Article
Environmental Studies
Wessel M. A. van Leeuwen, Claire Pekcan, Mike Barnett, Goran Kecklund
Summary: Ships operate 24/7, with various working time arrangements. A study compared 2-watch and 3-watch systems in terms of sleepiness and sleep duration predictions, finding that individual differences in chronotype impact the effectiveness of scheduling. 3-watch systems have advantages over 2-watch systems, but individual differences should be considered for optimal scheduling.
Article
Psychology, Social
Joshua Tutek, William K. Wohlgemuth, Kenneth L. Lichstein
Summary: The study investigated whether trait mindfulness predicts daytime impairment caused by poor sleep. Mindfulness was found to have strong negative correlations with nighttime and daytime sleep symptoms.
PERSONALITY AND INDIVIDUAL DIFFERENCES
(2021)
Article
Clinical Neurology
Tomi Sarkanen, Markku Partinen, Bjorn Bjorvatn, Ilona Merikanto, Christian Benedict, Michael R. Nadorff, Courtney J. Bolstad, Colin Espie, Kentaro Matsui, Frances Chung, Charles M. Morin, Yun Kwok Wing, Thomas Penzel, Taina Macedo, Sergio Mota-Rolim, Brigitte Holzinger, Giuseppe Plazzi, Luigi De Gennaro, Anne-Marie Landtblom, Yuichi Inoue, Mariuz Sieminski, Damien Leger, Yves Dauvilliers
Summary: The COVID-19 pandemic and related restriction measures have led to an increase in excessive daytime sleepiness, excessive quantity of sleep, and fatigue. Self-reported cases of COVID-19 are particularly associated with these sleep problems. Shorter sleep duration than desired, depressive symptoms, use of hypnotics, and having reported COVID-19 are strong predictors of excessive daytime sleepiness.
Article
Psychology, Multidisciplinary
Karin Elisabeth Sundt Mjelle, Sverre Lehmann, Ingvild West Saxvig, Shashi Gulati, Bjorn Bjorvatn
Summary: This study investigates the possible associations between obstructive sleep apnea (OSA) and fatigue, as well as the associations with excessive sleepiness, depression, and anxiety. The study finds that pathological fatigue, anxiety, and depression do not increase with the severity of OSA, while excessive sleepiness does.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Clinical Neurology
Shamsi Shekari Soleimanloo, Veronica Garcia-Hansen, Melanie J. White, M. Mamun Huda, Simon S. Smith
Summary: This study found that bright light or caffeine can improve driving performance and subjective sleepiness compared to a placebo. The combination of bright light and caffeine has even greater effects. Bright light could serve as a practical alternative to caffeine for sleepy drivers, helping them stay alert and reducing the risk of severe accidents.
Article
Chemistry, Analytical
Georgia A. Tuckwell, James A. Keal, Charlotte C. Gupta, Sally A. Ferguson, Jarrad D. Kowlessar, Grace E. Vincent
Summary: This study applied deep learning to classify the sitting and sleep history of drivers using thigh-worn accelerometer data collected during a simulated drive. The results showed that the convolutional neural network ResNet-18 achieved higher accuracy in identifying the activity and sleep history of drivers compared to DixonNet. This approach has important implications for identifying drivers at risk of fatigue-related impairment.
Article
Clinical Neurology
Marta Bellofatto, Luca Gentile, Alessandro Bertini, Irene Tramacere, Fiore Manganelli, Gian Maria Fabrizi, Angelo Schenone, Lucio Santoro, Tiziana Cavallaro, Marina Grandis, Stefano Previtali, Marina Scarlato, Isabella Allegri, Luca Padua, Costanza Pazzaglia, Flavio Villani, Eleonora Cavalca, Paola Saveri, Aldo Quattrone, Paola Valentino, Stefano Tozza, Massimo Russo, Anna Mazzeo, Giuseppe Vita, Sylvie Piacentini, Giuseppe Didato, Chiara Pisciotta, Davide Pareyson, CMT Network
Summary: This study investigated the presence of sleep abnormalities in Charcot-Marie-Tooth disease (CMT) patients and their correlation with disease severity and characteristics. The results showed that CMT patients had poor sleep quality and daytime somnolence, which were associated with anxiety, depression, and fatigue.
JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Adam C. Raikes, Natalie S. Dailey, Brittany Forbeck, Anna Alkozei, William D. S. Killgore
Summary: The study showed that daily morning blue light therapy (BLT) can lead to significant increases in gray matter volume and functional connectivity in areas associated with sleep regulation and daytime cognitive function, alertness, and attention. These changes were associated with improvements in self-reported daytime sleepiness.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Bernie Y. Sunwoo, Christopher N. Kaufmann, Andrea Murez, Ellen Lee, Dillon Gilbertson, Naa-Oye Bosompra, Pamela DeYoung, Atul Malhotra
Summary: This study found that the Epworth Sleepiness Scale (ESS) is not able to accurately differentiate patients with or without obstructive sleep apnea (OSA), while the Language of Sleepiness Questionnaire (LOS) can better capture daytime complaints in OSA patients. The use of LOS can help improve the diagnosis and assessment of OSA.
SLEEP AND BREATHING
(2023)
Article
Clinical Neurology
Courtney E. Casale, Erika M. Yamazaki, Tess E. Brieva, Caroline A. Antler, Namni Goel
Summary: This study aimed to compare different methods for defining resilience and vulnerability based on subjective metrics. The results showed that only the Raw Score approach consistently distinguished Resilient and Vulnerable groups, while the other approaches differed in their categorizations. The study suggests using the Raw Score approach as an effective method for subjective resilience/vulnerability categorization.
Review
Neurosciences
Divyani Garg, Laurel Charlesworth, Garima Shukla
Summary: This systematic review aims to describe the association between temporal lobe epilepsy (TLE) and sleep, exploring the bidirectional links in mechanisms and therapeutic aspects. The review reveals that sleep stages have variable impacts on seizure occurrence and the development of TLE, while TLE affects sleep micro- and macroarchitecture. Sleep characteristics may aid in localizing properties in persons with drug resistant epilepsy, and effective epilepsy surgery may improve sleep abnormalities. Furthermore, sleep abnormalities also seem to influence memory, language, and cognitive-executive function in TLE. Limited literature focused on specific aspects of TLE and sleep necessitates future investigations to understand the pathogenetic mechanisms linking sleep abnormalities to epilepsy outcomes in the important sub-population of TLE.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Jennifer M. Cori, Christopher Gordon, Melinda L. Jackson, Allison Collins, Rohit Philip, David Stevens, Aqsa Naqvi, Ruth Hosking, Clare Anderson, Maree Barnes, Mark E. Howard, Andrew Vakulin
Summary: The study found that older individuals with obstructive sleep apnea (OSA) were less susceptible to fatigue-related driving impairment compared to younger individuals when assessed in nighttime after extended wakefulness. Further research is needed to determine if this also applies to various challenging driving scenarios.
Article
Clinical Neurology
Erika M. Yamazaki, Caroline A. Antler, Charlotte R. Lasek, Namni Goel
Summary: The study aimed to investigate the recovery patterns and differences after total sleep deprivation (TSD) and chronic sleep restriction (SR). Results showed that deficits in cognitive performance, self-reported sleepiness, and other measures were reversed after recovery sleep, except for some measures which failed to completely recover. This suggests that TSD and SR induce sustained, differential biological, physiological, and/or neural changes that are not reversed with chronic, long-duration recovery sleep.
Article
Clinical Neurology
Igor Radun, Andres Levitski, Mattias Wahde, Michael Ingre, Ola Benderius, Jenni Radun, Goran Kecklund
Summary: The study results indicate that driving in demanding road conditions (i.e. slippery road) might further exhaust already sleepy drivers, although this is not clearly reflected in driving performance.
JOURNAL OF SLEEP RESEARCH
(2022)
Article
Clinical Neurology
Markku Partinen, Bjorn Bjorvatn, Brigitte Holzinger, Frances Chung, Thomas Penzel, Colin A. Espie, Charles M. Morin
Summary: This international collaboration project aims to investigate the sleep habits and symptoms of adults from different countries during the COVID-19 pandemic. A harmonised questionnaire with multiple languages was developed for anonymous cross-sectional surveys and prospective research.
