Interferon-Gamma Modification of Mesenchymal Stem Cells: Implications of Autologous and Allogeneic Mesenchymal Stem Cell Therapy in Allotransplantation
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Interferon-Gamma Modification of Mesenchymal Stem Cells: Implications of Autologous and Allogeneic Mesenchymal Stem Cell Therapy in Allotransplantation
Authors
Keywords
Mesenchymal stem cells, Autologous, Allogeneic, Interferon-gamma, Preactivation, Modification, T cells, Immunosuppression, Immunogenicity, Allotransplantation, Allograft rejection, Cellular therapy, Monotherapy, Immunosuppressive drugs, Regeneration, Clinical trials
Journal
Stem Cell Reviews and Reports
Volume 10, Issue 3, Pages 351-375
Publisher
Springer Nature
Online
2014-02-08
DOI
10.1007/s12015-014-9495-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Exosomes As a Short-Range Mechanism to Spread Alloantigen between Dendritic Cells during T Cell Allorecognition
- (2014) A. Montecalvo et al. JOURNAL OF IMMUNOLOGY
- Pretransplant Infusion of Mesenchymal Stem Cells Prolongs the Survival of a Semiallogeneic Heart Transplant through the Generation of Regulatory T Cells
- (2014) F. Casiraghi et al. JOURNAL OF IMMUNOLOGY
- Prostaglandin E2 Potentiates Mesenchymal Stem Cell-Induced IL-10+IFN- +CD4+ Regulatory T Cells To Control Transplant Arteriosclerosis
- (2013) W.-T. Hsu et al. JOURNAL OF IMMUNOLOGY
- Mesenchymal Stem Cells Tune the Development of Monocyte-Derived Dendritic Cells Toward a Myeloid-Derived Suppressive Phenotype through Growth-Regulated Oncogene Chemokines
- (2013) H.-W. Chen et al. JOURNAL OF IMMUNOLOGY
- Third-party Mesenchymal Stem Cells Improved Human Islet Transplantation in a Humanized Diabetic Mouse Model
- (2013) Hao Wu et al. MOLECULAR THERAPY
- Novel Mechanism of Inhibition of Dendritic Cells Maturation by Mesenchymal Stem Cells via Interleukin-10 and the JAK1/STAT3 Signaling Pathway
- (2013) Wen-hua Liu et al. PLoS One
- Role of Injured Pancreatic Extract Promotes Bone Marrow-Derived Mesenchymal Stem Cells Efficiently Differentiate into Insulin-Producing Cells
- (2013) Hongbin Xie et al. PLoS One
- EphB and Ephrin-B Interactions Mediate Human Mesenchymal Stem Cell Suppression of Activated T-Cells
- (2013) Thao M. Nguyen et al. STEM CELLS AND DEVELOPMENT
- Decidual Stromal Cells Promote Regulatory T Cells and Suppress Alloreactivity in a Cell Contact-Dependent Manner
- (2013) Tom Erkers et al. STEM CELLS AND DEVELOPMENT
- Mesenchymal stromal cells and kidney transplantation: pretransplant infusion protects from graft dysfunction while fostering immunoregulation
- (2013) Norberto Perico et al. TRANSPLANT INTERNATIONAL
- Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells
- (2013) Patricia Luz-Crawford et al. Stem Cell Research & Therapy
- Autologous Bone Marrow-Derived Mesenchymal Stromal Cells for the Treatment of Allograft Rejection After Renal Transplantation: Results of a Phase I Study
- (2013) Marlies E.J. Reinders et al. Stem Cells Translational Medicine
- Mesenchymal-Stem-Cell-Induced Immunoregulation Involves FAS-Ligand-/FAS-Mediated T Cell Apoptosis
- (2012) Kentaro Akiyama et al. Cell Stem Cell
- Human mesenchymal stem cells suppress donor CD4+T cell proliferation and reduce pathology in a humanized mouse model of acute graft-versus-host disease
- (2012) L. M. Tobin et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The influence of cardiovascular risk factors on bone marrow mesenchymal stromal cell fitness
- (2012) Klaus Neef et al. CYTOTHERAPY
- Mesenchymal stem cell-conditioned medium accelerates regeneration of human renal proximal tubule epithelial cells after gentamicin toxicity
- (2012) Reza Moghadasali et al. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
- Immunomodulatory effects of mesenchymal stem cells in a rat corneal allograft rejection model
- (2012) Zhe Jia et al. EXPERIMENTAL EYE RESEARCH
- Anti-donor immune responses elicited by allogeneic mesenchymal stem cells: what have we learned so far?
