Article
Surgery
Katherine E. Hawkins, R. James Valentine, Julie M. Duke, Qi Wang, Amy B. Reed
Summary: Despite the importance of ankle-brachial index (ABI) in the diagnosis and treatment of peripheral arterial disease, the implementation rate is low. This study found that patients who had never undergone ABI measurement experienced a significant decline in functional status after peripheral vascular intervention.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Surgery
Qingwen Kawaji, Chen Dun, Christi Walsh, Rebecca A. Sorber, David P. Stonko, Christopher J. Abularrage, James H. Black, Bruce A. Perler, Martin A. Makary, Caitlin W. Hicks
Summary: This study investigated the association of index atherectomy with reintervention in patients undergoing femoropopliteal peripheral vascular interventions for claudication. The results showed that patients who received index atherectomy had higher rates of PVI reinterventions, and physicians with high use of atherectomy performed more reinterventions. This suggests the need for a critical reevaluation of the appropriateness of using atherectomy as the initial treatment for claudication.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
S. Elissa Altin, Helen Parise, Connie N. Hess, Ning A. Rosenthal, Mark A. Creager, Herbert D. Aronow, Jeptha P. Curtis
Summary: This study evaluated the rates of revascularization and amputation after lower extremity femoropopliteal peripheral vascular intervention (PVI) in patients with intermittent claudication (IC). The 4-year amputation rate following FP PVI was 4.3%, with a major amputation rate of 3.2%. Further investigation is needed to identify risk factors for amputation.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Review
Cardiac & Cardiovascular Systems
Adam A. Behroozian, Joshua A. Beckman
Summary: Peripheral Artery Disease (PAD) is a manifestation of atherosclerosis that can lead to reduced perfusion of the limb and metabolic dysregulation. The classification of asymptomatic PAD is relatively new, and there is a lack of clinical research on therapies for this population, presenting an opportunity for further exploration. Widespread screening for asymptomatic PAD could potentially reduce morbidity and mortality associated with PAD.
PROGRESS IN CARDIOVASCULAR DISEASES
(2021)
Article
Cardiac & Cardiovascular Systems
Andrew W. Gardner, Polly S. Montgomery, Ming Wang, Menglu Liang
Summary: This randomized controlled trial compared the long-term effects of different exercise programs on symptomatic participants with peripheral artery disease. The study found that a long-term home exercise program (HEP) and transitioning from short-term supervised exercise therapy (SET) to HEP (SET/HEP) were both effective in improving peak walking time and exercise time-to-minimum calf muscle oxygen saturation. These improvements were also correlated with each other.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Kallirroi Kalantzi, Nikolaos Tentolouris, Andreas J. Melidonis, Styliani Papadaki, Michail Peroulis, Konstantinos A. Amantos, George Andreopoulos, George I. Bellos, Dimitrios Boutel, Magdalini Bristianou, Dimitrios Chrisis, Nikolaos A. Dimitsikoglou, John Doupis, Chrysoula Georgopoulou, Stergios A. Gkintikas, Styliani Iraklianou, Konstantinos Kanellas, Kalliopi Kotsa, Theocharis Koufakis, Maria Kouroglou, Anastasios G. Koutsovasilis, Leonidas Lanaras, Eirini Liouri, Charalampos Lixouriotis, Akrivi Lykoudi, Efthymia Mandalaki, Evanthia Papageorgiou, Nikolaos Papanas, Spyridon Rigas, Maria I. Stamatelatou, Ioannis Triantafyllidis, Aikaterini Trikkalinou, Aikaterini N. Tsouka, Ourania Zacharopoulou, Christos Zoupas, Ioannis Tsolakis, Alexandros D. Tselepis
Summary: This study demonstrated that adjunctive cilostazol treatment in patients with type 2 diabetes mellitus with symptomatic lower extremity arterial disease may reduce the risk of ischemic events and improve intermittent claudication symptoms without increasing bleeding risk compared to clopidogrel monotherapy.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Multidisciplinary Sciences
Hafizur Rahman, Iraklis I. Pipinos, Jason M. Johanning, Sara A. Myers
Summary: Gait variability in patients with PAD-IC is different from healthy older controls, showing increased variability in knee and hip ranges of motion. Reduced blood flow has a significant impact on gait variability, with ankle showing increased values for temporal structure of variability. A combination of gait variability parameters can accurately identify PAD-IC disease in at least 70% of cases.
