Article
Obstetrics & Gynecology
Peter G. Middleton
Summary: This review provides a summary of the interactions between pregnancy and breathing during sleep, and highlights the changes in respiratory function that can increase the incidence and severity of sleep-disordered breathing. The increased risk of snoring and obstructive sleep apnea hypopnea syndrome during pregnancy is discussed, and the potential impact of increasing obesity rates on sleep-disordered breathing in pregnant women is considered.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2022)
Review
Clinical Neurology
Zhengfei Huang, Ghizlane Aarab, Madeline J. L. Ravesloot, Ning Zhou, Pien F. N. Bosschieter, Maurits K. A. van Selms, Chantal den Haan, Nico de Vries, Frank Lobbezoo, Antonius A. J. Hilgevoord
Summary: Studies have shown that characteristic frequency components generated from lower-level obstructions of the upper airway were higher than those from upper-level obstructions. Prediction models were mainly built based on snoring sound parameters in the frequency domain, with reported accuracies ranging from 60.4% to 92.2%.
Article
Pediatrics
Saara Markkanen, Markus Rautiainen, Sari-Leena Himanen, Anna-Liisa Satomaa, Maija Katila, Timo Peltomaki, Outi Saarenpaa-Heikkila
Summary: The study identified that in two-year-old children, those with OSA had longer snoring time, a greater tendency for mouth breathing, and larger adenoid size compared to snorers without OSA.
Article
Anesthesiology
Mon Ohn, David Sommerfield, Julie Nguyen, Daisy Evans, R. Nazim Khan, Neil Hauser, Hayley Herbert, Paul Bumbak, Andrew C. Wilson, Peter R. Eastwood, Kathleen J. Maddison, Jennifer H. Walsh, Britta S. von Ungern-Sternberg
Summary: This study investigated the utility of pharyngeal closing pressure (PCLOSE) for predicting obstructive sleep apnoea (OSA) and perioperative respiratory adverse events. The results showed that PCLOSE can reliably identify moderate or severe OSA, but cannot predict perioperative respiratory adverse events.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Review
Medicine, General & Internal
Ming-Shao Tsai, Hung-Chin Chen, Stanley Yung-Chuan Liu, Li-Ang Lee, Cheng-Yu Lin, Geng-He Chang, Yao-Te Tsai, Yi-Chan Lee, Cheng-Ming Hsu, Hsueh-Yu Li
Summary: Obstructive sleep apnea (OSA) is a disease characterized by partial or complete blockage of the airway during sleep. Nasal surgery plays a vital role in the treatment of OSA, as it not only alleviates nasal congestion but also significantly reduces snoring and daytime sleepiness, improving the quality of life for patients. Combining nasal surgery with other surgical methods may lead to better treatment outcomes.
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
(2022)
Article
Chemistry, Multidisciplinary
Bartosz Dalewski, Agata Kaminska, Aleksandra Syrico, Alicja Kaldunska, Lukasz Palka, Ewa Sobolewska
Summary: Snoring patients showed higher BMI, heart rate, modified Mallampati score, and lower UAV compared to non-snoring patients. The modified Mallampati score was identified as a useful indicator of snoring risk.
APPLIED SCIENCES-BASEL
(2021)
Article
Pediatrics
Eduardo Machado Rossi-Monteiro, Laura Rodrigues Sefair, Marcos Correia Lima, Maria Fernanda Lima Nascimento, Daniel Mendes-Pinto, Lukas Anschuetz, Maria Gloria Rodrigues-Machado
Summary: This study aimed to compare cardiovascular parameters between healthy children and those with obstructive sleep-disordered breathing (oSDB), as well as identify predictors of arterial stiffness indices in children with oSDB. Children with oSDB showed higher reflection coefficient and augmentation index compared to controls, indicating increased arterial stiffness. Multiple regression analysis revealed age, female sex, reflection coefficient, and systolic volume as independent predictors of augmentation index, while higher pulse wave velocity was associated with poorer quality of life.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Review
Clinical Neurology
Micheline M. D. De Meyer, Olivier M. Vanderveken, Sonia De Weerdt, Luc A. M. Marks, Bernadita A. Carcamo, Andres M. Chavez, Felipe A. Matamoros, Wolfgang Jacquet
Summary: Mandibular advancement devices showed positive effects in treating snoring, with improvements in symptoms of obstructive sleep apnea syndrome and sleep breathing disorders. Common side effects include temporomandibular joint pain and excessive salivation, which improved over time. Research findings support the use of mandibular advancement devices in treating primary snoring.
