOGY
(2021)
Article
Health Care Sciences & Services
Yusuke Hiratsuka, Sang-Yeon Suh, Sun-Hyun Kim, Shao-Yi Cheng, Seok-Joon Yoon, Su-Jin Koh, Shin Ae Park, Ji-Yeon Seo, Jung Hye Kwon, Jeanno Park, Youngmin Park, Sun Wook Hwang, Eon Sook Lee, Hong-Yup Ahn, David Hui, Ping-Jen Chen, Takashi Yamaguchi, Tatsuya Morita, Satoru Tsuneto, Masanori Mori, Akira Inoue
Summary: This study compared factors associated with spiritual well-being in dying patients across Japan, Korea, and Taiwan, revealing unique factors in each country. Recognizing these unique factors can enhance the quality of palliative care, indicating the importance of cultural considerations in addressing spiritual well-being in end-of-life care.
PALLIATIVE MEDICINE
(2021)
Article
Oncology
Sun Kyung Baek, Hwa Jung Kim, Jung Hye Kwon, Ha Yeon Lee, Young-Woong Won, Yu Jung Kim, Sujin Baik, Hyewon Ryu
Summary: This study investigated the preparation and creation status of six forms required for decisions on life-sustaining treatment for patients at the end-of-life in hospitals. The findings showed a self-determination rate of 31% and an average time interval of 8.6 days from self-determination to implementation of life-sustaining treatment. The creation of these forms often occurs when patients are close to death.
CANCER RESEARCH AND TREATMENT
(2021)
Article
Oncology
Young-Woong Won, Hwa Jung Kim, Jung Hye Kwon, Ha Yeon Lee, Sun Kyung Baek, Yu Jung Kim, Do Yeun Kim, Hyewon Ryu
Summary: The study analyzed the state of life-sustaining treatment decisions in Korea after the enactment of the law, and found that while patients had a high rate of self-determination, there were still issues with the implementation of the law process and variations in advanced medical treatments.
CANCER RESEARCH AND TREATMENT
(2021)
Article
Oncology
Hwa Jung Kim, Yu Jung Kim, Jung Hye Kwon, Young-Woong Won, Ha Yeon Lee, Sun Kyung Baek, Hyewon Ryu, Do Yeun Kim
Summary: Based on the research findings, patients with self-determination were younger, more likely to reside in Seoul or the capital area, had a longer time from cancer diagnosis, were more likely to use hospice, and less likely to use intensive care units.
CANCER RESEARCH AND TREATMENT
(2021)
Article
Health Policy & Services
Sun Hyun Kim, Sang-Yeon Suh, Seok Joon Yoon, Jeanno Park, Yu Jung Kim, Beodeul Kang, Youngmin Park, Jung Hye Kwon, Kwonoh Park, Jung-Young Kim, Hana Choi, Hong-Yup Ahn, Jun Hamano, David Hui
Summary: Surprisingly, the accuracy of the surprise questions and temporal questions were found to be similar. The high specificity of the 7-day surprise question and 7- and 21-day temporal questions suggest they may be useful in ruling in death if positive.
PALLIATIVE & SUPPORTIVE CARE
(2022)
Article
Oncology
Sejin Kim, Bum Jun Kim, Ilhwan Kim, Jung Han Kim, Hee Kyung Kim, Hyewon Ryu, Dae Ro Choi, In Gyu Hwang, Hunho Song, Jung Hye Kwon, Joo Young Jung, Boram Han, Dae Young Zang
Summary: This study evaluated the efficacy and safety of GV1001 in combination with chemotherapy for metastatic colorectal cancer. The results showed that although no clear GV1001-specific immune response was observed, the addition of GV1001 vaccination was associated with modest efficacy outcomes.
Article
Medicine, General & Internal
Eun Joo Kang, Yun-Gyoo Lee, Bhumsuk Keam, Jin-Hyuk Choi, Jin-Soo Kim, Keon Uk Park, Kyoung Eun Lee, Hyo Jung Kim, Keun-Wook Lee, Min Kyoung Kim, Hee Kyung Ahn, Seong Hoon Shin, Jii Bum Lee, Jung Hye Kwon, Hye Ryun Kim, Sung-Bae Kim, Hwan Jung Yun
Summary: Older patients with LA-HNSCC have aggressive tumor characteristics, receive less intensive treatment, and have poorer prognosis.
Fewer older patients are able to complete planned treatments, with some not receiving the full treatment regimen.
Older patients have a lower survival probability and a significantly higher risk of death compared to younger patients.
KOREAN JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Oncology
Yusuke Hiratsuka, Sang-Yeon Suh, Seon-Hye Won, Sun-Hyun Kim, Seok-Joon Yoon, Su-Jin Koh, Jung Hye Kwon, Jeanno Park, Hong-Yup Ahn, Shao-Yi Cheng, Ping-Jen Chen, Takashi Yamaguchi, Tatsuya Morita, Satoru Tsuneto, Masanori Mori, Akira Inoue
Summary: This study investigated the prevalence and severity of symptoms and signs associated with impending death in advanced cancer patients in East Asia. The results showed that there were different primary symptoms and severe symptoms according to the type of cancer. This study can help clinicians recognize specific symptoms and signs in the very end of life.
SUPPORTIVE CARE IN CANCER
(2022)
Review
Oncology
Seung Hun Lee, Jung Hye Kwon, Young-Woong Won, Jung Hun Kang
Summary: Although palliative sedation is common in Western countries, there is limited research on its practice in Korea. Unlike euthanasia, palliative sedation is ethically and legally accepted in Korea. Studies suggest that palliative sedation does not decrease the survival of terminal cancer patients. Shared decision-making and open communication are crucial in the preference for palliative sedation.
CANCER RESEARCH AND TREATMENT
(2022)
