Journal
SOFT MATTER
Volume 7, Issue 11, Pages 5194-5199Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0sm01529f
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Funding
- Xunta de Galicia [10PXIB206258PR]
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In the current work we proposed the new idea of self-assembled drug based on the combination of two or more drugs. As model system we used hexadecyldimethylammonium bromide: dicloxacilin at room temperature. The two drugs are well known for their therapeutic effect and together form wormlike micelles with the combined therapeutic effect of both individual compounds. The system was investigated using, density and sound velocity, dynamic light scattering and cryo-electron microscopy (cryo-TEM) and UV for a complete physicochemical and stability characterization.
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