SLEEP MEDICINE REVIEWS
(2021)
Article
Respiratory System
Ludovico Messineo, Luigi Taranto-Montemurro, Nicole Calianese, Laura K. Gell, Ali Azarbarzin, Gonzalo Labarca, Dan Vena, Hyung Chae Yang, Tsai-Yu Wang, Andrew Wellman, Scott A. Sands
Summary: While ineffective in unselected patients, Ato-Feso administered for one night suppressed OSA in patients with milder collapsibility. Ato-Feso may hold some promise as an alternative OSA treatment in certain subgroups of individuals.
Review
Biochemistry & Molecular Biology
Maria Carmina Pau, Arduino Aleksander Mangoni, Elisabetta Zinellu, Gianfranco Pintus, Ciriaco Carru, Alessandro Giuseppe Fois, Pietro Pirina, Angelo Zinellu
Summary: The study found that whole blood SOD concentrations were significantly lower in patients with obstructive sleep apnoea, while serum/plasma SOD concentrations did not show a significant difference. This suggests an impaired antioxidant defence in OSA patients.
Article
Neurosciences
Pasquale Tondo, Francesco Fanfulla, Giulia Scioscia, Roberto Sabato, Michela Salvemini, Cosimo C. De Pace, Maria Pia Foschino Barbaro, Donato Lacedonia
Summary: This study found that in young, non-obese individuals, severe obstructive sleep apnoea (OSA) is associated with an increased risk of developing hypertension and nocturnal hypoxemia.
Article
Respiratory System
Jean-Benoit Martinot, Nhat-Nam Le-Dong, Atul Malhotra, Jean-Louis Pepin
Summary: Respiratory effort is a main feature of obstructive sleep apnoea (OSA), and is associated with sympathetic overactivity. This study found that the percentage of total sleep time spent with increased respiratory effort (REMOV,%TST), measured by mandibular jaw movements, can predict the prevalence of hypertension in adults with OSA.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Clinical Neurology
Gurpreet Chaggar, Kate Sutherland, Fang Han, Ingo Fietze, Thomas Penzel, Bryndis Benediktsdottir, Thorarinn Gislason, Ulysses Magalang, Allan Pack, Bhajan Singh, Nigel McArdle, Lia Bittencourt, Qing Yun Li, Ning Hung Chen, Philip de Chazal, Peter A. Cistulli, Yu Sun Bin
Summary: The study found that women who snore during pregnancy continue snoring in later life but do not appear more likely to develop OSA. The findings are limited by self-reported data and a small number of women who reported snoring during pregnancy.
Article
Dentistry, Oral Surgery & Medicine
Nikolaos Ferlias, Hans Gjorup, Mia Aagaard Doherty, Annette Haagerup, Thomas Klit Pedersen
Summary: This study assessed the upper airway morphology in patients with pycnodysostosis using 3D analysis and compared the results with a control group. The findings showed that patients with pycnodysostosis have a smaller total airway and nasopharyngeal volume, as well as reduced cross-sectional areas in the upper and lower borders of the airway. These factors may contribute to the high prevalence of obstructive sleep apnea in pycnodysostosis patients.
ORTHODONTICS & CRANIOFACIAL RESEARCH
(2022)
Article
Nursing
Chestharid Borriboon, Jindarat Chaiard, Chiraporn Tachaudomdach, Sue Turale
Summary: This study aimed to investigate the relationship between health belief model factors and CPAP adherence in Thai individuals with obstructive sleep apnoea. Results showed a low rate of CPAP adherence, with perceived seriousness of the conditions being the only significant factor associated with adherence. Healthcare professionals, especially nurses, should provide support and education to encourage regular CPAP use and be aware of psychological factors affecting patients' perception of sleep apnoea and CPAP treatment. Intervention strategies targeting these factors should be developed and implemented in clinical practice.
