Article
Nutrition & Dietetics
Barbara D. Pachikian, Sylvie Copine, Marlene Suchareau, Louise Deldicque
Summary: The study found that supplementing with saffron extract for 6 weeks led to improvements in sleep duration and quality, including increased time in bed, improved ease of falling asleep, and overall improvement in sleep quality. This suggests that saffron extract may be a natural and safe nutritional strategy to improve sleep.
Article
Health Care Sciences & Services
Syed Afroz Keramat, Vanessa Lee, Rajat Patel, Rubayyat Hashmi, Tracy Comans
Summary: This study examined the association between cognitive impairment and health-related quality of life (HRQoL) in older Australians. The results showed that moderate and severe cognitive impairment were negatively associated with HRQoL. These findings are important for future interventions and cost-effectiveness analyses targeting cognitive impairment.
QUALITY OF LIFE RESEARCH
(2023)
Article
Clinical Neurology
Martin Broberg, Viola Helaakoski, Tuomo Kiiskinen, Tiina Paunio, Samuel E. Jones, Nina Mars, Jacqueline M. Lane, Richa Saxena, Hanna M. Ollila
Summary: The study aims to elucidate the genetic risk factors and clinical correlates of sleep medication purchase and estimate the comorbid impact of sleep problems. The researchers identified 27 genetic loci significantly associated with sleep medication and highlighted the genetic basis for sleep problems and the association between sleep problems and psychiatric traits.
Article
Public, Environmental & Occupational Health
Syed Afroz Keramat, Khorshed Alam, Byron Keating, Bright Opoku Ahinkorah, Richard Gyan Aboagye, Abdul-Aziz Seidu, Nandeeta Samad, Monidipa Saha, Jeff Gow, J. H. Stuart Biddle, Tracy Comans
Summary: This study investigates the impact of morbid obesity and multiple long-term conditions on health-related quality of life. The findings show that both morbid obesity and MLTCs are negatively associated with HRQoL, leading to lower scores in physical and mental health components.
PREVENTIVE MEDICINE REPORTS
(2022)
Article
Health Care Sciences & Services
John Roger Andersen, Kyrre Breivik, Inger Elise Engelund, Marjolein M. Iversen, Jorunn Kirkeleit, Tone Merete Norekval, Kjersti Oterhals, Anette Storesund
Summary: This study investigated the criterion validity and convergent validity of unweighted composite scores for physical and mental health. The results showed that these scores demonstrated satisfactory validity, suggesting that the calculation of these composite scores can be kept simple.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2022)
Article
Geriatrics & Gerontology
Kelsie M. Full, Snigdha Pusalavidyasagar, Priya Palta, Kevin J. Sullivan, Jung-Im Shin, Rebecca F. Gottesman, Adam P. Spira, Matthew P. Pase, Pamela L. Lutsey
Summary: This study aimed to examine the association between the use of sleep medications and incident dementia in a community-based cohort of older adults. The results showed that sleep medication use was associated with a 48% greater risk of dementia compared to nonuse.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Clinical Neurology
Melissa Gilbertson, Cele Richardson, Peter Eastwood, Andrew Wilson, Peter Jacoby, Helen Leonard, Jenny Downs
Summary: This study found that sleep quality in children with intellectual disabilities is mainly influenced by comorbidities, rather than functional impairments. Factors such as recurrent pain, frequent seizures, coughing, constipation and prescription sleep medications are associated with abnormal sleep, with differences in predictors between diagnostic groups.
