Concise Review: Pursuing Self-Renewal and Pluripotency with the Stem Cell Factor Nanog

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency

(2013) Yael Costa et al.   NATURE

Regulation of Pluripotency and Cellular Reprogramming by the Ubiquitin-Proteasome System

(2012) Shannon M. Buckley et al.   Cell Stem Cell

Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells

(2012) Nicola Festuccia et al.   Cell Stem Cell

The Histone Acetyltransferase MOF Is a Key Regulator of the Embryonic Stem Cell Core Transcriptional Network

(2012) Xiangzhi Li et al.   Cell Stem Cell

Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal

(2012) Graziano Martello et al.   Cell Stem Cell

Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming

(2012) M. Percharde et al.   GENES & DEVELOPMENT

Surf the Post-translational Modification Network of p53 Regulation

(2012) Bo Gu et al.   International Journal of Biological Sciences

Fibroblast Growth Factor Receptor 2 Homodimerization Rapidly Reduces Transcription of the Pluripotency GeneNanogwithout Dissociation of Activating Transcription Factors

(2012) Katherine E. Santostefano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Nuclear Receptor Coactivator 3 (Ncoa3) in Pluripotency Maintenance

(2012) Zhaoting Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanog Increases Focal Adhesion Kinase (FAK) Promoter Activity and Expression and Directly Binds to FAK Protein to Be Phosphorylated

(2012) Baotran Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of ground-state pluripotency by allelic regulation of Nanog

(2012) Yusuke Miyanari et al.   NATURE

Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity

(2012) Ben D. MacArthur et al.   NATURE CELL BIOLOGY

Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming

(2012) M. Fidalgo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-β-Superfamily Signaling Regulates Embryonic Stem Cell Heterogeneity: Self-Renewal as a Dynamic and Regulated Equilibrium

(2012) Katherine E. Galvin-Burgess et al.   STEM CELLS

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

Epigenetic regulation ofNanogexpression by Ezh2 in pluripotent stem cells

(2011) Aranzazu Villasante et al.   CELL CYCLE

Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain

(2011) T. W. Theunissen et al.   DEVELOPMENT

Alternative Splicing Produces Nanog Protein Variants with Different Capacities for Self-renewal and Pluripotency in Embryonic Stem Cells

(2011) Satyabrata Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Zfp281 Functions as a Transcriptional Repressor for Pluripotency of Mouse Embryonic Stem Cells

(2011) Miguel Fidalgo et al.   STEM CELLS

PEST Motif Sequence Regulating Human NANOG for Proteasomal Degradation

(2011) Suresh Ramakrishna et al.   STEM CELLS AND DEVELOPMENT

Characterization of Danio rerio Nanog and Functional Comparison to Xenopus Vents

(2011) Maximilian Schuff et al.   STEM CELLS AND DEVELOPMENT

Axolotl Nanog activity in mouse embryonic stem cells demonstrates that ground state pluripotency is conserved from urodele amphibians to mammals

(2010) J. E. Dixon et al.   DEVELOPMENT

Kruppel-like Factor 4 (Klf4) Prevents Embryonic Stem (ES) Cell Differentiation by Regulating Nanog Gene Expression

(2010) Peilin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation stabilizes Nanog by promoting its interaction with Pin1

(2010) M. Moretto-Zita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation

(2010) N. Salomonis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide gain-of-function screen identifies novel regulators of pluripotency

(2010) Ramzey Abujarour et al.   STEM CELLS

The Pluripotency Regulator Zic3 Is a Direct Activator of the Nanog Promoter in ESCs

(2010) Linda Shushan Lim et al.   STEM CELLS

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

Cross-regulation of the Nanog and Cdx2 promoters

(2009) Lingyi Chen et al.   CELL RESEARCH

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

(2009) J. Rossant et al.   DEVELOPMENT

Activin/Nodal signalling maintains pluripotency by controlling Nanog expression

(2009) L. Vallier et al.   DEVELOPMENT

Satb1 and Satb2 regulate embryonic stem cell differentiation andNanogexpression

(2009) Fabio Savarese et al.   GENES & DEVELOPMENT

A Positive Regulatory Role for the mSin3A-HDAC Complex in Pluripotency through Nanog and Sox2

(2009) Gretchen A. Baltus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronan-CD44 Interaction with Protein Kinase Cϵ Promotes Oncogenic Signaling by the Stem Cell Marker Nanog and the Production of MicroRNA-21, Leading to Down-regulation of the Tumor Suppressor Protein PDCD4, Anti-apoptosis, and Chemotherapy Resistance in Breast Tumor Cells

(2009) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

(2009) Hitoshi Niwa et al.   NATURE

Direct cell reprogramming is a stochastic process amenable to acceleration

(2009) Jacob Hanna et al.   NATURE

Molecular Characterization of the Human NANOG Protein

(2009) David F. Chang et al.   STEM CELLS

KLF4 and PBX1 Directly RegulateNANOGExpression in Human Embryonic Stem Cells

(2009) Ken Kwok-Keung Chan et al.   STEM CELLS

The pluripotency rheostat Nanog functions as a dimer

(2008) Nicholas P. Mullin et al.   BIOCHEMICAL JOURNAL

Capturing Pluripotency

(2008) Jose Silva et al.   CELL

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

(2008) Jonghwan Kim et al.   CELL

NANOG Is a Direct Target of TGFβ/Activin-Mediated SMAD Signaling in Human ESCs

(2008) Ren-He Xu et al.   Cell Stem Cell

Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells

(2008) M. F. Cole et al.   GENES & DEVELOPMENT

Estrogen-Related Receptor Beta Interacts with Oct4 To Positively Regulate Nanog Gene Expression

(2008) D. L. C. van den Berg et al.   MOLECULAR AND CELLULAR BIOLOGY

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

(2008) Jiancong Liang et al.   NATURE CELL BIOLOGY

Requirement of Nanog dimerization for stem cell self-renewal and pluripotency

(2008) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of Primordial Germ Cells from Differentiating Human Embryonic Stem Cells

(2008) Katarzyna Tilgner et al.   STEM CELLS

Zfp143 RegulatesNanogThrough Modulation of Oct4 Binding

(2008) Xi Chen et al.   STEM CELLS

The Transcription Factor Zfp281 Controls Embryonic Stem Cell Pluripotency by Direct Activation and Repression of Target Genes

(2008) Zheng-Xu Wang et al.   STEM CELLS

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

(2008) Jose Silva et al.   PLOS BIOLOGY

Crystal Structure and DNA Binding of the Homeodomain of the Stem Cell Transcription Factor Nanog

(2007) Ralf Jauch et al.   JOURNAL OF MOLECULAR BIOLOGY