JOURNAL OF CLINICAL NURSING
(2022)
Article
Health Care Sciences & Services
Janet A. Wilson, Deborah D. Stocken, Gillian C. Watson, Tony Fouweather, Julian McGlashan, Kenneth MacKenzie, Paul Carding, Yakubu Karagama, Meredydd Harries, Stephen Ball, Sadie Khwaja, Declan Costello, Ruth Wood, Jan Lecouturier, James O'Hara
Summary: This study evaluated the value of proton pump inhibitor therapy in patients with persistent throat symptoms through a randomized controlled trial. The results showed that participants on lansoprazole did not report significantly better outcomes than those on placebo after 16 weeks of treatment.
HEALTH TECHNOLOGY ASSESSMENT
(2021)
Article
Otorhinolaryngology
Daniel J. Lin, Jenan Altamimi, Kim Pearce, Janet A. Wilson, Joanne M. Patterson
Summary: The study evaluated the structure of the MDADI questionnaire and identified overlapping items between emotional, functional, and physical subscales. It suggests abbreviating the MDADI questionnaire to a 5-item MiniDADI questionnaire for potentially greater utility in routine clinical practice.
Article
Otorhinolaryngology
H. Mohammed, M. W. Mather, J. Lumb, C. C. Butler, J. A. Wilson
Summary: General practitioners frequently prescribe oral antibiotics for otitis externa, leading to a 25% increase in consultations over 15 years. Antimicrobial drug resistance is common in otitis externa, and there are systematic inconsistencies in available guidelines.
JOURNAL OF LARYNGOLOGY AND OTOLOGY
(2022)
Article
Otorhinolaryngology
C. Haighton, R. M. Watson, J. A. Wilson, S. Powell
Summary: This study explored treatment pathways and well-being factors for parents and children with pediatric sleep-disordered breathing in the UK. It found that general practitioners often do not identify these issues, while hospital doctors do. Parents are concerned about their child's breathing, but the referral and diagnosis process is not straightforward.
JOURNAL OF LARYNGOLOGY AND OTOLOGY
(2022)
Article
Surgery
Michael W. Mather, Janet A. Wilson, Mary Doona, Benjamin J. Talks, Mark Fullard, Michael Griffin, Jason Powell, Michael Drinnan
Summary: This study developed a predictive model for oesophageal malignancy based on a questionnaire survey and data analysis, identifying symptoms associated with the risk of oesophageal cancer. The model provides valuable insights for future research on predicting oesophageal malignancy in the general population.
SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND
(2023)
Article
Gastroenterology & Hepatology
James O'Hara, Holly Fisher, Louise Hayes, Janet Wilson
Summary: This study explores the patterns of chronic symptoms in patients with throat disorders and aims to provide a rational basis for treatment. The analysis of baseline data reveals that throat clearing and globus are the most common symptoms, and symptom severity decreases with increasing age. Exploratory factor analysis identifies seven clinically meaningful symptom factors. However, cluster analysis fails to identify distinct groups of patients. Individual symptoms cannot be used to group patients, and a broad term like persistent throat symptoms is more appropriate.
BMJ OPEN GASTROENTEROLOGY
(2022)
Article
Medicine, General & Internal
David Winston Hamilton, Benjamin Heaven, Richard Thomson, Janet Wilson, Catherine Exley
Summary: This study describes how patients are engaged in cancer decisions within the context of multidisciplinary teams (MDTs) and how MDT recommendations are implemented in shared decision-making. The current MDT decision-making model does not support shared decision-making and may even undermine it. The study suggests the need for a new MDT working model that incorporates the individual patient perspective and allows for discussion of potential treatment options.
Article
Neurosciences
Rachel L. Sharman, Celyne H. Bastien, Michael L. Perlis, Mark A. Wetherell, Nicola L. Barclay, Nayantara Santhi, Jason G. Ellis, Greg J. Elder
Summary: This study found that in healthy normal sleepers, unexpected exposure to ecologically valid common nocturnal noises during non-rapid eye movement (NREM) sleep did not significantly affect the discrepancy between subjective and objective sleep time.
