Article
Chemistry, Multidisciplinary
Casper Kunstmann-Olsen, Domagoj Belic, Dan F. Bradley, Stephen P. Danks, Yuri A. Diaz Fernandez, Marcin P. Grzelczak, Alexander P. Hill, Xiaohang Qiao, Rasmita Raval, Ioritz Sorzabal-Bellido, Mathias Brust
Summary: The experiment demonstrates the selective unidirectional transport of barium ions between water-in-chloroform emulsion droplets using gold nanoparticles modified with thiolated crown ether. The shuttle action of the gold nanoparticles is potentially influenced by the charging of the metal cores and the electrostatically coupled secondary processes that maintain the electroneutrality of the emulsion droplets.Various techniques including optical microscopy, Raman spectroscopy, cryo-SEM, and zeta potential were used to monitor and study the processes involved.
NANOSCALE ADVANCES
(2021)
Article
Chemistry, Multidisciplinary
Nicolai N. Bach, Verena Josef, Harald Maid, Henry Dube
Summary: Researchers have developed a macrocyclic molecular motor structure that can convert a flexible chain into unidirectional linear motion through active mechanical threading. This offers a new approach for molecular knitting technology.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Physics, Multidisciplinary
Xin Shi, Anna-Katharina Pumm, Jonas Isensee, Wenxuan Zhao, Daniel Verschueren, Alejandro Martin-Gonzalez, Ramin Golestanian, Hendrik Dietz, Cees Dekker
Summary: Researchers have demonstrated a self-assembled DNA nanostructure that exhibits flow-driven rotary motion when docked onto a nanopore. These artificial nanoengines operate autonomously under physiological conditions, providing a new approach to constructing energy-transducing motors at nanoscale interfaces.
Article
Chemistry, Physical
T. Bhatia
Summary: Experimental results show that when in contact with excess water, the lamellae composed of DOPC form multilamellar structures at the interface between pure solvent and lipid, evolving slowly through flow and coalescence without a unique kinetic pathway. Tubular structures disintegrate slowly into the bulk water phase inside a sealed chamber.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Multidisciplinary Sciences
D. Cruz-Zarate, O. Lopez-Ortega, D. A. Giron-Perez, A. M. Gonzalez-Suarez, J. L. Garcia-Cordero, M. Schnoor, L. Santos-Argumedo
Summary: Myosin-1g deficiency affects the migration of B lymphocytes, reducing their ability to enter lymph nodes. Lack of Myo1g causes adhesion and chemotaxis defects, as well as flaws in adopting a migratory morphology.
SCIENTIFIC REPORTS
(2021)
Review
Biochemistry & Molecular Biology
Kenshiro Fujise, Satoru Noguchi, Tetsuya Takeda
Summary: This review provides an overview of the functions of dynamin 2 and BIN1 in T-tubule biogenesis and discusses how their dysfunction in membrane remodelling leads to CNM pathogenesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Broderick L. Bills, Michelle K. Knowles
Summary: Phosphatidic acid (PA), a signaling lipid with a negative charge and small headgroup, is capable of localizing to regions of negative curvature and supporting the formation of curved, tubulated membranes.
Article
Nanoscience & Nanotechnology
Dean Thomas, Daniel J. Tetlow, Yansong Ren, Salma Kassem, Ulvi Karaca, David A. Leigh
Summary: The sorption of species from a solution into and onto solids plays a crucial role in various technologies. This study introduces a molecular pump system immobilized on polymer beads that uses an energy ratchet mechanism to directionally transport substrates from solution onto the beads. This non-equilibrium sorption enables the transduction of energy from chemical fuels for energy and information utilization, storage, and release.
NATURE NANOTECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Stefano Corra, Marina Tranfic Bakic, Jessica Groppi, Massimo Baroncini, Serena Silvi, Emanuele Penocchio, Massimiliano Esposito, Alberto Credi
Summary: This study presents a theoretical model and experimental evidence for the operation of an out-of-equilibrium photoactivated artificial molecular pump. The relationship between light energy input and the deviation of the dissipative state from thermodynamic equilibrium in this artificial system is quantitatively analyzed.
NATURE NANOTECHNOLOGY
(2022)
Article
Physics, Fluids & Plasmas
Thomas Speck
Summary: This study investigates microscopic engines that utilize a single active particle as the working medium, demonstrating the recovery of energy for work during the directed motion of the particle at constant temperature. By considering the chemical degrees of freedom, a wide range of synthetic active particles can be studied without the need to determine the exact microscopic mechanism. Analytical results reveal that the quasistatic thermodynamic efficiency increases beyond the linear-response regime and reaches a maximum at high propulsion speeds, indicating the nontrivial consequences of driving in the active engine's efficiency.
