Lmo2Induces Hematopoietic Stem Cell-Like Features in T-Cell Progenitor Cells Prior to Leukemia

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL

(2011) J. Tatarek et al.   BLOOD

Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies

(2011) L. M. Treanor et al.   BLOOD

E2F2 represses cell cycle regulators to maintain quiescence

(2011) Arantza Infante et al.   CELL CYCLE

Hes1 Is a Critical but Context-Dependent Mediator of Canonical Notch Signaling in Lymphocyte Development and Transformation

(2010) Agnieszka A. Wendorff et al.   IMMUNITY

Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells

(2010) LiQi Li et al.   NATURE IMMUNOLOGY

A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients

(2010) S H Oram et al.   ONCOGENE

An Early T Cell Lineage Commitment Checkpoint Dependent on the Transcription Factor Bcl11b

(2010) L. Li et al.   SCIENCE

The Lmo2 Oncogene Initiates Leukemia in Mice by Inducing Thymocyte Self-Renewal

(2010) M. P. McCormack et al.   SCIENCE

Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors

(2009) Ying Cai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adult Hematopoietic Stem and Progenitor Cells Require Either Lyl1 or Scl for Survival

(2009) George P. Souroullas et al.   Cell Stem Cell

Murine Leukemias with Retroviral Insertions at Lmo2 Are Predictive of the Leukemias Induced in SCID-X1 Patients Following Retroviral Gene Therapy

(2009) Utpal P. Davé et al.   PLoS Genetics

Resistance of mature T cells to oncogene transformation

(2008) S. Newrzela et al.   BLOOD

RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays

(2008) J. C. Marioni et al.   GENOME RESEARCH

DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma

(2008) D F Peng et al.   GUT

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

(2008) Salima Hacein-Bey-Abina et al.   JOURNAL OF CLINICAL INVESTIGATION

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

(2008) C. G. Mullighan et al.   SCIENCE