Review
Medicine, General & Internal
Youngmin Oh, Jongpil Eun
Summary: PEMLDF is a rare condition that can easily be misdiagnosed, but early diagnosis and treatment are crucial for optimal postoperative outcomes. Paying attention to the similarity of signal intensity of the mass and intervertebral disc on MRI scans, as well as looking for peripheral rim enhancement, are key factors in correctly diagnosing PEMLDF.
Article
Medicine, General & Internal
Oded Hershkovich, Yaakov Mor, Raphael Lotan
Summary: This retrospective study evaluated the effectiveness and tolerance of systemic steroid use in patients with acute lumbar radicular pain (ALRP). The results showed that IV steroid treatment was effective in relieving pain and allowing discharge in 70% of patients with a low complication rate.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Clinical Neurology
Joao Vale, Eduardo Rocha, Carolina Lemos, Cristina Valente, Renato Andrade, Joao Espregueira-Mendes, Ricardo Rodrigues-Pinto
Summary: This study evaluated the role of systemic steroids in treating sciatica in patients with lumbar disk herniation through a systematic review and meta-analysis. The results showed that systemic steroids can significantly reduce pain and disability, but their use is associated with an increased risk of adverse events.
Article
Clinical Neurology
Frederick P. Mariajoseph, Mendel Castle-Kirszbaum, Jeremy Kam, Myron Rogers, Reece Sher, Chris Daly, Jack Roadley, Phillipa Risbey, Kylie Fryer, Tony Goldschlager
Summary: This study found no correlation between herniated disc fragment weight and severity of preoperative or postoperative pain. Regardless of the size of lumbar disc herniation, patients benefit equally from surgery.
JOURNAL OF CLINICAL NEUROSCIENCE
(2022)
Article
Clinical Neurology
Bilal Tarabay, Fares Komboz, Sandra Kobaiter-Maarrawi, Fouad Fayad, Hicham Abou Zeid, Joseph Maarrawi
Summary: The study aims to assess the effectiveness of PTX in the treatment of radicular pain caused by lumbar disc herniation. The results show that adding PTX to the treatment protocol significantly reduces patients' pain intensity and improves their overall satisfaction with treatment.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2022)
Article
Medicine, General & Internal
Min Jong Ki, Cheol Jong Woo, Yu Jin Oh, Seon Hwa Nam, A. Ram Doo
Summary: This report presents two unusual cases of herniation of the thoracic intervertebral disc (HTD). One patient had abdominal bulging with atrophy of the abdominal wall muscles, while the other patient had aggravated postherpetic neuralgia. Both patients experienced significant pain reduction after treatment.
Article
Neurosciences
Savas Sencan, Alp Eren Celenlioglu, Gonca Yazici, Osman Hakan Gunduz
Summary: TFESI is an effective and safe method to decrease not only nociceptive but also NP component in patients with chronic radiculopathy due to LDH, leading to significant improvement in patients' pain levels and quality of life.
Article
Integrative & Complementary Medicine
Je-Heon Noh, Da-young Byun, Si-hoon Han, Jeongyoon Kim, Ji-ae Roh, Min-Young Kim, Su-na Kim, Eun-San Kim, Kyoung Sun Park, Jinho Lee, In-Hyuk Ha
Summary: The study found that the application of motion style acupuncture treatment (MSAT) on the pelvic joint can improve the symptoms of herniated lumbar disc with radiating leg pain and improve the quality of life.
EXPLORE-THE JOURNAL OF SCIENCE AND HEALING
(2022)
Review
Clinical Neurology
E. J. A. Verheijen, C. A. Bonke, E. M. J. Amorij, C. L. A. Vleggeert-Lankamp
Summary: Epidural steroid injections (ESI) show greater improvements in leg pain and functional status for sciatica patients compared to epidural placebo injections in the short term. However, there is no significant difference in back pain outcomes. Some studies suggest ESI can reduce analgesic intake with low complication rates.