JOURNAL OF SLEEP RESEARCH
(2021)
Article
Clinical Neurology
Yan Ma, Michael R. Goldstein, Roger B. Davis, Gloria Y. Yeh
Summary: This study found significant subjective-objective sleep discrepancy in patients with insomnia and comorbid OSA, with insomnia having the strongest association with sleep discrepancy and negative impact on QOL. Patients with comorbid OSA reported the greatest sleep discrepancy and lowest QOL. Further research is needed to understand individual profiles of misperception and insomnia phenotypes.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2021)
Article
Psychology, Multidisciplinary
Dirk Hofmeister, Thomas Schulte, Anja Mehnert-Theuerkauf, Kristina Geue, Markus Zenger, Peter Esser, Heide Goetze, Andreas Hinz
Summary: It is well-known that cancer patients are more likely to experience sleep problems compared to the general population, and sleep quality is associated with various aspects of quality of life. Female and younger cancer patients are particularly at risk for sleep problems.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Multidisciplinary Sciences
Rebecca Jane Scarratt, Ole Adrian Heggli, Peter Vuust, Kira Vibe Jespersen
Summary: This study extracted audio features from a large number of tracks in sleep playlists on Spotify and found that sleep music is softer, slower, more often instrumental, and played on acoustic instruments compared to general music. However, there is a large amount of variation in sleep music, which can be grouped into six distinct subgroups. Interestingly, some popular tracks in sleep music are faster, louder, and more energetic than average sleep music. This research advances our understanding of how people use music to regulate their behavior in everyday life by determining the universal and subgroup characteristics of sleep music in a unique, global dataset using digital traces.
Article
Oncology
Meera Legg, Ree M. Meertens, Eline van Roekel, Stephanie O. Breukink, Maryska L. Janssen, Eric T. P. Keulen, Karen Steindorf, Matty P. Weijenberg, Martijn Bours
Summary: This study aimed to investigate the association between sleep quality and fatigue in colorectal cancer survivors. The results showed that worse sleep quality in colorectal cancer patients was associated with higher levels of fatigue during the first two years post-treatment. Therefore, attention should be paid to sleep quality and sleep health interventions may help reduce fatigue and improve quality of life in colorectal cancer survivors.
Article
Multidisciplinary Sciences
Takefumi Tsunemitsu, Yuki Kataoka, Masaru Matsumoto, Takashi Hashimoto, Takao Suzuki
Summary: Early enteral administration of sleep-promoting medication was found to lower the average daily propofol dose per body weight in mechanically ventilated patients without increasing adverse events, and may lead to a reduction in the total cost of neuroactive drugs.
Article
Clinical Neurology
Margot W. L. Morssinkhof, Chantal M. Wiepjes, Breanna W. Bosman, Jim Kinds, Alessandra D. Fisher, Yona Greenman, Baudewijntje P. C. Kreukels, Guy T'Sjoen, Ysbrand D. van der Werf, Martin den Heijer, Birit F. P. Broekman
Summary: This study examines the effects of 12 months of gender-affirming hormone therapy (GAHT) on sleep quality and insomnia severity. The results show that GAHT does not result in significant changes in insomnia or sleep quality, but there are small improvements in sleep efficiency and sleep onset latency after 12 months.
Article
Medicine, General & Internal
Tingting Geng, Xiang Li, Hao Ma, Yoriko Heianza, Lu Qi
Summary: The study demonstrates an inverse association between a healthy sleep pattern and the risk of chronic kidney disease (CKD), with stronger effects seen in individuals without a history of hypertension and in younger age groups.
MAYO CLINIC PROCEEDINGS
(2022)
Article
Clinical Neurology
Magdy Younes, Bethany Gerardy, Allan Pack, Samuel T. Kuna, Cecilia Castro-Diehl, Susan Redline
Summary: Conventional metrics for measuring sleep quantity/depth have limitations. An ORP-based approach provides additional information on sleep disorders that is not captured by traditional metrics. The ORP histogram offers unique insights into the neurophysiological characteristics of sleep disorders, potentially advancing diagnosis and management.
