Article
Chemistry, Multidisciplinary
Maegen Kincanon, Catherine J. Murphy
Summary: The self-assembly of colloidal nanocrystals is of great interest for creating hierarchical nanomaterials with advanced function. Gold nanocrystals can enhance local electric fields and provide plasmonic fields for surface-enhanced spectroscopies. A selective biotinylation method was developed for gold nanorods, allowing for self-assembly upon addition of streptavidin. The self-assembly was analyzed for different sized nanorods, showing high yield for larger nanorods and low yield for smaller nanorods.
Article
Biophysics
Xianqiang Song, Xin Chen, Zhaoxiong Liang, Dan Xu, Yong Liang
Summary: This study developed a sensor platform based on gold nanobipyramids@silver nanorods for the quantitative, visual, and sensitive detection of Cr3+ ions in aqueous solutions. The method relies on the absorbance change of the nanorods induced by Cr3+ and can achieve a detection limit of 8.7 nM using a UV-vis spectrophotometer-based colorimetric detection method. The sensor shows high sensitivity, selectivity, and performance, making it useful for on-site quantitative detection of Cr3+ ions in water samples.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Sanyukta Mayuri, Niki Sweta Jha, Shailendra Kumar Jha
Summary: We report here a gold nanorod-based optical sensing platform induced by curcumin for the detection of specific DNA targets. The platform shows high sensitivity and selectivity, making it suitable for DNA detection related to cancer cells.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Analytical
Min Li, Yi-Na Cai, Chi-Fang Peng, Xin-Lin Wei, Zhou-Ping Wang
Summary: This study presents copper nano-assemblies with aggregation-induced emission enhancement property using DNA dendrimers as template, showing excellent sensitivity and selectivity for fluorescent detection of Pb2+ ions. DNA dendrimers with 27 bases sticky end exhibited superior performance in fluorescence enhancement.
Article
Polymer Science
Bin Liu, Weiya Li, Etienne Duguet, Serge Ravaine
Summary: Self-assembly of nanosized building blocks is an efficient strategy for producing organized materials. In this study, the chaining of silica nanoparticles with polystyrene patches dispersed in tetrahydrofuran is investigated. The influence of patch-to-particle size ratio and the nature of the added nonsolvent are studied, showing that the chains can cyclize beyond a certain length. The addition of one-patch silica nanoparticles is also shown to control the length of the chains.
Review
Biochemistry & Molecular Biology
Qida Zong, Naijun Dong, Xiaotong Yang, Guixia Ling, Peng Zhang
Summary: Gold nanorods (GNRs) have attracted increasing attention for tumor therapy due to their unique properties, although issues such as stability and toxicity have hindered their clinical application. Research is ongoing to investigate the toxic effects of GNRs, factors influencing toxicity, and methods to enhance biocompatibility for future development and safe utilization in tumor treatments.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Pramod Kumar Mehta, JaeYoon Lee, Eun-Taex Oh, Heon Joo Park, Keun-Hyeung Lee
Summary: In this study, fluorescent probes for ratiometric detection of Pb2+ in aqueous solution and living cells were developed based on Peptide receptors. Through the synthesis and investigation of different fluorescent probes, benzothiazolyl-cyanovinylene was determined as an appropriate fluorophore for ratiometric detection of Pb2+. Furthermore, by modifying the peptide receptors, two fluorescent probes with remarkable ratiometric sensing properties for Pb2+ were developed.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Food Science & Technology
Xia Xu, Xiaotian Wu, Yuting Ding, Xuxia Zhou
Summary: The study developed a novel biosensor for the rapid and specific detection of histamine in fish samples, showing great potential for on-site detection of various analytes with high accuracy.
Article
Chemistry, Physical
Abeer Fahes, Aotmane En Naciri, Mohamad Baker Shoker, Suzanna Akil
Summary: Two distinct Ag/Au nanocomposites, namely, hetero-oligomers and eccentric core/shells were obtained. The structures of the final products were controlled by Ag concentration-dependent, facet-specific passivation, and presence or absence of anisotropic facets. Ag additives acted as shape-directing agents due to an underpotential deposition (UPD) that stabilized the various surface facets of the AuNPs.