EUROPEAN SPINE JOURNAL
(2021)
Review
Medicine, General & Internal
Andrew S. Zhang, Andrew Xu, Kashif Ansari, Kyle Hardacker, George Anderson, Daniel Alsoof, Alan H. Daniels
Summary: Lumbar disc herniations are a common cause of lower back pain, neurological dysfunction, and buttock/leg pain. Diagnosis is achieved through a thorough history, physical examination, and advanced imaging. Most patients can find relief with nonsurgical treatments, but surgery may be necessary for persistent or worsening symptoms.
AMERICAN JOURNAL OF MEDICINE
(2023)
Review
Anesthesiology
Ryan D. Morgan, Abdurrahman F. Kharbat, Gabor Racz, Laszlo Nagy
Summary: The anterior epidural space volume is smaller in the pediatric population compared to adults. This may contribute to the increased failure of conservative treatment for pediatric lumbar disc herniations.
Review
Anesthesiology
Laxmaiah Manchikanti, Emilija Knezevic, Nebojsa Nick Knezevic, Brahma Prasad Vangala, Mahendra R. Sanapati, Srinivasa Thota, Salahadin Abdi, Alaa Abd-Elsayed, Alan D. Kaye, Joshua A. Hirsch
Summary: The Best Practices in Pain Management from the U.S. Department of Health and Human Services highlight the importance of interventional techniques in pain management, with epidural injections being a common modality for managing low back and lower extremity pain. Different approaches of epidural injections have varying efficacy, with limited comparative assessment research currently available.
Article
Clinical Neurology
Jacob B. Cordover, Glenn S. Fleisig, Jesse A. Raszewskr, Aaron S. Dumone, Andrew M. Cordover
Summary: This study evaluated the return to play rate for young athletes after lumbar microdiscectomy and found a good prognosis. The return to play rate and Pfirrmann grade were not related to gender, sport level, or discectomy level.
WORLD NEUROSURGERY
(2022)
Review
Anesthesiology
Laxmaiah Manchikanti, Emilija Knezevic, Richard E. Latchaw, Nebojsa Nick Knezevic, Salahadin Abdi, Mahendra R. Sanapati, Peter S. Staats, Christopher G. Gharibo, Thomas T. Simopoulos, Shalini Shah, Alaa Abd-Elsayed, Annu Navani, Alan D. Kaye, Sheri L. Albers, Joshua A. Hirsch
Summary: A reanalysis of the Cochrane Review data suggests that epidural injections are effective in managing chronic low back and lower extremity pain. However, there are conflicting views on the effectiveness of epidural injections in different systematic reviews and meta-analyses.
Article
Anesthesiology
Ludger Gerdesmeyer, Carl Noe, Alexander Prehn-Kristensen, Norbert Harrasser, Munjed Al Muderis, Matthias Weuster, Tim Klueter
Summary: This study provides a 10-year follow-up report of a placebo-controlled RCT showing efficacy of minimally invasive percutaneous adhesiolysis for chronic lumbosacral radicular pain. The results demonstrate significant improvement in pain and disability scores in the treatment group compared to the control group at 1 and 10 years. The procedure is considered as the first treatment option for patients with chronic lumbosacral radicular pain.
Review
Clinical Neurology
Anais Gouteron, Anne Tabard-Fougere, Abderrahmane Bourredjem, Jean-Marie Casillas, Stephane Armand, Stephane Genevay
Summary: This systematic review synthesized the current knowledge on the flexion relaxation phenomenon (FRP) in the nonspecific chronic low back pain (NSCLBP) population. The results showed that altered FRP is frequently found in NSCLBP patients using surface electromyography (sEMG) and the test has good reproducibility. There was a significant difference between asymptomatic individuals and NSCLBP patients in terms of flexion relaxation ratio (FRR), but further research is needed to confirm the value of FRP due to high heterogeneity.