JOURNAL OF SLEEP RESEARCH
(2021)
Article
Clinical Neurology
Melanie Strauss, Lucie Griffon, Maxime Elbaz, Isabelle Arnulf, Mounir Chennaoui, Damien Leger
Summary: This study examines decision-making impairments in individuals with central disorders of hypersomnolence (CDH), specifically narcolepsy type 1 (NT1). The results suggest that both NT1 and other CDH patients have decreased learning abilities to avoid losses, which is associated with alterations in vigilance. The study provides new insights into the nature of decision-making impairments in CDH and suggests the potential for minimizing these alterations by restoring adequate vigilance.
Article
Clinical Neurology
Kyriakos Dimitriadis, Christina Stathakopoulou, Nikolaos Pyrpyris, Eirini Beneki, Elena Adamopoulou, Stergios Soulaidopoulos, Ioannis Leontsinis, Alexandros Kasiakogias, Aggelos Papanikolaou, Panagiotis Tsioufis, Konstantinos Aznaouridis, Dimitris Tsiachris, Konstantina Aggeli, Konstantinos Tsioufis
Summary: This review provides a comprehensive analysis of the common pathophysiology between sleep disordered breathing (SDB) and mitral regurgitation (MR), and discusses the effects of SDB treatment on MR and the effects of mitral valve surgery or transcatheter repair on obstructive and central sleep apnea (OSA and CSA).
Article
Clinical Neurology
Szu-Yu Hou, Ching-Ju Chiu, Jeanne Laraine Shea, Chih-Liang Wang, Hsiao-Han Tang, Po-Ching Kuo, Yi-Chieh Yang, Chih-Hsing Wu
Summary: The study aimed to examine the effects of age, menopausal status, and symptoms on sleep patterns and circadian rhythms in midlife women. Premenopausal women had the most unstable day-to-day rhythms, and women with more severe symptoms experienced greater sleep problems. Psychological symptoms were the strongest predictors for all sleep parameters.
Article
Clinical Neurology
Ya-Wen Hsiao, Wei-Lun Lin, Yu-Hui Chou, Shin-Huei Liu, Ting-Wei Ernie Liao, Shih-Ann Chen, Li-Wei Lo
Summary: This study aimed to investigate the effects of RDN on heart inflammation associated with COSA. The results suggest that RDN treatment may prevent COSA-associated heart inflammation through the JAK2-STAT3 signaling pathway.
Article
Clinical Neurology
Amy C. Reynolds, Kelly A. Loffler, Nicole Grivell, Brandon W. J. Brown, Robert J. Adams
Summary: This study aimed to understand the experience of sleep disorder diagnosis and treatment in shift workers and propose patient-informed solutions to improve access to health services. The findings showed that there were varied experiences with diagnosis and management, often taking a long time to seek help from healthcare providers after noticing symptoms. The study also identified the need for education and awareness initiatives, convenient screening and referral pathways, and tailored models of care.
Article
Clinical Neurology
Hsi -Chung Chen, Nai-Wei Hsu, Ching-Heng Lin
Summary: This study found a relationship between daytime sleepiness and mortality risk among older adults. The moderating effects of sex and physical function were examined. Specifically, the passive factor predicted mortality risk in women with good muscle power, while the active factor predicted mortality risk in men with good muscle power.
Article
Clinical Neurology
Sean P. A. Drummond, Bei Bei
Summary: This study proposes a parsimonious two-stage model for defining stages of Cognitive Behavioural Therapy for Insomnia (CBT-I) based on Sleep Restriction Therapy (SRT). Using data from a randomized clinical trial, the model helps identify patterns of treatment progression and their association with baseline insomnia severity. The model holds potential for further research on various CBT-I processes that are currently not fully understood.
