Article
Clinical Neurology
Wenxin Liu, Qingqing Du, Hong Zhang, Dingding Han
Summary: Obstructive sleep apnea syndrome (OSAS) in children is a significant public health issue that affects the physical and mental growth. OSAS alters the composition of the gut microbiome, affecting sleep patterns and leading to comorbidities such as obesity, hypertension, and cardiovascular disease.
Article
Clinical Neurology
Hiwa Mohammadi, Ardalan Aarabi, Mohammad Rezaei, Habibolah Khazaie, Serge Brand
Summary: The study found that individuals with OSAS have significantly lower spindle density in N3 and shorter spindle duration in N2 compared to healthy controls. Furthermore, individuals with mild OSAS showed sleep spindle characteristics more similar to healthy controls, unlike those with moderate and severe OSAS.
FRONTIERS IN NEUROLOGY
(2021)
Article
Neurosciences
Xiaofeng Su, Yinghui Gao, Weihao Xu, JianHua Li, Kaibing Chen, Yan Gao, JingJing Guo, LiBo Zhao, Huanhuan Wang, Xiaoshun Qian, Junling Lin, Jiming Han, Lin Liu
Summary: The study found that increased Cystatin C (Cys-C) concentration is a risk factor for stroke incidence in elderly patients with obstructive sleep apnea (OSA), especially in patients older than 70 years.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Medicine, Research & Experimental
Kun-Tai Kang, Te-Huei Yeh, Ying-Shuo Hsu, Jenq-Yuh Ko, Chia-Hsuan Lee, Ming-Tzer Lin, Wei-Chung Hsu
Summary: The meta-analysis found that sleep surgery for obstructive sleep apnea in adults led to a significant reduction in CRP levels. The greatest reduction in CRP levels was observed in patients with a postoperative AHI reduction of more than 20 events/hr.
Article
Clinical Neurology
Lucia Spicuzza, Gianluca Sambataro, Matteo Schisano, Giuseppe Ielo, Salvatore Mancuso, Carlo Vancheri
Summary: The study assesses the usefulness of nocturnal oxygen therapy via nasal high flow (NHF-OT) as a possible alternative to oxygen-enriched positive airway pressure (PAP) in patients with the coexistence of obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD), known as overlap syndrome (OS), and concludes that NHF-OT significantly reduces obstructive episodes and improves oxygenation in elderly patients with OS.
SLEEP AND BREATHING
(2023)
Article
Critical Care Medicine
Fenqing Shang, Shen-Chih Wang, Brendoan Gongol, So Yun Han, Yoshitake Cho, Cara R. Schiavon, Lili Chen, Yuanming Xing, Yingshuai Zhao, Ming'an Ning, Xuan Guo, Fangzhou He, Yuyang Lei, Liuyi Wang, Uri Manor, Traci Marin, Kun-Ta Chou, Ming He, Po-Hsun Huang, John Y-J Shyy, Atul Malhotra
Summary: This study identified the mechanism of endothelial cell dysfunction induced by obstructive sleep apnea (OSA) and explored potential therapies for OSA-accelerated cardiovascular disease. The study found that miR-210 is associated with OSA and can induce EC dysfunction by regulating mitochondrial function. Additionally, the SREBP2 inhibitor betulin can alleviate the increased systolic blood pressure caused by OSA.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Clinical Neurology
Jonathan D. Santoro, Justin Del Rosario, Beth Osterbauer, Emily S. Gillett, Debra M. Don
Summary: An analysis of sleep positions in children with both Down syndrome and obstructive sleep apnea found a preference for lateral sleeping positions, potentially optimizing airflow but not correlated with the severity of OSA.
Article
Neurosciences
Naikai Shi, Feng Pang, Jin Chen, Minmin Lin, Jiuxing Liang
Summary: This study aims to find potential biomarkers for obstructive sleep apnea hypopnea syndrome in children by investigating the patterns of sleep electroencephalography networks. The results showed that there were significant differences in information flow patterns between children with obstructive sleep apnea hypopnea syndrome and healthy controls, which could potentially serve as biomarkers.
