Review
Nutrition & Dietetics
Farah J. Alsharif, Yara A. Almuhtadi
Summary: With the global prevalence of obesity increasing dramatically, it has become a serious public health threat associated with comorbid conditions and psychological disorders. While lifestyle interventions and dietary adjustments may help with weight loss, maintaining these changes long-term can be challenging. Spices like turmeric, ginger, and pepper have shown promise in obesity management, with curcumin in particular gaining interest for its health benefits. Studies have shown potential favorable effects of curcumin supplementation on anthropometric indices, warranting further investigation for overweight or obese adults.
Article
Medicine, General & Internal
Alexandre Mazeas, Aina Chalabaev, Marine Blond, Bruno Pereira, Martine Duclos
Summary: This study aims to evaluate the effectiveness of a group-based digital intervention grounded on gamification strategies, enhanced by social features, for obese and patients with type 2 diabetes mellitus (T2DM). The study will explore psychological mediators and conduct a cost-utility analysis to assess the potential economic efficiency of the intervention.
Review
Nutrition & Dietetics
Valentina V. Huwiler, Katja A. Schonenberger, Alexander Segesser von Brunegg, Emilie Reber, Stefan Muhlebach, Zeno Stanga, Maria L. Balmer
Summary: The prevalence of overweight and obesity is rapidly increasing worldwide. Supplementation with isolated soluble dietary fiber shows promise in weight loss and reducing metabolic complications in overweight and obese individuals. This study conducted a systematic review and meta-analysis, finding that dietary fiber supplementation significantly reduces body weight, BMI, waist circumference, fasting blood insulin, and HOMA-IR levels. The evidence certainty is high, suggesting the implementation of isolated soluble dietary fiber supplementation in clinical practice.
Article
Pharmacology & Pharmacy
Kyungha Min, Bumjo Oh, Hye Yeon Koo, Yang-Hyun Kim, Ji-Won Lee, Sangsub Lee, Youngah Kim, Hyuktae Kwon
Summary: Glaceum Inc. plans to conduct a randomized, double-blind, placebo-controlled clinical trial to evaluate the safety and efficacy of HSG4112 in overweight and obese patients.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Nutrition & Dietetics
Kerstin Kempf, Martin Roehling, Hubert Kolb, Stephan Martin
Summary: The study analyzed the effects of two different breads on body weight without further lifestyle modification. It found that replacing a common insulinogenic bread with a low-insulin-stimulating bread can lead to significant weight loss, especially for overweight individuals, particularly those at older age.
Article
Integrative & Complementary Medicine
Eduardo Cabrera-Rode, Ileana Cubas-Duenas, Janet Rodriguez Acosta, Jeddu Cruz Hernandez, Ana Ibis Conesa Gonzalez, Teresa M. Gonzalez Calero, Yuri Arnold Dominguez, Jose Hernandez Rodriguez, Antonio D. Reyes Rodriguez, Aimee Alvarez Alvarez, Ragmila Echevarria Valdes, Liudmila Jorge Espinosa, Onelia Torres Belent, Zoila Bell Benavides, Elizabeth Senra Estevez, Yanet Abreu Rodriguez, Juana del Valle Rodriguez, Silvia Marin Julia
Summary: This study suggests that Obex(R) may be helpful in reducing body weight and fat. Through a randomized double-blind clinical trial, researchers found that Obex(R) combined with non-pharmacological treatment significantly improved weight, waist circumference, and insulin metabolism in overweight and obese patients. Compared to the placebo group, the Obex(R) group had higher levels of high-density lipoprotein cholesterol.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2023)
Article
Multidisciplinary Sciences
Peter Hajek, Dunja Przulj, Francesca Pesola, Hayden McRobbie, Sarrah Peerbux, Anna Phillips-Waller, Natalie Bisal, Katie Myers Smith
Summary: The study found that the 5:2 diet and standard multicomponent weight management advice yielded similar weight loss results, with the 5:2 diet not undermining other health behaviors and receiving more positive ratings. Additionally, adding initial group support enhanced adherence and effects of the 5:2 diet.
Article
Nutrition & Dietetics
Faidon Magkos, Sidse Rasmussen, Mads F. Hjorth, Sarah Asping, Maria Rosenkrans, Anders M. Sjodin, Arne Astrup, Nina R. W. Geiker
Summary: This study found that healthy diets containing small or large amounts of unprocessed beef had similar effects on body weight, energy metabolism, and cardiovascular risk factors during the first 3 months after clinically significant rapid weight loss.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Medicine, General & Internal
Xiaofan Jing, Yuxiang Liang, Renjie Wang, Hongbo Fu, Jiaojiao Jiang, Ming Yang
Summary: Obesity is a global public health challenge, and dietary supplements that can improve muscle mass and function are needed. This study aims to evaluate the effectiveness and safety of HMB-enriched nutritional supplements in obese adults during calorie restriction, focusing on muscle mass and muscle function.
