Article
Clinical Neurology
Krishnapundha Bunyaratavej, Onanong Phokaewvarangkul, Piyanat Wangsawatwong
Summary: The study found a significant difference in directional axis error along the y axis between first and second electrode placements in the STN subgroup, but its magnitude is well below the clinically significant threshold.
BRITISH JOURNAL OF NEUROSURGERY
(2021)
Article
Clinical Neurology
Yu-Xi Wu, Wei Xiang, Jia-Jing Wang, Xiao-Ming Liu, Dong-Ye Yi, Han Tian, Hong-Yang Zhao, Xiao-Bing Jiang, Peng Fu
Summary: The modified DP procedure for DBS surgery showed better outcomes in reducing brain shift, decreasing CSF leakage, and improving electrode placement accuracy compared to the standard DI procedure.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Shams Ribault, Emile Simon, Julien Berthiller, Gustavo Polo, Adelaide Nunes, Andrei Brinzeu, Patrick Mertens, Teodor Danaila, Stephane Thobois, Chloe Laurencin
Summary: The study found that robot-assisted and frame-based stereotactic deep brain stimulation of the subthalamic nucleus in Parkinson's disease patients provide similar clinical outcomes and accuracy of electrode placement.
ACTA NEUROCHIRURGICA
(2021)
Article
Neurosciences
Shanshan Mei, Kaijia Yu, Zhiwei Ren, Yongsheng Hu, Song Guo, Yongjie Li, Jianyu Li
Summary: The study found that awake frameless robot-assisted DBS surgery was comparable to the conventional frame-based technique in terms of accuracy and precision for leads implantation, with no significant difference between the two groups.
Article
Multidisciplinary Sciences
Patrick Pearce, Kristian Bulluss, San San Xu, Boaz Kim, Marko Milicevic, Thushara Perera, Wesley Thevathasan
Summary: The study evaluated the accuracy of STN-DBS electrode implantation in PD patients and found that electrode location errors were highly variable. Factors such as brain shift and microelectrode trajectory shifts did not significantly impact location error. The study suggests that more accurate methods are needed for implanting STN-DBS electrodes.
Article
Multidisciplinary Sciences
Guglielmo Iess, Giulio Bonomo, Vincenzo Levi, Domenico Aquino, Edvin Zekaj, Federica Mezza, Domenico Servello
Summary: Optimal lead positioning is crucial for Deep Brain Stimulation (DBS) outcome, and although directional leads show potential, it remains debatable how factors like operative time and the use of MER contribute to the formation of pneumocephalus. This study analyzed data from 94 DBS patients and found no significant increase in pneumocephalus risk with the use of MER. Unilateral implants and specific targets were associated with different volumes of pneumocephalus.
SCIENTIFIC REPORTS
(2023)
Article
Clinical Neurology
Tuan Anh Pham, Phuong Duy Dao, Lam Thanh Nguyen, Thang Viet Le, Nghia Thanh Vo, Tai Ngoc Tran, Anh Minh Nguyen, Thuy Anh Diem Nguyen, Khang Thai Binh Le
Summary: This study evaluated the accuracy of subthalamic nucleus (STN)-DBS electrode implantation technique for treating Parkinson's Disease (PD) at Nguyen Tri Phuong Hospital and University Medical Center in Vietnam. The results showed that the technique was accurate with acceptable error. Factors such as subdural air volume, cortical shift, and intracranial electrode bending were found to be correlated with accuracy. Further clinical trials are needed to compare the influencing factors on electrode implantation accuracy.
WORLD NEUROSURGERY
(2023)
Article
Engineering, Biomedical
Ma Luo, Saramati Narasimhan, Paul S. Larson, Alastair J. Martin, Peter E. Konrad, Michael Miga
Summary: This study utilized a multi-physics analysis framework to investigate the impact of intraoperative brain shift on neural pathways during DBS surgery. The results showed that brain shift induced changes in neural pathways and a strong correlation was found between shift and intended neural pathway recruitment. The study also determined a critical threshold for shift affecting neural activation.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Multidisciplinary Sciences
Michael Rosenblum, Arkady Pikovsky, Andrea A. Kuehn, Johannes L. Busch
Summary: The computation of instantaneous phase and amplitude using the Hilbert Transform is a powerful tool in data analysis, however, it is not suitable for causal estimation due to the requirement of knowledge of past and future signals. Real-time estimation of phase and amplitude is important in various fields, such as neuroscience. Three causal algorithms that do not rely on the Hilbert Transform but utilize synchronization and resonance were discussed and compared in this study, with their performance tested on synthetic data and accelerometer tremor measurements as well as Parkinsonian patient's brain activity.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Changgeng He, Feng Zhang, Linze Li, Changqing Jiang, Luming Li
Summary: This study identified key factors in post-implantation localization of DBS lead and described a localization method using individual template to reduce deviation. Correcting the reconstruction direction relative to the lead direction, rather than the magnetic field, and using the relationship between magnetic field angle and deviation error, led to a reduction in mean localization error, making direct localization of DBS lead using MR images feasible.