Article
Endocrinology & Metabolism
Milina Tancic-Gajic, Miodrag Vukcevic, Miomira Ivovic, Ljiljana V. Marina, Zorana Arizanovic, Ivan Soldatovic, Milos Stojanovic, Aleksandar Dogo, Aleksandra Kendereski, Svetlana Vujovic
Summary: The study suggests that obstructive sleep apnea is associated with lower total and free testosterone levels in severely obese men. This finding indicates a potential impact of sleep disorders on sex hormone levels.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Clinical Neurology
Eunhye Bae, Nakwon Kwak, Sun Mi Choi, Jinwoo Lee, Young Sik Park, Chang-Hoon Lee, Sang-Min Lee, Chul-Gyu Yoo, Jaeyoung Cho
Summary: This study assessed mortality in patients with chronic obstructive pulmonary disease (COPD), obstructive sleep apnea (OSA), and overlap syndrome, and found that patients with overlap syndrome had increased mortality, although not higher than those with COPD alone. In predicting mortality, measurement of hypoxemic load was found to be more accurate than the apnea-hypopnea index.
Article
Neurosciences
Tianfeng Peng, Shan Yuan, Wenjing Wang, Zhuanyun Li, Ayshat Mussa Jumbe, Yaling Yu, Zhenghao Hu, Ruijie Niu, Xiaorong Wang, Jinnong Zhang
Summary: This study aimed to analyze the clinical characteristics of patients with COPD and OSA overlap syndrome (OS) and develop a nomogram for predicting OSA. The results identified several valuable predictors for predicting OSA, including age, type 2 diabetes, neck circumference, dyspnea scale, sleep apnea clinical score, and C-reactive protein. The nomogram showed good discrimination and calibration.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Otorhinolaryngology
Christine H. Heubi, Philip Knollman, Susan Wiley, Sally R. Shott, David F. Smith, Stacey L. Ishman, Jareen Meinzen-Derr
Summary: In children with Down syndrome, 32.5% had sleep efficiency <80%; 75.6% had an elevated arousal index; and 15.9% had total sleep time <360 minutes. More than a third of the patients had >= 3 markers of poor sleep architecture. There was no difference in children with or without obstructive sleep apnea.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Review
Medicine, General & Internal
Almala Pinar Ergenekon, Yasemin Gokdemir, Refika Ersu
Summary: Obstructive sleep apnea (OSA) is a condition characterized by recurrent blockage of the upper airway, affecting both obese and otherwise healthy children. Medical treatment options for OSA in children, including positive airway pressure treatment, are effective but have low adherence rates. This review article aims to summarize these treatment options.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pediatrics
Yingge Wang, Ying Chen, Wei Lin, Min Huang, Yuanteng Xu, Guohao Chen
Summary: The objective of this study was to evaluate the serum inflammatory markers in children with and without OSAS, including YKL-40, Interleukin-6 (IL-6), Interleukin-8 (IL-8), Interleukin-10 (IL-10), TNF-alpha, and CRP. The ELISA technique was used to measure the concentration of these markers in the serum of 83 children with OSAS and 83 children without OSAS. The results showed that children with OSAS had increased levels of YKL-40, IL-6, IL-8, and IL-10 in their serum. YKL-40 and IL-8 may serve as serum inflammatory markers for the diagnosis of children with OSAS.
FRONTIERS IN PEDIATRICS
(2023)
Article
Clinical Neurology
Par Hedberg, Eva Nohlert, Ake Tegelberg
Summary: In a randomized controlled pilot trial, the effect of oral appliance therapy on inflammatory biomarkers in patients with obstructive sleep apnea (OSA) and systemic hypertension was assessed. The study found that after 3 months of treatment, there was a significant reduction in the apnea-hypopnea index in the active mandible protruded group compared to the passive mandible non-protruded group. However, there were no significant differences in the circulating concentrations of common inflammatory markers between the two treatment groups.
