Establishment and characterization of patient-derived tumor xenograft using gastroscopic biopsies in gastric cancer

Mouse Models of Human Cancer

(2014) Barbara C. Böck et al.   CANCER RESEARCH

HER2 screening data from ToGA: targeting HER2 in gastric and gastroesophageal junction cancer

(2014) Eric Van Cutsem et al.   Gastric Cancer

Patient-Derived Tumor Xenografts: Transforming Clinical Samples into Mouse Models

(2013) D. Siolas et al.   CANCER RESEARCH

Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer

(2013) A. Spreafico et al.   CLINICAL CANCER RESEARCH

Ramucirumab: a novel antiangiogenic agent

(2013) Roopma Wadhwa et al.   Future Oncology

Apatinib for Chemotherapy-Refractory Advanced Metastatic Gastric Cancer: Results From a Randomized, Placebo-Controlled, Parallel-Arm, Phase II Trial

(2013) Jin Li et al.   JOURNAL OF CLINICAL ONCOLOGY

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Trastuzumab for the Treatment of HER2-Positive Metastatic Gastric Cancer

(2013) Eldon Spackman et al.   PHARMACOECONOMICS

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

A subset of gastric cancers with EGFR amplification and overexpression respond to cetuximab therapy

(2013) Lianhai Zhang et al.   Scientific Reports

Patient-Derived Xenograft Models to Improve Targeted Therapy in Epithelial Ovarian Cancer Treatment

(2013) Clare L. Scott et al.   Frontiers in Oncology

Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer

(2012) S. Julien et al.   CLINICAL CANCER RESEARCH

A Validated Tumorgraft Model Reveals Activity of Dovitinib Against Renal Cell Carcinoma

(2012) S. Sivanand et al.   Science Translational Medicine

Pertuzumab in Combination with Trastuzumab Shows Significantly Enhanced Antitumor Activity in HER2-Positive Human Gastric Cancer Xenograft Models

(2011) Y. Yamashita-Kashima et al.   CLINICAL CANCER RESEARCH

Orthotopic xenografts of RCC retain histological, immunophenotypic and genetic features of tumours in patients

(2011) Chiara Grisanzio et al.   JOURNAL OF PATHOLOGY

Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

(2011) Yoko S DeRose et al.   NATURE MEDICINE

Cryopreservation of human colorectal carcinomas prior to xenografting

(2010) Michael Linnebacher et al.   BMC CANCER

Patient-derived human tumour tissue xenografts in immunodeficient mice: a systematic review

(2010) Ketao Jin et al.   Clinical & Translational Oncology

Patient-Derived First Generation Xenografts of Non-Small Cell Lung Cancers: Promising Tools for Predicting Drug Responses for Personalized Chemotherapy

(2010) X. Dong et al.   CLINICAL CANCER RESEARCH

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

(2010) Yung-Jue Bang et al.   LANCET

Synergistic Antitumor Effect of S-1 and HER2-Targeting Agents in Gastric Cancer with HER2 Amplification

(2010) J. Tanizaki et al.   MOLECULAR CANCER THERAPEUTICS

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro

(2009) V. C. Daniel et al.   CANCER RESEARCH

The impact of next-generation sequencing technology on genetics

(2008) Elaine R. Mardis   TRENDS IN GENETICS