Article
Clinical Neurology
Jia Xian-hao, Gao Zhen, Yuan Ya-sheng, Zhao Wei-dong
Summary: Resection of vestibular schwannomas originating from the inferior vestibular nerve extending into the fundus of the internal auditory canal through the middle cranial fossa approach with endoscopic assistance can facilitate complete removal of the lesion while minimizing the risk of hearing loss and facial paralysis.
WORLD NEUROSURGERY
(2022)
Article
Medicine, General & Internal
In Seok Moon, Ick Soo Choi, Seung Ho Shin, Seungjoon Yang, Youngrak Jung, Gina Na
Summary: This study introduces a keyhole middle cranial fossa approach (KMCFA) with endoscopic assistance for the removal of vestibular schwannoma (VS). The approach allows for minimal temporal lobe manipulation, resulting in a fast recovery and invisible scar. The technique was successfully used in both cadaveric dissections and patient surgeries, demonstrating its safety, efficiency, and cosmetic outcome.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Olivia A. La Monte, Kareem O. Tawfik, Usman Khan, Marc Schwartz, Rick Friedman
Summary: This study aims to investigate the effect of preoperative hearing on hearing preservation after middle cranial fossa (MCF) approach for resection of vestibular schwannoma (VS) and the impact of hearing preservation on disease-specific quality of life. The results showed that patients with better preoperative hearing had higher rates of hearing preservation, and postoperatively, patients with preserved hearing reported better hearing-related quality of life scores compared to those with hearing loss.
OTOLOGY & NEUROTOLOGY
(2022)
Article
Clinical Neurology
Christopher M. Welch, Gregory Mannarelli, Lindsey Koehler, Steven A. Telian
Summary: In patients undergoing MCF surgery for resection of VS, a persistent decrease in the amplitude of wave V of the ABR during surgery is correlated with delayed progressive sensorineural hearing loss in the operative ear.
OTOLOGY & NEUROTOLOGY
(2021)
Article
Clinical Neurology
Ricardo Ramina, Gustavo S. Jung, Felipe Constanzo, Erasmo Barros da Silva Jr
Summary: The study aimed to evaluate the effect of nerve position within the internal auditory canal on preoperative and postoperative cochlear and facial nerve function in patients with intracanalicular vestibular schwannoma. The study found that patients with tumors located between the vestibular and facial-cochlear nerves had worse outcomes in terms of facial nerve function and hearing preservation after surgery.
JOURNAL OF NEUROSURGERY
(2023)
Article
Clinical Neurology
Karol P. Budohoski, Robert C. Rennert, Steven A. Gordon, Amol Raheja, Cameron Brandon, J. Curran Henson, Mohammed A. Azab, Neil S. Patel, Michael Karsy, Richard K. Gurgel, Clough Shelton, William T. Couldwell
Summary: The middle fossa approach is effective for preserving hearing in small vestibular schwannomas. Factors such as preoperative hearing status, duration of anesthesia, and overlap between structures in the ear were found to influence hearing outcomes. Imaging characteristics can help predict the risk of hearing loss.
JOURNAL OF NEUROSURGERY
(2023)
Article
Clinical Neurology
Peter R. Dixon, Luke Wojdyla, Joshua Lee, Omid Moshtaghi, Alexander D. Claussen, Usman A. Khan, Marin A. Mcdonald, Marc S. Schwartz, Rick A. Friedman
Summary: This study aimed to predict hearing preservation rates after middle fossa approach for vestibular schwannomas using machine learning algorithms. The results showed that preoperative pure tone average and tumor position were the most influential factors for hearing preservation, and the random forest model demonstrated perfect accuracy.