Article
Health Care Sciences & Services
Michael Nugent, Valerie Bryant, Chrissie Butcher, Holly Fisher, Sean Gill, Rebecca Goranova, Shaun Hiu, Lyndsay Lindley, James O'Hara, Yemi Oluboyede, Joanne Patterson, Tim Rapley, Tomos Robinson, Nikki Rousseau, Vicky Ryan, Ramkumar Shanmugasundaram, Linda Sharp, Ruby Smith Whelan, Deborah D. Stocken, Laura Ternent, Janet Wilson, Jenn Walker
Summary: This study aimed to assess the clinical effectiveness and cost-effectiveness of low-level laser therapy in the management of oral mucositis in head and neck cancer irradiation and to identify barriers and facilitators of implementing the therapy. The results of the trial showed that low-level laser therapy did not significantly outperform other methods in relieving oral mucositis. However, the therapy is relatively inexpensive and clinicians more easily adapt to delivering it.
HEALTH TECHNOLOGY ASSESSMENT
(2022)
Review
Clinical Neurology
Umair Akram, Nicola Barclay, Bronwyn Milkins, Jodie Stevenson, Maria Gardani
Summary: Cognitive models of insomnia suggest that cognitive biases towards sleep-related threat play a role in maintaining the disorder. This systematic review includes meta-analytic calculations of attentional and interpretive biases in sleep. The results indicate that congruent cognitive biases are a key feature of insomnia, but the lack of longitudinal data limits causal inference. Methodological factors are discussed in relation to outcome variation, and future steps in understanding sleep-related biases in insomnia are proposed.
SLEEP MEDICINE REVIEWS
(2023)
Article
Medicine, General & Internal
Cara Mooney, David Alexander White, Jeremy Dawson, Vincent Deary, Kate Fryer, Monica Greco, Michelle Horspool, Aileen Neilson, Gillian Rowlands, Tom Sanders, Ruth E. Thomas, Steve Thomas, Waquas Waheed, Christopher D. Burton
Summary: This pragmatic, multicentre, randomised controlled trial aims to evaluate the clinical and cost-effectiveness of the symptoms clinic intervention plus usual care compared with usual care alone. A total of 354 participants were recruited and individually randomised (1:1). The primary outcome is the self-reported Physical Health Questionnaire-15 at 52 weeks postrandomisation. Secondary outcome measures include the EuroQol 5 dimension 5 level and healthcare resource use. A process evaluation will also be conducted, including consultation content analysis and interviews with participants and key stakeholders.
Article
Multidisciplinary Sciences
Jemma L. McCready, Kristofor McCarty, Vincent Deary, Tracy L. Collins, Katie L. Hackett
Summary: This qualitative study explores the conversations about female sexual function and the sexual environment among individuals with Sjogren's syndrome (SS) on an internet forum. The findings identify the impact of SS symptoms on the sexual environment, the emotional responses to sexual difficulties, the strategies used to manage sexual problems, and the influence of a partner's behavior. These insights provide valuable information for clinical discussions and emphasize the importance of qualitative research with this population.
Article
Otorhinolaryngology
Catherine Haighton, Rose Mary Watson, Janet A. Wilson, Steven Powell
CLINICAL OTOLARYNGOLOGY
(2023)
Article
Primary Health Care
Michael W. Mather, Hassan Mohammed, Janet A. Wilson
Summary: Referrals for otitis externa (OE) have significantly increased, but the reasons for this remain unclear. A study found that patients often consult primary care several times before referral. Additionally, many patients do not follow the recommended use of appropriate ear drops and are instead treated with oral antibiotics. This highlights the need for improvement at the primary-secondary care interface.
Article
Clinical Neurology
Rachel L. Sharman, Michael L. Perlis, Celyne H. Bastien, Nicola L. Barclay, Jason G. Ellis, Greg J. Elder
Summary: Specific noises can disrupt sleep and cause a mismatch between subjective sleep and objective sleep. Individuals' sensitivity to noise-related sleep disturbances may vary, possibly due to increased pre-sleep cognitive arousal. This study aimed to investigate the relationship between pre-sleep cognitive arousal and sleep misperception.
