Concise Review: Dissecting a Discrepancy in the Literature: Do Mesenchymal Stem Cells Support or Suppress Tumor Growth?

Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)

(2010) F. T. Martin et al.   BREAST CANCER RESEARCH AND TREATMENT

The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivo

(2010) Yan-rong Lu et al.   CANCER BIOLOGY & THERAPY

Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter

(2010) A. Torsvik et al.   CANCER RESEARCH

Reciprocal Activation of Prostate Cancer Cells and Cancer-Associated Fibroblasts Stimulates Epithelial-Mesenchymal Transition and Cancer Stemness

(2010) E. Giannoni et al.   CANCER RESEARCH

Mesenchymal stromal cells alone or expressing interferon-β suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment

(2010) Shannon Kidd et al.   CYTOTHERAPY

Mesenchymal stem cell-conditioned medium accelerates skin wound healing: An in vitro study of fibroblast and keratinocyte scratch assays

(2010) M.N.M. Walter et al.   EXPERIMENTAL CELL RESEARCH

Pitfalls in spontaneous in vitro transformation of human mesenchymal stem cells

(2010) S. Garcia et al.   EXPERIMENTAL CELL RESEARCH

Mesenchymal stem cells enhance growth and metastasis of colon cancer

(2010) Kei Shinagawa et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor cell behaviour modulation by mesenchymal stromal cells

(2010) Lucia Kucerova et al.   Molecular Cancer

Isolation and Perivascular Localization of Mesenchymal Stem Cells From Mouse Brain

(2010) Seok-Gu Kang et al.   NEUROSURGERY

A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype

(2010) Ruth S. Waterman et al.   PLoS One

Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway

(2010) Venkata Ramesh Dasari et al.   PLoS One

Human Bone Marrow Mesenchymal Stem Cells Display Anti-Cancer Activity in SCID Mice Bearing Disseminated Non-Hodgkin's Lymphoma Xenografts

(2010) Paola Secchiero et al.   PLoS One

Cord Blood Stem Cell-Mediated Induction of Apoptosis in Glioma Downregulates X-Linked Inhibitor of Apoptosis Protein (XIAP)

(2010) Venkata Ramesh Dasari et al.   PLoS One

Mesenchymal Stem Cells Promote Mammosphere Formation and Decrease E-Cadherin in Normal and Malignant Breast Cells

(2010) Ann H. Klopp et al.   PLoS One

Effects of transplantation of adipose tissue-derived stem cells on prostate tumor

(2010) Guiting Lin et al.   PROSTATE

Adipose tissue-derived stem cells promote prostate tumor growth

(2010) Lukas Prantl et al.   PROSTATE

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

(2010) Ruenn Chai Lai et al.   Stem Cell Research

Advances in mesenchymal stem cell-mediated gene therapy for cancer

(2010) Roisin M Dwyer et al.   Stem Cell Research & Therapy

Mesenchymal stem cells produce Wnt isoforms and TGF-β1 that mediate proliferation and procollagen expression by lung fibroblasts

(2009) Keith D. Salazar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Matrix elasticity regulates the secretory profile of human bone marrow-derived multipotent mesenchymal stromal cells (MSCs)

(2009) F. Philipp Seib et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long-term Cultures of Bone Marrow–Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation

(2009) Gro Vatne Røsland et al.   CANCER RESEARCH

Human Bone Marrow-Derived Mesenchymal Stem Cells for Intravascular Delivery of Oncolytic Adenovirus  24-RGD to Human Gliomas

(2009) R. L. Yong et al.   CANCER RESEARCH

White Adipose Tissue Cells Are Recruited by Experimental Tumors and Promote Cancer Progression in Mouse Models

(2009) Y. Zhang et al.   CANCER RESEARCH

Epithelial-mesenchymal transition in cancer development and its clinical significance

(2009) Masaaki Iwatsuki et al.   CANCER SCIENCE

Tissue-resident stem cells promote breast cancer growth and metastasis

(2009) Fabian L. Muehlberg et al.   CARCINOGENESIS

Isolation and characterization of stem cells from the human parathyroid gland

(2009) Y-R. V. Shih et al.   CELL PROLIFERATION

Mesenchymal Stem Cell Carriers Protect Oncolytic Measles Viruses from Antibody Neutralization in an Orthotopic Ovarian Cancer Therapy Model