OTOLOGY & NEUROTOLOGY
(2022)
Article
Clinical Neurology
Assaf Berger, Juan Diego Alzate, Kenneth Bernstein, Reed Mullen, Sean McMenomey, Daniel Jethanemest, David R. Friedmann, Eric Smouha, Erik P. Sulman, Joshua S. Silverman, J. Thomas Roland, John G. Golfinos, Douglas Kondziolka
Summary: This study evaluates hearing outcomes in patients with vestibular schwannoma (VS) during the modern era of cochlear dose restriction. The results show that factors such as age, baseline GR score, cochlear dose, and biological effective dose are correlated with hearing preservation. Increased tumor-free canal space is associated with better outcomes. Furthermore, patients who meet specific criteria have higher hearing preservation rates compared to the rest of the population.
Article
Oncology
Zhenxing Yang, Xiaoxing Xiong, Zhihong Jian, Li Du
Summary: This study investigated the effects of endoscopic-assisted microsurgery technique on the resection of large vestibular schwannoma and analyzed the prognosis of patients. The results showed that all tumors were completely removed in 16 cases and the facial nerve was anatomically preserved in 14 cases. The use of endoscopic-assisted microsurgery technique provides a wider surgical field, reduces complications, and ensures complete removal of internal auditory canal tumors.
FRONTIERS IN ONCOLOGY
(2023)
Review
Clinical Neurology
Vinod Kumar Yakkala, Marco Mammi, Nayan Lamba, Renuka Kandikatla, Bhaskar Paliwal, Hoda Elshibiny, C. Eduardo Corrales, Timothy R. Smith, Rania A. Mekary
Summary: Both surgery and stereotactic radiosurgery (SRS) have similar effects on hearing loss, dizziness, and tinnitus in the treatment of vestibular schwannoma. However, there is a higher risk of facial symmetry loss after surgery.
ACTA NEUROCHIRURGICA
(2022)
Article
Clinical Neurology
Luciano Mastronardi, Alberto Campione, Guglielmo Cacciotti, Ettore Carpineta, Carlo Giacobbo Scavo, Raffaele Roperto, Giovanni Stati, Albert A. Sufianov, Karl Schaller
Summary: Microsurgery of vestibular schwannoma in patients aged 40 or less is associated with good functional results and high rates of total or near-total tumor removal. Patients under 30 years of age tend to have larger, more hypervascularized tumors with more bleeding during surgery and worse long-term functional outcomes compared to those in their fourth decade of life. Limited experience suggests that near-total resection should be preferred for very young patients with large, adherent, hypervascularized tumors to maximize resection and preserve function.
NEUROSURGICAL REVIEW
(2022)
Article
Clinical Neurology
Daniele Starnoni, Giulia Cossu, Rodolfo Maduri, Constantin Tuleasca, Mercy George, Raphael Maire, Mahmoud Messerer, Marc Levivier, Etienne Pralong, Roy T. Daniel
Summary: Direct electrical stimulation and recording of postauricular muscle response (PAMR) can be used to preserve cochlear nerve and hearing during surgery. Stimulation parameters of 1mA at 1Hz were found to induce cochlear response without affecting other nerves. Most patients maintained stable hearing during the surgery, with some even experiencing significant improvement.
JOURNAL OF NEUROSURGERY
(2023)
Article
Otorhinolaryngology
Catherine Sobieski, Daniel E. Killeen, Samuel L. Barnett, Bruce E. Mickey, Jacob B. Hunter, Brandon Isaacson, Joe Walter Kutz
Summary: Facial nerve outcomes one year after microsurgical resection are poorer in patients with NF2 tumors compared to sporadic tumors, particularly for tumors with a volume greater than 3 cm³ and those classified as NF2 tumors.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Article
Clinical Neurology
Felix Arlt, Johannes Kasper, Dirk Winkler, Katja Jaehne, Michael Karl Fehrenbach, Juergen Meixensberger, Caroline Sander
Summary: Intraoperative neurophysiological monitoring is crucial in vestibular schwannoma surgery to prevent nerve injury. Repeated direct nerve stimulation and a detected decreased amplitude might show facial nerve function deterioration.
