mTORC1 and mTORC2 Play Different Roles in the Functional Survival of Transplanted Adipose-Derived Stromal Cells in Hind Limb Ischemic Mice Via Regulating Inflammation In Vivo

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Adipose Stromal Cells Amplify Angiogenic Signaling via the VEGF/mTOR/Akt Pathway in a Murine Hindlimb Ischemia Model: A 3D Multimodality Imaging Study

(2012) Weiwei Fan et al.   PLoS One

X-Ray-Visible Microcapsules Containing Mesenchymal Stem Cells Improve Hind Limb Perfusion in a Rabbit Model of Peripheral Arterial Disease

(2012) Dorota A. Kedziorek et al.   STEM CELLS

Concise Review: Adipose-Derived Stem Cells as a Novel Tool for Future Regenerative Medicine

(2012) Hiroshi Mizuno et al.   STEM CELLS

Molecular Imaging of Bone Marrow Mononuclear Cell Survival and Homing in Murine Peripheral Artery Disease

(2012) Koen E.A. van der Bogt et al.   JACC-Cardiovascular Imaging

S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt

(2011) Ruomin Di et al.   BIOCHEMICAL JOURNAL

Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies

(2011) M. Gupta et al.   BLOOD

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

(2011) H Kato et al.   CELL DEATH AND DIFFERENTIATION

Novel MicroRNA Prosurvival Cocktail for Improving Engraftment and Function of Cardiac Progenitor Cell Transplantation

(2011) S. Hu et al.   CIRCULATION

2011 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Peripheral Artery Disease (Updating the 2005 Guideline)

(2011) Thom W. Rooke et al.   CIRCULATION

Mammalian Target of Rapamycin Complex 2 (mTORC2) Negatively Regulates Toll-like Receptor 4-mediated Inflammatory Response via FoxO1

(2011) Jonathan Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functionalized Scaffold-mediated Interleukin 10 Gene Delivery Significantly Improves Survival Rates of Stem Cells In Vivo

(2011) Carolyn Holladay et al.   MOLECULAR THERAPY

Heart regeneration

(2011) Michael A. Laflamme et al.   NATURE

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

(2011) Greg M Delgoffe et al.   NATURE IMMUNOLOGY

Mesenchymal stem cell–based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α

(2011) Yi Liu et al.   NATURE MEDICINE

Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer

(2011) Ole Audun Werner Haabeth et al.   Nature Communications

IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin

(2010) S. Botto et al.   BLOOD

Inflammation in Peripheral Artery Disease

(2010) Gregorio Brevetti et al.   CIRCULATION

mTORC1-S6K Activation by Endotoxin Contributes to Cytokine Up-Regulation and Early Lethality in Animals

(2010) Po-Shun Lee et al.   PLoS One

Adipose Tissue Derived Stem Cells Secretome: Soluble Factors and Their Roles in Regenerative Medicine

(2010) Antonio J. Braga Osorio Gomes Salgado et al.   Current Stem Cell Research & Therapy

Participation of Mammalian Target of Rapamycin Complex 1 in Toll-Like Receptor 2– and 4–Induced Neutrophil Activation and Acute Lung Injury

(2009) Emmanuel Lorne et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Role of TNFα in Early Chemokine Production and Leukocyte Infiltration into Heart Allografts

(2009) D. Ishii et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Noninvasive De novo Imaging of Human Embryonic Stem Cell-Derived Teratoma Formation

(2009) F. Cao et al.   CANCER RESEARCH

Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway

(2009) Narasimman Gurusamy et al.   CARDIOVASCULAR RESEARCH

Trafficking Mesenchymal Stem Cell Engraftment and Differentiation in Tumor-Bearing Mice by Bioluminescence Imaging

(2009) Hui Wang et al.   STEM CELLS

Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth

(2009) Hui Wang et al.   STEM CELLS

Systems approaches to preventing transplanted cell death in cardiac repair

(2008) Thomas E. Robey et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Emerging hurdles in stem cell therapy for peripheral vascular disease

(2008) Xabier L. Aranguren et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts

(2008) R.-J. Swijnenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IFATS Collection: Adipose-Derived Stromal Cells Improve the Foreign Body Response

(2008) Heather L. Prichard et al.   STEM CELLS

Myocardin A Enhances Telomerase Activities in Adipose Tissue Mesenchymal Cells and Embryonic Stem Cells Undergoing Cardiovascular Myogenic Differentiation

(2007) Rosalinda Madonna et al.   STEM CELLS