Article
Biology
Atsushi Haraguchi, Yoko Komada, Yuichi Inoue, Shigenobu Shibata
CHRONOBIOLOGY INTERNATIONAL
(2019)
Editorial Material
Clinical Neurology
Yoko Komada
SLEEP AND BIOLOGICAL RHYTHMS
(2020)
Article
Medicine, General & Internal
Kentaro Matsui, Yoko Komada, Katsuji Nishimura, Kenichi Kuriyama, Yuichi Inoue
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Clinical Neurology
Kentaro Matsui, Kenichi Kuriyama, Takuya Yoshiike, Kentaro Nagao, Naoko Ayabe, Yoko Komada, Isa Okajima, Wakako Ito, Jun Ishigooka, Katsuji Nishimura, Yuichi Inoue
Article
Multidisciplinary Sciences
Maria Korman, Vadim Tkachev, Catia Reis, Yoko Komada, Shingo Kitamura, Denis Gubin, Vinod Kumar, Till Roenneberg
SCIENTIFIC REPORTS
(2020)
Review
Environmental Sciences
Yoko Komada, Isa Okajima, Tamotsu Kuwata
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Article
Clinical Neurology
Yuta Kanda, Yoshikazu Takaesu, Mina Kobayashi, Yoko Komada, Kunihiro Futenma, Isa Okajima, Koichiro Watanabe, Yuichi Inoue
Summary: The study found that the J-BRIAN-SR is a valid and reliable tool for screening and evaluating DSWPD, with an overall reliability coefficient of 0.82. Exploratory factor analysis revealed that the J-BRIAN-SR consists of three factors. A score of 40 points provided 80.0% sensitivity and 75.6% specificity for DSWPD positivity.
Article
Environmental Sciences
Isa Okajima, Yoko Komada, Wakako Ito, Yuichi Inoue
Summary: The study revealed that the impact of sleep debt on daytime sleepiness, mood, and work performance was greater than that of social jetlag, although both had negative impacts on these aspects.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Pediatrics
Yoko Komada, Yoshiki Ishibashi, Shunta Hagiwara, Mariko Kobori, Akiyoshi Shimura
Summary: The study revealed that during the COVID-19 school closure, a less restrictive school schedule led to decreased sleepiness in children, which was associated with decreasing social jetlag.
Article
Environmental Sciences
Yoko Komada, Makoto Sato, Yuko Ikeda, Azusa Kami, Chika Masuda, Shigenobu Shibata
Summary: The study found no association between menstrual cycle onset and lunar phase, but discovered that a higher proportion of good sleepers had their menstrual cycle beginning during the light period, while a higher proportion of poor sleepers had it begin during the dark period. Menstrual cycle onset during the dark period was associated with poorer subsequent subjective sleep quality, particularly with consecutive onsets during the dark period or at a rapidly changing lunar phase.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Clinical Neurology
Maria Korman, Vadim Tkachev, Catia Reis, Yoko Komada, Shingo Kitamura, Denis Gubin, Vinod Kumar, Till Roenneberg
Summary: In this study, changes in wellbeing during COVID-19 social restrictions were investigated, and their relationship with outdoor daylight exposure and sleep-wake behavior was analyzed. The results showed that sleep quality, quality of life, physical activity, and productivity declined during social restrictions, while screen time increased and outdoor daylight exposure decreased. However, some participants reported no changes or even improvements. Larger reductions in outdoor daylight exposure were associated with poorer wellbeing and delayed mid-sleep times.
JOURNAL OF SLEEP RESEARCH
(2022)
Article
Biology
Norihisa Tamura, Yoko Komada, Yuichi Inoue, Hideki Tanaka
Summary: This study found that social jetlag is highly prevalent among Japanese adolescents and could be a major risk factor for irritable mood, daytime sleepiness, and poor academic performance.
CHRONOBIOLOGY INTERNATIONAL
(2022)
Article
Biology
Kosuke Tanioka, Momoko Kayaba, Sayaka Tomishima, Yoko Komada, Yuichi Inoue
Summary: This study examined sleep behaviors and issues in young people in Japan before and after the COVID-19 pandemic. Results showed a significant delay in sleep phase during the pandemic, but improvements were seen in total sleep time, social jetlag, and psychological health after the pandemic.
CHRONOBIOLOGY INTERNATIONAL
(2022)
Article
Nutrition & Dietetics
Kentaro Matsui, Yoko Komada, Isa Okajima, Yoshikazu Takaesu, Kenichi Kuriyama, Yuichi Inoue
Summary: This study aimed to investigate the differences between the two core symptoms of night eating syndrome in the general Japanese population. The results showed that participants with evening hyperphagia and nocturnal ingestion had higher levels of anxiety and depression compared to those without NES. Evening hyperphagia was associated with higher BMI, shorter sleep duration, later sleep-wake schedule, and higher insomnia score, while nocturnal ingestion was associated with younger age, smoking habit, living alone, earlier sleep-wake schedule, and higher insomnia score. The characteristics of sleep duration and sleep-wake schedule in the two groups were opposite, suggesting differences in the sleep pathophysiology mechanisms.