FRONTIERS IN NEUROSCIENCE
(2021)
Review
Clinical Neurology
Katharine R. Phillips, Charles E. Mackel, Ron L. Alterman
Summary: This study compared the Leksell G frame with the new Leksell Vantage stereotactic headframe in deep brain stimulation (DBS) procedures and demonstrated the superior targeting accuracy of the Vantage frame compared to the traditional G frame.
OPERATIVE NEUROSURGERY
(2023)
Article
Engineering, Biomedical
Thibault Martin, Greydon Gilmore, Claire Haegelen, Pierre Jannin, John S. H. Baxter
Summary: This study presented a simple algorithm that allows for early termination of MER data collection when sufficient confidence is reached in the underlying neural network. The Bayesian model of the underlying network's certainty outperformed other configurations and showed potential to improve efficiency in DBS electrode implantation.
INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
(2021)
Article
Neurosciences
Bin Wu, Yuting Ling, Changming Zhang, Jiakun Xu, Chao Yang, Nan Jiang, Ling Chen, Jinlong Liu
Summary: This retrospective study analyzed patients who underwent deep brain stimulation surgery and found that peri-electrode edema is common and the use of steroids can reduce its occurrence and extent.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Neurosciences
Jennifer A. MacLean, Diana Ferman, Jason K. Chu, Mark A. Liker, Terence D. Sanger
Summary: This study presents a case of a patient with Tourette syndrome who experienced significant improvement in symptoms with the placement and stimulation of permanent electrodes, although complete resolution was not achieved. The findings suggest that simultaneous stimulation at multiple patient-specific targets could be effective in controlling Tourette symptomatology, but further research is needed to confirm this.
Article
Clinical Neurology
Massimo Piacentino, Giacomo Beggio, Oriela Rustemi, Giampaolo Zambon, Manuela Pilleri, Fabio Raneri
Summary: The study compared the accuracy and treatment outcomes of two techniques for deep brain stimulation electrode placement, with results showing that the modified technique significantly reduced errors in electrode placement compared to the standard technique, although the clinical difference between the two was not significant.
ACTA NEUROCHIRURGICA
(2021)
Article
Clinical Neurology
Meher R. Juttukonda, Giulia Franco, Dario J. Englot, Ya-Chen Lin, Kalen J. Petersen, Paula Trujillo, Peter Hedera, Bennett A. Landman, Hakmook Kang, Manus J. Donahue, Peter E. Konrad, Benoit M. Dawant, Daniel O. Claassen
Article
Clinical Neurology
Chengyuan Wu, Walter J. Jermakowicz, Srijata Chakravorti, Iahn Cajigas, Ashwini D. Sharan, Jonathan R. Jagid, Caio M. Matias, Michael R. Sperling, Robert Buckley, Andrew Ko, Jeffrey G. Ojemann, John W. Miller, Brett Youngerman, Sameer A. Sheth, Guy M. McKhann, Adrian W. Laxton, Daniel E. Couture, Gautam S. Popli, Alexander Smith, Ashesh D. Mehta, Allen L. Ho, Casey H. Halpern, Dario J. Englot, Joseph S. Neimat, Peter E. Konrad, Elliot Neal, Fernando L. Vale, Kathryn L. Holloway, Ellen L. Air, Jason Schwalb, Benoit M. Dawant, Pierre-Francois D'Haese
Article
Medicine, Research & Experimental
Mya Caryn Schiess, Sam Eldabe, Peter Konrad, Lisa Molus, Robert Spencer, Katherine Stromberg, Todd Weaver, Robert Plunkett
Article
Clinical Neurology
Danika L. Paulo, Alexander M. Lopez, Walter J. Jermakowicz, Hong Yu, Hamid Shah, Peter E. Konrad, Dario J. Englot
WORLD NEUROSURGERY
(2020)
Article
Clinical Neurology
Alexander M. Lopez, Paula Trujillo, Adreanna B. Hernandez, Ya-Chen Lin, Hakmook Kang, Bennett A. Landman, Dario J. Englot, Benoit M. Dawant, Peter E. Konrad, Daniel O. Claassen
