Extracellular Heat Shock Proteins

Hsp70 Translocates into the Plasma Membrane after Stress and Is Released into the Extracellular Environment in a Membrane-Associated Form that Activates Macrophages

(2014) V. L. Vega et al.   JOURNAL OF IMMUNOLOGY

Release of the glucose-regulated protein 94 by baby hamster kidney cells

(2012) Yulia Evdokimovskaya et al.   CELL BIOCHEMISTRY AND FUNCTION

Plasma Hsp72 (HSPA1A) and Hsp27 (HSPB1) expression under heat stress: influence of exercise intensity

(2012) Julien D. Périard et al.   CELL STRESS & CHAPERONES

Proteotoxic stress and circulating cell stress proteins in the cardiovascular diseases

(2012) Brian Henderson et al.   CELL STRESS & CHAPERONES

Ferruccio Ritossa’s scientific legacy 50 years after his discovery of the heat shock response: a new view of biology, a new society, and a new journal

(2012) Antonio De Maio et al.   CELL STRESS & CHAPERONES

The link between small heat shock proteins and the immune system

(2012) Johannes M. van Noort et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Extracellular heat shock protein 72 protects schwann cells from hydrogen peroxide-induced apoptosis

(2012) Xinjing Luo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cell Line Specific Modulation of Extracellular Aβ42 by Hsp40

(2012) Anna Carnini et al.   PLoS One

Secreted heat shock protein-90 (Hsp90) in wound healing and cancer

(2011) Wei Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Extracellular HSPA1A promotes the growth of hepatocarcinoma by augmenting tumor cell proliferation and apoptosis-resistance

(2011) Feng-Hua Wu et al.   CANCER LETTERS

Detection of Hsp60 in saliva and serum from type 2 diabetic and non-diabetic control subjects

(2011) Jing Yuan et al.   CELL STRESS & CHAPERONES

Extracellular Heat Shock Protein 70 Induces Cardiomyocyte Inflammation and Contractile Dysfunction via TLR2

(2011) Sumeet Mathur et al.   CIRCULATION JOURNAL

Molecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity

(2011) Daming Zuo et al.   FASEB JOURNAL

Extracellular heat shock protein 90 plays a role in translocating chaperoned antigen from endosome to proteasome for generating antigenic peptide to be cross-presented by dendritic cells

(2011) J. Oura et al.   INTERNATIONAL IMMUNOLOGY

Small Heat Shock Proteins Induce a Cerebral Inflammatory Reaction

(2011) I. B. Bruinsma et al.   JOURNAL OF NEUROSCIENCE

A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α–positive tumors

(2011) Divya Sahu et al.   MOLECULAR BIOLOGY OF THE CELL

The Soluble Recombinant Neisseria meningitidis Adhesin NadAΔ351–405 Stimulates Human Monocytes by Binding to Extracellular Hsp90

(2011) Paola Cecchini et al.   PLoS One

Extracellular heat shock protein HSP90β secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-β1

(2010) Shigeki Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation

(2010) Jessica McCready et al.   BMC CANCER

Heat shock proteins as biomarkers for the rapid detection of brain and spinal cord ischemia: a review and comparison to other methods of detection in thoracic aneurysm repair

(2010) James G. Hecker et al.   CELL STRESS & CHAPERONES

Plasma levels of Hsp70 and anti-Hsp70 antibody predict risk of acute coronary syndrome

(2010) Xiaomin Zhang et al.   CELL STRESS & CHAPERONES

Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: A form of communication during injury, infection, and cell damage

(2010) Antonio De Maio   CELL STRESS & CHAPERONES

Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP

(2010) Yi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular chaperones and protein-folding catalysts as intercellular signaling regulators in immunity and inflammation

(2010) Brian Henderson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

(2010) Thomas Kirkegaard et al.   NATURE

Hsp60 Is Actively Secreted by Human Tumor Cells

(2010) Anna M. Merendino et al.   PLoS One

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib

(2009) J. Kern et al.   BLOOD

Monoclonal antibody to novel cell surface epitope on Hsc70 promotes morphogenesis of bile ducts in newborn rat liver

(2009) David R. Mills et al.   CELL STRESS & CHAPERONES

Circulating heat shock protein 70 (HSPA1A) in normal and pathological pregnancies

(2009) Attila Molvarec et al.   CELL STRESS & CHAPERONES

Extracellular Heat Shock Protein 60, Cardiac Myocytes, and Apoptosis

(2009) Se-Chan Kim et al.   CIRCULATION RESEARCH

Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells

(2009) Daniela Schilling et al.   FASEB JOURNAL

Chaperokine Function of Recombinant Hsp72 Produced in Insect Cells Using a Baculovirus Expression System Is Retained

(2009) Hongying Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Converging concepts of protein folding in vitro and in vivo

(2009) F Ulrich Hartl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Serum Heat Shock Protein 27 Is Increased in Chronic Pancreatitis and Pancreatic Carcinoma

(2009) Wei-Chih Liao et al.   PANCREAS

Unconventional Mechanisms of Protein Transport to the Cell Surface of Eukaryotic Cells

(2008) Walter Nickel et al.   Annual Review of Cell and Developmental Biology

Expression of heat shock protein 90 at the cell surface in human neuroblastoma cells

(2008) Cristina Cid et al.   CELL STRESS & CHAPERONES

Guidelines for the nomenclature of the human heat shock proteins

(2008) Harm H. Kampinga et al.   CELL STRESS & CHAPERONES

Elevated Heat Shock Protein 60 Levels Are Associated With Higher Risk of Coronary Heart Disease in Chinese

(2008) Xiaomin Zhang et al.   CIRCULATION

Calcium Signaling in Dendritic Cells by Human or Mycobacterial Hsp70 Is Caused by Contamination and Is Not Required for Hsp70-mediated Enhancement of Cross-presentation

(2008) Henriette Bendz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transforming Growth Factor   (TGF )-Stimulated Secretion of HSP90 : Using the Receptor LRP-1/CD91 To Promote Human Skin Cell Migration against a TGF -Rich Environment during Wound Healing

(2008) C.-F. Cheng et al.   MOLECULAR AND CELLULAR BIOLOGY

THE ROLE OF ENDOGENOUSLY PRODUCED EXTRACELLULAR HSP72 IN MONONUCLEAR CELL REPROGRAMMING

(2008) Patricia A. Abboud et al.   SHOCK

The effect of stress-inducible extracellular Hsp72 on human neutrophil chemotaxis: A role during acute intense exercise

(2008) Eduardo Ortega et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

The dual immunoregulatory roles of stress proteins

(2008) Alan Graham Pockley et al.   TRENDS IN BIOCHEMICAL SCIENCES