Review
Clinical Neurology
Oliver Pearson, Nora Uglik-Marucha, Kamilla W. Miskowiak, Scott A. Cairney, Ivana Rosenzweig, Allan H. Young, Paul R. A. Stokes
Summary: This systematic review examined the relationship between sleep disturbance and cognitive impairment in mood disorders. The findings indicate a significant association between sleep disturbance and cognitive impairment in people with mood disorders after adjusting for demographic and clinical factors, while no such association was found in healthy participants. These results underscore the need for further research on sleep disturbances and cognitive impairment in people with mood disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Yuqi S. Wang, Abbey L. Friedman, Karen P. Jakubowski, Delainey L. Wescott, Praise Iyiewuare, Julia S. Feldman, Daniel S. Shaw, Kathryn A. Roecklein
Summary: This study investigated the role of childhood maltreatment in Seasonal Affective Disorder (SAD) and found that insomnia, ruminative brooding, and seasonal maladaptive beliefs may account for the association between childhood maltreatment and SAD symptom severity.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychology, Clinical
Delainey L. Wescott, Peter L. Franzen, Brant P. Hasler, Megan A. Miller, Adriane M. Soehner, Stephen F. Smagula, Meredith L. Wallace, Martica H. Hall, Kathryn A. Roecklein
Summary: This study aims to clarify the nature and extent of hypersomnolence in seasonal affective disorder (SAD) using multiple measurements. The results suggest that hypersomnolence is not a poor characterization of SAD, and self-reported hypersomnia captures multiple sleep disruptions.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Clinical Neurology
Hu Deng, Fang Wen, Hui Xu, Hanxue Yang, Junjuan Yan, Yi Zheng, Yonghua Cui, Ying Li
Summary: This study is the first nationwide survey on the prevalence of affective disorders among school-attending children and adolescents aged 6-16 in China. The results showed that the total prevalence of affective disorders was 3.212%, with higher rates among females than males and among adolescents compared to children.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Daniel J. Oakes, Holly A. Pearce, Cerian Roberts, Phillip G. Gehrman, Catrin Lewis, Ian Jones, Katie J. S. Lewis
Summary: This study investigated the association between comorbid anxiety disorder and sleep disturbance in individuals with bipolar disorder. The results showed that comorbid anxiety was associated with subjective sleep disturbance, but not with objective sleep metrics.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Daniel P. Moriarity, Corinne P. Bart, Allison Stumper, Payton Jones, Lauren B. Alloy
Summary: The study found that impulsive and interpersonal impairment were highly comorbid with mood symptoms, while suicidal ideation, sadness, decreased need for sleep, and guilt were most related to substance-related impairment. The components of these syndromes that confer cross-construct risk might not be the same as predicted by the other construct.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Marie Kim Wium-Andersen, Ida Kim Wium-Andersen, Terese Sara Hoj Jorgensen, Martin Balslev Jorgensen, Merete Osler
Summary: Patients with affective disorder have higher absolute and relative risks of most somatic diseases, except for cancers. The strongest associations were found for dementia, hip fracture, COPD, and stroke on both the relative and absolute scale. Further research on shared mechanisms could lead to targeted interventions to reduce the risk.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Kimie Stefanie Ormstrup Sletved, Niels Henrik Falck Villemoes, Klara Coello, Sharleny Stanislaus, Hanne Lie Kjaerstad, Maria Faurholt-Jepsen, Kamilla Miskowiak, Jens Drachmann Bukh, Maj Vinberg, Lars Vedel Kessing
Summary: This study investigated the prevalence of comorbid personality disorders in patients with newly diagnosed BD and their unaffected first-degree relatives compared with healthy control individuals. The results showed that 25.5% of patients with newly diagnosed BD and 6.4% of their relatives fulfilled the criteria for comorbid personality disorders. Subthreshold personality disorders were also more prevalent in BD patients and their relatives. Comorbid personality disorders were associated with impaired functioning in BD patients.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Multidisciplinary
Elena M. D. Schoenthaler, Nina Dalkner, Dirk von Lewinski, Eva Z. Reininghaus, Andreas Baranyi
Summary: The study found that Machiavellianism and psychopathy personality traits are associated with worsened sleep quality. This effect is more pronounced in healthy controls compared to individuals with affective disorders. Therefore, these personality traits should be considered in the prevention and treatment of sleep problems related to affective disorders.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Neurosciences
Kevin S. O'Connell, Oleksandr Frei, Shahram Bahrami, Olav B. Smeland, Francesco Bettella, Weiqiu Cheng, Yunhan Chu, Guy Hindley, Aihua Lin, Alexey Shadrin, Elizabeth Ann Barrett, Trine Vik Lagerberg, Nils Eiel Steen, Anders M. Dale, Srdjan Djurovic, Ole A. Andreassen
Summary: The study reveals extensive genetic overlap between psychiatric disorders and sleep-related phenotypes, with moderate levels of congruence. Specific shared loci have been identified and mapped to 70 credible genes. These findings offer new opportunities for future research.