(2009) E. K. Mader et al.   CLINICAL CANCER RESEARCH

Cancer-associated fibroblasts and tumor growth – bystanders turning into key players

(2009) Arne Östman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Pharmaceutical and Cellular Strategies in Prophylaxis and Treatment of Graft-Versus-Host Disease

(2009) D. Wolff et al.   CURRENT PHARMACEUTICAL DESIGN

Human bone marrow mesenchymal cells express NG2: possible increase in discriminative ability of flow cytometry during mesenchymal stromal cell identification

(2009) Ilknur Kozanoglu et al.   CYTOTHERAPY

Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1

(2009) Y Zhu et al.   LEUKEMIA

Adipose-derived Stem Cells as Therapeutic Delivery Vehicles of an Oncolytic Virus for Glioblastoma

(2009) Darnell T Josiah et al.   MOLECULAR THERAPY

Platelet-Derived Growth Factor BB Mediates the Tropism of Human Mesenchymal Stem Cells for Malignant Gliomas

(2009) Nobuhiro Hata et al.   NEUROSURGERY

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs

(2009) Tian Sheng Chen et al.   NUCLEIC ACIDS RESEARCH

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

(2009) Erika L. Spaeth et al.   PLoS One

Adult Stromal Cells Derived from Human Adipose Tissue Provoke Pancreatic Cancer Cell Death both In Vitro and In Vivo

(2009) Beatrice Cousin et al.   PLoS One

Direct Evidence of Mesenchymal Stem Cell Tropism for Tumor and Wounding Microenvironments Using In Vivo Bioluminescent Imaging

(2009) Shannon Kidd et al.   STEM CELLS

Fetal mesenchymal stem cells: isolation, properties and potential use in perinatology and regenerative medicine

(2008) L Gucciardo et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells

(2008) K. Otsu et al.   BLOOD

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

(2008) Z. Zeng et al.   BLOOD

VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma

(2008) B M Beckermann et al.   BRITISH JOURNAL OF CANCER

Hyperthermia-treated mesenchymal stem cells exert antitumor effects on human carcinoma cell line

(2008) Jung Ah Cho et al.   CANCER

Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling

(2008) Ling Qiao et al.   CANCER LETTERS

Gene Therapy Using TRAIL-Secreting Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells against Intracranial Glioma

(2008) S. M. Kim et al.   CANCER RESEARCH

Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells

(2008) P. J. Mishra et al.   CANCER RESEARCH

A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1

(2008) Huiming Sheng et al.   CELL RESEARCH

Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model

(2008) Ling Qiao et al.   CELL RESEARCH

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

Bone marrow-derived cells and tumor growth: Contribution of bone marrow-derived cells to tumor micro-environments with special focus on mesenchymal stem cells

(2008) Berber D. Roorda et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells

(2008) E Spaeth et al.   GENE THERAPY

Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells

(2008) Alan P. Molloy et al.   INTERNATIONAL JOURNAL OF CANCER

The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study

(2008) H Ning et al.   LEUKEMIA

CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells

(2008) L. Jin et al.   MOLECULAR CANCER THERAPEUTICS

Mesenchymal Stem Cells in Early Entry of Breast Cancer into Bone Marrow

(2008) Kelly E. Corcoran et al.   PLoS One

Mesenchymal Stem Cells Derived from Human Adipose Tissues Favor Tumor Cell Growth in vivo

(2008) Ji Min Yu et al.   STEM CELLS AND DEVELOPMENT

A Population of Multipotent CD34-Positive Adipose Stromal Cells Share Pericyte and Mesenchymal Surface Markers, Reside in a Periendothelial Location, and Stabilize Endothelial Networks

(2007) Dmitry O. Traktuev et al.   CIRCULATION RESEARCH

Selected Stro-1-enriched bone marrow stromal cells display a major suppressive effect on lymphocyte proliferation

(2007) A. NASEF et al.   International Journal of Laboratory Hematology