Tumorigenic Potential of miR-18A* in Glioma Initiating Cells Requires NOTCH-1 Signaling

The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network

(2011) M Fareh et al.   CELL DEATH AND DIFFERENTIATION

CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors

(2010) Cristina Patru et al.   BMC CANCER

Molecular characterisation of side population cells with cancer stem cell-like characteristics in small-cell lung cancer

(2010) C D Salcido et al.   BRITISH JOURNAL OF CANCER

A Hierarchy of Self-Renewing Tumor-Initiating Cell Types in Glioblastoma

(2010) Ruihuan Chen et al.   CANCER CELL

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Glioma Cell Populations Grouped by Different Cell Type Markers Drive Brain Tumor Growth

(2010) Lars Prestegarden et al.   CANCER RESEARCH

Somatic cell reprogramming control: Signaling pathway modulation versus transcription factor activities

(2010) Frederic Lluis et al.   CELL CYCLE

NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53

(2010) Marie Zbinden et al.   EMBO JOURNAL

Notch inhibition by the ligand Delta-Like 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis

(2010) Gavin Chapman et al.   HUMAN MOLECULAR GENETICS

A cell autonomous role for the Notch ligand Delta-like 3 in αβ T-cell development

(2010) Gerard F Hoyne et al.   IMMUNOLOGY AND CELL BIOLOGY

Sox1 Maintains the Undifferentiated State of Cortical Neural Progenitor Cells via the Suppression of Prox1-Mediated Cell Cycle Exit and Neurogenesis

(2010) Maximilianos Elkouris et al.   STEM CELLS

The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras

(2009) Wing Pui Tsang et al.   CARCINOGENESIS

Phosphorylation of the Human MicroRNA-Generating Complex Mediates MAPK/Erk Signaling

(2009) Zain Paroo et al.   CELL

Dynamic distribution and stem cell characteristics of Sox1-expressing cells in the cerebellar cortex

(2009) Joelle Alcock et al.   CELL RESEARCH

Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer

(2009) Motoko Seto et al.   MOLECULAR CARCINOGENESIS

Two major gate-keepers in the self-renewal of neural stem cells: Erk1/2 and PLCγ1 in FGFR signaling

(2009) Jin-A Lee et al.   Molecular Brain

Molecular genetic analysis of FGFR1 signalling reveals distinct roles of MAPK and PLCγ1 activation for self-renewal of adult neural stem cells

(2009) Dengke K Ma et al.   Molecular Brain

Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells

(2008) Shu Takakura et al.   CANCER SCIENCE

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

(2008) Anastasia Murat et al.   JOURNAL OF CLINICAL ONCOLOGY

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE

IDENTIFICATION OF A2B5+CD133− TUMOR-INITIATING CELLS IN ADULT HUMAN GLIOMAS

(2008) Alfred T. Ogden et al.   NEUROSURGERY

CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

(2007) Jian Wang et al.   INTERNATIONAL JOURNAL OF CANCER