- (2012) Matthew D Griffin et al. IMMUNOLOGY AND CELL BIOLOGY
- Characterization and functionality of the CD200–CD200R system during mesenchymal stromal cell interactions with T-lymphocytes
- (2012) Mehdi Najar et al. IMMUNOLOGY LETTERS
- IFN-γ-primed human bone marrow mesenchymal stem cells induce tumor cell apoptosis in vitro via tumor necrosis factor-related apoptosis-inducing ligand
- (2012) Jingchun Du et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Induction Therapy With Autologous Mesenchymal Stem Cells in Living-Related Kidney Transplants
- (2012) Jianming Tan et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Activated mesenchymal stem cells increase wound tensile strength in aged mouse model via macrophages
- (2012) Simon Lee et al. JOURNAL OF SURGICAL RESEARCH
- Mesenchymal Stem Cells Provide an Advantageous Tumor Microenvironment for the Restoration of Cancer Stem Cells
- (2012) Kanako Nishimura et al. PATHOBIOLOGY
- Mesenchymal Stem Cells Repress Th17 Molecular Program through the PD-1 Pathway
- (2012) Patricia Luz-Crawford et al. PLoS One
- Donor-Derived Mesenchymal Stem Cells Combined With Low-Dose Tacrolimus Prevent Acute Rejection After Renal Transplantation
- (2012) Yanwen Peng et al. TRANSPLANTATION
- Detrimental effects of rat mesenchymal stromal cell pre-treatment in a model of acute kidney rejection
- (2012) Martina Seifert et al. Frontiers in Immunology
- Application of MultiStem® Allogeneic Cells for Immunomodulatory Therapy: Clinical Progress and Pre-Clinical Challenges in Prophylaxis for Graft Versus Host Disease
- (2012) Bart Vaes et al. Frontiers in Immunology
- The impact of inflammatory licensing on heme oxygenase-1-mediated induction of regulatory T cells by human mesenchymal stem cells
- (2011) D. Mougiakakos et al. BLOOD
- The source of human mesenchymal stromal cells influences their TLR profile as well as their functional properties
- (2011) Gordana Raicevic et al. CELLULAR IMMUNOLOGY
- Mesenchymal stromal cells impair the differentiation of CD14++ CD16− CD64+ classical monocytes into CD14++ CD16+ CD64++ activate monocytes
- (2011) Bárbara Du Rocher et al. CYTOTHERAPY
- Immunomodulatory Function of Regulatory Dendritic Cells Induced by Mesenchymal Stem Cells
- (2011) Zhi-Gang Zhao et al. IMMUNOLOGICAL INVESTIGATIONS
- Immunogenicity of allogeneic mesenchymal stem cells
- (2011) Sabine Schu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation
- (2011) Moïra François et al. MOLECULAR THERAPY
- Mesenchymal stem cells in kidney inflammation and repair
- (2011) ANDREA F. WISE et al. NEPHROLOGY
- Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells
- (2011) S. Chiesa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pretreatment with Interferon-γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis
- (2011) Marjolijn Duijvestein et al. STEM CELLS
- Human Mesenchymal Stem Cells from Adipose Tissue and Amnion Influence T-Cells Depending on Stimulation Method and Presence of Other Immune Cells
- (2011) Barbara Kronsteiner et al. STEM CELLS AND DEVELOPMENT
- Graft-infiltrating cells expressing a CD200 transgene prolong allogeneic skin graft survival in association with local increases in Foxp3+Treg and mast cells
- (2011) Reginald M. Gorczynski et al. TRANSPLANT IMMUNOLOGY
- Features of synergism between mesenchymal stem cells and immunosuppressive drugs in a murine heart transplantation model
- (2011) Elke Eggenhofer et al. TRANSPLANT IMMUNOLOGY
- Myeloid-Derived Suppressor Cells Protect Islet Transplants by B7-H1 Mediated Enhancement of T Regulatory Cells
- (2011) Hong-Shiue Chou et al. TRANSPLANTATION
- Mechanisms of Rejection: Current Perspectives
- (2011) Kathryn J. Wood et al. TRANSPLANTATION
- Safety and Immunological Effects of Mesenchymal Stem Cell Transplantation in Patients With Multiple Sclerosis and Amyotrophic Lateral Sclerosis
- (2010) Dimitrios Karussis et al. ARCHIVES OF NEUROLOGY
- Mesenchymal stem cells express serine protease inhibitor to evade the host immune response
