4.5 Article

Multifocal Osteolytic Lesions Within Lumbar Spine in a Middle-Aged Chinese Woman A Benign Metastasizing Leiomyoma?

Journal

SPINE
Volume 37, Issue 4, Pages E259-E263

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/BRS.0b013e31822e9578

Keywords

benign metastasizing leiomyoma; smooth muscle tumor of uncertain malignant potential; STUMP; spine

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Study Design. Case report. Objective. To describe a case presented as osteolytic lesions involving 2 inconsecutive lumbar, which was pathologically proved to be of smooth muscular origin. Summary of Background Data. Smooth muscle tumor of uncertain malignant potential (STUMP) could be diagnosed when the neoplasm showed some malignant behavior, whereas its histologic image revealed very low malignance. A 47-year-old woman presented with low back pain and numbness of the left lower extremity attributable to osteolytic lesions in the second and fourth lumbar vertebral bodies, which was subsequently diagnosed as STUMP. A benign metastasizing leiomyoma was highly suspected. Methods. Clinical, pathologic, and radiologic characters of the patient with STUMP confined within the lumbar spine were retrospectively reviewed. A mini review was also conducted. Results. We describe the first spine-confined case of STUMP. Conclusion. Significant new information in the growing literature of this rare and newly identified diagnosis has addressed the need for orthopedists to consider the STUMP diagnosis.

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