Journal
SKIN PHARMACOLOGY AND PHYSIOLOGY
Volume 23, Issue 5, Pages 244-258Publisher
KARGER
DOI: 10.1159/000314699
Keywords
Octenidine dihydrochloride; Skin antisepsis; Mucous membrane antisepsis; Wound antisepsis; Antimicrobial efficacy; Local tolerance; Toxicity; Safety; Contraindications
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Octenidine dihydrochloride (octenidine) was introduced for skin, mucous membrane and wound antisepsis more than 20 years ago. Until now, a wealth of knowledge has been gained, including in vitro and animal studies on efficacy, tolerance, safety and clinical experience both from case reports and prospective controlled trials. Nowadays, octenidine is an established antiseptic in a large field of applications and represents an alternative to older substances such as chlorhexidine, polyvidone-iodine or triclosan. The review is based on the current literature and unpublished original data as well. Copyright (C) 2010 S. Karger AG, Basel
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