JOURNAL OF SLEEP RESEARCH
(2021)
Article
Psychology, Developmental
Eunyeong Jang, Solbi Kang, Bei Bei, Seockhoon Chung, Michael Gradisar, Michal Kahn, Natalie Barnett, Sooyeon Suh
Summary: This study developed an assessment tool called PUMBA-Q to measure parental understanding and misperceptions about baby's sleep. The questionnaire was validated using self-report and objective sleep measures. The results showed the link between parental cognitions and child sleep, highlighting the importance of managing parental cognitions about child sleep when treating pediatric sleep problems.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Psychiatry
Jihoon Hong, C. Hyung Keun Park, Harin Kim, Youjin Hong, Junseok Ahn, Jin Yong Jun, Jangho Park, Jeong Hye Kim, Young Rong Bang, Seockhoon Chung
Summary: This study aimed to investigate whether the psychological states of nursing professionals affect their grief response for COVID-19 patients' death. A survey was conducted among frontline nursing professionals in COVID-19 inpatients wards, and their responses to rating scales were collected. The results showed that nursing professionals' depression directly influenced their grief reaction, and work-related stress, viral anxiety, insomnia severity, and loneliness partially mediated the association.
PSYCHIATRY INVESTIGATION
(2023)
Article
Psychiatry
Mingeol Park, Jihoon Hong, Jangho Park, Seockhoon Chung
Summary: This study aimed to investigate the association between academic stress or motivation and the psychological well-being of medical students during the COVID-19 pandemic. The results showed that resilience plays an important role in mediating the relationship between intrinsic motivation and psychological well-being or academic stress, while viral anxiety is not a mediator in this relationship.
PSYCHIATRY INVESTIGATION
(2023)
Article
Psychiatry
Runlian He, Xinjie Du, Oli Ahmed, Eulah Cho, Seockhoon Chung
Summary: This study aimed to investigate the psychometric properties of the Chinese version of the Stress and Anxiety to Viral Epidemics-6 Items (SAVE-6) scale for cold chain practitioners exposed to moderate-to-high risk of infection. A total of 233 cold chain practitioners participated in an online survey, which included demographic characteristics, the Chinese version of SAVE-6, the Generalized Anxiety Disorders-7 (GAD-7), and the Patient Health Questionnaire-9 (PHQ-9) scales. The Chinese version of the SAVE-6 scale showed satisfactory internal consistency and good convergent validity, and can be used as a reliable and valid rating scale to assess the anxiety response of cold chain practitioners in the post-pandemic era.
PSYCHIATRY INVESTIGATION
(2023)
Article
Psychiatry
Junseok Ahn, Young Rong Bang, Eulah Cho, Oli Ahmed, Jeong Hye Kim, Youjin Hong, Seockhoon Chung, Keith A. Anderson
Summary: During the COVID-19 pandemic, healthcare workers have experienced higher levels of anxiety and psychological stress. This study analyzed data from 229 nurses and found that the 10-item Korean version of the Grief Support in Healthcare Scale is reliable and valid for assessing psychological support for grief among frontline nursing professionals.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Jeong Hye Kim, C. Hyung Keun Park, Oli Ahmed, Youjin Hong, Seockhoon Chung, Jangho Park, Sherman A. A. Lee
Summary: This study aimed to explore the reliability and validity of the Pandemic Grief Scale (PGS) among frontline nursing professionals working in COVID-19 inpatient wards. The results showed that the PGS was valid and reliable for measuring grief reactions among nursing professionals facing the pandemic.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Omer Faruk Uygur, Oli Ahmed, Hilal Uygur, Aynur Bahar, Onur Hursitoglu, Seockhoon Chung, Christopher L. Drake
Summary: This study investigated the mediating role of sleep reactivity, sleep hygiene, and sleep effort in the relationship between Type D personality and insomnia. The results showed that individuals with Type D personality had high sleep reactivity, and individuals with a higher number of these personality traits exhibited more severe insomnia symptoms through high sleep reactivity, greater sleep effort, and worse sleep hygiene.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Health Care Sciences & Services
Miyeon Jung, Sae Byul Lee, Jong Won Lee, Yu Rang Park, Haekwon Chung, Yul Ha Min, Hye Jin Park, Minsun Lee, Seockhoon Chung, Byung Ho Son, Sei-Hyun Ahn, Il Yong Chung
