Article
Orthopedics
Yuqi Yang, Zhengquan Chen, Zefan Huang, Jing Tao, Xin Li, Xuan Zhou, Qing Du
Summary: This review investigates the risk factors of low bone mineral density (BMD) in children with idiopathic scoliosis (IS). The findings suggest that genetic, endocrine, and lifestyle-related factors may be associated with low BMD and osteoporosis in IS patients. Further research is needed to evaluate the effectiveness of screening for low BMD risk factors and develop intervention strategies for bone health.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Medicine, General & Internal
Jakub Glowacki, Joanna Latuszewska, Adam Okret, Natalia Skowron, Ewa Misterska, Justyna Opydo-Szymaczek
Summary: Patients with adolescent idiopathic scoliosis (AIS) treated with a Milwaukee brace for at least 23 years show higher levels of temporomandibular joint disorders (TMD) compared to healthy controls, with clinical and radiological factors influencing the results and indicating limitations in everyday activities related to the temporomandibular joint.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Pharmacology & Pharmacy
Jiangbi Li, Yang Sun, Zhuo Chen, Xiaoping Xie, Feng Gu, Songqi Bi, Tiecheng Yu
Summary: This review examined the effects of bisphosphonates on bone density, fractures, and bone markers in osteopenic older women. The study found that bisphosphonates had significant positive effects on bone density and bone markers, as well as reducing the risk of fractures. However, further research is needed to determine their safety.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Laura Bautista-Aguilar, Clementina Lopez-Medina, Lourdes Ladehesa-Pineda, Maria del Carmen Abalos-Aguilera, Desiree Ruiz-Vilchez, Juan Luis Garrido-Castro, Ignacio Gomez-Garcia, Maria Angeles Puche-Larrubia, Asuncion Salmoral-Chamizo, Eduardo Collantes-Estevez, Alejandro Escudero-Contreras, Pilar Font-Ugalde
Summary: The study assessed the prevalence of low bone mineral density in the total hip or femoral neck in axial spondyloarthritis patients. Results showed 36% had low BMD and 56% had osteopenia. Age and radiographic sacroiliitis were the most important factors associated with decreased BMD.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Environmental Sciences
Ming Qin, Yue Gao, Meichen Zhang, Junhua Wu, Yang Liu, Yuting Jiang, Xiaodi Zhang, Xin Wang, Yanmei Yang, Yanhui Gao
Summary: This study investigates the effects of fluorine and ADAMTS14_rs4747096 on bone mineral density (BMD). The findings suggest that fluoride exposure and mutation G allele in ADAMTS14_rs4747096 may be risk factors for decreased BMD, and there is an interaction between the two influencing factors.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Medicine, General & Internal
Hongfei Wang, Teng Zhang, Changmeng Zhang, Liangyu Shi, Samuel Yan-Lik Ng, Ho-Cheong Yan, Karen Ching-Man Yeung, Janus Siu-Him Wong, Kenneth Man-Chee Cheung, Graham Ka-Hon Shea
Summary: This study developed a machine learning-based prediction model to accurately predict the risk of progression in adolescent idiopathic scoliosis (AIS) curves. By integrating clinical data, X-rays, and hand X-rays, the model can predict the risk of curve progression at the first clinic visit.
Article
Medicine, General & Internal
Hongqi Zhang, Guanteng Yang, Jiong Li, Lige Xiao, Chaofeng Guo, Yuxiang Wang
Summary: This study found that BMSCs from AIS-related osteopenia patients have lower autophagic activity, which is related to their lower osteogenic capacity and higher adipogenic capacity.
CHINESE MEDICAL JOURNAL
(2023)
Article
Medicine, General & Internal
Zhichong Wu, Xiufen Zhu, Leilei Xu, Zhen Liu, Zhenhua Feng, Vivian Wing Yin Hung, Jack Chun Yiu Cheng, Yong Qiu, Wayne Y. W. Lee, Tsz Ping Lam, Zezhang Zhu
Summary: The prevalence of low bone-mineral density (BMD) is higher in boys with severe adolescent idiopathic scoliosis (AIS) than in girls. Factors such as sex, body mass index, serum alkaline phosphatase, and potassium are independent risk factors of low BMD in severe AIS patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Orthopedics
Li Cao, Wei Wu, Xiangyu Deng, Haoyu Guo, Feifei Pu, Zengwu Shao
Summary: This study examined the relationship between total cholesterol and total bone mineral density (BMD) among 10,039 US participants. The results showed a negative correlation between total cholesterol levels and total BMD among participants aged 20-29 years. In other races, this relationship exhibited a nonlinear association, with an inflection point. Therefore, maintaining a reasonable total cholesterol level may be an approach to prevent osteoporosis or osteopenia in young adults and individuals with diabetes.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Multidisciplinary Sciences
Kyung Eun Nam, Irian Kim, Hae-Yeon Park, Jong In Lee
Summary: This study investigated the long-term effects of breast cancer surgery on spinal alignment and found that most breast cancer patients experience minimal changes in spinal alignment after surgery.
