4.7 Article

Self-assembled magnetoplasmonic nanochain for DNA sensing

Journal

SENSORS AND ACTUATORS B-CHEMICAL
Volume 203, Issue -, Pages 817-823

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2014.07.040

Keywords

Fe3O4@Au core-shell NP; 1D assembly; Magnetoplasmonics; DNA biosensor; Nanochain

Funding

  1. Ministry of Health & Welfare, Republic of Korea [HI13C0862]
  2. National Research Foundation of Korea (NRF) - Ministry of Education [2013004637, 2014R1A1A2007222]
  3. National Fisheries Research & Development Institute [RP-2012-BT-070]
  4. National Research Foundation of Korea [2014R1A1A2007222] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A method is proposed for the subtle control of multifunctional nanoparticles by applying an externalmagnetic field to induce a 1D assembly. Au coated Fe3O4 core-shell nanoparticles (Fe3O4@ Au NPs) wereused to fabricate conducting magnetoplasmonic nanochains (MPNCs). Fe3O4@ Au NPs were synthesizedin an aqueous solution by a one-step reaction, showing superparamagnetic property, and were welldispersed and stable in water at physiological pH. The MPNCs were prepared on a solid substrate throughmagneticfield- induced alignment of Fe3O4@ Au NPs. The dimension of these MPNCs is simply controlledby adjusting magnetic field strength. In order to utilize MPNCs as sensing platform, an annealing step wasperformed to improve their electrical properties. The annealed MPNCs were used as electrical transducersfor DNA detection by successively immobilizing DNA probe on MPNCs and hybridizing them with targetDNA. A direct detection of the electrical changes was performed using linear sweep voltammetry (LSV). A significant resistance increase was observed upon hybridization of the target DNA to the probe DNAon MPNCs. (C) 2014 Elsevier B. V. All rights reserved. As one of the most important spinel-type materials with poten-

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