Article
Obstetrics & Gynecology
Sho-Ichi Kawakami, Azusa Ikegami, Yoko Komada
Summary: This study aimed to describe sleep problems and habits among Japanese women in different gestational stages. The results showed that pregnant women had poorer sleep quality in late pregnancy and the first week postpartum, with a higher risk of sleep-disordered breathing.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
(2023)
Article
Clinical Neurology
Melanie Strauss, Lucie Griffon, Maxime Elbaz, Isabelle Arnulf, Mounir Chennaoui, Damien Leger
Summary: This study examines decision-making impairments in individuals with central disorders of hypersomnolence (CDH), specifically narcolepsy type 1 (NT1). The results suggest that both NT1 and other CDH patients have decreased learning abilities to avoid losses, which is associated with alterations in vigilance. The study provides new insights into the nature of decision-making impairments in CDH and suggests the potential for minimizing these alterations by restoring adequate vigilance.
Article
Clinical Neurology
Kyriakos Dimitriadis, Christina Stathakopoulou, Nikolaos Pyrpyris, Eirini Beneki, Elena Adamopoulou, Stergios Soulaidopoulos, Ioannis Leontsinis, Alexandros Kasiakogias, Aggelos Papanikolaou, Panagiotis Tsioufis, Konstantinos Aznaouridis, Dimitris Tsiachris, Konstantina Aggeli, Konstantinos Tsioufis
Summary: This review provides a comprehensive analysis of the common pathophysiology between sleep disordered breathing (SDB) and mitral regurgitation (MR), and discusses the effects of SDB treatment on MR and the effects of mitral valve surgery or transcatheter repair on obstructive and central sleep apnea (OSA and CSA).
Article
Clinical Neurology
Szu-Yu Hou, Ching-Ju Chiu, Jeanne Laraine Shea, Chih-Liang Wang, Hsiao-Han Tang, Po-Ching Kuo, Yi-Chieh Yang, Chih-Hsing Wu
Summary: The study aimed to examine the effects of age, menopausal status, and symptoms on sleep patterns and circadian rhythms in midlife women. Premenopausal women had the most unstable day-to-day rhythms, and women with more severe symptoms experienced greater sleep problems. Psychological symptoms were the strongest predictors for all sleep parameters.
Article
Clinical Neurology
Ya-Wen Hsiao, Wei-Lun Lin, Yu-Hui Chou, Shin-Huei Liu, Ting-Wei Ernie Liao, Shih-Ann Chen, Li-Wei Lo
Summary: This study aimed to investigate the effects of RDN on heart inflammation associated with COSA. The results suggest that RDN treatment may prevent COSA-associated heart inflammation through the JAK2-STAT3 signaling pathway.
Article
Clinical Neurology
Amy C. Reynolds, Kelly A. Loffler, Nicole Grivell, Brandon W. J. Brown, Robert J. Adams
Summary: This study aimed to understand the experience of sleep disorder diagnosis and treatment in shift workers and propose patient-informed solutions to improve access to health services. The findings showed that there were varied experiences with diagnosis and management, often taking a long time to seek help from healthcare providers after noticing symptoms. The study also identified the need for education and awareness initiatives, convenient screening and referral pathways, and tailored models of care.
Article
Clinical Neurology
Hsi -Chung Chen, Nai-Wei Hsu, Ching-Heng Lin
Summary: This study found a relationship between daytime sleepiness and mortality risk among older adults. The moderating effects of sex and physical function were examined. Specifically, the passive factor predicted mortality risk in women with good muscle power, while the active factor predicted mortality risk in men with good muscle power.
Article
Clinical Neurology
Sean P. A. Drummond, Bei Bei
Summary: This study proposes a parsimonious two-stage model for defining stages of Cognitive Behavioural Therapy for Insomnia (CBT-I) based on Sleep Restriction Therapy (SRT). Using data from a randomized clinical trial, the model helps identify patterns of treatment progression and their association with baseline insomnia severity. The model holds potential for further research on various CBT-I processes that are currently not fully understood.