MOVEMENT DISORDERS
(2020)
Article
Clinical Neurology
Jeffrey R. Binder, Jia-Qing Tong, Sara B. Pillay, Lisa L. Conant, Colin J. Humphries, Manoj Raghavan, Wade M. Mueller, Robyn M. Busch, Linda Allen, William L. Gross, Christopher T. Anderson, Chad E. Carlson, Mark J. Lowe, John T. Langfitt, Madalina E. Tivarus, Daniel L. Drane, David W. Loring, Monica Jacobs, Victoria L. Morgan, Jane B. Allendorfer, Jerzy P. Szaflarski, Leonardo Bonilha, Susan Bookheimer, Thomas Grabowski, Jennifer Vannest, Sara J. Swanson
Article
Clinical Neurology
Debbie A. Masemer, Hong Yu, Peter E. Konrad, Dario J. Englot
JOURNAL OF NEUROSCIENCE NURSING
(2020)
Article
Clinical Neurology
Mallory L. Hacker, Maxim Turchan, Lauren E. Heusinkveld, Amanda D. Currie, Sarah H. Millan, Anna L. Molinari, Peter E. Konrad, Thomas L. Davis, Fenna T. Phibbs, Peter Hedera, Kevin R. Cannard, Li Wang, David Charles
Article
Medicine, Research & Experimental
Richard B. North, Peter E. Konrad, Jack W. Judy, Andrew J. Ries, Robert Stevenson
Summary: The majority of clinicians support the development of standardized connectors for spinal cord stimulation and other neurostimulation therapies, as revealed through an online survey. This would reduce the need for adapters and facilitate component interchange when necessary.
Article
Clinical Neurology
Daniel I. Wolfson, Jordan A. Magarik, Saniya S. Godil, Hamid M. Shah, Joseph S. Neimat, Peter E. Konrad, Dario J. Englot
Summary: Bone cement cranioplasty significantly reduces the incidence of postoperative cerebrospinal fluid leak and other complications following microvascular decompression surgery. Noncement closure was identified as the only independent predictor of CSF leak in this study. Modifiable risk factors, such as body mass index, were not associated with the development of CSF leak.
JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE
(2021)
Article
Clinical Neurology
Mallory L. Hacker, Michael G. Tramontana, Kian Pazira, Jacqueline C. Meystedt, Maxim Turchan, Kelly A. Harper, Run Fan, Fei Ye, Thomas L. Davis, Peter E. Konrad, David Charles
Summary: This study examined the long-term neuropsychological outcomes of deep brain stimulation (DBS) in early-stage Parkinson's disease (PD) patients. The results showed no significant differences between DBS plus optimal drug therapy (DBS + ODT) and optimal drug therapy alone (ODT) groups after five and eleven years. However, there was a significant decline in cognitive processing speed and motor control for all PD patients. More research is needed to understand the long-term effects of early DBS on neuropsychological outcomes in PD.
PARKINSONISM & RELATED DISORDERS
(2023)
Article
Neurosciences
Manish Ranjan, Pranab Kumar, Peter Konrad, Ali R. Rezai
Proceedings Paper
Computer Science, Artificial Intelligence
Ma Luo, Paul S. Larson, Alastair J. Martin, Peter E. Konrad, Michael I. Miga
MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2019, PT V
(2019)
Proceedings Paper
Engineering, Biomedical
Srijata Chakravorti, Rui Li, William Rodriguez, Robert Shults, Ashwini Sharan, Dario J. Englot, Peter E. Konrad, Pierre-Francois D'Haese, Benoit M. Dawant
MEDICAL IMAGING 2019: IMAGE-GUIDED PROCEDURES, ROBOTIC INTERVENTIONS, AND MODELING
(2019)
Proceedings Paper
Engineering, Biomedical
Camilo Bermudez, William Rodriguez, Yuankai Huo, Allison E. Hainline, Rui Li, Robert Shults, Pierre D. D'Haese, Peter E. Konrad, Benoit M. Dawant, Bennett A. Landman
MEDICAL IMAGING 2019: IMAGE PROCESSING
(2019)
