Concise Review: Genetically Engineered Stem Cell Therapy Targeting Angiogenesis and Tumor Stroma in Gastrointestinal Malignancy

Mesenchymal stem cells engineered for cancer therapy

(2011) Khalid Shah   ADVANCED DRUG DELIVERY REVIEWS

Selective Targeting of Genetically Engineered Mesenchymal Stem Cells to Tumor Stroma Microenvironments Using Tissue-Specific Suicide Gene Expression Suppresses Growth of Hepatocellular Carcinoma

(2011) Hanno Niess et al.   ANNALS OF SURGERY

Targeting the ANG2/TIE2 Axis Inhibits Tumor Growth and Metastasis by Impairing Angiogenesis and Disabling Rebounds of Proangiogenic Myeloid Cells

(2011) Roberta Mazzieri et al.   CANCER CELL

Stem Cell Based Cancer Gene Therapy

(2011) Marina Cihova et al.   MOLECULAR PHARMACEUTICS

Image-guided, Tumor Stroma-targeted 131I Therapy of Hepatocellular Cancer After Systemic Mesenchymal Stem Cell-mediated NIS Gene Delivery

(2011) Kerstin Knoop et al.   MOLECULAR THERAPY

Ex vivo gene transfer and correction for cell-based therapies

(2011) Luigi Naldini   NATURE REVIEWS GENETICS

Mesenchymal Stem Cell-Mediated Delivery of the Sodium Iodide Symporter Supports Radionuclide Imaging and Treatment of Breast Cancer

(2011) Roisin M. Dwyer et al.   STEM CELLS

Linking Transgene Expression of Engineered Mesenchymal Stem Cells and Angiopoietin-1–induced Differentiation to Target Cancer Angiogenesis

(2010) Claudius Conrad et al.   ANNALS OF SURGERY

Genetic Engineering of Mesenchymal Stem Cells and Its Application in Human Disease Therapy

(2010) Conrad P. Hodgkinson et al.   HUMAN GENE THERAPY

Mesenchymal stem cells enhance growth and metastasis of colon cancer

(2010) Kei Shinagawa et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting of XIAP Combined with Systemic Mesenchymal Stem Cell-Mediated Delivery of sTRAIL Ligand Inhibits Metastatic Growth of Pancreatic Carcinoma Cells

(2010) Andrea Mohr et al.   STEM CELLS

Advances in mesenchymal stem cell-mediated gene therapy for cancer

(2010) Roisin M Dwyer et al.   Stem Cell Research & Therapy

Stem cell homing and angiomyogenesis in transplanted hearts are enhanced by combined intramyocardial SDF-1α delivery and endogenous cytokine signaling

(2009) Tiemin Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Targeting Tumor Stroma Using Engineered Mesenchymal Stem Cells Reduces the Growth of Pancreatic Carcinoma

(2009) Christoph Zischek et al.   ANNALS OF SURGERY

Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma

(2009) M. Vogler et al.   CANCER RESEARCH

Mesenchymal Stem Cells: Flip Side of the Coin

(2009) Pravin J. Mishra et al.   CANCER RESEARCH

Mesenchymal Stem Cell Homing: The Devil Is in the Details

(2009) Jeffrey M. Karp et al.   Cell Stem Cell

Sca-1 + Stem Cell Survival and Engraftment in the Infarcted Heart

(2009) Gang Lu et al.   CIRCULATION

Growth inhibition of colorectal carcinoma by lentiviral TRAIL-transgenic human mesenchymal stem cells requires their substantial intratumoral presence

(2009) Jana Luetzkendorf et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Safety, Pharmacokinetics, and Antitumor Activity of AMG 386, a Selective Angiopoietin Inhibitor, in Adult Patients With Advanced Solid Tumors

(2009) Roy S. Herbst et al.   JOURNAL OF CLINICAL ONCOLOGY

Pharmacological Preconditioning of Mesenchymal Stem Cells with Trimetazidine (1-[2,3,4-Trimethoxybenzyl]piperazine) Protects Hypoxic Cells against Oxidative Stress and Enhances Recovery of Myocardial Function in Infarcted Heart through Bcl-2 Expression

(2009) S. Wisel et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy

(2009) L. S. Sasportas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Bone Marrow-Derived Mesenchymal Stromal Cells Expressing S-TRAIL as a Cellular Delivery Vehicle for Human Glioma Therapy

(2009) Lata G. Menon et al.   STEM CELLS

VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma

(2008) B M Beckermann et al.   BRITISH JOURNAL OF CANCER

Tumor-Targeted Interferon-α Delivery by Tie2-Expressing Monocytes Inhibits Tumor Growth and Metastasis

(2008) Michele De Palma et al.   CANCER CELL

Prodrug cancer gene therapy

(2008) Cestmir Altaner   CANCER LETTERS

The inflammatory chemokines CCL2 and CCL5 in breast cancer

(2008) Gali Soria et al.   CANCER LETTERS

Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells

(2008) P. J. Mishra et al.   CANCER RESEARCH

Targeting XIAP Bypasses Bcl-2-Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

(2008) M. Vogler et al.   CANCER RESEARCH

Regulation of Tumor-Stromal Fibroblast Interactions: Implications in Anticancer Therapy

(2008) Hippokratis Kiaris et al.   CURRENT MEDICINAL CHEMISTRY

Over-expression of CXCR4 on mesenchymal stem cells augments myoangiogenesis in the infarcted myocardium

(2008) Dongsheng Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pre-Treatment of Mesenchymal Stem Cells With a Combination of Growth Factors Enhances Gap Junction Formation, Cytoprotective Effect on Cardiomyocytes, and Therapeutic Efficacy for Myocardial Infarction

(2008) Joo-Yong Hahn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfare

(2008) Maarten F Corsten et al.   LANCET ONCOLOGY

Targeted Migration of Mesenchymal Stem Cells Modified With CXCR4 Gene to Infarcted Myocardium Improves Cardiac Performance

(2008) Zhaokang Cheng et al.   MOLECULAR THERAPY

Tumor Angiogenesis

(2008) Robert S. Kerbel   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxic Preconditioning Results in Increased Motility and Improved Therapeutic Potential of Human Mesenchymal Stem Cells

(2008) Ivana Rosová et al.   STEM CELLS