Article
Pediatrics
Tugba Kuru Colak, Burcin Akcay, Adnan Apti, Ilker Colak
Summary: This study aimed to present the long-term effects of a conservative management method, including exercise and brace, in patients with adolescent idiopathic scoliosis. The results showed that appropriate conservative treatment can successfully halt the progression of idiopathic scoliosis in growing adolescents and long-term improvement is largely maintained.
Review
Immunology
Miriam Cox, Robert D. Sandler, Marco Matucci-Cerinic, Michael Hughes
Summary: Review of literature on bone health in patients with idiopathic inflammatory myopathies (IIM) showed high prevalence of osteopenia, osteoporosis, and vertebral fractures. Systemic inflammation may contribute to reduced bone mineral density in children with IIM, while data is lacking for adult patients. Further research is needed to develop specific management recommendations for bone health in IIM patients.
AUTOIMMUNITY REVIEWS
(2021)
Article
Nutrition & Dietetics
Mariangela Rondanelli, Milena Anna Faliva, Gaetan Claude Barrile, Alessandro Cavioni, Francesca Mansueto, Giuseppe Mazzola, Letizia Oberto, Zaira Patelli, Martina Pirola, Alice Tartara, Antonella Riva, Giovanna Petrangolini, Gabriella Peroni
Summary: This review evaluates the ideal dietary approach to reduce bone mineral density loss and suggests a food pyramid for osteopenia/osteoporosis patients. The pyramid emphasizes daily consumption of carbohydrates, fruits, vegetables, light yogurt, skim milk, extra virgin olive oil, and calcium water. Weekly portions include fish, white meat, legumes, eggs, cheeses, and red/processed meats. The pyramid also highlights the need for personalized supplementation and identifies certain foods to be avoided. Additionally, regular aerobic and resistance exercises are recommended.
Article
Clinical Neurology
Omar Ramos, Jacob Razzouk, Jun Ho Chung, Wayne K. Cheng, Olumide A. Danisa
Summary: Patients with Adolescent Idiopathic Scoliosis (AIS) have lower bone density compared to healthy adolescents, and MRI can be used to assess bone quality in AIS patients.
JOURNAL OF CLINICAL NEUROSCIENCE
(2022)
Article
Endocrinology & Metabolism
Yang Xu, Li Shen, Lianyong Liu, Zhenlin Zhang, Weiwei Hu
Summary: This study investigated the profile of serum undercarboxylated osteocalcin (ucOC) levels and their associations with bone mineral density (BMD), bone turnover markers (BTMs), and prevalence of osteopenia and osteoporosis in the Chinese population. The results showed that ucOC levels were higher in men than women and decreased with age until the age of 50, after which they increased. Higher ucOC levels were correlated with lower BMD values and higher levels of BTMs in both men and women. Furthermore, an increase in ucOC levels was associated with an increased risk of osteopenia and osteoporosis in both genders.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Engineering, Biomedical
Sien Lin, Liao Cui, Guanghua Chen, Jianping Huang, Yanhua Yang, Kaijie Zou, Yuxiao Lai, Xinluan Wang, Liyi Zou, Tie Wu, Jack Chun Yiu Cheng, Gang Li, Bo Wei, Wayne Yuk Wai Lee
Article
Clinical Neurology