Article
Clinical Neurology
Janet Jezkova, Karel Sonka, Jakub Kreisinger, Petra Prochazkova, Helena Tlaskalova-Hogenova, Sona Nevsimalova, Jitka Buskova, Radana Merkova, Tereza Dvorakova, Iva Prihodova, Simona Dostalova, Radka Roubalova
Summary: In recent years, there has been a growing interest in the influence of gut microbiota on sleep physiology. The gut microbiota affects the central nervous system and circadian rhythms, and can be associated with sleep disorders. This study observed the gut microbiota composition of patients with different types of narcolepsy and idiopathic hypersomnia, and found changes in beta diversity in these patient groups compared to healthy controls. However, after adjusting for confounding factors, the differences were no longer statistically significant. The study suggests that using metabolomics and proteomics approaches to study the role of microbiota in sleep disorders may be beneficial.
Article
Clinical Neurology
Mauro Manconi, Linda C. van der Gaag, Francesca Mangili, Corrado Garbazza, Silvia Riccardi, Christian Cajochen, Susanna Mondini, Francesca Furia, Elena Zambrelli, Simone Baiardi, Alessandra Giordano, Nicola Rizzo, Cristina Fonti, Elsa Viora, Armando D'Agostino, Alessandro Cicolin, Fabio Cirignotta, Daniele Aquilino, Alessandra Barassi, Renata del Giudice, Giulia Fior, Orsola Gambini, Barbara Giordano, Alma Martini, Chiara Serrati, Rossana Stefanelli, Silvio Scarone, Mariapaola Canevini, Valentina Fanti, Hans-Christian Stein, Anna Maria Marconi, Erica Raimondo, Emanuela Viglietta, Rossella Santoro, Giuliana Simonazzi, Alessandra Bianconcini, Francesco Meani, Nicoletta Piazza, Filippos Filippakos, Thomas Gyr
Summary: The Life-ON study provides the largest polysomnographic dataset coupled with longitudinal subjective assessments of sleep quality in pregnant women to date. Sleep disorders are highly frequent and distributed differently during pregnancy and postpartum. Routine assessment of sleep disturbances in the perinatal period is necessary to improve early detection and clinical management.
Article
Clinical Neurology
Zhihua Huang, Anqi Duan, Zhihui Zhao, Qing Zhao, Yi Zhang, Xin Li, Sicheng Zhang, Luyang Gao, Chenhong An, Qin Luo, Zhihong Liu
Summary: This study aims to investigate pulmonary arterial hypertension (PAH) phenotypes and their prognostic implications by clustering overnight cardiorespiratory signals in PAH patients. Three distinct clusters were identified, with patients in Cluster 3 exhibiting worse clinical outcomes. The presence of nocturnal hypoxemia and obstructive sleep apnea (OSA) in PAH patients was associated with increased risk of clinical worsening. Tailored management strategies addressing both PAH and nocturnal hypoxemia may improve clinical outcomes.
Article
Clinical Neurology
Yudan Lv, Yujun Wen, Ramalingam Vetrivelan, Jun Lu
Summary: This study demonstrated that the projections from the pontine parabrachial nucleus (PB) to the basal forebrain (BF) and medial septum (MS) can activate the cerebral cortex and hippocampus, providing important insights into the activities of these brain regions during the sleep-wake cycle.
Article
Clinical Neurology
Annika M. Myers, Megan E. Rech, Bengi Baran, Cara Palmer, Dimitrios Mylonas, Candice A. Alfano
Summary: This study found that N2 sleep spindles are associated with emotional functioning in school-aged children. Higher spindle density is related to decreased state-based emotional arousal towards negative affective images, and higher spindle peak frequency is associated with greater use of the positive emotion regulatory strategy of savoring.
Article
Clinical Neurology
Hung Youl Seok, Yong Won Cho
Summary: This study investigated the long-term impact of dopamine agonist treatment on altered central sensory processing in restless legs syndrome (RLS) patients. The results showed that dopamine agonist treatment effectively reduced RLS symptoms but did not reverse the altered central sensory processing observed on testing. These findings suggest that RLS pathophysiology is multifactorial and not solely driven by dopaminergic dysfunction.