BIOLOGICAL PSYCHIATRY
(2021)
Article
Clinical Neurology
Stine Holmstul Glastad, Sofie Ragnhild Aminoff, Roger Hagen, Margrethe Collier Hoegh, Camilla Bakkalia Buchmann, Elizabeth Ann Barrett, Ingrid Melle, Bruno Etain, Trine Vik Lagerberg
Summary: This study aimed to investigate the relationship between nicotine use, non-pathological alcohol use, affective symptoms, and sleep disturbances in individuals with bipolar disorder. The results showed that individuals with medium and high levels of daily nicotine use had a higher risk of insomnia. Non-pathological alcohol use was not associated with sleep disturbances.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Multidisciplinary Sciences
Aditya Ambati, Ryan Hillary, Smaranda Leu-Semenescu, Hanna M. Ollila, Ling Lin, Emmanuel H. During, Neal Farber, Thomas J. Rico, Juliette Faraco, Eileen Leary, Andrea N. Goldstein-Piekarski, Yu-Shu Huang, Fang Han, Yakov Sivan, Michel Lecendreux, Pauline Dodet, Makoto Honda, Natan Gadoth, Sona Nevsimalova, Fabio Pizza, Takashi Kanbayashi, Rosa Peraita-Adrados, Guy D. Leschziner, Rosa Hasan, Francesca Canellas, Kazuhiko Kume, Makrina Daniilidou, Patrice Bourgin, David Rye, Jose L. Vicario, Birgit Hogl, Seung Chul Hong, Guiseppe Plazzi, Geert Mayer, Anne Marie Landtblom, Yves Dauvilliers, Isabelle Arnulf, Emmanuel Jean-Marie Mignot
Summary: KLS is a rare disorder characterized by severe episodic hypersomnia, with possible genetic and obstetrical risk factors. A genome-wide study identified a significant association with TRANK1 gene and reported birth difficulties in KLS cases. Genetic liability and pathway analysis suggest links between KLS, circadian regulation, and bipolar disorder.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Clinical Neurology
Raphael O. Cerqueira, Carolina Ziebold, Daniel Cavalcante, Giovany Oliveira, Javiera Vasquez, Juan Undurraga, Alfonso Gonzalez-Valderrama, Ruben Nachar, Carlos Lopez-Jaramillo, Cristiano Noto, Nicolas Crossley, Ary Gadelha
Summary: This study compares patients with affective and non-affective psychosis (A-FEP and NA-FEP) in a Latin American sample. The findings suggest that characteristics of FEP patients could be utilized to enhance diagnosis and inform treatment decisions.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Clinical
Mark Zimmerman, Caroline Balling, Iwona Chelminski, Kristy Dalrymple
Summary: Patients with both bipolar disorder and BPD exhibit more severe psychosocial morbidity compared to those with only one of these disorders.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Psychiatry
Leonid Braverman, Camil Fuchs, Abraham Weizman, Michael Poyurovsky
Summary: Evidence suggests a higher comorbidity rate of obsessive-compulsive disorder (OCD) in bipolar disorder (BD) patients, particularly in those experiencing bipolar depression (BP-D). A study found 26% of BD patients with their first depressive episode also had OCD, while 23.2% met criteria for subthreshold OCD. No differences in demographic and clinical variables were observed between BD patients with and without OCD. Further research is needed to explore the longitudinal course, treatment approaches, and outcomes of comorbid BP-D/OCD.
PSYCHIATRY RESEARCH
(2021)