iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis

Autophagy and aging: New lessons from progeroid mice

(2014) Guillermo Mariño et al.   Autophagy

Nuclear envelope-related lipodystrophies

(2014) A.C. Guénantin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Molecular chaperones and proteostasis regulation during redox imbalance

(2014) Katerina Niforou et al.   Redox Biology

Balance between autophagic pathways preserves retinal homeostasis

(2013) Natalia Rodríguez-Muela et al.   AGING CELL

The role of mitochondrial function and cellular bioenergetics in ageing and disease

(2013) M.D. Brand et al.   BRITISH JOURNAL OF DERMATOLOGY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

What the Genetics of Lipodystrophy Can Teach Us About Insulin Resistance and Diabetes

(2013) Camille Vatier et al.   Current Diabetes Reports

l-carnitine supplementation as a potential antioxidant therapy for inherited neurometabolic disorders

(2013) Graziela S. Ribas et al.   GENE

Identification of mitochondrial dysfunction in Hutchinson–Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture

(2013) José Rivera-Torres et al.   Journal of Proteomics

Mitochondrial dysfunction and the inflammatory response

(2013) María J. López-Armada et al.   MITOCHONDRION

Melatonin and its atheroprotective effects: A review

(2013) Gaia Favero et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth

(2013) Ruiting Lin et al.   MOLECULAR CELL

Lamin A/C and emerin regulate MKL1–SRF activity by modulating actin dynamics

(2013) Chin Yee Ho et al.   NATURE

Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway

(2013) B. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lamin A deregulation in human mesenchymal stem cells promotes an impairment in their chondrogenic potential and imbalance in their response to oxidative stress

(2013) Jesús Mateos et al.   Stem Cell Research

Mitochondrial dysfunction increases inflammatory responsiveness to cytokines in normal human chondrocytes

(2012) Carlos Vaamonde-García et al.   ARTHRITIS AND RHEUMATISM

Palmitoylated calnexin is a key component of the ribosome-translocon complex

(2012) Asvin KK Lakkaraju et al.   EMBO JOURNAL

Oxydative stress alters nuclear shape through lamins dysregulation

(2012) Aurélia Barascu et al.   Nucleus

Autophagy activation by rapamycin reduces severity of experimental osteoarthritis

(2011) Beatriz Caramés et al.   ANNALS OF THE RHEUMATIC DISEASES

Cell line models for differentiation: preadipocytes and adipocytes

(2011) Sylvia P Poulos et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Lamin A, farnesylation and aging

(2011) Sita Reddy et al.   EXPERIMENTAL CELL RESEARCH

Proteomic Profiling of Adipose Tissue from Zmpste24−/−Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing

(2011) Juan R. Peinado et al.   MOLECULAR & CELLULAR PROTEOMICS

Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease

(2010) Fernando G. Osorio et al.   AGING CELL

An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria

(2010) B. S. J. Davies et al.   HUMAN MOLECULAR GENETICS

Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin

(2010) Shao H. Yang et al.   HUMAN MOLECULAR GENETICS

Hutchinson-Gilford progeria syndrome

(2010) UmaShankar Agarwal et al.   Indian Journal of Dermatology Venereology & Leprology

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

(2010) D. Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Diseases of the Nuclear Envelope

(2010) H. J. Worman et al.   Cold Spring Harbor Perspectives in Biology

Development and implementation of standardized respiratory chain spectrophotometric assays for clinical diagnosis

(2009) F. Medja et al.   MITOCHONDRION

The emerging role of nuclear architecture in DNA repair and genome maintenance

(2009) Tom Misteli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The production of reactive oxygen species by complex I

(2008) Judy Hirst et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Premature aging in mice activates a systemic metabolic response involving autophagy induction

(2008) Guillermo Mariño et al.   HUMAN MOLECULAR GENETICS

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

(2008) Jesús Espada et al.   JOURNAL OF CELL BIOLOGY

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hutchinson–Gilford Progeria Syndrome

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Phenotype and Course of Hutchinson–Gilford Progeria Syndrome

(2008) Melissa A. Merideth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Central and Peripheral Regulation of Food Intake and Physical Activity: Pathways and Genes

(2008) Natalie R. Lenard et al.   Obesity