Concise Review: Genetic Dissection of Hypoxia Signaling Pathways in Normal and Leukemic Stem Cells
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Concise Review: Genetic Dissection of Hypoxia Signaling Pathways in Normal and Leukemic Stem Cells
Authors
Keywords
-
Journal
STEM CELLS
Volume 32, Issue 6, Pages 1390-1397
Publisher
Wiley
Online
2014-02-05
DOI
10.1002/stem.1657
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hif-2 is not essential for cell-autonomous hematopoietic stem cell maintenance
- (2013) A. V. Guitart et al. BLOOD
- Multimodal imaging reveals structural and functional heterogeneity in different bone marrow compartments: functional implications on hematopoietic stem cells
- (2013) F. Lassailly et al. BLOOD
- HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress
- (2013) R. P. Singh et al. BLOOD
- Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
- (2013) Keiyo Takubo et al. Cell Stem Cell
- HIF-2α Protects Human Hematopoietic Stem/Progenitors and Acute Myeloid Leukemic Cells from Apoptosis Induced by Endoplasmic Reticulum Stress
- (2013) Kevin Rouault-Pierre et al. Cell Stem Cell
- What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
- (2013) J.-A. Losman et al. GENES & DEVELOPMENT
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Isocitrate dehydrogenase mutations in leukemia
- (2013) Anna Sophia McKenney et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction
- (2013) P Storti et al. LEUKEMIA
- CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance
- (2013) Adam Greenbaum et al. NATURE
- Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
- (2013) Lei Ding et al. NATURE
- Erratum: Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment
- (2013) César Nombela-Arrieta et al. NATURE CELL BIOLOGY
- (R)-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
- (2013) J.-A. Losman et al. SCIENCE
- HIF1α is a regulator of hematopoietic progenitor and stem cell development in hypoxic sites of the mouse embryo
- (2013) Parisa Imanirad et al. Stem Cell Research
- HIF-1 deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency
- (2012) J. Du et al. BLOOD
- Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells
- (2012) F. Kocabas et al. BLOOD
- Pharmacologic stabilization of HIF-1 increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation
- (2012) C. E. Forristal et al. BLOOD
- HIF1 is required for survival maintenance of chronic myeloid leukemia stem cells
- (2012) H. Zhang et al. BLOOD
- The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO
- (2012) Erinn B. Rankin et al. CELL
- HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation
- (2012) M He et al. CELL DEATH AND DIFFERENTIATION
- HIF-1α protein is upregulated in HIF-2α depleted cells via enhanced translation
- (2012) Kathrin Schulz et al. FEBS LETTERS
- Hypoxia-inducible factor-1α expression indicates poor prognosis in myelodysplastic syndromes
- (2012) Hongyan Tong et al. LEUKEMIA & LYMPHOMA
- Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
- (2012) Peppi Koivunen et al. NATURE
- Endothelial and perivascular cells maintain haematopoietic stem cells
- (2012) Lei Ding et al. NATURE
- Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
- (2012) K. Sarkar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1 -dependent function
- (2012) Y. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Passing the baton: the HIF switch
- (2012) Mei Yee Koh et al. TRENDS IN BIOCHEMICAL SCIENCES
- High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
- (2011) J. Schodel et al. BLOOD
- Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies
- (2011) Yin Wang et al. Cell Stem Cell
- Embryonic origin of the adult hematopoietic system: advances and questions
- (2011) A. Medvinsky et al. DEVELOPMENT
- The hematopoietic stem cell niche
- (2011) Dongsu Park Frontiers in Bioscience-Landmark
- The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
- (2010) Tugba Simsek et al. Cell Stem Cell
- Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
- (2010) Keiyo Takubo et al. Cell Stem Cell
- Hypoxia mediates low cell-cycle activity and increases the proportion of long-term–reconstituting hematopoietic stem cells during in vitro culture
- (2010) Pernilla Eliasson et al. EXPERIMENTAL HEMATOLOGY
- Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells
- (2010) S Colla et al. LEUKEMIA
- Insights into the stem cells of chronic myeloid leukemia
- (2010) I Sloma et al. LEUKEMIA
- Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming
- (2010) F Zhao et al. ONCOGENE
- The humanHIF(hypoxia-inducible factor)-3α gene is a HIF-1 target gene and may modulate hypoxic gene induction
- (2009) Tetsuhiro Tanaka et al. BIOCHEMICAL JOURNAL
- Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
- (2009) Massimiliano Mazzone et al. CELL
- Cited2 Is an Essential Regulator of Adult Hematopoietic Stem Cells
- (2009) Kamil R. Kranc et al. Cell Stem Cell
- Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
- (2009) David R. Mole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis
- (2009) X. Xia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
- (2008) Stuart H. Orkin et al. CELL
- Hypoxia-inducible Transcription Factor-2α in Endothelial Cells Regulates Tumor Neovascularization through Activation of Ephrin A1
- (2008) Toshiharu Yamashita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
- Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins
- (2007) K. Takeda et al. BLOOD
- Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
- (2007) Y. A. Minamishima et al. BLOOD
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search