EUROPEAN SPINE JOURNAL
(2022)
Article
Clinical Neurology
Stefanos Voglis, Alexander Romagna, Menno R. Germans, Isaac Carreno, Martin N. Stienen, Anna Henzi, Katrin Frauenknecht, Elisabeth Rushing, Granit Molliqaj, Kayee Tung, Enrico Tessitore, Howard J. Ginsberg, David Bellut
Summary: Spinal arachnoid web (SAW) is a rare condition characterized by focal thickening of the arachnoid membrane causing displacement and compression of the spinal cord, with unique clinical and radiographic features. Surgical treatment of SAW can lead to significant improvement in long-term outcomes, emphasizing the importance of correct diagnosis and timely intervention.
Article
Rheumatology
Denis Mongin, Kim Lauper, Axel Finckh, Thomas Frisell, Delphine Sophie Courvoisier
Summary: This study assessed the performance of statistical methods used to compare drug effectiveness in the presence of attrition. The results showed that only multiple imputation and inverse probability weighting, which considered both confounding and treatment cessation reasons, produced accurate comparative effectiveness estimates.
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Article
Clinical Neurology
Florian Bailly, Stephane Genevay, Violaine Foltz, Amelie Bohm-Sigrand, Alain Zagala, Julien Nizard, Audrey Petit
Summary: The study found that during the COVID-19 lockdown, chronic LBP patients experienced worsened LBP, decreased physical activity, and increased sedentary behavior. A positive lockdown experience was associated with LBP improvement, while decreased physical activity was linked to worsening LBP.
EUROPEAN SPINE JOURNAL
(2022)
Article
Neurosciences
Florent Moissenet, Anne Tabard-Fougere, Stephane Genevay, Stephane Armand
Summary: This study evaluated the impact of normalisation tasks on the quality and reliability of RF EMG signals. The results showed that using ISO-H for normalisation resulted in higher consistency, but %SEM remained high regardless of the task used, indicating potential need for further improvements.
Article
Orthopedics
Gianpaolo Jannelli, Alessandro Moiraghi, Luca Paun, Victor Cuvinciuc, Andrea Bartoli, Enrico Tessitore
Summary: The study retrospectively analyzed the accuracy and reliability of posterior atlanto-axial fixation using spinal navigation combined with intra-operative 3D isocentric C-arm. The results showed that all cases achieved acceptable screw positioning, with no vertebral artery injury observed and no screw loosening or displacement at three-month follow-up.
INTERNATIONAL ORTHOPAEDICS
(2022)
Editorial Material
Rheumatology
Ilias Lazarou, Lucia Calisto Farracho, Stephane Genevay, Michele Iudici
JOURNAL OF RHEUMATOLOGY
(2022)
Review
Clinical Neurology
Guillaume Baucher, Jelena Taskovic, Lucas Troude, Granit Molliqaj, Aria Nouri, Enrico Tessitore
Summary: Degenerative cervical myelopathy (DCM) is considered the most common cause of spinal cord dysfunction among adults, potentially influenced by various factors. Age, cervical alignment, range of motion, and certain congenital conditions have been found to be associated with the risk of DCM. Other factors such as smoking, participation in contact sports, have also been suggested as potential risks for myelopathy development.
NEUROSURGICAL REVIEW
(2022)
Article
Medicine, General & Internal
Mohammad Ghafouri, Azin Teymourzadeh, Amin Nakhostin-Ansari, Sadaf G. Sepanlou, Sahar Dalvand, Farhad Moradpour, Amir Hooshang Bavarsad, Shahrokh Sadeghi Boogar, Morteza Dehghan, Alireza Ostadrahimi, Javad Aghazadeh-Attari, Mahmood Kahnooji, Ali Hosseinipour, Ali Gohari, Seyed Vahid Hosseini, Masoud Mirzaei, Alireza Khorram, Mehdi Shahmoradi, Farhad Pourfarzi, Mahmood Moosazadeh, Fariborz Mansour-Ghanaei, Hossein Marioryad, Farid Najafi, Stephane Genevay, Navid Moghadam, Ramin Kordi
Summary: This study aimed to evaluate the prevalence and factors associated with low back pain (LBP) among the Iranian population. The results showed that female gender, older age, being overweight or obese, smoking history, low physical activity, and short sleep duration were significantly associated with LBP. The study found a lower lifetime prevalence of LBP among Iranians compared to global prevalence.