- (2010) N. El Haddad et al. BLOOD
- Autologous Mesenchymal Stromal Cells and Kidney Transplantation: A Pilot Study of Safety and Clinical Feasibility
- (2010) N. Perico et al. Clinical Journal of the American Society of Nephrology
- Fetal and adult multipotent mesenchymal stromal cells are killed by different pathways
- (2010) Cecilia Götherström et al. CYTOTHERAPY
- Mesenchymal Stem Cells Enhance Allogeneic Islet Engraftment in Nonhuman Primates
- (2010) D. M. Berman et al. DIABETES
- Mesenchymal Stem Cells Prevent Acute Rejection and Prolong Graft Function in Pancreatic Islet Transplantation
- (2010) Biancamaria Longoni et al. Diabetes Technology & Therapeutics
- More insight into mesenchymal stem cells and their effects inside the body
- (2010) Zhongmin Zou et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Immunological Aspects of Allogeneic Mesenchymal Stem Cell Therapies
- (2010) Matthew D. Griffin et al. HUMAN GENE THERAPY
- Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins
- (2010) Sioud INTERNATIONAL JOURNAL OF ONCOLOGY
- Mesenchymal Stem Cells Protect Breast Cancer Cells through Regulatory T Cells: Role of Mesenchymal Stem Cell-Derived TGF-
- (2010) S. A. Patel et al. JOURNAL OF IMMUNOLOGY
- Inhibition of Immune Synapse by Altered Dendritic Cell Actin Distribution: A New Pathway of Mesenchymal Stem Cell Immune Regulation
- (2010) A. Aldinucci et al. JOURNAL OF IMMUNOLOGY
- Pro-Inflammatory Cytokines, IFNγ and TNFα, Influence Immune Properties of Human Bone Marrow and Wharton Jelly Mesenchymal Stem Cells Differentially
- (2010) S. Jyothi Prasanna et al. PLoS One
- Murine Bone Marrow Mesenchymal Stem Cells Cause Mature Dendritic Cells to Promote T-Cell Tolerance
- (2010) Q. Wang et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Evidence for the Involvement of Galectin-3 in Mesenchymal Stem Cell Suppression of Allogeneic T-Cell Proliferation
- (2010) M. Sioud et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- New Insights into Mesenchymal Stromal Cell-Mediated T-Cell Suppression Through Galectins
- (2010) M. Sioud SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Human Foreskin Fibroblasts Exert Immunomodulatory Properties by a Different Mechanism to Bone Marrow Stromal/Stem Cells
- (2010) Naohisa Wada et al. STEM CELLS AND DEVELOPMENT
- Mesenchymal Stem Cells Negatively Regulate Dendritic Lineage Commitment of Umbilical-Cord-Blood-Derived Hematopoietic Stem Cells: An Unappreciated Mechanism as Immunomodulators
- (2010) Hsiu-Yu Lai et al. TISSUE ENGINEERING PART A
- The immunosuppressive effect of embryonic stem cells and mesenchymal stem cells on both primary and secondary alloimmune responses
- (2010) Kyu Hyun Han et al. TRANSPLANT IMMUNOLOGY
- Mesenchymal stem cells together with mycophenolate mofetil inhibit antigen presenting cell and T cell infiltration into allogeneic heart grafts
- (2010) E. Eggenhofer et al. TRANSPLANT IMMUNOLOGY
- Regulatory T-Cell Generation and Kidney Allograft Tolerance Induced by Mesenchymal Stem Cells Associated With Indoleamine 2,3-Dioxygenase Expression
- (2010) Wei Ge et al. TRANSPLANTATION
- Humoral Autoimmunity and Transplant Vasculopathy: When Allo is Not Enough
- (2010) Thet Su Win et al. TRANSPLANTATION
- Mesenchymal stem cell therapy: Two steps forward, one step back
- (2010) James Ankrum et al. TRENDS IN MOLECULAR MEDICINE
- Infusion of Mesenchymal Stem Cells and Rapamycin Synergize to Attenuate Alloimmune Responses and Promote Cardiac Allograft Tolerance
- (2009) W. Ge et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Adult Human Mesenchymal Stem Cells Added to Corticosteroid Therapy for the Treatment of Acute Graft-versus-Host Disease
- (2009) Partow Kebriaei et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2
- (2009) G. M. Spaggiari et al. BLOOD
- Long-term Cultures of Bone Marrow–Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation
- (2009) Gro Vatne Røsland et al. CANCER RESEARCH