Review
Biochemistry & Molecular Biology
Mitali Shah, Leeba Ann Chacko, Joel P. Joseph, Vaishnavi Ananthanarayanan
Summary: The ability of mitochondria to undergo fission and fusion, and to be transported and anchored within a cell relies heavily on the cytoskeletal filaments, particularly microtubules, F-actin, and intermediate filaments. The dynamic relationship between the cytoskeleton and mitochondria shapes the form and position of the mitochondria, ultimately influencing the functioning of the cell.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2021)
Article
Chemistry, Physical
Mykola Tasinkevych, Artem Ryabov
Summary: We studied the dynamics of a chemical nanoswimmer in a periodically rocked ratchet potential, and found that mechanochemical coupling can be utilized to control the motion of chemically active particles at the nanoscale.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Multidisciplinary
Sofie K. Jensen, Mathias S. Neumann, Rikke Frederiksen, Mathias L. Skavenborg, Mads C. Larsen, Stinne E. Wessel, Jan O. Jeppesen
Summary: Controlling the movement of CBPQT(4+) ring is essential for the full potential utilization of artificial molecular machines. In this study, two isomeric tri-stable [2]rotaxanes incorporating TTF and MPTTF units were synthesized to measure the energy barriers during the movement of CBPQT(4+) ring. By strategically exchanging thiomethyl barriers with thioethyl groups, the movement of CBPQT(4+) ring in the synthesized compounds can be controlled to occur in only one direction. Cyclic voltammetry and H-1 NMR spectroscopy were used to investigate the switching mechanism. The results demonstrate the first successful induction of directional movement of CBPQT(4+) ring in molecular machines using a combination of TTF and MPTTF units with 90% efficiency.
Article
Physics, Multidisciplinary
Xubiao Peng, Jin Dai, Antti J. Niemi
Summary: A deformable body can rotate without angular momentum simply by changing its shape, as demonstrated in molecular dynamics simulations on an isolated cyclopropane molecule. This phenomenon, which can be observed in triangular molecules, shows self-organization into collective oscillatory motion and has potential applications in sensor and control technologies.
NEW JOURNAL OF PHYSICS
(2021)
Article
Mathematics, Interdisciplinary Applications
Akriti Jindal, Arvind Kumar Gupta
Summary: This study investigates the effects of local irreversible dissociation of particles moving along a bridge lane in biological transport processes, with a focus on how it impacts bidirectional dynamics and spontaneous symmetry-breaking phenomena. Theoretical framework and simulations show that changes in dissociation rates lead to significant modifications in system behavior, resulting in the emergence of new symmetric and asymmetric phases under specific conditions.
CHAOS SOLITONS & FRACTALS
(2021)
Article
Multidisciplinary Sciences
Adan Olguin-Olguin, Anne Aalto, Benoit Maugis, Aleix Boquet-Pujadas, Dennis Hoffmann, Laura Ermlich, Timo Betz, Nir S. Gov, Michal Reichman-Fried, Erez Raz
Summary: In studying the mechanisms controlling front-rear polarity in migrating cells using zebrafish primordial germ cells as an in vivo model, it was found that the accumulation and flow of actin plays a key role. Following cell division, the accumulation of Ezrin at the cleavage plane is the first sign for cell polarity. The antagonistic interactions between the cell front and back determine the polarization of the cell.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Elya Dekel, Dana Yaffe, Irit Rosenhek-Goldian, Gili Ben-Nissan, Yifat Ofir-Birin, Mattia I. Morandi, Tamar Ziv, Xavier Sisquella, Matthew A. Pimentel, Thomas Nebl, Eugene Kapp, Yael Ohana Daniel, Paula Abou Karam, Daniel Alfandari, Ron Rotkopf, Shimrit Malihi, Tal Block Temin, Debakshi Mullick, Or-Yam Revach, Ariel Rudik, Nir S. Gov, Ido Azuri, Ziv Porat, Giulia Bergamaschi, Raya Sorkin, Gijs J. L. Wuite, Ori Avinoam, Teresa G. Carvalho, Sidney R. Cohen, Michal Sharon, Neta Regev-Rudzki
Summary: The study demonstrates that Plasmodium falciparum secretes extracellular vesicles (EVs) containing functional 20S proteasome complexes which remodel the cytoskeleton of naive human red blood cells, preparing them for parasite invasion.
