Leptin Signaling Is Required for Augmented Therapeutic Properties of Mesenchymal Stem Cells Conferred by Hypoxia Preconditioning

Severe hypoxia exerts parallel and cell-specific regulation of gene expression and alternative splicing in human mesenchymal stem cells

(2014) Xinyang Hu et al.   BMC GENOMICS

Leptin Mediates Tumor-Stromal Interactions That Promote the Invasive Growth of Breast Cancer Cells

(2012) I. Barone et al.   CANCER RESEARCH

Update on cardiac stem cell therapy in heart failure

(2012) Peter Donndorf et al.   CURRENT OPINION IN CARDIOLOGY

Towards regenerative therapy for cardiac disease

(2012) Leon M Ptaszek et al.   LANCET

Leptin increases HER2 protein levels through a STAT3-mediated up-regulation of Hsp90 in breast cancer cells

(2012) Cinzia Giordano et al.   Molecular Oncology

The Role of SDF-1-CXCR4/CXCR7 Axis in the Therapeutic Effects of Hypoxia-Preconditioned Mesenchymal Stem Cells for Renal Ischemia/Reperfusion Injury

(2012) Hongbao Liu et al.   PLoS One

Hypoxic Preconditioning Improves Survival of Cardiac Progenitor Cells: Role of Stromal Cell Derived Factor-1α–CXCR4 Axis

(2012) Fengdi Yan et al.   PLoS One

Hypoxic preconditioning enhances bone marrow mesenchymal stem cell migration via Kv2.1 channel and FAK activation

(2011) Xinyang Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche

(2011) Toshio Suda et al.   Cell Stem Cell

Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications

(2011) Angela Burgess et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease

(2011) Ruenn Chai Lai et al.   Regenerative Medicine

Upregulation of leptin-receptor in placental cells by Hypoxia

(2011) Daniela Klaffenbach et al.   REGULATORY PEPTIDES

Bone Marrow Cell Injection for Chronic Myocardial Ischemia: The Past and the Future

(2011) Jan van Ramshorst et al.   Journal of Cardiovascular Translational Research

Derivation of multipotent nestin+/CD271−/STRO-1− mesenchymal-like precursors from human embryonic stem cells in chemically defined conditions

(2011) Rongrong Wu et al.   Human Cell

Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore

(2010) Christopher C. T. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice

(2010) Kenneth R. McGaffin et al.   CARDIOVASCULAR RESEARCH

Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFκB/HIF-1α activation

(2010) Ruben R. Gonzalez-Perez et al.   CELLULAR SIGNALLING

The potential of statin and stromal cell-derived factor-1 to promote angiogenesis

(2010) Hong Yu et al.   Cell Adhesion & Migration

Leptin attenuates cardiac apoptosis after chronic ischaemic injury

(2009) Kenneth R. McGaffin et al.   CARDIOVASCULAR RESEARCH

Hypoxic Preconditioning Enhances the Benefit of Cardiac Progenitor Cell Therapy for Treatment of Myocardial Infarction by Inducing CXCR4 Expression

(2009) Yao Liang Tang et al.   CIRCULATION RESEARCH

STAT3 inhibits the degradation of HIF-1α by pVHL-mediated ubiquitination

(2009) Joo Eun Jung et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Transcriptional signature of human adipose tissue-derived stem cells (hASCs) preconditioned for chondrogenesis in hypoxic conditions

(2009) L. Pilgaard et al.   EXPERIMENTAL CELL RESEARCH

Extracellular calcium increases CXCR4 expression on bone marrow-derived cells and enhances pro-angiogenesis therapy

(2009) Quiling Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Increased expression of CXCR4 and integrin αM in hypoxia-preconditioned cells contributes to improved cell retention and angiogenic potency

(2009) Masayuki Kubo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Signal transducer and activator of transcription 3–stimulated hypoxia inducible factor-1α mediates estrogen receptor-α–induced mesenchymal stem cell vascular endothelial growth factor production

(2009) Meijing Wang et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Leptin Enhances the Recruitment of Endothelial Progenitor Cells Into Neointimal Lesions After Vascular Injury by Promoting Integrin-Mediated Adhesion

(2008) Marco R. Schroeter et al.   CIRCULATION RESEARCH

Leptin protects H9c2 rat cardiomyocytes from H2O2-induced apoptosis

(2008) Megumi Eguchi et al.   FEBS Journal

Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis

(2008) Xinyang Hu et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Signal Transducer and Activator of Transcription 3 Is Required for Hypoxia-Inducible Factor-1  RNA Expression in Both Tumor Cells and Tumor-Associated Myeloid Cells

(2008) G. Niu et al.   MOLECULAR CANCER RESEARCH