Journal
CURRENT OPINION IN VIROLOGY
Volume 10, Issue -, Pages 47-55Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2014.12.003
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Funding
- Bourse de l'Ecole Norma le Superieure from Faculte Paris Diderot
- Institut Pasteur in Paris, France
- Programme Transversal de Recherche from the Institut Pasteur [437]
- French government program Investissement d'Avenir [ANR-10-LABX-62-IBEID]
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Most viral pathogens that have emerged in humans have originated from various animal species. Emergence is a multistep process involving an initial spill-over of the infectious agent into single individuals and its subsequent dissemination into the human population. Similar to simian immunodeficiency viruses and simian T lymphotropic viruses, simian foamy viruses (SFV) are retroviruses that are widespread among non-human primates and can be transmitted to humans, giving rise to a persistent infection, which seems to be controlled in the case of SFV. In this review, we present current data on the discovery, cross-species transmission, and molecular evolution of SFV in human populations initially infected and thus at risk for zoonotic emergence.
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