Summary: This randomized controlled trial explores the effects of participating in a mobile health community on physical activity levels and mental distress in breast cancer survivors. The results showed that engagement in a mobile health community was effective in reducing mental distress and increasing physical activity in breast cancer survivors.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Clinical Neurology
Seockhoon Chung, Inn-Kyu Cho, Jiyoung Kim, Dongin Lee, Eulah Cho, Jung Mun Choi, Tae Kyoung Ha, Young Jun Lee, Ji Hyun Kim, Ji Ho Choi
Summary: The aim of this study was to evaluate the safety and efficacy of digital therapeutic application of Sleep Index-Based Treatment for Insomnia (dSIBT-I) and compare them with those of digital application of Cognitive Behavioural Therapy for Insomnia (dCBT-I). Both the dSIBT-I and dCBT-I groups showed significant improvements in Insomnia Severity Index scores at Week 4. However, at Week 2, the dSIBT-I group showed better results than the dCBT-I group in terms of both Insomnia Severity Index scores and proportion of participants whose scores were reduced to <15.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Psychiatry
Ali Kandeger, Omer Faruk Uygur, Seockhoon Chung, Elif Yavuz, Yavuz Selvi
Summary: This study examined the relationship between sleep-wake rhythms, eating behaviors, ADHD symptoms, and weight gain during the COVID-19 pandemic. The results showed that the sleep-wake phase was more delayed in the weight gain group, and they had lower oral control and higher bulimic behavior scores. The study suggests that chronotherapeutic approaches to regulate sleep-wake rhythm may help individuals control their weight during stressful periods.
PSYCHIATRY INVESTIGATION
(2023)
Article
Psychiatry
Seockhoon Chung, Han-Sung Lee, Soomin Jang, Yong-Wook Shin, Jeong-Hyun Kim, Jin Yong Jun
Summary: This study explores the feasibility of the cognitive-behavioral model of hypochondriasis in firefighters regarding COVID-19 and examines the possible role of their grief reaction and intolerance of uncertainty in this model.
PSYCHIATRY INVESTIGATION
(2023)
Article
Behavioral Sciences
Jeong Hye Kim, Seockhoon Chung
Summary: This study examined the reliability and validity of the Korean version of the Utrecht Grief Rumination Scale (UGRS) among healthcare workers and explored the potential impact of grief rumination on the cognitive-behavioral model of hypochondriasis.
BRAIN AND BEHAVIOR
(2023)
Article
Medicine, General & Internal
Harin Kim, Wonjun Ji, Jong Won Lee, Min-Woo Jo, Sung-Chol Yun, Sei Won Lee, Chang-Min Choi, Geun Dong Lee, Hui Jeong Lee, Eulah Cho, Yura Lee, Seockhoon Chung
Summary: This study examined the relationship between fear of progression (FoP), insomnia, and depression in lung cancer patients, and tested the mediation effect of cancer-related dysfunctional beliefs about sleep (C-DBS). The results showed that insomnia did not directly influence FoP, but C-DBS mediated the association. Depression directly influenced FoP, but C-DBS did not mediate this association.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Oncology
Yeon Hee Hong, Changhee Park, Haerin Paik, Kyung-Hun Lee, Jung Ryeol Lee, Wonshik Han, Seho Park, Seockhoon Chung, Hee Jeong Kim
Summary: Fertility preservation is a major concern for breast cancer patients undergoing multimodality treatment. Cryopreservation of oocytes, embryos, and ovarian tissue are currently available methods, and in vitro maturation or gonadotropin-releasing hormone agonist could also be considered. Good communication with patients in the decision-making process is essential, and timely referral to fertility specialists for individualized treatment is crucial for desirable outcomes. A multi-disciplinary team-based approach and in-depth discussion on breast cancer treatment and fertility preservation is necessary.
JOURNAL OF BREAST CANCER
(2023)
Article
Psychiatry
Inn-Kyu Cho, Han Sung Lee, Kayoung Song, Oli Ahmed, Dongin Lee, Jiyoung Kim, Eulah Cho, Soomin Jang, Jeong-Hyun Kim, Seockhoon Chung
Summary: This study examined the reliability and validity of the SAVE-9 and SAVE-6 scales for measuring viral anxiety among firefighters during the COVID-19 pandemic. The results showed that both scales are reliable and valid instruments for evaluating viral anxiety in this population.
PSYCHIATRY INVESTIGATION
(2023)