Article
Integrative & Complementary Medicine
Hyang-Im Baek, Ki-Chan Ha, Yu Kyung Park, Je Hyeon Lee, Eun Joo Kim, Hye-Jeong Ko, Jong Cheon Joo
Summary: This study found that the use of NAOs significantly reduces visceral fat area and the ratio of visceral-subcutaneous fat area. Compared to the placebo group, the NAOs group showed smaller increases in weight and BMI. Additionally, the NAOs group had an increase in high-density lipoprotein-cholesterol levels. No clinical changes were observed for any safety biomarkers.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2023)
Article
Medicine, General & Internal
Ying Zhang, Yang Yi, Guoping Xiong, Fen Yu
Summary: This study aims to systematically assess the effects of regular exercise for overweight and obese gravidas, providing clinical guidance for this population.
Article
Medicine, General & Internal
Karen P. Best, Jacqueline F. Gould, Maria Makrides, Thomas Sullivan, Jeanie Cheong, Shao J. Zhou, Stefan Kane, Huda Safa, A. Sparks, Lex W. Doyle, A. J. McPhee, Tanya A. C. Nippita, Hossein H. A. Afzali, Rosalie Grivell, D. Mackerras, E. Knight, Simon Wood, Tim Green
Summary: This study aims to determine the effect of reducing iodine intake from supplements on the cognitive development of children at 24 months of age. A total of 754 pregnant women will be randomly assigned to receive either a low iodine or a common dose of iodine supplement. The primary outcome is the developmental quotient of infants at 24 months of age.
Article
Medicine, General & Internal
Mohamed Taher, Christina Yule, Heather Bonaparte, Sara Kwiecien, Charlotte Collins, Allison Naylor, S. P. Juraschek, Lisa Bailey-Davis, Alex R. Chang
Summary: This study aims to compare the efficacy of telehealth and self-directed lifestyle intervention in lowering 24-hour systolic blood pressure in overweight/obese patients. All participants receive personalized dietary recommendations, access to an online weight management program and a smartphone dietary app. The telehealth arm also includes weekly calls with registered dietitian nutritionists.
Article
Nutrition & Dietetics
Abrar M. Babateen, Oliver M. Shannon, Gerard M. O'Brien, Edward Okello, Anmar A. Khan, Sofia Rubele, Emma Wightman, Ellen Smith, Nicholas McMahon, Dilara Olgacer, Christina Koehl, William Fostier, Ines Mendes, David Kennedy, John C. Mathers, Mario Siervo
Summary: The study found that prolonged consumption of beetroot juice is feasible in older overweight and obese adults, leading to increased nitric oxide production and improved health outcomes. Compliance with the interventions was high, indicating potential benefits of nitrate-rich foods on vascular and brain functions.
Article
Medicine, General & Internal
Juan P. Frias, Srikanth Deenadayalan, Lars Erichsen, Filip K. Knop, Ildiko Lingvay, Stanislava Macura, Chantal Mathieu, Sue Pedersen, Melanie Davies
Summary: This study assessed the efficacy and safety of co-administered semaglutide with cagrilintide in participants with type 2 diabetes. The results showed that the combination treatment resulted in clinically relevant improvements in glycemic control and weight loss compared to cagrilintide alone, and it was well tolerated.
Review
Nutrition & Dietetics
A. Strozyk, Z. Osica, J. D. Przybylak, M. Kolodziej, B. M. Zalewski, B. Mrozikiewicz-Rakowska, H. Szajewska
JOURNAL OF HUMAN NUTRITION AND DIETETICS
(2019)
Review
Nutrition & Dietetics
Bernadeta Patro-Golab, Hania Szajewska
Review
Gastroenterology & Hepatology
Hania Szajewska, Maciej Kolodziej, Bartlomiej M. Zalewski
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2020)
Review
Nutrition & Dietetics
Jeadran N. Malagon-Rojas, Anastasia Mantziari, Seppo Salminen, Hania Szajewska
Article
Gastroenterology & Hepatology
Hania Szajewska, Alfredo Guarino, Iva Hojsak, Flavia Indrio, Sanja Kolacek, Rok Orel, Silvia Salvatore, Raanan Shamir, Johannes B. van Goudoever, Yvan Vandenplas, Zvi Weizman, Bartlomiej M. Zalewski
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2020)
Review
Microbiology
Anastasia Mantziari, Seppo Salminen, Hania Szajewska, Jeadran Nevardo Malagon-Rojas
Review
Nutrition & Dietetics
Katarzyna Babik, Bernadeta Patro-Golab, Bartlomiej M. Zalewski, Katarzyna Wojtyniak, Pawel Ostaszewski, Andrea Horvath
Summary: This systematic review evaluated the association of breastfeeding duration, timing of complementary feeding introduction, and feeding techniques with feeding difficulties in children older than 1 year of age. The results showed that longer duration of breastfeeding tended to be associated with fewer childhood feeding problems, while the association between timing of complementary feeding introduction and feeding difficulties was inconsistent. Additional methodologically rigorous studies are needed to confirm these findings.