Article
Clinical Neurology
Janet Jezkova, Karel Sonka, Jakub Kreisinger, Petra Prochazkova, Helena Tlaskalova-Hogenova, Sona Nevsimalova, Jitka Buskova, Radana Merkova, Tereza Dvorakova, Iva Prihodova, Simona Dostalova, Radka Roubalova
Summary: In recent years, there has been a growing interest in the influence of gut microbiota on sleep physiology. The gut microbiota affects the central nervous system and circadian rhythms, and can be associated with sleep disorders. This study observed the gut microbiota composition of patients with different types of narcolepsy and idiopathic hypersomnia, and found changes in beta diversity in these patient groups compared to healthy controls. However, after adjusting for confounding factors, the differences were no longer statistically significant. The study suggests that using metabolomics and proteomics approaches to study the role of microbiota in sleep disorders may be beneficial.
Article
Clinical Neurology
Mauro Manconi, Linda C. van der Gaag, Francesca Mangili, Corrado Garbazza, Silvia Riccardi, Christian Cajochen, Susanna Mondini, Francesca Furia, Elena Zambrelli, Simone Baiardi, Alessandra Giordano, Nicola Rizzo, Cristina Fonti, Elsa Viora, Armando D'Agostino, Alessandro Cicolin, Fabio Cirignotta, Daniele Aquilino, Alessandra Barassi, Renata del Giudice, Giulia Fior, Orsola Gambini, Barbara Giordano, Alma Martini, Chiara Serrati, Rossana Stefanelli, Silvio Scarone, Mariapaola Canevini, Valentina Fanti, Hans-Christian Stein, Anna Maria Marconi, Erica Raimondo, Emanuela Viglietta, Rossella Santoro, Giuliana Simonazzi, Alessandra Bianconcini, Francesco Meani, Nicoletta Piazza, Filippos Filippakos, Thomas Gyr
Summary: The Life-ON study provides the largest polysomnographic dataset coupled with longitudinal subjective assessments of sleep quality in pregnant women to date. Sleep disorders are highly frequent and distributed differently during pregnancy and postpartum. Routine assessment of sleep disturbances in the perinatal period is necessary to improve early detection and clinical management.
Article
Clinical Neurology
Zhihua Huang, Anqi Duan, Zhihui Zhao, Qing Zhao, Yi Zhang, Xin Li, Sicheng Zhang, Luyang Gao, Chenhong An, Qin Luo, Zhihong Liu
Summary: This study aims to investigate pulmonary arterial hypertension (PAH) phenotypes and their prognostic implications by clustering overnight cardiorespiratory signals in PAH patients. Three distinct clusters were identified, with patients in Cluster 3 exhibiting worse clinical outcomes. The presence of nocturnal hypoxemia and obstructive sleep apnea (OSA) in PAH patients was associated with increased risk of clinical worsening. Tailored management strategies addressing both PAH and nocturnal hypoxemia may improve clinical outcomes.
Article
Clinical Neurology
Yudan Lv, Yujun Wen, Ramalingam Vetrivelan, Jun Lu
Summary: This study demonstrated that the projections from the pontine parabrachial nucleus (PB) to the basal forebrain (BF) and medial septum (MS) can activate the cerebral cortex and hippocampus, providing important insights into the activities of these brain regions during the sleep-wake cycle.
Article
Clinical Neurology
Annika M. Myers, Megan E. Rech, Bengi Baran, Cara Palmer, Dimitrios Mylonas, Candice A. Alfano
Summary: This study found that N2 sleep spindles are associated with emotional functioning in school-aged children. Higher spindle density is related to decreased state-based emotional arousal towards negative affective images, and higher spindle peak frequency is associated with greater use of the positive emotion regulatory strategy of savoring.
Article
Clinical Neurology
Hung Youl Seok, Yong Won Cho
Summary: This study investigated the long-term impact of dopamine agonist treatment on altered central sensory processing in restless legs syndrome (RLS) patients. The results showed that dopamine agonist treatment effectively reduced RLS symptoms but did not reverse the altered central sensory processing observed on testing. These findings suggest that RLS pathophysiology is multifactorial and not solely driven by dopaminergic dysfunction.