FRONTIERS IN NEUROLOGY
(2022)
Review
Medicine, General & Internal
Makoto Hosoya, Takeshi Wakabayashi, Koichiro Wasano, Takanori Nishiyama, Nobuyoshi Tsuzuki, Naoki Oishi
Summary: This article reviews recent advances in the management and treatment of vestibular schwannoma, particularly in hearing preservation. By improving intraoperative monitoring systems and conducting precise genomic analysis, the treatment of vestibular schwannomas is expected to be improved.
Review
Audiology & Speech-Language Pathology
M. Rudic, I. Keogh, R. Wagner, E. Wilkinson, N. Kiros, E. Ferrary, O. Sterkers, A. Bozorg Grayeli, K. Zarkovic, N. Zarkovic
Article
Otorhinolaryngology
Milan Rudic, Winson Wong, Stuart Viner, David Strachan, Christopher Raine
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2017)
Article
Otorhinolaryngology
Yann Nguyen, Vincent Couloigner, Milan Rudic, Alexis Bozorg Grayeli, Evelyne Ferrary, Olivier Sterkers
ACTA OTO-LARYNGOLOGICA
(2009)
Article
Audiology & Speech-Language Pathology
Milan Rudic, Christine Nguyen, Yann Nguyen, Lidija Milkovic, Neven Zarkovic, Olivier Sterkers, Evelyne Ferrary, Alexis Bozorg Grayeli
AUDIOLOGY AND NEURO-OTOLOGY
(2012)
Article
Otorhinolaryngology
Milan Rudic, Richard Wagner, Eric Willkinson, Giovanni Danese, Nega Kiros, Kamelija Zarkovic, Neven Zarkovic
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2015)
Article
Biochemistry & Molecular Biology
Milan Rudic, Lidija Milkovic, Kamelija Zarkovic, Suzana Borovic-Sunjic, Olivier Sterkers, Georg Waeg, Evelyne Ferrary, Alexis Bozorg Grayeli, Neven Zarkovic
FREE RADICAL BIOLOGY AND MEDICINE
(2013)
Article
Medicine, General & Internal
Marijan Kovacic, Ana Krvavica, Milan Rudic
ACTA CLINICA CROATICA
(2015)
Article
Anthropology
Milan Rudic, Zoran Kranjcec, Natasa Lisica-Sikic, Marijan Kovacic
COLLEGIUM ANTROPOLOGICUM
(2012)
Article
Medicine, General & Internal
Ana Krvavica, Marijan Kovacic, Ivan Baraka, Milan Rudic
ACTA CLINICA CROATICA
(2011)
Article
Otorhinolaryngology
Milan Rudic, Alexis Bozorg Grayeli, Dominique Cazals-Hatem, Francoise Cyna-Gorse, Didier Bouccara, Olivier Sterkers
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2008)
Article
Dermatology
Marijan Kovacic, Milan Rudic, Ivica Nekic, Natasa Lisica-Sikic, Zoran Kranjcec, Tatjana Simurina
DERMATOLOGIC SURGERY
(2007)
Article
Anthropology
Tatjana Simurina, Simon Mikulandra, Boris Mraovic, Zdenko Sonicki, Marijan Kovacic, Boris Dzelalija, Milan Rudic
COLLEGIUM ANTROPOLOGICUM
(2006)
Article
Anthropology
M Rudic, J Milicic, D Letinic
COLLEGIUM ANTROPOLOGICUM
(2005)
Article
Immunology
Bach-Nga Pham, Milan Rudic, Didier Bouccara, Olivier Sterkers, Nadia Belmatoug, Jean-Pierre Bebear, Vincent Couloigner, Bernard Fraysse, Andre Gentine, Eugene Ionescu, Alain Robier, Jean-Pierre Sauvage, Eric Truy, Thierry Van den Abbeele, Evelyne Ferrary