NATURE COMMUNICATIONS
(2021)
Article
Physics, Multidisciplinary
Raj Kumar Sadhu, Samo Penic, Ales Iglic, Nir S. Gov
Summary: The study reveals that a high concentration of curved proteins can increase cell spreading by reducing bending energy penalty, especially in the low bare vesicle-substrate adhesion regime. Curved proteins inducing protrusive forces help cells form sheet-like lamellipodia structures.
EUROPEAN PHYSICAL JOURNAL PLUS
(2021)
Article
Biochemistry & Molecular Biology
Harikrishnan Rajendran, Amir Haluts, Nir S. Gov, Ofer Feinerman
Summary: Social groups often need to overcome differences in individual interests and knowledge to reach consensus decisions. In the case of emigrating ant colonies, cohesive emigration is achieved only by intermediate-sized colonies, and individuals are willing to concede their potential benefit to promote social consensus.
Article
Multidisciplinary Sciences
Vivek H. Sridhar, Liang Li, Dan Gorbonos, Mate Nagy, Bianca R. Schell, Timothy Sorochkin, Nir S. Gov, Iain D. Couzin
Summary: The study reveals that animals make multichoice decisions by breaking them into a series of binary decisions in space-time, with spontaneous and abrupt critical transitions occurring during the process. This happens across different taxa and ecological contexts, demonstrating fundamental geometric principles underlying animal decision-making.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Amir Haluts, Sylvia F. Garza Reyes, Dan Gorbonos, Robert Ian Etheredge, Alex Jordan, Nir S. Gov
Summary: Competition among animals for resources is common at all levels of life. It is often resolved through contests, where outcomes depend on decision-making by individuals. By studying simple systems, a theoretical framework can be constructed to understand animal contest behaviors.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Correction
Physics, Multidisciplinary
Raj Kumar Sadhu, Samo Penic, Ales Iglic, Nir S. Gov
EUROPEAN PHYSICAL JOURNAL PLUS
(2022)
Article
Multidisciplinary Sciences
Adel Al Jord, Gaelle Letort, Soline Chanet, Feng-Ching Tsai, Christophe Antoniewski, Adrien Eichmuller, Christelle Da Silva, Jean-Rene Huynh, Nir S. Gov, Raphael Voituriez, Marie-Emilie Terret, Marie-Helene Verlhac
Summary: Cells can regulate the function of nuclear condensates through the use of cytoplasmic forces generated by cytoskeletal motors. This finding has implications for understanding and studying diseases associated with nuclear condensates.
NATURE COMMUNICATIONS
(2022)
Article
Physics, Multidisciplinary
Rituparno Mandal, Saroj Kumar Nandi, Chandan Dasgupta, Peter Sollich, Nir S. Gov
Summary: This study simulated the behavior of active glass and found that the activity parameters have an impact on the relaxation time of the structural arrangement. In the case of high activity, the extended model predicts qualitative changes.
JOURNAL OF PHYSICS COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Raj Kumar Sadhu, Sarah R. Barger, Samo Penic, Ales Iglic, Mira Krendel, Nils C. Gauthier, Nir S. Gov
Summary: Phagocytosis is the process of cells engulfing large particles, and the presence of curved proteins and the recruitment of cytoskeletal forces can enhance this process. Our model provides a mechanism for the self-organization of the actin cytoskeleton at the phagocytic cup, leading to faster engulfment.
Article
Chemistry, Multidisciplinary
Apratim Mukherjee, Jonathan Emanuel Ron, Hooi Ting Hu, Tamako Nishimura, Kyoko Hanawa-Suetsugu, Bahareh Behkam, Yuko Mimori-Kiyosue, Nir Shachna Gov, Shiro Suetsugu, Amrinder Singh Nain
Summary: This study investigates the role of IRSp53 as a regulator of membrane curvature during cell migration on single, suspended 1D fibers. IRSp53 depletion reduces actin stress fibers, protrusive activity, and contractility, leading to uncoupling of the nucleus from cellular movements. The findings demonstrate the unique role of IRSp53 in controlling cell migration in 3D.
Review
Developmental Biology
Lior Atia, Jeffrey J. Fredberg, Nir S. Gov, Adrian F. Pegoraro
Summary: Recent evidence supports the transition of multicellular tissue from a jammed phase to an unjammed phase, impacting tissue homeostasis and developmental dynamics. The gradual departure from a jammed phase may enable controlled malleability required in development.
CELLS & DEVELOPMENT
(2021)
Article
Mathematics, Interdisciplinary Applications
Oran Ayalon, Yigal Sternklar, Ehud Fonio, Amos Korman, Nir S. Gov, Ofer Feinerman
Summary: Cooperative transport of large food loads by Paratrechina longicornis ants involves repeated decision-making processes, with carried loads exhibiting biased random walk behavior. This behavior reflects an emergent version of the psychophysical Weber's law. The variable step size of the carried loads expands the scope of the Evidence Accumulation model from isolated to sequential decisions.