Article
Health Care Sciences & Services
Chung-Hsin Yeh, Fung-Chang Sung, Chih-Hsin Muo, Pao-Sheng Yen, Chung Y. Y. Hsu
Summary: A retrospective cohort study found that women with primary dysmenorrhea (PD) have a higher risk of stroke compared to those without dysmenorrhea. The study suggests that women with PD are at increased risk for ischemic stroke.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Pharmacology & Pharmacy
Shigang Lin, Ruoran Lin, Hongkun Zhang, Qingbo Xu, Yangyan He
Summary: This review focuses on the functional changes of peripheral arterial cells and the mechanisms of PAD pathogenesis. It summarizes the progress of current clinical treatment and potential therapeutic methods for PAD, and provides insights for future perspectives.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Joshua A. Beckman, Peter A. Schneider, Michael S. Conte
Summary: Effective revascularization in peripheral artery disease goes beyond just the procedure, requiring understanding of the urgency of revascularization based on the patient's presentation. Recent developments in tools and options such as open surgical bypass have improved outcomes in lower extremity revascularization, even though evidence to guide practice is limited.
CIRCULATION RESEARCH
(2021)
Article
Medicine, General & Internal
Henning Olbrich, Khalaf Kridin, Henner Zirpel, Christian D. Sadik, Patrick Terheyden, Diamant Thaci, RalfJ. Ludwig, Katharina Boch
Summary: This study used the TriNetX platform to investigate medical records of over 120 million patients worldwide, and found that cutaneous lupus erythematosus (CLE) and its subtype chronic discoid lupus erythematosus (DLE) are associated with an increased risk of cardiovascular diseases, particularly thromboembolic events. Rating: 7 out of 10.
Article
Neurosciences
Shijian Chen, Jian Zhang, Xianfu Lu, Gengyu Cen, Yiting Song, Xuhui Deng, Yiju Xie, Liuyu Liu, Qianqian Liu, Junling Huang, Jing Li, Hong Yang, Shengliang Shi, Liya Pan, Zhijian Liang
Summary: This study investigated the clinical features, risk factors, and underlying pathogenesis of cancer related SAH. The results showed that patients with cancer related SAH had poor outcomes, and a decrease in platelet and prolonged prothrombin time were identified as independent risk factors. The joint predictive factor with a cutoff value of 11.719 could serve as a novel biomarker for cancer related SAH.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Barbara Sernek, Rok Kamnikar, Miran Sebestjen, Anja Boc, Vinko Boc
Summary: This study investigated the association between the number of CD34(+) hematopoietic cells in the peripheral blood of patients with peripheral artery disease (PAD) and their functional and atherogenic factors. The results showed that the number of CD34(+) cells was associated with the claudication distance and differed between patients with and without type II diabetes and active smokers, past smokers, and non-smokers.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Medicine, General & Internal
Elizabeth E. Blears, Jessica K. Elias, Christian Tapking, Craig Porter, Victoria G. Rontoyanni
Summary: Supervised resistance training is effective in prolonging walking performance in patients with peripheral artery disease (PAD). However, further exploration is needed to understand the effects of this exercise modality on vascular function and muscle strength.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Ryo Deguchi, Yusuke Katayama, Hoshi Himura, Tetsuro Nishimura, Yuko Nakagawa, Tetsuhisa Kitamura, Shunsuke Tai, Junya Tsujino, Takeshi Shimazu, Yasumitsu Mizobata
Summary: The telephone triage service has a positive impact on the outcomes of patients with cerebrovascular disease, allowing for speedy treatment and reducing medical expenses and disability risks.
FRONTIERS IN PUBLIC HEALTH
(2023)