Phosphatase and Tensin Homolog Regulates the Pluripotent State and Lineage Fate Choice in Human Embryonic Stem Cells

Controlling embryonic stem cell proliferation and pluripotency: the role of PI3K- and GSK-3-dependent signalling

(2011) Melanie J. Welham et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Control of the Embryonic Stem Cell State

(2011) Richard A. Young   CELL

Loss of Pten Causes Tumor Initiation Following Differentiation of Murine Pluripotent Stem Cells Due to Failed Repression of Nanog

(2011) Anne G. Lindgren et al.   PLoS One

The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells

(2010) Jung Sun Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Different Flavors of Pluripotency, Molecular Mechanisms, and Practical Implications

(2010) Christa Buecker et al.   Cell Stem Cell

Pax6 Is a Human Neuroectoderm Cell Fate Determinant

(2010) Xiaoqing Zhang et al.   Cell Stem Cell

mTOR-Mediated Activation of p70 S6K Induces Differentiation of Pluripotent Human Embryonic Stem Cells

(2010) Charles A. Easley et al.   Cellular Reprogramming

FGF-2 modulates Wnt signaling in undifferentiated hESC and iPS cells through activated PI3-K/GSK3β signaling

(2010) Vanessa M.Y. Ding et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dysregulated Gene Expression During Hematopoietic Differentiation From Human Embryonic Stem Cells

(2010) Gautam Dravid et al.   MOLECULAR THERAPY

Extrinsic regulation of pluripotent stem cells

(2010) Martin F. Pera et al.   NATURE

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

(2010) J. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells

(2010) Chul-Ho Jeong et al.   STEM CELLS

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Inhibition of Caspase-mediated Anoikis Is Critical for Basic Fibroblast Growth Factor-sustained Culture of Human Pluripotent Stem Cells

(2009) Xiaofang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Continuum of Cell States Spans Pluripotency and Lineage Commitment in Human Embryonic Stem Cells

(2009) Shelley R. Hough et al.   PLoS One

mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells

(2009) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Mammary Stem/Progenitor Cells by PTEN/Akt/β-Catenin Signaling

(2009) Hasan Korkaya et al.   PLOS BIOLOGY

Localized decrease of β-catenin contributes to the differentiation of human embryonic stem cells

(2008) Hayley Lam et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tenets of PTEN Tumor Suppression

(2008) Leonardo Salmena et al.   CELL

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

(2008) Xi Chen et al.   CELL

A Hierarchical Network Controls Protein Translation during Murine Embryonic Stem Cell Self-Renewal and Differentiation

(2008) Prabha Sampath et al.   Cell Stem Cell

Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/ -catenin, Activin/Nodal and BMP signaling

(2008) T. Sumi et al.   DEVELOPMENT

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

T-Cell Factor 3 Regulates Embryonic Stem Cell Pluripotency and Self-Renewal by the Transcriptional Control of Multiple Lineage Pathways

(2008) Wai-Leong Tam et al.   STEM CELLS

A Self-Renewal Program Controls the Expansion of Genetically Unstable Cancer Stem Cells in Pluripotent Stem Cell-Derived Tumors

(2008) Anne E. Conway et al.   STEM CELLS

Integrated Chemical Genomics Reveals Modifiers of Survival in Human Embryonic Stem Cells

(2008) Robert Damoiseaux et al.   STEM CELLS