- Cell contact, prostaglandin E2and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+regulatory T cells
- (2009) K. English et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Pathways of major histocompatibility complex allorecognition
- (2009) Behdad Afzali et al. Current Opinion in Organ Transplantation
- Mesenchymal stem cells are functionally abnormal in patients with immune thrombocytopenic purpura
- (2009) Jose Antonio Pérez-Simón et al. CYTOTHERAPY
- Mesenchymal Stem Cells Prevent the Rejection of Fully Allogenic Islet Grafts by the Immunosuppressive Activity of Matrix Metalloproteinase-2 and -9
- (2009) Y. Ding et al. DIABETES
- Costimulatory pathways in transplantation: challenges and new developments
- (2009) Xian C. Li et al. IMMUNOLOGICAL REVIEWS
- Marginal mass islet transplantation with autologous mesenchymal stem cells promotes long-term islet allograft survival and sustained normoglycemia
- (2009) Mario G. Solari et al. JOURNAL OF AUTOIMMUNITY
- Immunomodulatory properties of human periodontal ligament stem cells
- (2009) Naohisa Wada et al. JOURNAL OF CELLULAR PHYSIOLOGY
- PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
- (2009) Loise M. Francisco et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Expression of a CD200 Transgene Is Necessary for Induction but Not Maintenance of Tolerance to Cardiac and Skin Allografts
- (2009) R. M. Gorczynski et al. JOURNAL OF IMMUNOLOGY
- Allogeneic Mesenchymal Stem Cells for Treatment of Experimental Autoimmune Encephalomyelitis
- (2009) Moutih Rafei et al. MOLECULAR THERAPY
- Direct Imaging of Immune Rejection and Memory Induction by Allogeneic Mesenchymal Stromal Cells
- (2009) Lior Zangi et al. STEM CELLS
- Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R
- (2009) Christiane A. Opitz et al. STEM CELLS
- Galectin-1 and Semaphorin-3A Are Two Soluble Factors Conferring T-Cell Immunosuppression to Bone Marrow Mesenchymal Stem Cell
- (2009) Yves Lepelletier et al. STEM CELLS AND DEVELOPMENT
- The Negative Co-Signaling Molecule B7-H4 Is Expressed by Human Bone Marrow–Derived Mesenchymal Stem Cells and Mediates its T-Cell Modulatory Activity
- (2009) Qun Xue et al. STEM CELLS AND DEVELOPMENT
- The B-Cell Response to Protein Antigens in Immunity and Transplantation
- (2009) David M. Tarlinton et al. TRANSPLANTATION
- Use of donor bone marrow mesenchymal stem cells for treatment of skin allograft rejection in a preclinical rat model
- (2008) Paolo Sbano et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population
- (2008) B. Zhang et al. BLOOD
- A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1
- (2008) Huiming Sheng et al. CELL RESEARCH
- Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide
- (2008) Guangwen Ren et al. Cell Stem Cell
- IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
- (2008) David Polchert et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation
- (2008) Tatyana B. Prigozhina et al. EXPERIMENTAL HEMATOLOGY
- MHC expression kinetics and immunogenicity of mesenchymal stromal cells after short-term IFN-γ challenge
- (2008) Wing Keung Chan et al. EXPERIMENTAL HEMATOLOGY
- Mesenchymal Stromal Cells Engineered to Express Erythropoietin Induce Anti-erythropoietin Antibodies and Anemia in Allorecipients
- (2008) Philippe M Campeau et al. MOLECULAR THERAPY
- Therapeutic Potential of Adult Bone Marrow Stem Cells in Liver Disease and Delivery Approaches
- (2008) You Qing Xu et al. Stem Cell Reviews and Reports
- Mesenchymal Stem Cells Alter Migratory Property of T and Dendritic Cells to Delay the Development of Murine Lethal Acute Graft-Versus-Host Disease
- (2008) Hong Li et al. STEM CELLS
- Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate
- (2008) F.C. Popp et al. TRANSPLANT IMMUNOLOGY
- Role of mesenchymal stromal cells in solid organ transplantation
- (2008) Peiman Hematti Transplantation Reviews
- Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation
- (2007) Karen English et al. IMMUNOLOGY LETTERS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now