ANNALS OF MEDICINE AND SURGERY
(2022)
Article
Medicine, General & Internal
Mayssam Nehme, Olivia Braillard, Francois Chappuis, Delphine S. Courvoisier, Laurent Kaiser, Paola M. Soccal, Jean-Luc Reny, Frederic Assal, Guido Bondolfi, Aglae Tardin, Christophe Graf, Dina Zekry, Silvia Stringhini, Herve Spechbach, Frederique Jacquerioz, Julien Salamun, Frederic Lador, Matteo Coen, Thomas Agoritsas, Lamyae Benzakour, Riccardo Favale, Stephane Genevay, Kim Lauper, Philippe Meyer, Nana K. Poku, Basile N. Landis, Stephanie Baggio, Marwene Grira, Jose Sandoval, Julien Ehrsam, Simon Regard, Camille Genecand, Garance Kopp, Ivan Guerreiro, Gilles Allali, Pauline Vetter, Idris Guessous
Summary: Persistent symptoms, including fatigue, dyspnea, headache, insomnia, and difficulty concentrating, can be observed in COVID-19 patients up to 12 months after infection. Functional impairment is also commonly reported in these individuals. These symptoms have the potential to significantly impact an individual's quality of life.
JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Rheumatology
L. van Boheemen, M. M. Ter Wee, M. Falahee, A. Filer, M. Van Beers-Tas, A. Finckh, A. Hensvold, K. Raza, D. van Schaardenburg
Summary: This study aimed to define symptom characteristics associated with rheumatoid arthritis (RA) development in at-risk individuals and investigate the differences in predictive symptoms between seropositive and seronegative at-risk individuals. Through questionnaire and follow-up, specific symptoms were found to predict the development of arthritis.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
(2023)
Article
Multidisciplinary Sciences
Mayssam Nehme, Olivia Braillard, Francois Chappuis, Idris Guessous
Summary: This study found that 10-35% of COVID-19 cases in outpatient settings develop post-COVID condition. The duration and severity of symptoms contribute to the complexity and heterogeneity of post-COVID condition. Patients with chronic symptoms experience increased healthcare utilization, treatment needs, functional impairment, and poorer quality of life. Having multiple symptoms and difficulty concentrating at 7 months after infection are associated with a chronicity of symptoms.
SCIENTIFIC REPORTS
(2022)
Article
Immunology
Mayssam Nehme, Pauline Vetter, Francois Chappuis, Laurent Kaiser, Idris Guessous
Summary: This study evaluates the prevalence of symptoms and functional impairment 12 weeks after Omicron variants (BA.1 and BA.2) infection and compares it with negative controls. The results show that the prevalence of symptoms after 12 weeks of Omicron infection is relatively low, and vaccination can reduce the occurrence of post-COVID symptoms.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Neurosciences
Anais Gouteron, Anne Tabard-Fougere, Florent Moissenet, Abderrahmane Bourredjem, Kevin Rose-Dulcina, Stephane Genevay, Davy Laroche, Stephane Armand
Summary: This study investigates the sensitivity and specificity of different methods used to calculate flexion relaxation ratio (FRR) and extension relaxation ratio (ERR) in identifying an altered flexion relaxation phenomenon in nonspecific chronic low back pain patients. The results show that all methods used for calculating these ratios are highly sensitive and specific.
JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY
(2023)
Article
Clinical Neurology
Ali Ahmadzadeh Amiri, Stephane Genevay, Amir Ahmadzadeh Amiri, Fatemeh Daneshvar, Jamshid Yazdani Charati, Mohammad Ghafouri, Navid Moghadam, Ramin Kordi
Summary: This study aimed to evaluate the effectiveness of providing a back care package through the primary healthcare system in decreasing the rate of chronic low back pain (CLBP) in the community. The intervention group showed a statistically significant decrease in both the prevalence and incidence of CLBP, compared to the control group.