Fei Sheng, Chao Xia, Leilei Xu, Xiaodong Qin, Nelson Leung-Sang Tang, Yong Qiu, Jack Chun-Yiu Cheng, Zezhang Zhu
Article
Clinical Neurology
Gene Chi-Wai Man, Nelson Leung-Sang Tan, Ting Fung Chan, Tsz Ping Lam, Jing Woei Li, Bobby Kin-Wah Ng, Zezhang Zhu, Yong Qiu, Jack Chun-Yiu Cheng
Article
Multidisciplinary Sciences
Hao Liu, Zhen Liu, Chi-wai Man, Jing Guo, Xiao Han, Zongshan Hu, Tzi Bun Ng, Zhihui Zhao, Jie Li, Weijun Wang, Tseng-chang Chun, Jun Qiao, Benlong Shi, Leilei Xu, Hongda Bao, Qing Jiang, Tsz Ping Lam, Jack Chun Yiu Cheng, Yong Qiu, Zezhang Zhu
SCIENTIFIC REPORTS
(2019)
Article
Endocrinology & Metabolism
Ka Yee Cheuk, Yizhong Hu, Elisa M. S. Tam, Lin Shi, Fiona W. P. Yu, Vivian W. Y. Hung, Kevin Cheuk Yin Lai, Wilson Ho Wu Cheng, Benjamin H. K. Yip, Ling Qin, Bobby K. W. Ng, Winnie C. W. Chu, James Griffith, X. Edward Guo, Jack C. Y. Cheng, Tsz Ping Lam
ARCHIVES OF OSTEOPOROSIS
(2019)
Article
Biochemistry & Molecular Biology
Huanxiong Chen, Jiajun Zhang, Yujia Wang, Ka-Yee Cheuk, Alec L. H. Hung, Tsz-Ping Lam, Yong Qiu, Jian Q. Feng, Wayne Y. W. Lee, Jack C. Y. Cheng
Article
Acoustics
Yi-Shun Wong, Kelly Ka-Lee Lai, Yong-Ping Zheng, Lyn Lee-Ning Wong, Bobby Kin-Wah Ng, Alec Lik-Hang Hung, Benjamin Hon-Kei Yip, Winnie Chiu-Wing Chu, Alex Wing-Hung Ng, Yong Qiu, Jack Chun-Yiu Cheng, Tsz-Ping Lam
ULTRASOUND IN MEDICINE AND BIOLOGY
(2019)
Article
Multidisciplinary Sciences
Gene Chi-Wai Man, Elisa Man-Shan Tam, Yi Shun Wong, Vivian Wing-Ying Hung, Zongshan Hu, Tsz Ping Lam, Zhen Liu, Wing Hoi Cheung, Tzi Bun Ng, Zezhang Zhu, Yong Qiu, Jack Chun-Yiu Cheng
SCIENTIFIC REPORTS
(2019)
Article
Biochemistry & Molecular Biology
Man-Huen Victoria Choy, Ronald Man-Yeung Wong, Meng-Chen Li, Bai Yan Wang, Xiao Dong Liu, Wayne Lee, Jack Chun-Yiu Cheng, Simon Kwoon-Ho Chow, Wing-Hoi Cheung
Article
Medicine, General & Internal
Yujia Wang, Huanxiong Chen, Jiajun Zhang, Tsz-ping Lam, A. L. H. Hung, J. C. Y. Cheng, W. Y. W. Lee
Summary: This study found elevated levels of muscle structural proteins in progressive adolescent idiopathic scoliosis (AIS) patients, suggesting the likelihood of microscopic structural damage and its association with progression to the surgical threshold.
JOURNAL OF CLINICAL MEDICINE
(2021)
Meeting Abstract
Endocrinology & Metabolism
Yujia Wang, Ka-Lo Cheng, Jiajun Zhang, Tsz-ping Lam, Alec L. H. Hung, Jack C. Y. Cheng, Wayne Y. W. Lee, Zhenhua Feng, Leilei Xu, Yong Qiu
JOURNAL OF BONE AND MINERAL RESEARCH
(2019)
Meeting Abstract
Endocrinology & Metabolism
Jiajun Zhang, Kayee Cheuk, Yujia Wang, Ka-lo Cheng, Tsz-ping Lam, Bobby Kin Wah Ng, Jack Chun Yiu Cheng, Wayne Yuk-wai Lee, Yong Qiu
JOURNAL OF BONE AND MINERAL RESEARCH
(2019)
Article
Biochemistry & Molecular Biology
Leilei Xu, Zhichong Wu, Chao Xia, Nelson Tang, Jack C. Y. Cheng, Yong Qiu, ZeZhang Zhu
Article
Orthopedics
L. C. M. Lau, A. L. H. Hung, W. W. Chau, Z. Hu, A. Kumar, T. P. Lam, W. C. W. Chu, J. C. Y. Cheng
JOURNAL OF CHILDRENS ORTHOPAEDICS
(2019)
Article
Cell & Tissue Engineering
R. M. Y. Wong, U. Thormann, M. H. Choy, Y. N. Chim, M. C. M. Li, J. Y. Wang, K. S. Leung, J. C. Y. Cheng, V Alt, S. K. H. Chow, W. H. Cheung
EUROPEAN CELLS & MATERIALS
(2019)