Article
Chemistry, Multidisciplinary
Da Li, Julien Brunie, Fan Sun, Philippe Nizard, Delphine Onidas, Aazdine Lamouri, Vincent Noel, Claire Mangeney, Giorgio Mattana, Yun Luo
Summary: A new generation of SERS security labels based on silver nanoparticles functionalized by aryl diazonium salts with distinguishable Raman fingerprints was developed in this study. The remarkable potential of diazonium salt chemistry to design Ag NPs-based SERS security labels was confirmed through proof-of-concept Raman imaging experiments and their successful application in ink printing.
NANOSCALE ADVANCES
(2022)
Article
Electrochemistry
Anna M. Nelson, Sanaz Habibi, Jaesung Lee, Mark A. Burns
Summary: To address the need for timely and onsite monitoring of lead in drinking water, a four-electrode system was designed to detect the presence of lead. By studying the deposition mechanism of lead on the sensor, the detection time and reliability of the sensor were improved and reduced.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Jing Li, Huayi Shi, Runzhi Chen, Xiaofeng Wu, Jiayi Cheng, Fenglin Dong, Houyu Wang, Yao He
Summary: The synthesis of programmable atom-like nanoparticles (PANs) with high valences and high yields remains a challenge. A novel synthetic strategy using microfluidic galvanic displacement (mu-GD) and microfluidic DNA nanoassembly was developed for the synthesis of single-stranded DNA encoder (SSE)-encoded PANs. This method allows for the effective control of interfacial reactions and has led to the successful synthesis of PANs with high valences (e.g., n-valence, n = 12) and high yields (>80%). The first demonstration of a PAN-based automatic analytical platform was presented, showing reliable quantitative measurement with accurate determination of tetracycline (TET) in serum and milk samples.
Article
Chemistry, Multidisciplinary
Weiqiu Kang, Xianhe Gao, Hongbo Li, Yang Wei, Chao Wang, Ziqi Tian
Summary: An efficient approach is reported to induce the hierarchical self-assembly of perovskite CsPbBr3 nanocrystals by phase transition, which leads to the formation of asymmetric Cs4PbBr6 nanorods with circularly polarized luminescent response. The conversion process from CsPbBr3 nanocubes to Cs4PbBr6 nanocrystals is found to involve an interface phase transition initiated by cysteine molecules. The Cs4PbBr6 nanocrystals then sequentially aggregate to form nanoclusters, which further self-assemble into chiral Cs4PbBr6 nanorods. Molecular dynamics simulations reveal the gradual approach of Cs4PbBr6 nanochains to form an asymmetric structure, supported by the simulated circular dichroism spectrum.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
Amrita Chakraborty, Nonappa, Biswajit Mondal, Kamalesh Chaudhari, Heikki Rekola, Ville Hynninen, Mauri A. Kostiainen, Robin H. A. Ras, Thalappil Pradeep
Summary: This study presents an efficient and simple strategy to grow precision helical hybrid microwires by systematically assembling cationic gold nanorods along chiral tobacco mosaic virus particles via electrostatic attraction. The resulting composite superstructures exhibit a strong circular dichroism response at the plasmon wavelength of the gold nanorods. This generic methodology using inexpensive templates encourages the exploration of a wider range of nanoscale templates for creating hybrid mesostructures with emerging optoelectronic properties.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Xudong Peng, Mengmeng Zhang, Feng Xue, Aodi Zhang, Yue Xu, Yi Huang, Hong Wang, Hongyu Chen
Summary: Salt-induced aggregation is a convenient method for obtaining chains of small Au nanoparticles (<15 nm), but often leads to branched and globular aggregates as by-products. By investigating the mechanism and designing reaction conditions, we found that modulating ligand concentration and solvent polarity are more effective for precise chain aggregation, consistent with DLVO theory. Our method can be applied to noble metal nanoparticles of various sizes with different ligands, including SERS-active ones, producing chain aggregates with low error ratio (around 4%).
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)