Nonhematopoietic Toll-Like Receptor 2 Contributes to Neutrophil and Cardiac Function Impairment During Polymicrobial Sepsis

Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.

(2011) Edwina Naik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

(2011) Ariel C. Bulua et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bone marrow MyD88 signaling modulates neutrophil function and ischemic myocardial injury

(2010) Yan Feng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Temporal Trends in the Epidemiology of Severe Postoperative Sepsis after Elective Surgery

(2010) Brian T. Bateman et al.   ANESTHESIOLOGY

Toll-like receptor 2 plays a critical role in cardiac dysfunction during polymicrobial sepsis*

(2010) Lin Zou et al.   CRITICAL CARE MEDICINE

Does polymicrobial sepsis exert cardiac dysfunction directly through toll-like receptor 2?*

(2010) Jan Mersmann et al.   CRITICAL CARE MEDICINE

TLR2 enhances NADPH oxidase activity and killing of Staphylococcus aureus by PMN

(2010) Naja J. Jann et al.   IMMUNOLOGY LETTERS

Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10

(2010) Kindra M. Kelly-Scumpia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice

(2010) Manabu Kinoshita et al.   JOURNAL OF HEPATOLOGY

NADPH Oxidase-Dependent Reactive Oxygen Species Mediate Amplified TLR4 Signaling and Sepsis-Induced Mortality in Nrf2-Deficient Mice

(2010) X. Kong et al.   JOURNAL OF IMMUNOLOGY

Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis

(2009) J. C. Alves-Filho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune adaptor MyD88 mediates neutrophil recruitment and myocardial injury after ischemia-reperfusion in mice

(2008) Yan Feng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart

(2008) Wei Chao   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival

(2008) O. M. Peck-Palmer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

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(2008) Michael Flierl et al.   MOLECULAR MEDICINE