Article
Clinical Neurology
Zhuanghui Wang, Yuluo Rong, Pengyu Tang, Wu Ye, Chengyue Ji, Jiaxing Wang, Xuhui Ge, Wei Liu, Qingqing Li, Weihua Cai
Summary: The study revealed that 61.4% of lumbar spinal stenosis (LSS) patients also have asymptomatic spondylotic cervical spinal stenosis (ASCSS), with lumbar lordosis angle (LLA) >35.85 degrees and dural sac cross-sectional area (DCSA) <84.50 mm^2 being risk factors for ASCSS development. Additionally, the cervical stenosis index showed a significant positive correlation with the lumbar stenosis index.
WORLD NEUROSURGERY
(2021)
Article
Medicine, Research & Experimental
Youhyun Song, Ja-Eun Choi, Yu-Jin Kwon, Hyuk-Jae Chang, Jung Oh Kim, Da-Hyun Park, Jae-Min Park, Seong-Jin Kim, Ji Won Lee, Kyung-Won Hong
Summary: This study identified 6 susceptibility loci and positional candidate genes for CVDs in HTN, DM, and DL patients using an unprecedented study design. One locus (17q25.3) was commonly associated with CAD. These associations warrant validation in additional studies for potential therapeutic applications.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Shinjeong Song, Hye Ah Lee, Yeji Kim, Bo Kyung Jeon, Chang Mo Moon, Junbeom Park
Summary: This study aimed to examine the association between dynamic smoking habit change and cardiovascular risk in a population newly diagnosed with hypertension, diabetes, and dyslipidemia. The results showed that worsening of smoking habits was associated with an increased risk of cardiovascular events and death.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Wenjing Yang, Qiong Huang, Ling Han, Bing Wang, Nikhil Yawalkar, Zhenghua Zhang, Kexiang Yan
Summary: This study found that the genotypes rs12025144 and rs2066398 in the B7-H4 gene were associated with a higher prevalence of diabetes mellitus and dyslipidemia in psoriatic patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Marcus Kin Long Lai, Prudence Wing Hang Cheung, Dino Samartzis, Jason Pui Yin Cheung
Summary: This study defined multilevel lumbar developmental spinal stenosis (DSS) using a composite score model and determined its prevalence. By measuring the vertebral canal diameter, the study found that multiple levels of stenosis may lead to the risk of spinal canal compression.
GLOBAL SPINE JOURNAL
(2022)
Article
Multidisciplinary Sciences
Rasoul Kowsar, Alireza Mansouri
Summary: This study used a multi-level approach to establish the relationship between diabetes, blood biochemical markers, age, and BMI. The findings identified BMI and HbA1c as the best predictors of T2D.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Paul-Mihai Boarescu, Ioana Boarescu, Raluca Maria Pop, Stefan Horia Rosian, Ioana Corina Bocsan, Vasile Rus, Razvan Olimpiu Mada, Iulia Diana Popa, Nicholas Neagu, Adriana Elena Bulboaca, Anca Dana Buzoianu, Sorana D. Bolboaca
Summary: This study aimed to compare the oxidative stress biomarkers, pro-inflammatory cytokines, and histological changes induced by three cardiovascular risk factors. The results showed that hypertension, dyslipidemia, and type 1 diabetes mellitus all increased oxidative stress and inflammation, with type 1 diabetes mellitus having the most significant irreversible changes on the arterial wall.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Cardiac & Cardiovascular Systems
Wenke Cheng, Jingqi Zhuang, Siwei Chen
Summary: This study investigated the relationship between atherosclerotic indices and the prevalence of hypertension in Chinese adults without type 2 diabetes mellitus. The results showed that atherosclerotic indices were higher in the hypertensive population compared to the normotensive population, and systolic and diastolic blood pressure were positively correlated with these indices. The cholesterol index and non-HDL-C were identified as independent risk factors for hypertension prevalence.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Psychiatry
Eva Kathrin Lamade, Nicole Oezer, Bernhard Schaupp, Bertram Krumm, Michael Deuschle, Sibylle Haefner
Summary: This study aimed to investigate the association between cardiovascular risk factors identified during an index inpatient stay for schizophrenia and the subsequent ten-year duration and number of inpatient treatments. The results showed that hypertension was associated with longer duration of inpatient treatments and higher number of admissions, while type 2 diabetes mellitus and dyslipidemia were associated with a higher number of inpatient treatments. Screening for hypertension should be considered in all patients with schizophrenia.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Pediatrics
Meghana Selvaraj, Hemchand Krishna Prasad, Sherline White, Bala Prasanna, Thangavelu Sangaralingam
Summary: This study investigated the prevalence and determinants of dyslipidemia in children and adolescents with type 1 diabetes mellitus. The study found that glycosylated hemoglobin (HbA1C) was the most significant factor in determining the occurrence of dyslipidemia, and the prevalence of dyslipidemia in the study population was 67.3%.
INDIAN JOURNAL OF PEDIATRICS
(2023)
Review
Clinical Neurology
Farzin Farahbakhsh, Sepehr Khosravi, Vali Baigi, Masoud Pourghahramani Koltapeh, Amirmahdi Khayyamfar, Zahra Eskandari, Zahra Ghodsi, James Harrop, Vafa Rahimi-Movaghar
Summary: This study aimed to determine the prevalence of asymptomatic cervical spinal cord compression (CSCC) in patients with lumbar spinal stenosis (LSS) through systematic review and meta-analysis. The findings revealed a relatively high prevalence of asymptomatic CSCC in LSS patients. Therefore, spine surgeons are strongly recommended to exercise caution during surgery for lumbar stenosis and closely monitor individuals with symptomatic LSS for potential signs of emerging myelopathy.
GLOBAL SPINE JOURNAL
(2023)
Article
Anesthesiology
Ahmed J. Awad, Braden Jex, Gwynne Kirchen, Stacy Peterson, Sarah A. Endrizzi, Peter A. Pahapill
Summary: The study demonstrates the favorable long-term efficacy of SCS in treating neurogenic claudication, especially for patients without prior surgical decompression. Despite its retrospective nature and single-center design, the results suggest that SCS can be considered as part of conservative treatment to help patients alleviate spine-related pain.
Article
Orthopedics
Gen Xia, Xueru Li, Yanbing Shang, Bin Fu, Feng Jiang, Huan Liu, Yongdong Qiao
Summary: The study found that in patients with DLSS, the atrophy of muscles in stenotic segments of the spinal canal is significantly greater than in non-stenotic segments, and there is a strong positive correlation between the severity of multifidus atrophy and the severity of spinal stenosis.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Medicine, General & Internal
Thekraiat M. Al Quran, Ziad A. Bataineh, Abdel-Hameed Al-Mistarehi, Anas M. Zein Alaabdin, Hadeel Allan, Anood Al Qura'an, Shatha M. Weshah, Anfal A. Alanazi, Yousef S. Khader
Summary: This study investigated the prevalence and patterns of dyslipidemia among patients with T2DM in Jordan. It found that dyslipidemia is highly prevalent among these patients, with low HDL-C, high LDL-C, and hypertriglyceridemia being the most common patterns. Factors such as female gender, obesity, hypertension, longer T2DM duration, and poor glycemic control were associated with specific dyslipidemia patterns.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2022)
Article
Anesthesiology
Sung Hyun Lee, Sung-Ha Hwang, Young-Kwan Moon, Hyun Min Bae, Dong Eon Moon
Summary: This retrospective study evaluated the clinical outcomes and safety of TFFP in 112 patients, showing that TFFP using the Foramoon device was effective in improving pain scores, ODI, and walking distance without serious adverse events.