Article
Nutrition & Dietetics
Andrea Horvath, Agata Strozyk, Piotr Dziechciarz, Hania Szajewska
Summary: This study in Poland investigated how COVID-19 pandemic restrictions impacted complementary feeding practices among parents of infants aged 4 to 12 months. Results showed that most parents received information from various sources, with other parents, family members, or friends being the most common source. The study found that COVID-19 restrictions did not significantly affect feeding methods or patterns, but may have had an impact on complementary feeding in families with average financial situations.
Review
Nutrition & Dietetics
Alessandro Fiocchi, Jan Knol, Sibylle Koletzko, Liam O'Mahony, Nikolaos G. Papadopoulos, Seppo Salminen, Hania Szajewska, Anna Nowak-Wegrzyn
Summary: Acute respiratory infections are a common cause of morbidity in infants and young children, impacting healthcare resources and antibiotic use, and potentially leading to antibiotic resistance and changes in intestinal microbiota composition. Through international collaboration, researchers are exploring the links between infant feeding, cow's milk allergy, and infection risk, with a focus on strategies to improve infection outcomes and reduce antibiotic usage in vulnerable populations like infants with CMA.
Review
Nutrition & Dietetics
Hania Szajewska, Raanan Shamir, Anna Chmielewska, Agata Strozyk, Bartlomiej M. Zalewski, Renata Auricchio, Sibylle Koletzko, Ilma R. Korponay-Szabo, Luisa Mearin, Caroline Meijer, Carmen Ribes-Koninckx, Riccardo Troncone
Summary: This study aims to investigate the association between early feeding practices and the risk of developing celiac disease (CD) in infants genetically predisposed to CD. It will analyze randomized controlled trials and observational studies, with the primary outcome measure being CD or CD autoimmunity. The findings will be submitted to a peer-reviewed journal.
Article
Nutrition & Dietetics
Yvan Vandenplas, Katerina Bajerova, Christophe Dupont, Philippe Eigenmann, Mikael Kuitunen, Rosan Meyer, Carmen Ribes-Koninckx, Silvia Salvatore, Raanan Shamir, Hania Szajewska
Summary: CoMiSS was developed 7 years ago as a tool to increase awareness among healthcare professionals about the possibility of infant symptoms being related to cow's milk. Based on extensive research, an updated CoMiSS with lowered required cutoff and adaptation for non-toilet trained children has been proposed. However, further studies are needed to evaluate its effectiveness and regional differences. It is important to note that CoMiSS is an awareness tool and not a diagnostic test.
Review
Gastroenterology & Hepatology
Hania Szajewska, Raanan Shamir, Agata Strozyk, Anna Chmielewska, Bartlomiej M. Zalewski, Renata Auricchio, Sibylle Koletzko, Ilma R. Korponay-Szabo, M. Luisa Mearin, Caroline Meijer, Carmen Ribes-Koninckx, Riccardo Troncone
Summary: The effects of early feeding practices on the risk of coeliac disease (CD) remain debated. Breastfeeding and age at gluten introduction have no effect on the cumulative incidence of CD during childhood in the population at genetic risk of CD. There is some evidence that consuming a higher amount of gluten at weaning and/or thereafter may increase CD/CDA risk.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Review
Nutrition & Dietetics
Flavia Indrio, Vanessa Nadia Dargenio, Ruggiero Francavilla, Hania Szajewska, Yvan Vandenplas
Summary: About 25% of infants experience prolonged crying or colic during the first three months of life, and there is limited understanding of its long-term consequences. Literature suggests an association between infant colic and the development of gastrointestinal disorders, headaches, and behavioral problems later in life. However, the current evidence is based on correlations, and a causal relationship has not been established.
Review
Nutrition & Dietetics
Mateusz Jankiewicz, Linde van Lee, Mirthe Biesheuvel, Elske M. Brouwer-Brolsma, Lucie van der Zee, Hania Szajewska
Summary: A systematic evaluation of goat-milk-based infant formulas (GMFs) compared to cow-milk-based formulas (CMFs) found no significant differences in infant growth and safety parameters. Although there were some concerns and biases in the included studies, the results provide reassurance that GMFs are similarly safe and well tolerated as CMFs for infants.
Review
Endocrinology & Metabolism
Bernadeta Patro-Golab, Bartlomiej M. Zalewski, Michael Kammermeier, Lukas Schwingshackl, Berthold Koletzko
Summary: This study systematically evaluated the association between dietary fat intake during pregnancy and childhood and health outcomes. The results showed that omega-3 fatty acids supplementation during pregnancy reduces the risk of preterm birth and improves gestation length and birth weight. However, the intake of polyunsaturated fatty acids (PUFA) during infancy and childhood did not consistently show associations with various health outcomes. Reducing saturated fatty acids (SFA) intake and replacing it with PUFA/monounsaturated fatty acids had favorable effects on blood pressure and blood lipids in children. Further research is needed to better understand the role of omega-3 PUFA supplementation during pregnancy and the reduction of SFA intake in childhood in dietary recommendations.
ANNALS OF NUTRITION AND METABOLISM
(2023)