FRONTIERS IN APPLIED MATHEMATICS AND STATISTICS
(2021)
Article
Biophysics
Inge M. N. Wortel, Ioana Niculescu, P. Martijn Kolijn, Nir S. Gov, Rob J. de Boer, Johannes Textor
Summary: Cell migration is diverse, but a universal coupling between speed and persistence exists. An existing cellular Potts model shows how cell shape dynamics and local protrusion dynamics play a role in reproducing this speed-persistence coupling.
BIOPHYSICAL JOURNAL
(2021)
Article
Physics, Fluids & Plasmas
Arik Yochelis, Carsten Beta, Nir S. Gov
Article
Chemistry, Physical
Yiping Yin, Zhe Wang, Hua Zou
Summary: This study presents a novel method for preparing dimpled polymer-silica nanocomposite particles using interfacial swelling-based seeded polymerization. The optimized conditions allow for a relatively high percentage of dimpled particles to be achieved.
Article
Chemistry, Physical
Brenden D. Hoehn, Elizabeth A. Kellstedt, Marc A. Hillmyer
Summary: Porous materials with nanometer-scale pores have important applications as nanoporous membranes. In this study, ABA triblock copolymers were used as precursors to produce nanoporous polymeric membranes (NPMs) in thin film form by degrading the end blocks. Polycyclooctene (PCOE) NPMs with tunable pore sizes were successfully prepared using solvent casting technique. Oxygen plasma etching was employed to improve the surface porosity and hydrophilicity of the membranes. This study provides a straightforward method to produce tough NPMs with high porosity and hydrophilic surface properties.
Article
Chemistry, Physical
Vladislav S. Petrovskii, Stepan I. Zholudev, Igor I. Potemkin
Summary: This article investigates the behavior of linear and ring polypeptide chains in aqueous solution and explores the properties of the complexes formed by these chains with oppositely charged surfactants. The results demonstrate that the complexes of linear supercharged unfolded polypeptides and the corresponding surfactants exhibit impressive adhesive properties.
Article
Chemistry, Physical
Merve Cevik, Serkan Dikici
Summary: Cardiovascular diseases are a leading cause of death globally, and vascular grafts are a promising treatment option. This study focuses on tissue-engineered vascular grafts (TEVGs) using decellularized parsley stems as a potential biomaterial. The decellularized parsley stems showed suitable properties for TEVGs, providing a suitable environment for human endothelial cells to form a pseudo endothelium. This study showcases the potential of using parsley stems for TEVGs.
Article
Chemistry, Physical
Gustavo A. Vasquez-Montoya, Tadej Emersic, Noe Atzin, Antonio Tavera-Vazquez, Ali Mozaffari, Rui Zhang, Orlando Guzman, Alexey Snezhko, Paul F. Nealey, Juan J. de Pablo
Summary: The optical properties of liquid crystals are typically controlled by electric fields. In this study, we investigate the effects of microfluidic flows and acoustic fields on the molecular orientation and optical response of nematic liquid crystals. We identify several previously unknown structures and explain them through calculations and simulations. These findings hold promise for the development of new systems combining sound, flow, and confinement.
Article
Chemistry, Physical
Xinjun Wu, Xin Guan, Shushu Chen, Jiangpeng Jia, Chongyi Chen, Jiawei Zhang, Chuanzhuang Zhao
Summary: This research presents a novel shape memory hydrogel with a remodelable permanent shape and programmable cold-induced shape recovery behavior. The hydrogel is prepared using specific treatment methods to achieve shape fixation by heating and shape recovery by cooling. Additionally, deformable devices can be obtained by assembling hydrogel blocks with different concentrations.
Article
Chemistry, Physical
Rebecca Hengsbach, Gerhard Fink, Ulrich Simon
Summary: This study examines the properties of DNA functionalized pNipmam microgels and pure pNipmam microgels at different concentrations of sodium chloride and in PBS solutions using temperature dependent H-1-NMR measurements. The results show that DNA modification affects the volume phase transition temperature and the addition of salt and PBS further enhances this effect.
Article
Chemistry, Physical
Ningyi Li, Junhong Li, Lijingting Qing, Shicheng Ma, Yao Li, Baohui Li
Summary: This paper investigates the self-assembly behavior of colloids with competing interactions under spherical confinement and finds that different ordered structures can be formed under different sized spherical confinements. Moreover, more perforated structures are formed in smaller spheres.
